نتائج البحث - "Timothy M. Horton"

1

دورية أكاديمية

Protocol for determining zinc-dependent β cell-selective small-molecule delivery in mouse pancreas

المؤلفون: Timothy M. Horton, Benjamin R. Kraemer, Justin P. Annes

المصدر: STAR Protocols, Vol 2, Iss 1, Pp 100263- (2021)

مصطلحات موضوعية: Cell biology, Cell-based assays, Model organisms, Molecular/chemical probes, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2666166720302501Test; https://doaj.org/toc/2666-1667Test

الوصول الحر: https://doaj.org/article/f25539b332de466ab1c0549af7dbe774Test

View record in DOAJ

النص الكامل

2

Abstract 3674: The polyamine acetylation enzyme SAT1 drives mesenchymal features and therapeutic resistance in glioblastoma

المؤلفون: Ayush B. Rana, Timothy M. Horton, Vijay S. Thakur, Scott M. Welford

المصدر: Cancer Research. 83:3674-3674

مصطلحات موضوعية: Cancer Research, Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::352e31e78ef080184bd90ba3fb94193fTest
https://doi.org/10.1158/1538-7445.am2023-3674Test

3

دورية أكاديمية

Metabolomics analyses identify platelet activating factors and heme breakdown products as Lassa fever biomarkers.

المؤلفون: Trevor V Gale, Timothy M Horton, Donald S Grant, Robert F Garry

المصدر: PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005943 (2017)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

العلاقة: http://europepmc.org/articles/PMC5619842?pdf=renderTest; https://doaj.org/toc/1935-2727Test; https://doaj.org/toc/1935-2735Test; https://doaj.org/article/43cd1dea555b4106b220ff964f8f9bb5Test

الإتاحة: https://doi.org/10.1371/journal.pntd.0005943Test
https://doaj.org/article/43cd1dea555b4106b220ff964f8f9bb5Test

View record in BASE

النص الكامل

4

PAM staining intensity of primary neuroendocrine neoplasms is a potential prognostic biomarker

المؤلفون: Vandana Sundaram, Christine H. Lee, Kaisha N. Benjamin, Teri A. Longacre, Kathleen Hornbacker, Pamela L. Kunz, Allison Zemek, Aidan Van Vleck, Timothy M. Horton, Justin P. Annes

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, lcsh:Medicine, Disease, Gastroenterology, Article, Mixed Function Oxygenases, Tumour biomarkers, Prognostic markers, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Internal medicine, parasitic diseases, Biomarkers, Tumor, Humans, Medicine, Prognostic biomarker, In patient, Stage (cooking), lcsh:Science, reproductive and urinary physiology, Aged, Aged, 80 and over, Multidisciplinary, Tumor size, business.industry, Stomach, lcsh:R, Middle Aged, Prognosis, Immunohistochemistry, Staining, Survival Rate, Neuroendocrine Tumors, Neuroendocrine cancer, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Amidine-Lyases, embryonic structures, Female, lcsh:Q, business, Follow-Up Studies, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c6dbbab213b446983bf2d786569811Test
http://link.springer.com/article/10.1038/s41598-020-68071-6Test

5

Novel Pathogenic De Novo INS p.T97P Variant Presenting With Severe Neonatal DKA

المؤلفون: Rayhan A Lal, Hannah P Moeller, Ella A Thomson, Timothy M Horton, Sooyeon Lee, Raquel Freeman, Priya Prahalad, Ada S Y Poon, Justin P Annes

المصدر: Endocrinology

مصطلحات موضوعية: Male, Models, Molecular, Protein Folding, Endocrinology, Brief Report, Diabetes Mellitus, Mutation, Missense, Humans, Infant, Insulin, Diabetic Ketoacidosis, Proinsulin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e59c942b60860492cab556157be81e1Test
https://pubmed.ncbi.nlm.nih.gov/34888628Test

6

Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimization

المؤلفون: Mark Smith, Justin P. Annes, Paul Allegretti, Benjamin Yeh, Matthew Caffet, Yassan Abdolazimi, Timothy M. Horton, Hannah P. Moeller, Guillermina Michel

المصدر: Bioorg Med Chem

مصطلحات موضوعية: DYRK1A, Clinical Biochemistry, Pharmaceutical Science, Protein Serine-Threonine Kinases, 01 natural sciences, Biochemistry, Article, Small Molecule Libraries, Structure-Activity Relationship, In vivo, Insulin-Secreting Cells, Drug Discovery, Humans, Insulin, Inducer, Naphthyridines, Cytotoxicity, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, Binding Sites, 010405 organic chemistry, Kinase, Chemistry, Regeneration (biology), Organic Chemistry, Cell cycle, Protein-Tyrosine Kinases, Small molecule, 0104 chemical sciences, Cell biology, Protein Structure, Tertiary, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Kinetics, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c14bde7a6a312e8cc57343ff6fb1caTest
https://pubmed.ncbi.nlm.nih.gov/31757680Test

7

Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors

المؤلفون: Luis M. Branco, Robert F. Garry, Timothy M. Horton, Trevor V. Gale, Andrew R. Hoffmann

المصدر: Journal of Proteome Research.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49869bd0545eb9cfaa96fc22d844b1bTest
https://doi.org/10.1021/acs.jproteome.8b00204Test

8

Structure of the IFNγ receptor complex guides design of biased agonists

المؤلفون: Steven J. Berardinelli, Naotaka Tsutsumi, Jacob Piehler, Leon Su, Timothy M. Horton, K. Christopher Garcia, Nichole K. Escalante, Edgar G. Engleman, Kevin Jude, Robert S. Haltiwanger, Junel Sotolongo Bellón, Juan L. Mendoza

المصدر: Nature. 567(7746)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Receptor complex, medicine.medical_treatment, Major histocompatibility complex, Ligands, Article, B7-H1 Antigen, 03 medical and health sciences, Interferon-gamma, Structure-Activity Relationship, 0302 clinical medicine, Downregulation and upregulation, Interferon, Cell Line, Tumor, medicine, Humans, Receptor, Receptors, Interferon, Mycobacterium Infections, Multidisciplinary, biology, Chemistry, Protein Stability, Gene Expression Profiling, Histocompatibility Antigens Class I, Acquired immune system, Cell biology, Drug Partial Agonism, 030104 developmental biology, Cytokine, Gene Expression Regulation, 030220 oncology & carcinogenesis, Drug Design, Mutation, biology.protein, Signal transduction, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d49b7e4391c71ba11206a09513f7c8Test
https://pubmed.ncbi.nlm.nih.gov/31131497Test

9

CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition

المؤلفون: Hannah P. Moeller, Justin P. Annes, Mark Smith, Neali A Armstrong, Yassan Abdolazimi, Sooyeon Lee, Timothy M. Horton, Benjamin Yeh, David McCutcheon, Haixia Xu, Robert J. Nichols, Paul Allegretti, Aryaman Shalizi, Zhengshan Zhao

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Receptor, Transforming Growth Factor-beta Type I, Cell Cycle Proteins, In Vitro Techniques, Protein Serine-Threonine Kinases, 03 medical and health sciences, Endocrinology, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Humans, Pyrazolones, Receptor, E2F, Research Articles, Cell Proliferation, Glycogen Synthase Kinase 3 beta, NFATC Transcription Factors, Chemistry, Kinase, Forkhead Box Protein M1, JNK Mitogen-Activated Protein Kinases, NFAT, Kv Channel-Interacting Proteins, Cell cycle, Middle Aged, Protein-Tyrosine Kinases, Cell biology, Rats, Repressor Proteins, 030104 developmental biology, Trans-Activators, Phosphorylation, Female, Signal transduction, Cyclin-Dependent Kinase Inhibitor p27, Transforming growth factor, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d23618a08522a31d31e5fde9a0b579aTest
https://europepmc.org/articles/PMC6287593Test/

10

Metabolomics analyses identify platelet activating factors and heme breakdown products as Lassa fever biomarkers

المؤلفون: Robert F. Garry, Timothy M. Horton, Trevor V. Gale, Donald S. Grant

المصدر: PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005943 (2017)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: 0301 basic medicine, Male, Viral Diseases, Physiology, Fulminant, medicine.disease_cause, Antibodies, Viral, Biochemistry, Mass Spectrometry, chemistry.chemical_compound, 0302 clinical medicine, Animal Cells, Medicine and Health Sciences, Metabolites, Medicine, Platelet, Enzyme-Linked Immunoassays, Lassa fever, Antigens, Viral, biology, Organic Compounds, lcsh:Public aspects of medicine, 3. Good health, Body Fluids, Africa, Western, Chemistry, Infectious Diseases, Blood, Physical Sciences, RNA, Viral, Female, Antibody, Anatomy, Cellular Types, Research Article, Neglected Tropical Diseases, Biotechnology, Adult, Platelets, lcsh:Arctic medicine. Tropical medicine, Adolescent, lcsh:RC955-962, 030231 tropical medicine, Heme, Research and Analysis Methods, Viral hemorrhagic fever, Sierra leone, Sierra Leone, 03 medical and health sciences, Young Adult, Lassa Fever, Diagnostic Medicine, Humans, Metabolomics, Platelet Activating Factor, Lassa virus, Immunoassays, Viral Hemorrhagic Fevers, Blood Cells, Platelet-activating factor, business.industry, Organic Chemistry, Public Health, Environmental and Occupational Health, Chemical Compounds, Biology and Life Sciences, lcsh:RA1-1270, Cell Biology, medicine.disease, Tropical Diseases, Virology, 030104 developmental biology, Metabolism, chemistry, Immunoglobulin M, Small Molecules, Immunology, biology.protein, Immunologic Techniques, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2469b9aa60c3fe648f5649ec95363919Test
http://europepmc.org/articles/PMC5619842?pdf=renderTest

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