يعرض 1 - 10 نتائج من 23 نتيجة بحث عن '"Timothy M. Costigan"', وقت الاستعلام: 1.24s تنقيح النتائج
  1. 1
    Similar Efficacy and Safety of Basaglar® and Lantus® in Patients with Type 2 Diabetes in Age Groups (< 65 Years, ≥ 65 Years): A Post Hoc Analysis from the ELEMENT-2 Study

    المؤلفون: Liza L. Ilag, Timothy M. Costigan, Robyn K. Pollom, LB Lacaya, Priscilla Hollander

    المصدر: Diabetes Therapy

    مصطلحات موضوعية: medicine.medical_specialty, Efficacy, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Subgroup analysis, Type 2 diabetes, Hypoglycemia, 03 medical and health sciences, chemistry.chemical_compound, Age, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Insulin, 030212 general & internal medicine, Original Research, business.industry, Insulin glargine, medicine.disease, chemistry, Glycated hemoglobin, Safety, business, Body mass index, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf710e748123a687edc1bc0a2ec25f06Test
    https://doi.org/10.1007/s13300-018-0405-5Test


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  2. 2
    Evaluation of immunogenicity of LY2963016 insulin glargine compared with Lantus® insulin glargine in patients with type 1 or type 2 diabetes mellitus

    المؤلفون: Thomas Blevins, Steve Edelman, R. A. Ortmann, Timothy M. Costigan, Melvin J. Prince, J. S. Zielonka, Mark A. Deeg, Robert J. Konrad, Liza L. Ilag, Robyn K. Pollom, W. J. Huster, Priscilla Hollander

    المصدر: Diabetes, Obesity & Metabolism

    مصطلحات موضوعية: medicine.medical_specialty, LY2963016 insulin glargine, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Insulin Antibodies, Insulin Glargine, 030209 endocrinology & metabolism, Insulin Antibody, 030204 cardiovascular system & hematology, Hypoglycemia, Cross Reactions, Drug Hypersensitivity, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Double-Blind Method, Internal medicine, Insulin, Regular, Human, Internal Medicine, medicine, Humans, Hypoglycemic Agents, In patient, Immunogenetic Phenomena, Biosimilar Pharmaceuticals, business.industry, Insulin glargine, Immunogenicity, Incidence, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, Cross reactions, Original Articles, medicine.disease, Recombinant Proteins, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hyperglycemia, Asymptomatic Diseases, Original Article, insulin antibody, business, biosimilar insulin, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7cd1d91c5af5483c4f4d9e304aab47Test
    http://europepmc.org/articles/PMC4737399Test


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  3. 3
    Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel

    المؤلفون: Joseph A. Jakubowski, Elliott M. Antman, Stephen D. Wiviott, Franz-Josef Neumann, Debra L. Miller, Alan D. Michelson, Timothy M. Costigan, Andrew L. Frelinger, Dietmar Trenk, Carolyn H. McCabe, Eugene Braunwald

    المصدر: Thrombosis and Haemostasis. 106:219-226

    مصطلحات موضوعية: Male, 0301 basic medicine, Ticlopidine, Prasugrel, Thienopyridine, Thiophenes, 030204 cardiovascular system & hematology, Pharmacology, Loading dose, Piperazines, 03 medical and health sciences, 0302 clinical medicine, P2Y12, Double-Blind Method, Purinergic P2 Receptor Antagonists, Humans, Medicine, Platelet, Platelet Activating Factor, Aged, Cross-Over Studies, Prasugrel Hydrochloride, business.industry, Maintenance dose, Hematology, Middle Aged, Clopidogrel, Receptors, Purinergic P2Y12, Adenosine Diphosphate, 030104 developmental biology, Female, business, Platelet Aggregation Inhibitors, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402062876f37b10d41a4189404172e71Test
    https://doi.org/10.1160/th11-03-0185Test


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  4. 4
    Increased Platelet Inhibition After Switching From Maintenance Clopidogrel to Prasugrel in Patients With Acute Coronary Syndromes

    المؤلفون: Andrew L. Frelinger, Clement K. Ojeh, Paul A. Gurbel, Dominick J. Angiolillo, Roger DeRaad, Joseph A. Jakubowski, Jorge F. Saucedo, Mark B. Effron, Timothy M. Costigan

    المصدر: Journal of the American College of Cardiology. 56(13):1017-1023

    مصطلحات موضوعية: Acute coronary syndrome, Prasugrel, Prasugrel Hydrochloride, business.industry, Maintenance dose, medicine.medical_treatment, Percutaneous coronary intervention, Clopidogrel, medicine.disease, Loading dose, P2Y12, Anesthesia, medicine, cardiovascular diseases, business, Cardiology and Cardiovascular Medicine, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e0d5a8d41291f18155a264e7dbb56fTest


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  5. 5
    Cardiovascular Safety Update of Tadalafil: Retrospective Analysis of Data from Placebo-Controlled and Open-Label Clinical Trials of Tadalafil With As Needed, Three Times-per-Week or Once-a-Day Dosing

    المؤلفون: Murray A. Mittleman, Graham Jackson, Melanie Chan, Adolph M. Hutter, G. Matthew Vail, Margaret R. Warner, Robert A. Kloner, Timothy M. Costigan

    المصدر: The American Journal of Cardiology. 97:1778-1784

    مصطلحات موضوعية: Male, medicine.medical_specialty, Phosphodiesterase Inhibitors, Population, Myocardial Infarction, Hyperlipidemias, Comorbidity, Coronary Artery Disease, Placebo, Drug Administration Schedule, Tadalafil, Coronary artery disease, Erectile Dysfunction, Internal medicine, Diabetes Mellitus, medicine, Humans, Myocardial infarction, Adverse effect, education, Aged, Retrospective Studies, Clinical Trials as Topic, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Middle Aged, medicine.disease, Clinical trial, Erectile dysfunction, Anesthesia, Hypertension, Cardiology, Cardiology and Cardiovascular Medicine, business, Carbolines, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fc5ec7d802be4dd69f01d6d564d7caTest
    https://doi.org/10.1016/j.amjcard.2005.12.073Test


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  6. 6
    The Combined Use of Ibutilide as an Active Control With Intensive Electrocardiographic Sampling and Signal Averaging as a Sensitive Method to Assess the Effects of Tadalafil on the Human QT Interval

    المؤلفون: Margaret R. Warner, Charles M. Beasley, Alex Dmitrienko, Arash Bakhtyari, Robert A. Kloner, Jeremy N. Ruskin, Malcolm I. Mitchell, Michael Turik, Wei Shen, Louis R. Cantilena, Alun Bedding, Timothy M. Costigan, Jeffrey T. Emmick

    المصدر: Journal of the American College of Cardiology. 46:678-687

    مصطلحات موضوعية: Adult, Male, Time Factors, Adolescent, Phosphodiesterase Inhibitors, Long QT syndrome, Ibutilide, Placebo, QT interval, Tadalafil, law.invention, Placebos, Electrocardiography, Erectile Dysfunction, Randomized controlled trial, law, medicine, Humans, Ventricular Function, Sulfonamides, business.industry, Middle Aged, medicine.disease, Confidence interval, Electrophysiology, Long QT Syndrome, Erectile dysfunction, Case-Control Studies, Anesthesia, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents, Carbolines, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe49eb90c35b843f399b4e4cc6f99249Test
    https://doi.org/10.1016/j.jacc.2005.05.036Test


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  7. 7
    Update on Clinical Trials of Tadalafil Demonstrates No Increased Risk of Cardiovascular Adverse Events

    المؤلفون: Timothy M. Costigan, Margaret R. Warner, Robert A. Kloner, Graham Jackson, Jeffrey T. Emmick

    المصدر: The Journal of Sexual Medicine. 1:161-167

    مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Phosphodiesterase Inhibitors, Urology, Endocrinology, Diabetes and Metabolism, Myocardial Infarction, Placebo, Tadalafil, Endocrinology, Erectile Dysfunction, Risk Factors, Internal medicine, Epidemiology, Humans, Medicine, Myocardial infarction, Adverse effect, Aged, Randomized Controlled Trials as Topic, Aged, 80 and over, business.industry, Incidence (epidemiology), Middle Aged, medicine.disease, Clinical trial, Psychiatry and Mental health, Erectile dysfunction, Reproductive Medicine, Cardiovascular Diseases, Anesthesia, business, Carbolines, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559bea331f029af2905338dfd86dbf75Test
    https://doi.org/10.1111/j.1743-6109.2004.04024.xTest


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  8. 8
    A Multicenter, Randomized, Double-Blind, Crossover Study to Evaluate Patient Preference between Tadalafil and Sildenafil

    المؤلفون: Alexander von Keitz, Scott Segal, Jonathan Denne, Jeffrey T. Emmick, Daniel C. Lockhart, Charles M. Beasley, Aileen Murphy, Timothy M. Costigan, Jacob Rajfer

    المصدر: European Urology. 45:499-509

    مصطلحات موضوعية: Adult, Male, Phosphodiesterase Inhibitors, Sildenafil, Urology, Placebo, Piperazines, Sildenafil Citrate, Tadalafil, law.invention, chemistry.chemical_compound, Double-Blind Method, Erectile Dysfunction, Randomized controlled trial, law, medicine, Humans, Sulfones, Dosing, Aged, Cross-Over Studies, business.industry, Middle Aged, medicine.disease, Crossover study, respiratory tract diseases, Clinical trial, Erectile dysfunction, chemistry, Patient Satisfaction, Purines, Anesthesia, cardiovascular system, business, Carbolines, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd95faa2dc645e6f9e2aaedeae04d0e9Test
    https://doi.org/10.1016/j.eururo.2003.11.030Test


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  9. 9
    Abemaciclib for the treatment of brain metastases (BM) secondary to hormone receptor positive (HR+), HER2 negative breast cancer

    المؤلفون: Donald Thornton, Carey K. Anders, Nan Lin, P. Kellie Turner, Sara M. Tolaney, Timothy M. Costigan, Suzanne Klise

    المصدر: Journal of Clinical Oncology. 35:1019-1019

    مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Pathology, macromolecular substances, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, Internal medicine, Medicine, Dosing, Abemaciclib, biology, business.industry, Melanoma, HER2 negative, medicine.disease, Metastatic breast cancer, 030104 developmental biology, chemistry, Hormone receptor, 030220 oncology & carcinogenesis, biology.protein, bacteria, Cyclin-dependent kinase 6, business

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::627da5b972f0624880cc3582acb851e4Test
    https://doi.org/10.1200/jco.2017.35.15_suppl.1019Test


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  10. 10
    Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways

    المؤلفون: Timothy M. Costigan, Joseph R. Walker, Dominick J. Angiolillo, Neal S. Kleiman, Scott S. Sundseth, Joseph A. Jakubowski, Christoph Varenhorst, Mark B. Effron, Oscar Ö. Braun, José Luis Ferreiro, Jorge F. Saucedo, Suman Duvvuru, Kenneth J. Winters

    المصدر: Thrombosis and haemostasis. 110(6)

    مصطلحات موضوعية: Blood Platelets, Male, Acute coronary syndrome, Prasugrel, ATP Binding Cassette Transporter, Subfamily B, Ticlopidine, Thienopyridine, Pyridines, CYP2C19, Coronary Artery Disease, Thiophenes, 030204 cardiovascular system & hematology, Pharmacology, Piperazines, 03 medical and health sciences, 0302 clinical medicine, P2Y12, medicine, Humans, 030212 general & internal medicine, ATP Binding Cassette Transporter, Subfamily B, Member 1, Prospective Studies, Alleles, Biotransformation, Cells, Cultured, Aged, Polymorphism, Genetic, business.industry, Aryldialkylphosphatase, Microfilament Proteins, Vasodilator-stimulated phosphoprotein, Hematology, Middle Aged, medicine.disease, Clopidogrel, Phosphoproteins, Platelet Activation, Receptors, Purinergic P2Y12, Cytochrome P-450 CYP2C19, Pharmacodynamics, Female, Aryl Hydrocarbon Hydroxylases, business, Cell Adhesion Molecules, Prasugrel Hydrochloride, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2d0e5a0106f79e32c1d4d57107551cTest
    https://pubmed.ncbi.nlm.nih.gov/24009042Test


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