المؤلفون: Skanda Rajasundaram, Nazlee Zebardast, Puja Mehta, Anthony P. Khawaja, Alasdair Warwick, Katherine Duchinski, Stephen Burgess, Dipender Gill, Ayellet V. Segrè, Janey Wiggs

المصدر: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Intraocular pressure, Primary open-angle glaucoma, Mendelian randomization, Colocalization, TIE1, TEK, Medicine

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1479-5876Test

الوصول الحر: https://doaj.org/article/3d439713257e4f38a7603dcd3644a025Test

المؤلفون: Loukas Zagkos, Marie-Joe Dib, Héléne T. Cronjé, Paul Elliott, Abbas Dehghan, Ioanna Tzoulaki, Dipender Gill, Iyas Daghlas

المصدر: Genes, Vol 15, Iss 1, p 71 (2024)

مصطلحات موضوعية: CSF, cognition, tyrosine-protein kinase receptor, SERPING1, TIE1, Genetics, QH426-470

العلاقة: https://www.mdpi.com/2073-4425/15/1/71Test; https://doaj.org/toc/2073-4425Test; https://doaj.org/article/4b76426330484450985df94a06c22535Test

الإتاحة: https://doi.org/10.3390/genes15010071Test
https://doaj.org/article/4b76426330484450985df94a06c22535Test

المؤلفون: Zagkos, Loukas, Dib, Marie Joe, Cronjé, Héléne T., Elliott, Paul, Dehghan, Abbas, Tzoulaki, Ioanna, Gill, Dipender, Daghlas, Iyas

المصدر: Zagkos , L , Dib , M J , Cronjé , H T , Elliott , P , Dehghan , A , Tzoulaki , I , Gill , D & Daghlas , I 2024 , ' Cerebrospinal Fluid C1-Esterase Inhibitor and Tie-1 Levels Affect Cognitive Performance : Evidence from Proteome-Wide Mendelian Randomization ' , Genes , vol. 15 , no. 1 , 71 . https://doi.org/10.3390/genes15010071Test

مصطلحات موضوعية: cognition, CSF, SERPING1, TIE1, tyrosine-protein kinase receptor

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.3390/genes15010071Test
https://curis.ku.dk/portal/da/publications/cerebrospinal-fluid-c1esterase-inhibitor-andTest-tie1-levels-affect-cognitive-performance(6d47b141-0998-4ad2-89d8-26997fabd675).html
https://curis.ku.dk/ws/files/381679557/genes_15_00071.pdfTest

المؤلفون: Enni Chen, Jiajia Huang, Miao Chen, Jiawei Wu, Puyun Ouyang, Xiaonan Wang, Dingbo Shi, Zhiqiao Liu, Wancui Zhu, Haohui Sun, Shanshan Yang, Baoyu Zhang, Wuguo Deng, Huijuan Qiu, Fangyun Xie

المصدر: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)

مصطلحات موضوعية: FLI1, TIE1, Nasopharyngeal carcinoma (NPC), Radiotherapy resistance, Medicine

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1479-5876Test

الوصول الحر: https://doaj.org/article/225563da46f141b5a39c67b36b1d9c5cTest

المؤلفون: Rajasundaram, Skanda, Zebardast, Nazlee, Mehta, Puja, Khawaja, Anthony P, Warwick, Alasdair, Duchinski, Katherine, Burgess, Stephen, Gill, Dipender, Segrè, Ayellet V, Wiggs, Janey

مصطلحات موضوعية: Colocalization, Intraocular pressure, Mendelian randomization, Primary open-angle glaucoma, TEK, TIE1, Animals, Humans, Glaucoma, Open-Angle, Mendelian Randomization Analysis, Angiopoietins

وصف الملف: text/xml; application/pdf; application/zip

العلاقة: https://www.repository.cam.ac.uk/handle/1810/361673Test

الإتاحة: https://www.repository.cam.ac.uk/handle/1810/361673Test

المؤلفون: Rajasundaram, S, Zebardast, N, Mehta, P, Khawaja, AP, Warwick, A, Duchinski, K, Burgess, S, Gill, D, Segrè, AV, Wiggs, J

المصدر: Journal of Translational Medicine , 21 , Article 847. (2023)

مصطلحات موضوعية: Colocalization, Intraocular pressure, Mendelian randomization, Primary open-angle glaucoma, TEK, TIE1, Animals, Humans, Glaucoma, Open-Angle, Mendelian Randomization Analysis, Angiopoietins

وصف الملف: application/pdf

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10183216/1/s12967-023-04737-9.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10183216Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10183216/1/s12967-023-04737-9.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10183216Test/

المؤلفون: Wei, Yan, Yu, Panpan, Zhao, Zouyu, Sun, Chongfeng, Sun, Qianyu, Bai, Rui, Gao, Weirui, Yang, Ping

المصدر: Exp Cell Res ; ISSN:1090-2422 ; Volume:439 ; Issue:1

مصطلحات موضوعية: Cervical cancer, Clinical prognosis, Epithelial-mesenchymal transition (EMT), Metastasis, PI3K/AKT signaling pathway, Tie1

العلاقة: https://doi.org/10.1016/j.yexcr.2024.114060Test; https://pubmed.ncbi.nlm.nih.gov/38719173Test

الإتاحة: https://doi.org/10.1016/j.yexcr.2024.114060Test
https://pubmed.ncbi.nlm.nih.gov/38719173Test

المؤلفون: Chaojie Li, Nannan Yang, Zhijin Chen, Ning Xia, Qungang Shan, Ziyin Wang, Jian Lu, Mingyi Shang, Zhongmin Wang

المصدر: Cancer Cell International, Vol 21, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Tie1, Hypoxia, Stemness, HIF-1α, Cisplatin resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-2867Test

الوصول الحر: https://doaj.org/article/f1da6a12c77749a8ae98c466542c8ae2Test

المؤلفون: Korhonen, Emilia A., Murtomäki, Aino, Jha, Sawan Kumar, Anisimov, Andrey, Pink, Anne, Zhang, Yan, Stritt, Simon, Liaqat, Inam, Stanczuk, Lukas, Alderfer, Laura, Sun, Zhiliang, Kapiainen, Emmi, Singh, Abhishek, Sultan, Ibrahim, Lantta, Anni, Leppänen, Veli Matti, Eklund, Lauri, He, Yulong, Augustin, Hellmut G., Vaahtomeri, Kari, Saharinen, Pipsa, Makinen, Taija, Alitalo, Kari

المساهمون: CAN-PRO - Translational Cancer Medicine Program, Research Programs Unit, University of Helsinki, Medicum, Michael Jeltsch / Principal Investigator, Cell Communication, Biosciences, Kari Alitalo / Principal Investigator, Molecular and Integrative Biosciences Research Programme, Department of Biochemistry and Developmental Biology, Helsinki In Vivo Animal Imaging Platform (HAIP), HUSLAB, Digital Precision Cancer Medicine (iCAN)

مصطلحات موضوعية: 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology, LYMPHATIC VESSEL DEVELOPMENT, GROWTH-FACTOR-C, PHOSPHATIDYLINOSITOL 3-KINASE, GENE-EXPRESSION, ANGIOPOIETIN 2, RECEPTOR, TIE1, VALVE, ANGIOGENESIS, VASCULATURE

وصف الملف: application/pdf

العلاقة: We thank Riitta Kauppinen, Eleonoora Wihuri, Tapio Tainola, Karri Niiranen, Tanja Laakkonen, Jarmo Koponen, Joel Noutere, Tony Helenius, Jaana Träskelin, and Hanna Seppälä for their expert technical assistance; Mariona Graupera (Josep Carreras Leukaemia Research Institute, Barcelona) for providing Pik3cafl mice; Dieter Saur (Technische Universität München) for the R26-LSL-Pik3caH1047Rmice; and Sagrario Ortega (CNIO, Madrid) for the Vegfr3-CreERT2 mice. We thank Seppo Ylä-Herttuala (A.I. Vir-tanen Institute for Molecular Sciences, Kuopio) for providing Ad vectors; Christer Betsholtz for helpful discussions and comments on the manuscript; and Veijo Salo for assistance with the image analysis. We also thank the Biomedicum Imaging Unit; the Flow Cytometry Unit at the Helsinki Institute of Life Sciences (HiLIFE) at the University of Helsinki; and the Laboratory Animal Centers at HiLIFE; the University of Helsinki and University of Oulu; and the Transgenic and Tissue Phenotyping Core Facility at Biocenter Oulu, supported by the University of Oulu and Biocenter Finland and the Single cell core Facility at Flemingsberg campus (SICOF) at the Karolinska Institute for providing professional services and valuable help. The illustrative graphs in Figure 8A and Supplemental Figure 14A were created using BioRender. This work was funded by the Wihuri Foundation (to KA, EAK, AM, SKJ, AA, VML, IS, PS, and KV); the European Union’s Horizon 2020 Research and Innovation Programme under grant agreements 874708 (THER-ALYMPH, to KA) and 773076 (to PS); the Novo Nordisk Foundation (grant NNF16OC0023554, to KA); the Sigrid Jusélius Foundation (to KA, PS, KV, and LE); the Hospital District of Helsinki and the Uusimaa Research Grant (to KA); the Cancer Foundation Finland (to KA and PS); the Academy of Finland Centre of Excellence Program (307366, to KA); the Academy of Finland Research Costs of Academy Professor (312516, to KA); the Maud Kuistila Memorial Foundation (to EAK); the Ida Montini Foundation (to EAK); The Priority Academic Program Development of Jiangsu Higher Education Institutions (to YH); the National Natural Science Foundation of China (31970768, to YH); the Knut and Alice Wallenberg Foundation (2018.0218, to TM); the Swedish Research Council (2020-02692, to TM); the Academy of Finland (310986, to LE; 310075, to PS); the Academy of Finland Academy Fellow Funding (315710, to KV); and the European Research Council Advanced Grant Angiomature (project 787181, to HGA).; Korhonen , E A , Murtomäki , A , Jha , S K , Anisimov , A , Pink , A , Zhang , Y , Stritt , S , Liaqat , I , Stanczuk , L , Alderfer , L , Sun , Z , Kapiainen , E , Singh , A , Sultan , I , Lantta , A , Leppänen , V M , Eklund , L , He , Y , Augustin , H G , Vaahtomeri , K , Saharinen , P , Makinen , T & Alitalo , K 2022 , ' Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression ' , Journal of Clinical Investigation , vol. 132 , no. 15 , e155478 . https://doi.org/10.1172/JCI155478Test; ORCID: /0000-0001-7829-3518/work/118360664; 85135246300; 038e3928-9aaf-4ee9-9f46-49d90d97068b; http://hdl.handle.net/10138/347702Test; 000842455700004

الإتاحة: http://hdl.handle.net/10138/347702Test

المؤلفون: Leena Tiainen, Emilia A. Korhonen, Veli-Matti Leppänen, Tiina Luukkaala, Mari Hämäläinen, Minna Tanner, Outi Lahdenperä, Pia Vihinen, Arja Jukkola, Peeter Karihtala, Sonja Aho, Eeva Moilanen, Kari Alitalo, Pirkko-Liisa Kellokumpu-Lehtinen

المصدر: BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Tie1, Angiopoietin-2, Angiogenesis, Metastatic breast cancer, Prognostic marker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12885-019-5959-8Test; https://doaj.org/toc/1471-2407Test

الوصول الحر: https://doaj.org/article/cbbf93a5aff24e33b03d163c0d2624fdTest