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المؤلفون: Thomas Ihle Aarhus, Frithjof Bjørnstad, Camilla Wolowczyk, Kristin Uhlving Larsen, Line Rognstad, Trygve Leithaug, Anke Unger, Peter Habenberger, Alexander Wolf, Geir Bjørkøy, Clare Pridans, Jan Eickhoff, Bert Klebl, Bård H. Hoff, Eirik Sundby
المصدر: Aarhus, T I, Bjørnstad, F, Wolowczyk, C, Larsen, K U, Rognstad, L, Leithaug, T, Unger, A, Habenberger, P, Wolf, A, Bjørkøy, G, Pridans, C, Eickhoff, J, Klebl, B, Hoff, B H & Sundby, E 2023, ' Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form ', Journal of Medicinal Chemistry, vol. 66, no. 10, pp. 6959-6980 . https://doi.org/10.1021/acs.jmedchem.3c00428Test
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eadb975b45033dbb1fd91897a1eaf34Test
https://hdl.handle.net/20.500.11820/1b3ebb9b-cf94-456a-948e-bbbf0e0e8792Test -
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المؤلفون: Kristin G. Nørsett, Ann Christin Reiersølmoen, Bård Helge Hoff, Eirik Sundby, Sarah Eckelt, Thomas Ihle Aarhus
المصدر: Bioorganic & Medicinal Chemistry Letters
مصطلحات موضوعية: Substituent, Cancer therapy, Molecular Dynamics Simulation, medicine.disease_cause, 01 natural sciences, Biochemistry, Cross-reactivity, Cell Line, chemistry.chemical_compound, Erlotinib Hydrochloride, Mice, Drug Discovery, medicine, Animals, Pyrroles, Epidermal growth factor receptor, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Binding Sites, biology, 010405 organic chemistry, Kinase, Aryl, Organic Chemistry, 0104 chemical sciences, ErbB Receptors, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Pyrimidines, chemistry, Cancer research, biology.protein, Erlotinib, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d45ff199e21667716bc31044df08faTest
http://hdl.handle.net/11250/2635253Test -
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المصدر: Tetrahedron Letters. 55:5748-5750
مصطلحات موضوعية: Purine, Sodium borohydride, chemistry.chemical_compound, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Michael reaction, Methanol, Alkylation, Purine metabolism, Biochemistry, Medicinal chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::13c62c915978b3336ddcfb6f13f2f37cTest
https://doi.org/10.1016/j.tetlet.2014.08.102Test
