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1دورية أكاديمية
المؤلفون: Jun Liang (251318), Jason R. Zbieg (1892965), Robert A. Blake (8974823), Jae H. Chang (1429789), Stephen Daly (2430460), Antonio G. DiPasquale (1274730), Lori S. Friedman (166879), Thomas Gelzleichter (11113391), Matthew Gill (589302), Jennifer M. Giltnane (11113394), Simon Goodacre (1577413), Jane Guan (166826), Steven J. Hartman (10157036), Ellen Rei Ingalla (8908757), Lorn Kategaya (11113397), James R. Kiefer (1443889), Tracy Kleinheinz (1845637), Sharada S. Labadie (1833826), Tommy Lai (2572615), Jun Li (6494), Jiangpeng Liao (1947631), Zhiguo Liu (594653), Vidhi Mody (8908760), Neville McLean (2128303), Ciara Metcalfe (8908763), Michelle A. Nannini (11113400), Jason Oeh (1845505), Martin G. O’Rourke (11113403), Daniel F. Ortwine (1600621), Yingqing Ran (2100610), Nicholas C. Ray (3064926), Fabien Roussel (3030714), Amy Sambrone (1551289), Deepak Sampath (640340), Leah K. Schutt (11113406), Maia Vinogradova (8908772), John Wai (1503217), Tao Wang (12008), Ingrid E. Wertz (11113409), Jonathan R. White (11113412), Siew Kuen Yeap (1346391), Amy Young (251900), Birong Zhang (1947472), Xiaoping Zheng (566379), Wei Zhou (24328), Yu Zhong (291917), Xiaojing Wang (147040)
مصطلحات موضوعية: Cell Biology, Genetics, Neuroscience, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, Exceptional Preclinical Profile, dose, Bioavailable, human, candidate, combination, liability, Phase, Orally, antagonist, Breast Cancer Breast cancer, wild-type ER α tumor model, GDC -9545, estrogen receptor degrader, antiproliferation, SERD, interaction, Estrogen Receptor Antagonist, giredestrant, Fine-tuning, PDX
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المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602f35b92f38a4e317349755783d4b4eTest
https://doi.org/10.1158/1535-7163.22499713Test -
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المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698324299a1e8945ea2d58c1c0bc79a7Test
https://doi.org/10.1158/1535-7163.22499716.v1Test -
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المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4f35c13437b18b0d84db54fef4380a6dTest
https://doi.org/10.1158/1535-7163.c.6536236Test -
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المؤلفون: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Male, 0301 basic medicine, obesity, Medical Sciences, FGF21, Adipose tissue, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Multidisciplinary, biology, Middle Aged, Biological Sciences, Adipose Tissue, Female, Adiponectin, Antibody, medicine.symptom, FGF21 receptor activation, Adult, Agonist, medicine.medical_specialty, Adolescent, medicine.drug_class, 030209 endocrinology & metabolism, Antibodies, Food Preferences, Young Adult, 03 medical and health sciences, Internal medicine, Weight Loss, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Aged, business.industry, Fibroblast growth factor receptor 1, Body Weight, medicine.disease, Obesity, Fibroblast Growth Factors, stomatognathic diseases, Macaca fascicularis, 030104 developmental biology, Endocrinology, biology.protein, food preference, business, metabolism, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18Test
https://doi.org/10.1073/pnas.2012073117Test -
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المؤلفون: Martin O'Rourke, Nicholas Charles Ray, Thomas Gelzleichter, Leah Schutt, Ellen Ingalla, Neville James Mclean, Xiaojing Wang, Stephen Daly, Yingqing Ran, Jiangpeng Liao, Tommy Lai, Yu Zhong, Jun Liang, Sharada Labadie, Lori Friedman, Amy Sambrone, Jun Li, Robert A. Blake, Tao Wang, Liu Zhiguo, Birong Zhang, Steven J. Hartman, Jae H. Chang, Wei Zhou, Jane Guan, Vidhi Mody, Jonathan White, Fabien Roussel, Antonio G. DiPasquale, Jason R. Zbieg, Daniel F. Ortwine, Amy Young, James R. Kiefer, Maia Vinogradova, Simon Charles Goodacre, Deepak Sampath, Tracy Kleinheinz, Xiaoping Zheng, Jennifer M. Giltnane, Lorn Kategaya, Ingrid E. Wertz, Matthew Gill, Ciara Metcalfe, Siew Kuen Yeap, John S. Wai, Jason Oeh, Michelle Nannini
المصدر: Journal of medicinal chemistry. 64(16)
مصطلحات موضوعية: Phases of clinical research, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Mice, Structure-Activity Relationship, Breast cancer, Dogs, In vivo, Drug Discovery, medicine, Animals, Humans, Dosing, Molecular Structure, Chemistry, Antagonist, Estrogen Receptor alpha, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, Macaca fascicularis, Cell culture, Cancer research, MCF-7 Cells, Molecular Medicine, Female, Estrogen Receptor Antagonists, Carbolines
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee86fe3f8068fbb2ff9647a59eadb710Test
https://pubmed.ncbi.nlm.nih.gov/34251202Test -
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المؤلفون: Sharmila Rajan, Thomas Gelzleichter, Amos Baruch, Junichiro Sonoda, C. Andrew Boswell, Dale Stevens, Eric Stefanich, Danielle Mandikian, Kyra J. Cowan
المصدر: mAbs. 9:1379-1388
مصطلحات موضوعية: Male, 0301 basic medicine, Receptor complex, FGF21, medicine.drug_class, Receptor expression, Immunology, Drug Evaluation, Preclinical, Adipose tissue, CHO Cells, Pharmacology, Biology, Diet, High-Fat, Monoclonal antibody, 03 medical and health sciences, Cricetulus, Report, Cricetinae, medicine, Animals, Immunology and Allergy, Tissue Distribution, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Adiponectin, Fibroblast growth factor receptor 1, Antibodies, Monoclonal, Fibroblast Growth Factors, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Adipose Tissue, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe09bafc48ef65e54437fd42a8236afTest
https://doi.org/10.1080/19420862.2017.1373923Test -
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المؤلفون: Gerhard F. Weinbauer, Akihiro Arima, Chris Schuetz, Cynthia Woods, Hong Wang, Jane L. Grogan, Thomas Gelzleichter, Yutaka Chihaya, Gary Cain, Gunnar Habermann, Jim Xiao
المصدر: Reproductive Toxicology. 63:82-95
مصطلحات موضوعية: Male, 0301 basic medicine, Lymphocyte, Embryonic Development, Lymphocytosis, Antibodies, Monoclonal, Humanized, Toxicology, Immunoglobulin G, Fetal Development, Andrology, 03 medical and health sciences, Pregnancy, medicine, Animals, Mesenteric lymph nodes, Lymphotoxin-alpha, Maternal-Fetal Exchange, Lymph node, Pateclizumab, Fetus, biology, Embryo, Mammalian, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, Immunology, biology.protein, Female, Lymph Nodes, Lymph, Antibody, Dendritic Cells, Follicular
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a2e69ba3906a3b5f46dd8a6489dc72Test
https://doi.org/10.1016/j.reprotox.2016.05.014Test -
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المؤلفون: Susan L. Limb, Lin Pan, Linda Nguyen, Yuan Chen, Thomas Gelzleichter, Cindy Burg
المصدر: Pulmonary pharmacologytherapeutics. 51
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Time Factors, Pyridones, Cmax, Administration, Oral, 030204 cardiovascular system & hematology, Gastroenterology, Drug Administration Schedule, Rats, Sprague-Dawley, 03 medical and health sciences, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Pharmacokinetics, Oral administration, Internal medicine, medicine, Animals, Pharmacology (medical), Gastric emptying, business.industry, Stomach, digestive, oral, and skin physiology, Biochemistry (medical), Anti-Inflammatory Agents, Non-Steroidal, Pirfenidone, medicine.disease, Rats, medicine.anatomical_structure, 030228 respiratory system, Tolerability, Gastric Emptying, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fadbac9bf93b56c393cf4fd4780449Test
https://pubmed.ncbi.nlm.nih.gov/29944949Test -
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المؤلفون: Kyra J. Cowan, Feng Yang, Mark Z. Chen, Ambrose Williams, Terry Hudson, Shannon Liu, Nicole Valle, Timothy Tully, Junichiro Sonoda, Thomas Gelzleichter, Sharmila Rajan, Frank Macchi
المصدر: Journal of pharmacological and toxicological methods. 94(Pt 1)
مصطلحات موضوعية: 0301 basic medicine, Male, Bispecific antibody, Receptor complex, Mice, Obese, CHO Cells, Toxicology, Antibodies, Cell Line, 03 medical and health sciences, Mice, Cricetulus, Animals, Humans, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Related impurities, Obese Mice, Pharmacology, Manufacturing process, Chemistry, Membrane Proteins, Highly selective, Combinatorial chemistry, Mice, Inbred C57BL, Molecular Weight, stomatognathic diseases, Disease Models, Animal, Drug Combinations, 030104 developmental biology, HEK293 Cells, Product (mathematics), Immunoglobulin G, Drug product, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b66987db00744fc1e7acdc79bb85f9Test
https://pubmed.ncbi.nlm.nih.gov/29660397Test