المؤلفون: Loesche, Christian, Picard, Damien, Van Hoorick, Benjamin, Schuhmann, Imelda, Jäger, Petra, Klein, Kai, Schuhler, Carole, Thoma, Gebhard, Markert, Christian, Poller, Birk, Zamurovic, Natasa, Weiss, H. Markus, Otto, Heike, Fink, Martin, Röhn, Till A.

المصدر: Clinical and Translational Science ; volume 17, issue 2 ; ISSN 1752-8054 1752-8062

الإتاحة: https://doi.org/10.1111/cts.13724Test

المؤلفون: Hacini‐Rachinel, Feriel, Hauchard, Alice, Bruno, Sandro, Paulat, Guido, Cojean, Celine, Loesle, Perrine, Schneider, Martin Alexander, Bourne, Marta, Elain, Gaelle, Roth, Lukas, Urban, Beatrice, Viebrock, Sabine, Leon, Anette Orjuela, Roehn, Till A., Loesche, Christian, Werfel, Thomas, Thoma, Gebhard, Zerwes, Hans‐Günter

المصدر: Experimental Dermatology; May2024, Vol. 33 Issue 5, p1-9, 9p

مصطلحات موضوعية: ATOPIC dermatitis, TOPICAL drug administration, PLASTIC surgery, SKIN diseases, STAT proteins

المؤلفون: Thoma, Gebhard, Miltz, Wolfgang, Srinivas, Honnappa, Penno, Carlos, Kiffe, Michael, Gajewska, Monika, Klein, Kai, Evans, Amanda, Beerli, Christian, Roehn, Till

العلاقة: Thoma, Gebhard, Miltz, Wolfgang, Srinivas, Honnappa, Penno, Carlos, Kiffe, Michael, Gajewska, Monika, Klein, Kai, Evans, Amanda, Beerli, Christian and Roehn, Till (2024) Structure Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. Journal of medicinal chemistry.

الإتاحة: https://doi.org/10.1021/acs.jmedchem.4c00290Test
https://oak.novartis.com/53009Test/

المؤلفون: Thoma, Gebhard, Markert, Christian, Lueoend, Rainer, Miltz, Wolfgang, Spanka, Carsten, Bollbuck, Birgit, Wolf, Romain M., Srinivas, Honnappa, Penno, Carlos A., Kiffe, Michael, Gajewska, Monika, Bednarczyk, Dallas, Wieczorek, Grazyna, Evans, Amanda, Beerli, Christian, Röhn, Till A.

المصدر: Journal of Medicinal Chemistry; 12/14/2023, Vol. 66 Issue 23, p16410-16425, 16p

المؤلفون: Thoma, Gebhard, Decoret, Odile, Vangrevelinghe, Eric, Trunzer, Markus, Decker, Andrea, Orjuela Leon, Anette, Beerli, Christian, Bruno, Sandro, Hauchard, Alice, Paulat, Guido, Zerwes, Hans-Guenter, Hacini-Rachinel, Feriel

المصدر: Journal of Medicinal Chemistry; 11/9/2023, Vol. 66 Issue 21, p15042-15053, 12p

المؤلفون: Thoma, Gebhard, Decoret, Odile, Vangrevelinghe, Eric, Trunzer, Markus, Decker, Andrea, Bruno, Sandro, Hauchard, Alice, Hacini-Rachinel, Feriel

العلاقة: Thoma, Gebhard, Decoret, Odile, Vangrevelinghe, Eric, Trunzer, Markus, Decker, Andrea, Bruno, Sandro, Hauchard, Alice and Hacini-Rachinel, Feriel (2023) Design of a Super-Soft Topical JAK Inhibitor, which Is Efficacious in Human Skin but Rapidly Deactivated in Blood. Journal of medicinal chemistry, 66. pp. 15042-15053.

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01735Test
https://oak.novartis.com/51818Test/
https://pubs.acs.org/journal/jmcmarTest

المؤلفون: Thoma, Gebhard, Duthaler, Rudolf, Waelchli, Rudolf, Hauchard, Alice, Bruno, Sandro, Strittmatter-Keller, Ulrike, Viebrock, Sabine, Aichholz, Reiner, Beltz, Karen, Grove, Kerri, Hoque, Shaila, Rudewicz, Patrick, Zerwes, Hans Guenter

العلاقة: Thoma, Gebhard, Duthaler, Rudolf, Waelchli, Rudolf, Hauchard, Alice, Bruno, Sandro, Strittmatter-Keller, Ulrike, Viebrock, Sabine, Aichholz, Reiner, Beltz, Karen, Grove, Kerri, Hoque, Shaila, Rudewicz, Patrick and Zerwes, Hans Guenter (2023) Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic Dermatitis. Journal of medicinal chemistry. ISSN 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.2c01977Test
https://oak.novartis.com/49093Test/

المؤلفون: Thoma, Gebhard, Vangrevelinghe, Eric, Luneau, Alexandre, Piechon, Philippe, Beerli, Christian, Zerwes, Hans Guenter

العلاقة: Thoma, Gebhard, Vangrevelinghe, Eric, Luneau, Alexandre, Piechon, Philippe, Beerli, Christian and Zerwes, Hans Guenter (2023) Novel Concept for Super-Soft Topical Drugs: Deactivation by an Enzyme-Induced Switch into an Inactive Conformation. ACS medicinal chemistry letters, 14. ISSN 1948-5875; https://doi.org/10.1021/acsmedchemlett.3c00169Test

الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00169Test
https://oak.novartis.com/50267Test/

المؤلفون: Thoma, Gebhard, Veenstra, Siem, Strang, Ross, Blanz, Joachim, Vangrevelinghe, Eric, Berghausen, Jörg, Lee, Christian C., Zerwes, Hans-Günter

وصف الملف: application/pdf

العلاقة: http://www.osti.gov/servlets/purl/1250393Test; https://www.osti.gov/biblio/1250393Test; https://doi.org/10.1016/j.bmcl.2015.08.037Test

الإتاحة: https://doi.org/10.1016/j.bmcl.2015.08.037Test
http://www.osti.gov/servlets/purl/1250393Test
https://www.osti.gov/biblio/1250393Test