نتائج البحث - "Therapeutic Index, Drug"

المصدر: Oncogene
Crawford, L J, Campbell, D C, Morgan, J J, Lawson, M A, Down, J M, Chauhan, D, McAvera, R M, Morris, T C, Hamilton, C, Krishnan, A, Rajalingam, K, Chantry, A D & Irvine, A E 2020, ' The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in Multiple Myeloma ', Oncogene, vol. 39, pp. 5001–5014 . https://doi.org/10.1038/s41388-020-1345-xTest

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Ubiquitylation, Cell Survival, Ubiquitin-Protein Ligases, Myeloma, Antineoplastic Agents, Bone Marrow Cells, Mice, SCID, Article, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Ubiquitin, Mice, Inbred NOD, Cell Line, Tumor, Genetics, medicine, Animals, Humans, RNA, Small Interfering, Molecular Biology, Lenalidomide, Cell Proliferation, Gene knockdown, biology, Oncogene, Cell growth, Tumor Suppressor Proteins, Ubiquitination, Cell Cycle Checkpoints, Ubiquitin ligase, Therapeutic Index, Drug, 030104 developmental biology, medicine.anatomical_structure, chemistry, Proteasome, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, RNA Interference, Bone marrow, Growth inhibition, Multiple Myeloma, Oligopeptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37220f16bcd269c548b5b079bcc895e5Test
http://europepmc.org/articles/PMC7329634Test

6

A Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union

المؤلفون: Rita Bento Guerreiro, Nuno Silva, Luís F. Gouveia, Milton Bonelli, Paulo Paixão, Kevin Blake, Alfredo Garcia Arieta, José A.G. Morais

المصدر: Clinical pharmacology and therapeutics. 111(2)

مصطلحات موضوعية: Drug, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, Drug Compounding, Population, Cmax, Bioequivalence, Models, Biological, Tacrolimus, Statistics, media_common.cataloged_instance, Medicine, Humans, Pharmacology (medical), Computer Simulation, European Union, Everolimus, Treatment Failure, European union, education, Drug Approval, media_common, Pharmacology, education.field_of_study, Biological Variation, Individual, Dose-Response Relationship, Drug, business.industry, Confidence interval, Europe, Therapeutic Index, Drug, Thyroxine, Therapeutic Equivalency, Sample size determination, Research Design, Sample Size, Cyclosporine, Geometric mean, business, Colchicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c1863d394eedbd3d3c8042592f2daaTest
https://pubmed.ncbi.nlm.nih.gov/34657284Test

7

Nano optical and electrochemical sensors and biosensors for detection of narrow therapeutic index drugs

المؤلفون: Reza Mahjub, Mahdi Jamshidi, Katayoun Derakhshandeh, Akram Ranjbar, Omid Heydari Shayesteh

المصدر: Mikrochimica acta. 188(12)

مصطلحات موضوعية: Materials science, High interest, technology, industry, and agriculture, Nanotechnology, Biosensing Techniques, Electrochemical Techniques, Quantitative determination, Analytical Chemistry, Therapeutic Index, Drug, Therapeutic index, Pharmaceutical Preparations, Nano, Humans, Biosensor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04bda9d97c4e4a9bce36301966197eaTest
https://pubmed.ncbi.nlm.nih.gov/34741213Test

8

Proactive Vs Reactive Therapeutic Drug Monitoring of Infliximab in Crohn’s Disease: A Cost-Effectiveness Analysis in a Simulated Cohort

المؤلفون: Bonnie Baumgartner, Konstantinos Papamichael, Mark T. Osterman, Diana M. Negoescu, Adam S. Cheifetz, Byron P. Vaughn, Brooke Swanhorst, James P. Campbell, Eva A. Enns

المصدر: Inflammatory Bowel Diseases. 26:103-111

مصطلحات موضوعية: medicine.medical_specialty, Cost effectiveness, Cost-Benefit Analysis, Population, Inflammatory bowel disease, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Crohn Disease, Gastrointestinal Agents, Internal medicine, medicine, Humans, Immunology and Allergy, Computer Simulation, education, health care economics and organizations, education.field_of_study, Crohn's disease, medicine.diagnostic_test, business.industry, Gastroenterology, Cost-effectiveness analysis, medicine.disease, Infliximab, Therapeutic Index, Drug, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Cohort, 030211 gastroenterology & hepatology, Quality-Adjusted Life Years, Drug Monitoring, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c185d6fa13b944ef20ffc61c73894aa4Test
https://doi.org/10.1093/ibd/izz113Test

9

Repurposing disulfiram for treatment of Staphylococcus aureus infections

المؤلفون: Ritesh P. Thakare, Arunava Dasgupta, Grace Kaul, Sidharth Chopra, Manjulika Shukla

المصدر: International Journal of Antimicrobial Agents. 53:709-715

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cabdcb1a0efa37c5e084effe96f6f60Test
https://doi.org/10.1016/j.ijantimicag.2019.03.024Test

10

Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents

المؤلفون: Jason A. Roberts, Joseph F. Standing, Anouk E. Muller, Maya Hites, Sonia Luque, Jennifer Le, João Paulo Telles, Roger J. M. Brüggemann, Michael Thy, Pieter De Cock, Birgit C. P. Koch, David L. Paterson, Kristina Nadrah, Markus Zeitlinger, Alasdair P. MacGowan, Timothy Felton, Deborah Marriott, Michael Wölfl-Duchek

المساهمون: Pharmacy, Medical Microbiology & Infectious Diseases

المصدر: Clinical Pharmacokinetics
PK/PD of Anti-Infectives Study Group (EPASG) of the European Society of Clinical Microbiology, Infectious Diseases (ESCMID) 2020, ' Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures : A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents ', Clinical Pharmacokinetics, vol. 59, no. 10, pp. 1195-1216 . https://doi.org/10.1007/s40262-020-00924-9Test
Clinical Pharmacokinetics, 59, 1195-1216
Clinical pharmacokinetics
Clinical Pharmacokinetics, 59, 10, pp. 1195-1216
Clinical Pharmacokinetics, 59(10), 1195-1216. Adis

مصطلحات موضوعية: 0301 basic medicine, Review Article, Pharmacologie, Pharmacology, chemistry.chemical_compound, 0302 clinical medicine, COVID-19 (Malaltia) -- Tractament, Medicine, Hypnotics and Sedatives, Pharmacology (medical), Drug Interactions, 030212 general & internal medicine, Medicaments antivírics, Antiviral Agents/pharmacokinetics, media_common, Analgesics, virus diseases, Lopinavir, Renal Replacement Therapy, Coronavirus Infections, medicine.drug, Drug, Extracorporeal Membrane Oxygenation/methods, media_common.quotation_subject, 030106 microbiology, Pneumonia, Viral, Analgesics/pharmacology, Favipiravir, Antiviral Agents, Hypnotics and Sedatives/pharmacology, 03 medical and health sciences, Betacoronavirus, Pharmacotherapy, Renal Replacement Therapy/methods, Extracorporeal Membrane Oxygenation, Pharmacokinetics, Intensive care, Humans, Anticoagulants/pharmacology, Pandemics, PK/PD models, Dose-Response Relationship, Drug, business.industry, SARS-CoV-2, Ribavirin, Anticoagulants, COVID-19, Coronavirus Infections/drug therapy, Pneumonia, Viral/drug therapy, Medicaments -- Administració, Clinical trial, Therapeutic Index, Drug, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], chemistry, Pharmacodynamics, Ritonavir, business

وصف الملف: application/pdf; 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bd8eb0e20ea2e71117853a3bed5e01Test
https://pubmed.ncbi.nlm.nih.gov/32725382Test

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