المؤلفون: Radoslav Savić, Jialiang Yang, Simon Koplev, Mahru C. An, Priyanka L. Patel, Robert N. O’Brien, Brittany N. Dubose, Tetyana Dodatko, Eduard Rogatsky, Katyayani Sukhavasi, Raili Ermel, Arno Ruusalepp, Sander M. Houten, Jason C. Kovacic, Andrew F. Stewart, Christopher B. Yohn, Eric E. Schadt, Remi-Martin Laberge, Johan L.M. Björkegren, Zhidong Tu, Carmen Argmann

المصدر: Cell Reports, Vol 42, Iss 11, Pp 113371- (2023)

مصطلحات موضوعية: CP: Cell biology, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124723013839Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/1c20f6d542d54b86acc9526737df22b2Test

المؤلفون: Lauren A. Peters, Joshua R. Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Tetyana Dodatko, Mariana P. Amaro, Paula Restrepo, Zhi Chai, J. Rodrigo Mora, Holly A. Raymond, Mark Curran, Radu Dobrin, Anuk Das, Huabao Xiong, Eric E. Schadt, Carmen Argmann, Bojan Losic

المصدر: Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2399-3642Test

الوصول الحر: https://doaj.org/article/95a2a99b4f784d3c91deb9675e5c43a3Test

المؤلفون: João Leandro, Susmita Khamrui, Chalada Suebsuwong, Peng-Jen Chen, Cody Secor, Tetyana Dodatko, Chunli Yu, Roberto Sanchez, Robert J. DeVita, Sander M. Houten, Michael B. Lazarus

المصدر: Open Biology, Vol 12, Iss 9 (2022)

مصطلحات موضوعية: crystal structure, glutaric aciduria, inborn errors of metabolism, lysine metabolism, enzymology, assay development, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2046-2441Test

الوصول الحر: https://doaj.org/article/5d1f92da3b604957856043910867cf16Test

المؤلفون: Tetyana Dodatko, Monique Akoachere, Stefan M Muehlbauer, Forrest Helfrich, Amber Howerton, Christian Ross, Vicki Wysocki, Jürgen Brojatsch, Ernesto Abel-Santos

المصدر: PLoS ONE, Vol 4, Iss 7, p e6398 (2009)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC2712684?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/5c682a53299c4d13bfb76ab5bc613690Test

المؤلفون: João Leandro, Susmita Khamrui, Chalada Suebsuwong, Peng-Jen Chen, Cody Secor, Tetyana Dodatko, Chunli Yu, Roberto Sanchez, Robert J. DeVita, Sander M. Houten, Michael B. Lazarus

مصطلحات موضوعية: Biochemistry, Cell Biology, Developmental Biology, Structural Biology, crystal structure, glutaric aciduria, inborn errors of metabolism, lysine metabolism, enzymology, assay development

العلاقة: https://figshare.com/articles/journal_contribution/Supplementary_Information_from_Characterization_and_structure_of_the_human_lysine-2-oxoglutarate_reductase_domain_a_novel_therapeutic_target_for_treatment_of_glutaric_aciduria_type_1/21030849Test

الإتاحة: https://doi.org/10.6084/m9.figshare.21030849.v1Test
https://figshare.com/articles/journal_contribution/Supplementary_Information_from_Characterization_and_structure_of_the_human_lysine-2-oxoglutarate_reductase_domain_a_novel_therapeutic_target_for_treatment_of_glutaric_aciduria_type_1/21030849Test

المؤلفون: Sander M. Houten, Tetyana Dodatko, William Dwyer, Hongjie Chen, Brandon Stauffer, Robert J. DeVita, Frédéric M. Vaz, Chunli Yu, João Leandro

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::155c7ef83a0ddb32aed7b9feba155142Test
https://doi.org/10.1101/2022.11.22.517273Test

المؤلفون: null João Leandro, null Susmita Khamrui, null Chalada Suebsuwong, null Peng-Jen Chen, null Cody Secor, null Tetyana Dodatko, null Chunli Yu, null Roberto Sanchez, null Robert J. DeVita, null Sander M. Houten, null Michael B. Lazarus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2821e2ece457ef1b68e245110f6536c7Test
https://doi.org/10.1098/rsob.220179/v3/response1Test

المؤلفون: Sander M. Houten, Tetyana Dodatko, Brandon Stauffer, Chunli Yu, Hongjie Chen, João Leandro, Robert J. DeVita

المصدر: Journal of Inherited Metabolic Disease. 43:1154-1164

مصطلحات موضوعية: Male, Metabolite, Lysine, Dehydrogenase, Glutaric aciduria type 1, Glutaric acid, Glutarates, Mice, 03 medical and health sciences, chemistry.chemical_compound, Genetics, medicine, Animals, Humans, Amino Acid Metabolism, Inborn Errors, Genetics (clinical), 030304 developmental biology, Mice, Knockout, 0303 health sciences, Glutaryl-CoA Dehydrogenase, ATP synthase, biology, Brain Diseases, Metabolic, 030305 genetics & heredity, Glutaric aciduria, Brain, medicine.disease, Disease Models, Animal, HEK293 Cells, Liver, chemistry, Biochemistry, Saccharopine, biology.protein, Female, CRISPR-Cas Systems, 2-Aminoadipic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8cc9c66d36f95be4572fc8983f1a21Test
https://doi.org/10.1002/jimd.12276Test

المؤلفون: Natalia S. Nemeria, Frank Jordan, Chunli Yu, Xu Zhang, Sander M. Houten, Robert J. DeVita, Ronald C. Hendrickson, João Leandro, Jan Aten, Tetyana Dodatko, Roberto Sanchez

المساهمون: Pathology, Biomedical Engineering and Physics, Graduate School, ACS - Atherosclerosis & ischemic syndromes

المصدر: Leandro, J, Dodatko, T, Aten, J, Nemeria, N S, Zhang, X, Jordan, F, Hendrickson, R C, Sanchez, R, Yu, C, DeVita, R J & Houten, S M 2020, ' DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo ', Human Molecular Genetics, vol. 29, no. 7, pp. 1168-1179 . https://doi.org/10.1093/HMG/DDAA037Test
Human molecular genetics, 29(7), 1168-1179. Oxford University Press
Hum Mol Genet
Human Molecular Genetics, 29(7), 1168-1179. Oxford University Press

مصطلحات موضوعية: Coenzyme A, Dehydrogenase, Biology, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Oxidoreductase, Genetics, Humans, DHTKD1, Ketoglutarate Dehydrogenase Complex, Amino Acid Metabolism, Inborn Errors, Molecular Biology, Cells, Cultured, Genetics (clinical), 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Dihydrolipoamide dehydrogenase, Glutaryl-CoA Dehydrogenase, Brain Diseases, Metabolic, Ketone Oxidoreductases, General Medicine, General Article One, HEK293 Cells, Biochemistry, chemistry, OGDH, Acyl Coenzyme A, Oxoglutarate dehydrogenase complex, 030217 neurology & neurosurgery, Glutaric Acidemia Type 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b211cbfed828d5e97d2e00a37a3975Test
https://doi.org/10.1093/hmg/ddaa037Test

المؤلفون: João Leandro, Susmita Khamrui, Chalada Suebsuwong, Peng-Jen Chen, Cody Secor, Tetyana Dodatko, Chunli Yu, Roberto Sanchez, Robert J. DeVita, Sander M. Houten, Michael B. Lazarus

مصطلحات موضوعية: Biochemistry, Cell Biology, Developmental Biology, Structural Biology, crystal structure, glutaric aciduria, inborn errors of metabolism, lysine metabolism, enzymology, assay development

العلاقة: https://figshare.com/articles/dataset/Table_S2_from_Characterization_and_structure_of_the_human_lysine-2-oxoglutarate_reductase_domain_a_novel_therapeutic_target_for_treatment_of_glutaric_aciduria_type_1/21153602Test

الإتاحة: https://doi.org/10.6084/m9.figshare.21153602.v1Test
https://figshare.com/articles/dataset/Table_S2_from_Characterization_and_structure_of_the_human_lysine-2-oxoglutarate_reductase_domain_a_novel_therapeutic_target_for_treatment_of_glutaric_aciduria_type_1/21153602Test