المؤلفون: Tan, Justin L, Fogley, Rachel D, Flynn, Ryan A, Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi Peng, T., Brian, Laga, Alvaro C, Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B, Kim, Yoon Jung, Clohessy, John G, Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E, van Rooijen, Ellen, Hagedorn, Elliott J, Shyh-Chang, Ng, White, Richard M, Price, David H, Pandolfi, Pier Paolo, Peterlin, B Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M, Chang, Howard Y, Young, Richard A, Zon, Leonard I

المصدر: Molecular Cell. 62(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, Oncology and Carcinogenesis, Biotechnology, Cancer, Genetics, Aetiology, 2.1 Biological and endogenous factors, Animals, Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Humans, Melanoma, Melanoma, Experimental, Oncogene Proteins, Positive Transcriptional Elongation Factor B, Pyrimidines, RNA-Binding Proteins, Transcription Factors, Transcription, Genetic, Tumor Suppressor Proteins, Zebrafish, Zebrafish Proteins, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/05k7h255Test

المؤلفون: Tenen, Daniel G, Chai, Li, Tan, Justin L

المساهمون: Genome Institute of Singapore Innovation Fellow Award, Agency for Science, Technology, and Research A*ccelerate Gap Award, Singapore Ministry of Health's National Medical Research Council Singapore Translational Research, Singapore Ministry of Education, Research Centres of Excellence initiative, National Institutes of Health, National Heart, Lung, and Blood Institute, Xiu Research Fund

المصدر: Gastroenterology Report ; volume 9, issue 1, page 1-13 ; ISSN 2052-0034

الإتاحة: https://doi.org/10.1093/gastro/goaa066Test
http://academic.oup.com/gastro/article-pdf/9/1/1/36618291/goaa066.pdfTest

المؤلفون: Sun, Wendi, Dai, Lingyun, Yu, Han, Puspita, Brenda, Zhao, Tianyun, Li, Feng, Tan, Justin L., Lim, Yan Ting, Chen, Ming Wei, Sobota, Radoslaw M., Tenen, Daniel G., Prabhu, Nayana, Nordlund, Pär

المساهمون: School of Biological Sciences

مصطلحات موضوعية: DRNTU::Science::Biological sciences, Reactive Oxygen Species, Cellular Thermal Shift Assay

وصف الملف: 14 p.; application/pdf

العلاقة: Redox Biology; Sun, W., Dai, L., Yu, H., Puspita, B., Zhao, T., Li, F., . . . Nordlund, P. (2019). Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA. Redox Biology, 24, 101168-. doi:10.1016/j.redox.2019.101168; https://hdl.handle.net/10356/95947Test; http://hdl.handle.net/10220/49460Test

الإتاحة: https://doi.org/10.1016/j.redox.2019.101168Test
https://hdl.handle.net/10356/95947Test
http://hdl.handle.net/10220/49460Test

المؤلفون: Tan, Justin L., Li, Feng, Yeo, Joanna Z., Yong, Kol Jia, Bassal, Mahmoud A., Ng, Guo Hao, Lee, May Yin, Leong, Chung Yan, Tan, Hong Kee, Wu, Chan-shuo, Liu, Bee Hui, Chan, Tim H., Tan, Zi Hui, Chan, Yun Shen, Wang, Siyu, Lim, Zhi Han, Toh, Tan Boon, Hooi, Lissa, Low, Kia Ngee, Ma, Siming, Kong, Nikki R., Stein, Alicia J., Wu, Yue, Thangavelu, Matan T., Suzuki, Atsushi, Periyasamy, Giridharan, Asara, John M., Dan, Yock Young, Bonney, Glenn K., Chow, Edward K., Lu, Guo-Dong, Ng, Huck Hui, Kanagasundaram, Yoganathan, Ng, Siew Bee, Tam, Wai Leong, Tenen, Daniel G., Chai, Li

المساهمون: Leukemia and Lymphoma Society, Japan Society for the Promotion of Science, Agency for Science, Technology and Research, Genome Institute of Singapore, National Medical Research Council, National Institutes of Health, Ministry of Health -Singapore, National Heart, Lung, and Blood Institute, National Research Foundation Singapore, National Cancer Institute, Ministry of Education - Singapore

المصدر: Gastroenterology ; volume 157, issue 6, page 1615-1629.e17 ; ISSN 0016-5085

مصطلحات موضوعية: Gastroenterology, Hepatology

الإتاحة: https://doi.org/10.1053/j.gastro.2019.08.022Test
https://api.elsevier.com/content/article/PII:S0016508519412420?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0016508519412420?httpAccept=text/plainTest

المؤلفون: Kaufman, Charles K., Mosimann, Christian, Fan, Zi Peng, Yang, Song, Thomas, Andrew J., Ablain, Julien, Tan, Justin L., Fogley, Rachel D., van Rooijen, Ellen, Hagedorn, Elliott J., Ciarlo, Christie, White, Richard M., Matos, Dominick A., Puller, Ann-Christin, Santoriello, Cristina, Liao, Eric C., Young, Richard A., Zon, Leonard I.

المصدر: Science, 2016 Jan . 351(6272), 464-464.

الوصول الحر: http://www.jstor.org/stable/24741537Test

المؤلفون: Tan, Justin L., Fogley, Rachel D., Flynn, Ryan A., Ablain, Julien, Yang, Song, Do, Brian T., Laga, Alvaro C., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B., Kim, Yoon Jung, Clohessy, John G., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E., van Rooijen, Ellen, Hagedorn, Elliott J., Shyh-Chang, Ng, White, Richard M., Price, David H., Pandolfi, Pier Paolo, Peterlin, B. Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M., Chang, Howard Y., Zon, Leonard I., Saint-André, Violaine, Fan, Zi Peng, Young, Richard A.

المساهمون: Massachusetts Institute of Technology. Department of Biology, Saint-André, Violaine, Fan, Zi Peng, Young, Richard A

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/J.MOLCEL.2016.03.013Test; Molecular Cell; http://hdl.handle.net/1721.1/116990Test; Tan, Justin L. et al. “Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.” Molecular Cell 62, 1 (April 2016): 34–46 © 2016 Elsevier Inc; orcid:0000-0001-8855-8647

الإتاحة: https://doi.org/10.1016/J.MOLCEL.2016.03.013Test
http://hdl.handle.net/1721.1/116990Test

المؤلفون: Tenen, Daniel G., Chai, Li, Tan, Justin L.

المساهمون: DEPT OF MEDICINE, CANCER SCIENCE INSTITUTE OF SINGAPORE

المصدر: Scopus OA2021

مصطلحات موضوعية: hepatocellular carcinoma (HCC), metabolic vulnerability, metabolism, targeted therapy

العلاقة: Tenen, Daniel G., Chai, Li, Tan, Justin L. (2020-11-18). Metabolic alterations and vulnerabilities in hepatocellular carcinoma. Gastroenterology Report 9 (1) : 1-13. ScholarBank@NUS Repository. https://doi.org/10.1093/gastro/goaa066Test; https://scholarbank.nus.edu.sg/handle/10635/232866Test

الإتاحة: https://doi.org/10.1093/gastro/goaa066Test
https://scholarbank.nus.edu.sg/handle/10635/232866Test

المؤلفون: Tenen, Daniel G, Chai, Li, Tan, Justin L

المصدر: Gastroenterology Report; Jan2021, Vol. 9 Issue 1, p1-13, 13p

مصطلحات موضوعية: HEPATOCELLULAR carcinoma, CANCER diagnosis, CANCER treatment

المؤلفون: Vu, Kim Anh L., Kumari, Kalpana, Liu, Bee Hui, Gao, Chong, Li, Feng, Tang, Jing Ping, Maddalo, Danilo, Tian, Xi, Liu, Miao, Bassal, Mahmoud Adel, Moein, Shiva, Iakovleva, Viktoriia, Tan, Justin L., Stein, Alicia J., Zhou, Qiling, Fischer, Patrick D., Sigua, Logan H., Qi, Jun, Arthanari, Haribabu, Tenen, Daniel G., Chai, Li

المصدر: Blood; November 2023, Vol. 142 Issue: 1, Number 1 Supplement 1 p7144-7144, 1p

المؤلفون: Tan, Justin l., Fogley, Rachel d., Flynn, Ryan a., Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi peng, Do, Brian t., Laga, Alvaro c., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste b., Kim, Yoon jung, Clohessy, John g., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John e., Van rooijen, Ellen, Hagedorn, Elliott j., Shyh-Chang, Ng, White, Richard m., Price, David h., Pandolfi, Pier paolo, Peterlin, B. matija, Zhou, Yi, Kim, Tae-Hoon, Asara, John m., Chang, Howard y., Young, Richard a., Zon, Leonard i.

المساهمون: Harvard Stem Cell Institute Cambridge, USA (HSCI), Harvard University, Howard Hughes Medical Institute Boston (HHMI), Howard Hughes Medical Institute (HHMI)-Harvard Medical School Boston (HMS), Boston Children's Hospital, Harvard Medical School Boston (HMS), Dana-Farber Cancer Institute Boston, Center for Personal Dynamic Regulomes Stanford (CPDR), Stanford Medicine, Stanford University-Stanford University, Whitehead Institute, Massachusetts Institute of Technology (MIT), Department of Biology MIT Cambridge, USA, Brigham & Women’s Hospital Boston (BWH), University of California San Francisco (UC San Francisco), University of California (UC), Yale School of Medicine New Haven, Connecticut (YSM), University of Texas at Dallas Richardson (UT Dallas), Beth Israel Deaconess Medical Center Boston (BIDMC), Cancer Research Institute Boston, USA, Harvard Medical School Boston (HMS)-Harvard Medical School Boston (HMS), University of Iowa Iowa City, Genome Institute of Singapore (GIS), Memorial Sloane Kettering Cancer Center New York, Weill Medical College of Cornell University New York, This work was supported by the Howard Hughes Medical Institute and the National Cancer Institute (NIH) R01CA103846 (to L.I.Z.). L.I.Z. is a founder and stockholder of Fate, Inc., Scholar Rock, and a scientific advisor for Stemgent. J.L.T. is an Agency for Science, Technology & Research, Singapore National Science Scholarship recipient. C.B.G. is a PhRMA Foundation predoctoral fellow. R.A.Y. is a founder and stockholder of Syros Pharmaceuticals. This work was partially supported by NIH grants 2P01CA120964 (to J.M.A.), 5P30CA006516 (to J.M.A.), R01CA140485 (to T.H.K.), R21AI107067 (to T.H.K.), R01-ES023168 (to H.Y.C), and R01-HG004361 (to H.Y.C), We thank Min Yuan for her help with the metabolomics studies and Dr. Telmo Henriques for his advice on RNA assays.

المصدر: ISSN: 1097-2765.

مصطلحات موضوعية: MESH: Animals, MESH: Cell Line, Tumor, MESH: Pyrimidines / metabolism, MESH: RNA-Binding Proteins / genetics, MESH: RNA-Binding Proteins / metabolism, MESH: Transcription, Genetic, MESH: Tumor Suppressor Proteins / genetics, MESH: Zebrafish / genetics, MESH: Zebrafish Proteins / genetics, MESH: Zebrafish Proteins / metabolism, MESH: Gene Expression Regulation, Neoplastic, MESH: Humans, MESH: Melanoma / genetics, MESH: Melanoma / metabolism, MESH: Melanoma / pathology, MESH: Melanoma, Experimental, MESH: Oncogene Proteins / genetics, MESH: Positive Transcriptional Elongation Factor B / genetics, [SDV]Life Sciences [q-bio], [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27058786; pasteur-02871949; https://pasteur.hal.science/pasteur-02871949Test; PUBMED: 27058786; PUBMEDCENTRAL: PMC4836061

الإتاحة: https://doi.org/10.1016/j.molcel.2016.03.013Test
https://pasteur.hal.science/pasteur-02871949Test