نتائج البحث - "TSA, Trichostatin A"

1

TriTOX: A novel Trichomonas vaginalis assay platform for high-throughput screening of compound libraries

المؤلفون: Andrew M. Piggott, Samantha J. Emery-Corbin, Daniel Vuong, Aaron R. Jex, Ernest Lacey, Alexander Y.F. Lam

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss, Pp 68-80 (2021)
International Journal for Parasitology: Drugs and Drug Resistance

مصطلحات موضوعية: Special issue articles on 'Anaerobic Protozoan Pathogens: Drugs, Resistance and New Developments', 0301 basic medicine, Sexually transmitted disease, Microbial metabolites, HTS, High-throughput screen, Trichomonas, Tritrichomonas foetus, Infectious and parasitic diseases, RC109-216, medicine.disease_cause, 0302 clinical medicine, MTS, Medium-throughput screen, Drug-discovery, Pharmacology (medical), MIC, Minimum inhibitory concentration, MetAP2, Methionine aminopeptidase 2, Tritrichomonas, Natural products, Trichomoniasis, biology, Mtz, Metronidazole, Infectious Diseases, HIV, Human immunodeficiency virus, BLAST, Basic local alignment search tool, STD, Sexually-transmitted disease, I-TASSER, Iterative threading assembly refinement algorithm, medicine.drug, NI, Nitroimidazole, 030231 tropical medicine, PBS, Phosphate buffered saline, Microbiology, 03 medical and health sciences, Entamoeba histolytica, Metronidazole, parasitic diseases, Trichomonas vaginalis, medicine, Animals, Fumagillin, MOA, Mode of action, ADT, AutoDockTools, Pharmacology, DMSO, Dimethyl sulfoxide, biology.organism_classification, medicine.disease, High-Throughput Screening Assays, 030104 developmental biology, PDB, Protein data bank, Parasitology, Giardia lamblia, TSA, Trichostatin A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1638caa9d9810a926a7ef989e12ee1Test
https://doi.org/10.1016/j.ijpddr.2021.01.001Test

2

Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival

المؤلفون: Tram Anh Tran, Qing-Jun Zhang, Lei Wang, Christopher Gonzales, Luc Girard, Herman May, Thomas Gillette, Zhi-Ping Liu, Elisabeth D. Martinez

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Cardiomyopathy, Dilated, Jumonji Domain-Containing Histone Demethylases, Jumonji enzymes, IgG, immunoglobulin G, HDAC, histone deacetylase, Biochemistry, CnA, calcineurin A, Histones, Small Molecule Libraries, MEF2, myocyte enhancer factor 2, Mice, cDNA, complementary DNA, transcriptional reprogramming, GSEA, gene set enrichment analysis, Tg, transgenic, GO, Gene Ontology, TSA, trichostatin A, Animals, Humans, GEO, Gene Expression Omnibus, Enzyme Inhibitors, calcineurin, Molecular Biology, KO, knock-out, H3K9me3, trimethylation of histone 3 lysine 9, Histone Demethylases, TAC, transaortic constriction, Lysine, UTSW, UT Southwestern, HRP, horseradish peroxidase, mTORC1, mammalian target of rapamycin complex 1, Cell Biology, NFAT, nuclear factor of activated T-cell, H3K4me3, trimethylation of histone 3 lysine 4, JIB-04, LVAD, left ventricular assist device, cardiomyopathy, small-molecule inhibitor, EMT, epithelial-to-mesenchymal transition, MHC, myosin heavy chain, Research Article, KDM, histone lysine demethylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112f854788555475bb177a80293d9bd2Test
https://pubmed.ncbi.nlm.nih.gov/34933013Test

3

An acetylation-enhanced interaction between transcription factor Sox2 and the steroid receptor coactivators facilitates Sox2 transcriptional activity and function

المؤلفون: Jiemin Wong, Yuanyong Huang, Qingqing Guan, Jiwen Li, Li Kang, Xiaoya Duan, Lan Fang, Zhen Wang, Yimei Sun, Qiao Zhang

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Sox2, SRY-box 2, Transcription, Genetic, NCOAs, nuclear receptor coactivators, Biochemistry, Nuclear Receptor Coactivator 3, Mice, Nuclear Receptor Coactivator 2, Nuclear Receptor Coactivator 1, Transcription (biology), Transcriptional regulation, TSA, trichostatin A, SRC-1, AD2, activation domain 2, co-IP, co-immunoprecipitation, SRC-2, SRC-3, Acetylation, Cell biology, ChIP, chromatin immunoprecipitation, WB, Western blot, KLF4, embryonic structures, biological phenomena, cell phenomena, and immunity, transcription, Adult stem cell, Research Article, p300, Biology, steroid receptor coactivators, NAM, nicotinamide, SOX2, stomatognathic system, Coactivator, Animals, Humans, Molecular Biology, Transcription factor, NaCro, sodium crotonate, SOXB1 Transcription Factors, fungi, ES, embryonic stem, Cell Biology, pluripotency, SRCs, steroid receptor coactivators, HEK293 Cells, NRs, nuclear hormone receptors, Sox2 acetylation, sense organs, AD1, activation domain 1, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc871e08c423a1d049bce37de141753Test
http://europepmc.org/articles/PMC8668987Test

4

Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal CancerSummary

المؤلفون: David Horst, Markus Kaller, Thomas Kirchner, Matjaz Rokavec, Xiaolong Shi, Heiko Hermeking

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 391-418 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Male, Colorectal cancer, Kaplan-Meier Estimate, Receptor tyrosine kinase, Metastasis, Epigenesis, Genetic, 0302 clinical medicine, GSEA, gene set enrichment analysis, miRNA, microRNA, TSA, trichostatin A, STAT3, Dox, doxycycline, qPCR, quantitative real-time polymerase chain reaction, Colectomy, Original Research, Feedback, Physiological, Proctectomy, Gastroenterology, EMT, Prognosis, mRNA, messenger RNA, 5-aza, 5-aza-2’-deoxycytidine, Gene Expression Regulation, Neoplastic, CMS, consensus molecular subtype, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, DNA methylation, CRC, colorectal cancer, 030211 gastroenterology & hepatology, TAM, tumor-associated macrophage, Female, Fluorouracil, RTK, receptor tyrosine kinase, EMT, epithelial-mesenchymal transition, Colorectal Neoplasms, Chemoresistance, STAT3 Transcription Factor, Epithelial-Mesenchymal Transition, Colon, Biology, 03 medical and health sciences, cDNA, complementary DNA, Cell Line, Tumor, microRNA, medicine, COAD, colon adenocarcinoma, Humans, 5-FU, lcsh:RC799-869, Transcription factor, CRIS, colorectal cancer intrinsic subtype, PDX, patient-derived xenograft, Hepatology, VIM, vimentin, Rectum, DNA Methylation, medicine.disease, IL, interleukin, MicroRNAs, 030104 developmental biology, Tumor progression, siRNA, small interfering RNA, Drug Resistance, Neoplasm, Cancer research, biology.protein, Tumor Progression, TCGA, The Cancer Genome Atlas, 5-FU, 5-fluorouracil, CpG Islands, lcsh:Diseases of the digestive system. Gastroenterology, EMT-TF, epithelial-mesenchymal transition–inducing transcription factor, Tumor Suppressor Protein p53, CSF1R, colony-stimulating factor 1 receptor, MSP, methylation-specific polymerase chain reaction