Thermal dysregulation in patients with multiple sclerosis during SARS-CoV-2 infection. The potential therapeutic role of exercise
العنوان: | Thermal dysregulation in patients with multiple sclerosis during SARS-CoV-2 infection. The potential therapeutic role of exercise |
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المؤلفون: | Omid Razi, Bakhtyar Tartibian, Ana Maria Teixeira, Nastaran Zamani, Karuppasamy Govindasamy, Katsuhiko Suzuki, Ismail Laher, Hassane Zouhal |
المساهمون: | Razi University of Kermanshah, Allameh Tabataba’i University (ATU), University of Coimbra [Portugal] (UC), Payame Noor University, SRM Institute of Science and Technology (SRM), Faculty of Science and Engineering [Waseda], Waseda University [Tokyo, Japan], University of British Columbia (UBC), Laboratoire Mouvement Sport Santé (M2S), Université de Rennes (UR)-École normale supérieure - Rennes (ENS Rennes)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
المصدر: | Multiple Sclerosis and Related Disorders Multiple Sclerosis and Related Disorders, 2022, 59, pp.103557. ⟨10.1016/j.msard.2022.103557⟩ |
بيانات النشر: | Elsevier B.V., 2022. |
سنة النشر: | 2022 |
مصطلحات موضوعية: | eNOS, Endothelial nitric oxide synthase, PAMPs, [SDV]Life Sciences [q-bio], VEGF, Vascular endothelial growth factor, PGs, Prostaglandins, Review Article, PGE2, Prostaglandin E2, PACAP, EDHF, Endothelial-derived hyperpolarizing factor, APN, Adiponectin, PGE(2), thermoregulation, MS, Multiple sclerosis, CNS, Central nervous system, TRPV-1, Prostaglandin E(2), ROS, PACAP, Pituitary adenylate cyclase-activating polypeptide, General Medicine, VEGF, ANS Autonomic nervous system, Neurology, Pathogen-associated molecular patterns, eNOS, Adiponectin, CNS, severe acute respiratory syndrome coronavirus 2, Transient receptor potential vanilloid type 1, PAMPs, Pathogen-associated molecular patterns, Vasoactive intestinal peptide, Multiple Sclerosis, NLR family pyrin domain containing 3, SNS, Sympathetic nervous system, SNS, COVID-19, Coronavirus disease-2019, NO, Nitric oxide, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, sweat gland, NO, NLRP3, EDHF, PGs, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Humans, Pituitary adenylate cyclase-activating polypeptide, VDP, Exercise, NLRP3, NLR family pyrin domain containing 3, SARS-CoV-2, TRPV-1, Transient receptor potential vanilloid type 1, COVID-19, Nitric oxide, MS, VIP, Vasoactive intestinal peptide, VIP, APN, Vascular-dilating prostanoids, Central nervous system, Sympathetic nervous system, Coronavirus disease-2019, Prostaglandins, Endothelial-derived hyperpolarizing factor, Endothelial nitric oxide synthase, Neurology (clinical), Vascular endothelial growth factor, Nervous System Diseases, Reactive oxygen species, VDP, Vascular-dilating prostanoids, ROS, Reactive oxygen species |
الوصف: | International audience; Thermoregulation is a homeostatic mechanism that is disrupted in some neurological diseases. Patients with multiple sclerosis (MS) are susceptible to increases in body temperature, especially with more severe neurological signs. This condition can become intolerable when these patients suffer febrile infections such as coronavirus disease-2019 (COVID-19). We review the mechanisms of hyperthermia in patients with MS, and they may encounter when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Finally, the thermoregulatory role and relevant adaptation to regular physical exercise are summarized. |
اللغة: | English |
تدمد: | 2211-0356 2211-0348 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fb6c7e7228379d598dac62b600acd3Test http://europepmc.org/articles/PMC8785368Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....28fb6c7e7228379d598dac62b600acd3 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 22110356 22110348 |
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