المؤلفون: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)

مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1aTest
https://doi.org/10.1016/j.apsb.2021.07.021Test

المؤلفون: Po Hu, Hongzheng Wang, Xiaoxuan Yu, Wenzhuo Sun, Hui Hui, Hui Li, Mengyuan Zhu, Zhanyu Wang, Jingyan Xu, Qinglong Guo, Yingjie Qing

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3178-3192 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NPC, Niemann-Pick type disease C, Cathepsin D, ATG, autophagy related, NH4Cl, ammonium chloride, Lysosomal damage, Calcium in biology, Hematological malignancies, 0302 clinical medicine, RAB7A, RAS-related protein RAB-7a, K48, lysine 48, LC3, microtubule-associated protein 1 light chain 3, TFEB, transcription factor EB, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, RT-qPCR, real time quantitative PCR, Chemistry, LCD, lysosome-dependent cell death, CaN, calcineurin, P62/SQSTM1, sequestosome 1, Cell biology, TRPML1, transient receptor potential mucolipin 1, medicine.anatomical_structure, Cholesterol, 030220 oncology & carcinogenesis, shRNA, short hairpin RNA, Original Article, CsA, cyclosporine A, DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, Programmed cell death, AO, acridine orange, CTSD, cathepsin D, LW-218, PBS, phosphate-buffered saline, CTSB, cathepsin B, LMP, lysosome membrane permeabilization, EGTA, ethylene glycol-bis(2-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, RM1-950, Lysosome-dependent cell death, 03 medical and health sciences, Dex, dexamethasone, ROS, reactive oxygen species, FBS, fetal bovine serum, Lysosome, NPC1, NPC intracellular cholesterol transporter 1, medicine, BAF A1, bafilomycin A1, 030304 developmental biology, Cathepsin, PBMCs, peripheral blood mononuclear cells, Lysosomal membrane permeabilization, K63, lysine 63, Cell growth, DCFH-DA, 2,7-dichlorodi-hydrofluorescein diacetate, Autophagy, BID, BH3-interacting domain death agonist, Lysophagy, OD, optical density, TFEB, CCK8, Cell Counting Kit, Therapeutics. Pharmacology, LAMPs, lysosomal-associated membrane proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2bc1bb062d92dcf545995a174a1320Test
http://www.sciencedirect.com/science/article/pii/S2211383521000411Test