المؤلفون: Stevanović, Irena

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

مرشدي الرسالة: Stracker, Travis

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: TLS polymerase, TT dimmers, UV damage, Skin, Epidermal hyperplasia, Oxidative damage, Mitochondria, Fragile sites, Genomic instability, TLS polimerasa, Dímeros de timina, Daño por radiación ultravioleta, Piel, Hiperplasia epidérmica, Daño oxidativo, Mitocondrias, Sitios frágiles, Inestabilidad genómica

الوقت: 616.5

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/293265Test

المؤلفون: Anubrata Das, Georgios V. Gkoutos, Animesh Acharjee

المصدر: Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)

مصطلحات موضوعية: cancer, cetuximab, mutagenesis, network, TLS polymerase, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2045-7634Test

الوصول الحر: https://doaj.org/article/037c7f18aa384eae918af38199a4225fTest

المؤلفون: Ben Yamin, Barbara, Ahmed‐seghir, Sana, Tomida, Junya, Despras, Emmanuelle, Pouvelle, Caroline, Yurchenko, Andrey, Goulas, Jordane, Corre, Raphael, Delacour, Quentin, Droin, Nathalie, Dessen, Philippe, Goidin, Didier, Lange, Sabine, S, Bhetawal, Sarita, Mitjavila‐garcia, Maria, Teresa, Baldacci, Giuseppe, Nikolaev, Sergey, Cadoret, Jean, Charles, Wood, Richard, D, Kannouche, Patricia, L

المساهمون: Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), The University of Texas M.D. Anderson Cancer Center Houston, Institut Gustave Roussy (IGR), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Plateforme de Génomique Gustave Roussy, Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse (AMMICa), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Plateforme de Bioinformatique Gustave Roussy, Agilent Technologies France, Hôpital Paul Brousse, Institut Jacques Monod (IJM (UMR_7592)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)

المصدر: ISSN: 0261-4189.

مصطلحات موضوعية: DNA replication, heterochromatin, replication timing, REV3L, TLS polymerase Subject Categories Chromatin, Transcription & Genomics, Recombination & Repair, [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: hal-03353667; https://hal.sorbonne-universite.fr/hal-03353667Test; https://hal.sorbonne-universite.fr/hal-03353667/documentTest; https://hal.sorbonne-universite.fr/hal-03353667/file/embj.2020104543.pdfTest

الإتاحة: https://doi.org/10.15252/embj.2020104543Test
https://hal.sorbonne-universite.fr/hal-03353667Test
https://hal.sorbonne-universite.fr/hal-03353667/documentTest
https://hal.sorbonne-universite.fr/hal-03353667/file/embj.2020104543.pdfTest

المؤلفون: Guo Jiang (4583215), Jie Wang (16762), Dongdong Zhao (1681897), Xuxu Chen (8409636), Shiming Pu (6991505), Chunzhi Zhang (3455954), Ju Li (354128), Yaqiu Li (4862851), Jie Yang (121778), Siwei Li (144874), Xiaoping Liao (592112), Hongwu Ma (439532), Yanhe Ma (28802), Zuping Zhou (354844), Changhao Bi (1764364), Xueli Zhang (383859)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Plant Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, work first elucidates, work also suggests, specifically incorporating cs, polδ incorporates ts, base editing techniques, current hypothesis model, main tls polymerase, base editing process, engineering tls polymerases, base conversion process, base editing repair, base editing mechanism, ap sites created, conversions resulted mainly, ap sites caused, base editing, mainly caused, base editor, tls polymerases, model eukaryote, ap sites, polymerases knocked

العلاقة: https://figshare.com/articles/journal_contribution/Molecular_Mechanism_of_the_Cytosine_CRISPR_Base_Editing_Process_and_the_Roles_of_Translesion_DNA_Polymerases/17105299Test

الإتاحة: https://doi.org/10.1021/acssynbio.1c00293.s001Test

المؤلفون: Jenna Thomforde (7520021), Iwen Fu (1375938), Freddys Rodriguez (9930009), Suresh S. Pujari (2130463), Suse Broyde (14549), Natalia Tretyakova (64493)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, form Schiff base conjugates, AXA, TXA, polymerase η activity, neighbor base identity, GXA, CXT, CXA, CXC, CXG, DpC lesion, base sequence contexts, DNA, TLS polymerase η. Primer extension ., DPC, Molecular dynamics simulations, nucleotide sequence context

العلاقة: https://figshare.com/articles/journal_contribution/Translesion_Synthesis_Past_5_Formylcytosine-Mediated_DNA_Peptide_Cross-Links_by_hPol_Is_Dependent_on_the_Local_DNA_Sequence/14725295Test

الإتاحة: https://doi.org/10.1021/acs.biochem.1c00130.s001Test

المؤلفون: Barbara Ben Yamin, Philippe Dessen, Caroline Pouvelle, Raphael Corre, Jean Charles Cadoret, Giuseppe Baldacci, Richard D. Wood, Sabine S. Lange, Sergey Nikolaev, Sarita Bhetawal, Jordane Goulas, Quentin Delacour, Emmanuelle Despras, Maria Teresa Mitjavila-Garcia, Andrey A. Yurchenko, Sana Ahmed-Seghir, Patricia Kannouche, Didier Goidin, Nathalie Droin, Junya Tomida

المساهمون: Intégrité du génome et cancers (IGC), Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), The University of Texas M.D. Anderson Cancer Center [Houston], Institut Gustave Roussy (IGR), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Plateforme de Génomique [Gustave Roussy], Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse (AMMICa), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Plateforme de Bioinformatique [Gustave Roussy], Agilent Technologies France, Hôpital Paul Brousse, Institut Jacques Monod (IJM (UMR_7592)), Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Gestionnaire, HAL Sorbonne Université 5

المصدر: EMBO Journal
EMBO Journal, EMBO Press, 2021, 49, pp.8120-8134. ⟨10.15252/embj.2020104543⟩
The EMBO Journal
EMBO Journal, 2021, 49, pp.8120-8134. ⟨10.15252/embj.2020104543⟩

مصطلحات موضوعية: Genome instability, REV3L, TLS polymerase, DNA Replication, Recombination & Repair, DNA-Directed DNA Polymerase, Epigenesis, Genetic, Mice, 0302 clinical medicine, DNA Breaks, Double-Stranded, Recombination & Repair, Cell Line, Transformed, 0303 health sciences, biology, TLS polymerase Subject Categories Chromatin, General Neuroscience, Gene Expression Regulation, Developmental, Articles, Cell biology, DNA-Binding Proteins, Histone, Signal Transduction, DNA Replication, DNA damage, Heterochromatin, Mice, Transgenic, [SDV.CAN]Life Sciences [q-bio]/Cancer, replication timing, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, Transcription & Genomics, [SDV.CAN] Life Sciences [q-bio]/Cancer, Chromosomal Instability, Animals, Humans, Epigenetics, Molecular Biology, Embryonic Stem Cells, 030304 developmental biology, Cell Proliferation, Replication timing, General Immunology and Microbiology, DNA replication, heterochromatin, DNA, Fibroblasts, Embryo, Mammalian, Mice, Inbred C57BL, Chromobox Protein Homolog 5, Chromatin, Transcription & Genomics, biology.protein, NIH 3T3 Cells, Heterochromatin protein 1, 030217 neurology & neurosurgery, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecceeb3ccfb8f90285de395b8fd780e8Test
https://hal.sorbonne-universite.fr/hal-03353667Test

المؤلفون: Ryan P. Barnes, Kristin A. Eckert

المصدر: Oncotarget

مصطلحات موضوعية: Chemotherapy, Replication stress, biology, TLS polymerase, DNA polymerase, Chemistry, replication stress, medicine.medical_treatment, Editorial, Oncology, Cancer research, medicine, biology.protein, polymerase eta, ATR inhibitor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b38d570d659b14ac59e95c5150bd98Test
https://pubmed.ncbi.nlm.nih.gov/30774755Test

المؤلفون: Thomas E. Spratt, Vijay P. Jasti, Savithri Weerasooriya, Arindam Bose, Ashis K. Basu

المصدر: DNA Repair. 35:63-70

مصطلحات موضوعية: Nitrosamines, TLS polymerase, HEK293T, Tobacco-specific nitrosamine, DNA damage, NNK, O2-Methylthymidine, DNA-Directed DNA Polymerase, Biology, medicine.disease_cause, Biochemistry, Article, DNA Adducts, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tobacco, medicine, Humans, RNA, Small Interfering, Mutation frequency, Molecular Biology, siRNA knockdown, Carcinogen, 030304 developmental biology, 0303 health sciences, Mutagenesis, Cell Biology, O2-POB-thymidine, Molecular biology, HEK293 Cells, chemistry, Nitrosamine, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Mutation, Carcinogens, REV1, Thymidine, Genotoxicity, DNA Damage, Mutagens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa05c0fad4b34e373427e1e9c2fd4adcTest
https://doi.org/10.1016/j.dnarep.2015.09.023Test

المؤلفون: Ahmed-Seghir, Sana

مرشدي الرسالة: Paris 11, Kannouche, Patricia Laila

مصطلحات موضوعية: Réplication de l’ADN, Hétérochromatine, Timing de réplication, Polymérases TLS, Régions d’ADN non répliqué, Régions répliquées tardivement, DNA replication, Heterochromatin, Replication timing, TLS polymerase, Under-replicated region, Late replicating region

الإتاحة: http://www.theses.fr/2015PA11T052/documentTest

المؤلفون: Ahmed-Seghir, Sana

المساهمون: STAR, ABES, Stabilité Génétique et Oncogenèse (UMR 8200), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Université Paris Sud - Paris XI, Patricia Laila Kannouche

المصدر: Biologie cellulaire. Université Paris Sud-Paris XI, 2015. Français. ⟨NNT : 2015PA11T052⟩

مصطلحات موضوعية: TLS polymerase, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Régions répliquées tardivement, DNA replication, Réplication de l’ADN, Polymérases TLS, Under-replicated region, Hétérochromatine, Timing de réplication, Régions d’ADN non répliqué, Heterochromatin, Replication timing, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Late replicating region

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18d318269c4c831bbb47d1f11c59e9afTest
https://theses.hal.science/tel-01880505Test