المؤلفون: Ying Han, Xintong Zhang, Wei Huang, Zhonggao Gao, Mingji Jin

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: SLC, solute carrier, Bioavailability, AMI, amiodarone, MPA, mycophenolic acid, TLCA, taurolithocholate, ASP, amisulpride, RA, rheumatoid arthritis, Review, NRs, nitroreductases, MDR1, multidrug resistance gene 1, NaGC, sodium glycholate, MATEs, multidrug and toxin extrusion proteins, NMEs, new molecular entities, 0302 clinical medicine, HFD, high fat diet, P-gp, P-glycoprotein, ACS, amphipathic chitosan derivative, Medicine, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, 0303 health sciences, Gastrointestinal tract, IBD, inflammatory bowel disease, pKa, dissociation constant, RBC, red blood cell, FA, folate, OATs, organic anion transporters, 030220 oncology & carcinogenesis, MKC, monoketocholic acid, the GI tract, the gastrointestinal tract, AQP4, aquaporin 4, OCTNs, organic zwitterion/cation, T2D, type 2 diabetes, Gut microbiota, RM1-950, WHO, World Health Organization, 03 medical and health sciences, EcN, Escherichia coli Nissle 1917, Drug Transport Process, BDEPT, the bacteria-directed enzyme prodrug therapy, BCS, biopharmaceutics classification system, NEC, necrotizing enterocolitis, DRPs, digoxin reduction products, NaDC, sodium deoxycholate, Probiotics, CPP, cell-penetrating peptide, OCTs, organic cation transporters, TDCA, taurodeoxycholate, cgr operon, cardiac glycoside reductase operon, RA - Rheumatoid arthritis, DCA, deoxycholic acid, AA, ascorbic acid, BBR, berberine, Personalized medicine, BDDCS, the biopharmaceutics drug disposition classification system, SSZ, sulfasalazine, UDC, ursodeoxycholic acid, PPIs, proton pump inhibitors, BCRP, breast cancer resistance protein, CS, chitosan, Gut flora, Bioinformatics, PD, Parkinson's disease, SLN, solid lipid nanoparticle, SGLT-1, sodium-coupled glucose transporter 1, Oral administration, MRP2, multidrug resistance-associated protein 2, FAO, Food and Agriculture Organization of the United Nations, SVCT-1/2, the sodium-dependent vitamin C transporter-1/2, an OTC drug, an over-the-counter drug, CA, cholic acid, biology, ABC, ATP-binding cassette, T1DM, type 1 diabetes mellitus, NSAIDs, non-steroidal anti-inflammatory drugs, AR, azoreductase, GCDC, glycochenodeoxycholate, Drug delivery, GL, glycyrrhizic acid, PT, pectin, LPS, lipopolysaccharide, TME, the tumor microenvironment, T1D, type 1 diabetes, TCDC, taurochenodeoxycholate, Oral drugs, MDR1a, multidrug resistance protein-1a, SCFAs, short-chain fatty acids, CDCA, chenodeoxycholic acid, 030304 developmental biology, business.industry, dhBBR, dihydroberberine, biology.organism_classification, HTC, hematocrit, PWSDs, poorly water-soluble drugs, Colon-specific drug delivery system, stomatognathic diseases, SP, sulfapyridine, 5-ASA, 5-aminosalicylic acid, BSH, bile salt hydrolase, TCA, taurocholate, Therapeutics. Pharmacology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d001e27a816f9de7d75ff16dd2143ecTest
http://www.sciencedirect.com/science/article/pii/S2211383520307279Test

المؤلفون: Bruno Hagenbuch, Shipra Malhotra, Aron W. Fenton, Liskin Swint-Kruse, Melissa Ruggiero, John Karanicolas

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Taurocholic Acid, drug transport, Estrone, Kinetics, Protein Data Bank (RCSB PDB), PBS, phosphate-buffered saline, HEK293, human embryonic kidney 293 cells, Organic Anion Transporters, Sodium-Dependent, liver, Biochemistry, 03 medical and health sciences, NaCl, sodium chloride, single nucleotide polymorphism, PDB, Protein Data Bank, bile acid transport, hepatocyte, WT, wildtype, Humans, ASBTs, apical sodium-dependent bile acid transporters, Rosuvastatin Calcium, Molecular Biology, Integral membrane protein, chemistry.chemical_classification, Polymorphism, Genetic, 030102 biochemistry & molecular biology, SLC10A, solute carrier family 10A, Symporters, Chemistry, Protein Stability, HEK 293 cells, Wild type, Biological Transport, Cell Biology, computer.file_format, Protein Data Bank, Transmembrane protein, Amino acid, TBS, Tris-buffered saline, 030104 developmental biology, HEK293 Cells, Amino Acid Substitution, Biophysics, TCA, taurocholate, NTCP, Na+/TCA cotransporting polypeptide, computer, Research Article, TM, transmembrane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1342959ef3eb7d12e979ca49a3687606Test
http://europepmc.org/articles/PMC7948949Test

المؤلفون: Eric K. Kwong, Yunzhou Li, Phillip B. Hylemon, Huiping Zhou

المصدر: Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 151-157 (2015)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NTCP, sodium taurocholate cotransporting polypeptide, BSEP/ABCB11, bile salt export protein, Spns2, spinster homologue 2, Review, AKT/PKB, protein kinase B, SHP, small heterodimer partner, SRC, proto-oncogene tyrosine-protein kinase, 0302 clinical medicine, Sphingosine-1 phosphate receptor, G-6-Pase, glucose-6-phophatase, LDL, low-density lipoprotein, HNF4α, hepatocyte nuclear factor-4α, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, LRH-1, liver-related homolog-1, S1PR2, CA, cholic acid, 0303 health sciences, CYP7B1, oxysterol 7α-hydroxylase, Bile acid, ABC, ATP-binding cassette, Sphingosine Kinase 2, SphK, sphingosine kinase, FGF15/19, fibroblast growth factor 15/19, IBAT, ileal sodium-dependent bile acid transporter, CBA, conjugated bile acids, G protein-coupled bile acid receptor, 3. Good health, MMP, matrix metalloproteinase, TNFα, tumor necrosis factor α, SPHK2, Biochemistry, CYP8B1, 12α-hydroxylase, 030220 oncology & carcinogenesis, PTX, pertussis toxin, SPL, S1P lyase, Heptic lipid metabolism, Signal transduction, NAFLD, non-alcoholic fatty liver disease, FGFR, fibroblast growth factor receptor, medicine.drug_class, TGR5, G-protein-coupled bile acid receptor, Biology, S1PR2, sphingosine-1-phosphate receptor 2, M1–5, muscarinic receptor 1–5, NK, natural killer cells, SPPs, S1P phosphatases, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, CYP27A1, sterol 27-hydroxylase, medicine, Protein kinase B, S1P, sphingosine-1-phosphate, 030304 developmental biology, JNK1/2, c-Jun N-terminal kinase, ERK, extracellular regulated protein kinases, lcsh:RM1-950, VLDL, very-low-density lipoprotein, Lipid metabolism, PEPCK, PEP carboxykinse, CYP7A1, cholesterol 7α-hydroxylase, HDL, high density lipoprotein, EGFR, epidermal growth factor receptor, GPCR, G-protein coupled receptor, lcsh:Therapeutics. Pharmacology, DCA, deoxycholic acid, TCA, taurocholate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2081940d075535ab683fd5ac3182d0Test