-
1دورية أكاديمية
المؤلفون: I. I. Myrko, T. I. Chaban, V. V. Ohurtsov, I. V. Drapak, V. S. Matiichuk
المصدر: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 14, Iss 3, Pp 320-327 (2021)
مصطلحات موضوعية: organic synthesis, nmr spectroscopy, triazolo[3, 4-b][1, 4]thiadiazines, anticancer activity, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
العلاقة: http://pharmed.zsmu.edu.ua/article/view/240361/243381Test; https://doaj.org/toc/2306-8094Test; https://doaj.org/toc/2409-2932Test
-
2دورية أكاديمية
المؤلفون: I. І. Myrko, Yu. І. Horak, T. I. Chaban, І. V. Drapak, V. S. Matiychuk
المصدر: Фармацевтичний журнал, Vol 5, Pp 37-49 (2021)
مصطلحات موضوعية: organic synthesis, 3-r-6-(5-arylfuran-2-yl-[1, 4]triazolo[3, 4-b][1, 4]thiadiazole, antitumor activity, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
العلاقة: https://pharmj.org.ua/index.php/journal/article/view/1250/1173Test; https://doaj.org/toc/0367-3057Test; https://doaj.org/toc/2617-9628Test
-
3دورية أكاديمية
المؤلفون: Z. І. Сhulovska, І. V. Drapak, T. I. Chaban, V. S. Matiychuk, I. G. Chaban, V. V. Ogurtsov
المصدر: Фармацевтичний журнал, Vol 1, Pp 17-25 (2021)
مصطلحات موضوعية: organic synthesis, 4-thioxothiazolidin-2-one, 4-iminothiazolidin-2-one, antioxidant activity, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
العلاقة: https://pharmj.org.ua/index.php/journal/article/view/1177/1031Test; https://doaj.org/toc/0367-3057Test; https://doaj.org/toc/2617-9628Test
-
4دورية أكاديمية
المؤلفون: T. I. Chaban, V. S. Matiychuk, V. V. Ogurtsov, I. G. Chaban, I. A. Nektegayev
المصدر: The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 132-139 (2020)
مصطلحات موضوعية: anti-inflammatory activity, molecular docking, organic synthesis, thiazolo[4, 5-b]pyridines, Biochemistry, QD415-436, Medicine, Biology (General), QH301-705.5
وصف الملف: electronic resource
العلاقة: http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Chaban_2_20.pdfTest; https://doaj.org/toc/2409-4943Test; https://doaj.org/toc/2413-5003Test
-
5دورية أكاديمية
المصدر: Журнал органічної та фармацевтичної хімії, Vol 17, Iss 3, Pp 15-20 (2019)
مصطلحات موضوعية: organic synthesis, thiazolopyridines, antioxidant activity, Chemistry, QD1-999
وصف الملف: electronic resource
العلاقة: http://ophcj.nuph.edu.ua/article/view/ophcj.19.174239/177690Test; https://doaj.org/toc/2308-8303Test; https://doaj.org/toc/2518-1548Test
-
6دورية أكاديمية
المؤلفون: T. I. Chaban, V. V. Ohurtsov, V. S. Matiichuk, O. V. Honcharenko, I. H. Chaban
المصدر: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 12, Iss 2, Pp 129-134 (2019)
مصطلحات موضوعية: thiazolo[4, 5-b]pyridines, cyanethylation, hydrolysis, acylation, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
العلاقة: http://pharmed.zsmu.edu.ua/article/view/170974/172660Test; https://doaj.org/toc/2306-8094Test; https://doaj.org/toc/2409-2932Test
-
7دورية أكاديمية
المؤلفون: I. I. Myrko, T. I. Chaban, V. V. Ogurtsov, V. S. Matiychuk
المصدر: Фармацевтичний часопис, Iss 1, Pp 5-13 (2021)
مصطلحات موضوعية: органічний синтез, ямр-спектроскопія, 1-арил-4-{3-арил(гетарил)-7h-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазин-6-іл)}-5-метил-1h-піразол-3-карбоксилати, антимікробна активність, Pharmacy and materia medica, RS1-441
العلاقة: https://ojs.tdmu.edu.ua/index.php/pharm-chas/article/view/11986Test; https://doaj.org/toc/2312-0967Test; https://doaj.org/toc/2414-9926Test; https://doaj.org/article/1df91b446e334306b7baa9caf4699c38Test
الإتاحة: https://doi.org/10.11603/2312-0967.2021.1.11986Test
https://doaj.org/article/1df91b446e334306b7baa9caf4699c38Test -
8دورية أكاديميةSynthesis of some new thiazolo[4,5-b]pyridin-2-ones and research of their anti-inflammatory activity
المؤلفون: T. I. Chaban
المصدر: Фармацевтичний журнал, Vol 4, Iss 4, Pp 52-60 (2019)
مصطلحات موضوعية: thiazolo[4, 5-b]pyridine-2-ones, synthesis, anti-inflammatory activity, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441
العلاقة: https://pharmj.org.ua/index.php/journal/article/view/618/581InTest modern theoretical and clinical medicine inflammation problem remains one of the main.Deregulation of inflammatory processes leads to specific pathologies.There is a significant amount of drugs used to treat inflammation. But all of them have varying degrees of ulcerogenic properties. To overcome these limitations search is ongoing throughout the World to find new effective and safe anti-inflammatory agent. Therefore, of course, the synthesis of thiazolidines annelated with the pyridine cycle and the study of their anti-inflammatory properties is an interesting and relevant area. The objective of the present work was to synthesize a series of novel thiazolo[4,5-b]pyridine-2-ones by the structural modification of the (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide for further pharmacological screening in vivo as anti-inflammatory activities. The objects of the study were thiazolo[4,5-b]pyridines, obtained by the structural modification of the (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide. Anti-inflammatory activity was evaluated using carrageenan induced rat paw edema method in rats In vivo studies were carried out for anti-inflammatory activity employing the carrageenan-induced rat paw edema method. Anti-inflammatory activity was defined by measuring the paw edema volume 4 h after the carrageenan injection.The NSAID drug Ibuprofen in effective therapeutic doses were tested inparallel as an activity references. Inhibition of the inflammatory response was expressed as a percentage of the paw volume reduction. Studies of anti-inflammatory activity showed that the synthesized compounds had pronounced diuretic properties, and some of them according to activity indicators were approaching or exceeding comparative preparations. The results of the anti-inflammatory activity of the synthesized compounds derivatives (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide show the potential for the search for anti-inflammatory agents among thiazolo[4,5-b]pyridine-2-ones.; https://doaj.org/toc/0367-3057Test; https://doaj.org/toc/2617-9628Test; https://doaj.org/article/439df6ec1a044367b63ff1b67462145fTest
الإتاحة: https://doi.org/10.32352/0367-3057.4.19.06Test
https://doaj.org/article/439df6ec1a044367b63ff1b67462145fTest -
9دورية أكاديمية
المؤلفون: T. I. Chaban
المصدر: Фармацевтичний часопис, Iss 1, Pp 19-24 (2019)
مصطلحات موضوعية: тіазоло[4,5-b]піридини, ціанетилювання, алкілювання, Pharmacy and materia medica, RS1-441
العلاقة: https://ojs.tdmu.edu.ua/index.php/pharm-chas/article/view/9930Test; https://doaj.org/toc/2312-0967Test; https://doaj.org/toc/2414-9926Test; https://doaj.org/article/b3f07908711a40c7b6fa12b1470b8d97Test
الإتاحة: https://doi.org/10.11603/2312-0967.2019.1.9930Test
https://doaj.org/article/b3f07908711a40c7b6fa12b1470b8d97Test -
10
المؤلفون: T. I. Chaban, Vasyl S. Matiychuk, Iryna Myrko
المصدر: Current Chemistry Letters, Vol 11, Iss 1, Pp 75-82 (2022)
مصطلحات موضوعية: Strain (chemistry), biology, Chemistry, Pseudomonas, General Chemistry, Pyrazole, Acinetobacter, Antimicrobial, biology.organism_classification, medicine.disease_cause, Microbiology, chemistry.chemical_compound, medicine, QD1-999, Staphylococcus, Biological evaluation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbd50572de005fbd4a795e1d1f698ccTest
https://doi.org/10.5267/j.ccl.2021.9.003Test