المؤلفون: Nguyen, Tra Ly, Nokin, Marie-Julie, Terés, Silvia, Tomé, Mercedes, Bodineau, Clément, Galmar, Oriane, Pasquet, Jean-Max, Rousseau, Benoit, Liempd, Sebastian van, Falcón-Pérez, Juan M., Richard, Elodie, Muzotte, Elodie, Rezvani, Hamid-Reza, Priault, Muriel, Bouchecareilh, Marlon, Redonnet-Vernhet, Isabelle, Calvo, Julien, Uzan, Benjamin, Pflumio, Françoise, Fuentes, Patricia, Toribio, María L., Khatib, Abdel-Majid, Soubeyran, Pierre, Murdoch, Piedad del S., Durán, Raúl V.

المساهمون: Agencia Estatal de Investigación (España), European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), Consejo Superior de Investigaciones Científicas (España), Institut National de la Santé et de la Recherche Médicale (France), Ligue Nationale contre le Cancer (France), Université de Bordeaux, Fondation pour la Recherche Médicale, Conseil régional d'Aquitaine, Fondation ARC pour la Recherche sur le Cancer, Fonds de la Recherche Scientifique (Fédération Wallonie-Bruxelles)

مصطلحات موضوعية: Glutamine, Glutamine synthetase, Metabolicaddiction, mTORC1, Notch1, T-cell acutelymphoblastic leukemia

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-096244-B-I00/ES/DESEQUILIBRIO NUTRICIONAL E INDUCCION DE MUERTE CELULAR EN CANCER: ASPECTOS FUNDAMENTALES Y TRANSLACIONALES DE LA GLUTAMOPTOSIS/; info:eu-repo/grantAgreement/EC/MINECO//SAF2016-75442-R; Publisher's version; http://dx.doi.org/10.1002/1878-0261.12877Test; Sí; Molecular Oncology 15: 1412-1431 (2021); http://hdl.handle.net/10261/264345Test; http://dx.doi.org/10.13039/501100002661Test; http://dx.doi.org/10.13039/501100009468Test; http://dx.doi.org/10.13039/501100003339Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100004097Test; http://dx.doi.org/10.13039/501100006251Test; http://dx.doi.org/10.13039/501100002915Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/501100004099Test; http://dx.doi.org/10.13039/501100001677Test; http://dx.doi.org/10.13039/501100011033Test

الإتاحة: https://doi.org/10.1002/1878-0261.12877Test
https://doi.org/10.13039/501100002661Test
https://doi.org/10.13039/501100009468Test
https://doi.org/10.13039/501100003339Test
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100004097Test
https://doi.org/10.13039/501100006251Test
https://doi.org/10.13039/501100002915Test
https://doi.org/10.13039/501100003329Test
https://doi.org/10.13039/501100004099Test

المؤلفون: Clément Bodineau, Benjamin Uzan, Sebastian van Liempd, Jean-Max Pasquet, Juan M. Falcón-Pérez, Elodie Muzotte, H. Rezvani, Julien Calvo, Elodie Richard, María L. Toribio, Patricia Fuentes, Isabelle Redonnet-Vernhet, Silvia Terés, Marion Bouchecareilh, Mercedes Tomé, Pierre Soubeyran, Piedad del Socorro Murdoch, Benoit Rousseau, Tra Ly Nguyen, Françoise Pflumio, Marie-Julie Nokin, Oriane Galmar, Raúl V. Durán, Abdel-Majid Khatib, Muriel Priault

المساهمون: Centre National de la Recherche Scientifique (CNRS), Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular, Ministerio de Ciencia, Innovación y Universidades (MICINN). España, European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER), Agencia Estatal de Investigación (España), European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), Consejo Superior de Investigaciones Científicas (España), Institut National de la Santé et de la Recherche Médicale (France), Ligue Nationale contre le Cancer (France), Université de Bordeaux, Fondation pour la Recherche Médicale, Conseil régional d'Aquitaine, Fondation ARC pour la Recherche sur le Cancer, Fonds de la Recherche Scientifique (Fédération Wallonie-Bruxelles), Actions for OnCogenesis understanding and Target Identification in ONcology (ACTION), Institut Bergonié [Bordeaux], UNICANCER-UNICANCER-Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Angiogenèse et Micro-environnement des Cancers (LAMC), Université Sciences et Technologies - Bordeaux 1-Institut National de la Santé et de la Recherche Médicale (INSERM), Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de biochimie et génétique cellulaires (IBGC), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Bordeaux Research In Translational Oncology [Bordeaux] (BaRITOn), Université de Bordeaux (UB)-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), [Nguyen,TL, Nokin,MJ, Terés,S, Bodineau,C, Galmnar,O, Durán,RV] Institut Europeen de Chimie et Biologie, INSERM U1218, Université de Bordeaux, Pessac, France. [Tomé,M, Murdoch,PDS, Durán,RV] Centro Andaluz de Biología Molecular y Medicina Regenerativa - CABIMER, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Universidad Pablo de Olavide, Seville, Spain. [Tomé,M, Khatib,AM] Angiogenesis and Cancer Microenvironment Laboratory INSERM U1029, Universite de Bordeaux, Pessac, France. [Pasquet,JM, Muzotte,E, Rezvani,HR] INSERM, BMGIC, U1035, University of Bordeaux, France. [Rousseau,B] Service Commun des Animaleries, University of Bordeaux, France. [van Liempd,S, Falcon-Perez,JM] Exosomes Laboratory and Platform of Metabolomics, CIC bioGUNE, CIBERehd, Derio, Spain. [Falcon-Perez,JM] IKERBASQUE, Basque Foundation for Science, Bilbao, Spain. [Richard,E] Institut Bergonie, INSERM U1218, University of Bordeaux, France. [Priault,M] Institut de Biochimie et Gen etique Cellulaires, CNRS UMR 5095, Université de Bordeaux, France. [Bouchecareilh,M] Bordeaux Research in Translational Oncology, INSERM U1053, Universite de Bordeaux, France. [Redonnet-Vernhet,I] Maladies Heréditaires du Métabolisme, Laboratoire de Biochimie, Hôpital Pellegrin, CHU Bordeaux, France. [Calvo,J, Uzan,B, Pflumio, F] UMR967, Inserm, CEA, Universite Paris 7, UniversitéParis 11, Fontenay-aux-Roses, France. [Fuentes,P, Toribio,ML] Centro de Biología Molecular 'Severo Ochoa', Consejo Superior de Investigaciones Científicas, Universidad Autonoma de Madrid, Spain. [Murdoch,PDS] Departamento de Bioquímica Vegetal y Biología Molecular, Universidad de Sevilla, Spain, This work was supported by funds from the following institutions: Agencia Estatal de Investigación/European Regional Development Fund, European Union (PGC2018-096244-B-I00, SAF2016-75442-R), Ministry of Science, Innovation and Universities of Spain, Spanish National Research Council—CSIC, Institut National de la Santé et de la Recherche Médicale—INSERM, Ligue Contre le Cancer—Gironde, Université de Bordeaux, Fondation pour la Recherche Médicale, the Conseil Régional d'Aquitaine, SIRIC-BRIO, Fondation ARC and Institut Européen de Chimie et Biologie. MJN was supported by a bourse d’excellence de la Fédération Wallonie-Bruxelles (WBI) and a postdoctoral fellowship from Fondation ARC. We thank Vincent Pitard (Flow Cytometry Platform, Université de Bordeaux, France) for technical assistance in flow cytometry experiments. We thank Diana Cabrera (Metabolomics Platform, CIC bioGUNE, Spain) for technical assistance in metabolomics analysis.

المصدر: Molecular Oncology
Molecular Oncology, Elsevier, 2021, 15 (5), pp.1412-1431. ⟨10.1002/1878-0261.12877⟩
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Oncology, Elsevier, 2021, 15, pp.1412-1431. ⟨10.1002/1878-0261.12877⟩
Digital.CSIC. Repositorio Institucional del CSIC
Molecular Oncology, Vol 15, Iss 5, Pp 1412-1431 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor [Medical Subject Headings], Cancer Research, Glutamina, Regulación hacia abajo, [SDV]Life Sciences [q-bio], Glutamine, mTORC1, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Diana mecanicista del complejo 1 de la rapamicina, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Mice, 0302 clinical medicine, Mice, Inbred NOD, hemic and lymphatic diseases, Organisms::Eukaryota::Animals [Medical Subject Headings], Receptor, Notch1, Research Articles, RC254-282, ComputingMilieux_MISCELLANEOUS, Metabolismo, Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes [Medical Subject Headings], Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice, Inbred Strains::Mice, Inbred NOD [Medical Subject Headings], Chemistry, Gene Expression Regulation, Leukemic, Línea celular, Metabolicaddiction, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], Neoplasms. Tumors. Oncology. Including cancer and carcinogens, General Medicine, Precursor Cell Lymphoblastic Leukemia-Lymphoma, 3. Good health, Leukemia, Oncology, 030220 oncology & carcinogenesis, embryonic structures, cardiovascular system, Molecular Medicine, biological phenomena, cell phenomena, and immunity, Glutamato-amoníaco ligasa, T-cell acute lymphoblastic leukemia, Research Article, Signal Transduction, Receptor Notch1, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Notch::Receptor, Notch1 [Medical Subject Headings], Down-Regulation, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic::Gene Expression Regulation, Leukemic [Medical Subject Headings], Check Tags::Male [Medical Subject Headings], Mice, Transgenic, [SDV.CAN]Life Sciences [q-bio]/Cancer, Mechanistic Target of Rapamycin Complex 1, Gene Expression Regulation, Enzymologic, Glutamine synthetase, 03 medical and health sciences, Downregulation and upregulation, Glutamate-Ammonia Ligase, Cell Line, Tumor, T‐cell acute lymphoblastic leukemia, Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Lymphoid::Precursor Cell Lymphoblastic Leukemia-Lymphoma [Medical Subject Headings], Genetics, medicine, Animals, Humans, Metabolic addiction, T-cell acutelymphoblastic leukemia, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Notch1, Glutaminolysis, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation [Medical Subject Headings], Cell growth, Leucemia-linfoma linfoblástico de células T precursoras, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Basic::Glutamine [Medical Subject Headings], medicine.disease, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Ligases::Carbon-Nitrogen Ligases::Amide Synthases::Glutamate-Ammonia Ligase [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Enzymologic [Medical Subject Headings], 030104 developmental biology, Apoptosis, Downregulation, metabolic addiction, Cancer research, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Transgenic [Medical Subject Headings], sense organs, Cell line

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274dd93100a7d24ada66a7c0aca2aad0Test
https://hal-cnrs.archives-ouvertes.fr/hal-03401225Test

مصطلحات الفهرس: Glutamine, Glutamine synthetase, Metabolicaddiction, mTORC1, Notch1, T-cell acutelymphoblastic leukemia, artículo

URL: http://hdl.handle.net/10261/264345Test
Publisher's version
http://dx.doi.org/10.1002/1878-0261.12877Test
Sí
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-096244-B-I00/ES/DESEQUILIBRIO NUTRICIONAL E INDUCCION DE MUERTE CELULAR EN CANCER: ASPECTOS FUNDAMENTALES Y TRANSLACIONALES DE LA GLUTAMOPTOSIS
info:eu-repo/grantAgreement/EC/MINECO//SAF2016-75442-R

مصطلحات الفهرس: Glutamine, Glutamine synthetase, Metabolicaddiction, mTORC1, Notch1, T-cell acutelymphoblastic leukemia, artículo

URL: http://hdl.handle.net/10261/259154Test
Publisher's version
http://dx.doi.org/10.1002/1878-0261.12877Test
Sí
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-096244-B-I00/ES/DESEQUILIBRIO NUTRICIONAL E INDUCCION DE MUERTE CELULAR EN CANCER: ASPECTOS FUNDAMENTALES Y TRANSLACIONALES DE LA GLUTAMOPTOSIS
info:eu-repo/grantAgreement/EC/MINECO//SAF2016-75442-R