المؤلفون: Bogacheva, Mariia, Kuivanen, Suvi, Potdar, Swapnil, Hassinen, Antti, Huuskonen, Sini, Pöhner, Ina, Luck, Tamara J., Turunen, Laura, Feodoroff, Michaela, Szirovicza, Leonóra, Savijoki, Kirsi, Saarela, Jani, Tammela, Päivi, Paavolainen, Lassi, Poso, Antti, Varjosalo, Markku, Kallioniemi, Olli, Pietiäinen, Vilja, Vapalahti, Olli

المساهمون: Department of Virology, Medicum, Institute for Molecular Medicine Finland, Helsinki Institute of Life Science HiLIFE, Viral Zoonosis Research Unit, Institute of Biotechnology, Molecular Systems Biology, Division of Pharmaceutical Biosciences, Drug Research Program, Faculty of Pharmacy, Division of Pharmaceutical Chemistry and Technology, Bioactivity Screening Group, Bioimage Profiling, Precision Systems Medicine, Helsinki One Health (HOH), HUSLAB, Veterinary Microbiology and Epidemiology, Veterinary Biosciences, Olli Pekka Vapalahti / Principal Investigator, HUS Diagnostic Center

مصطلحات موضوعية: 11832 Microbiology and virology, 3121 General medicine, internal medicine and other clinical medicine, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: The authors thank Minerva Institute (Helsinki, Finland) for providing utilities for the project; the FIMM High Throughput Biomedicine Unit for providing access to HT robotics, the FIMM High Content Imaging and Analysis Unit for HC imaging and analysis, and FIMM Genomics unit for genotyping services (HiLIFE, University of Helsinki and Biocenter Finland) . The authors acknowledge the CSC-IT Center for Science Ltd. for computational resources. The grants awarded by the Academy of Finland [grant numbers iCOIN-336496: OK, VP, OV; FIRI 2020-337036: FIMM-HCA, AH, VP] , the EU H2020 VEO project (OV) , Juho Vainio foundation, anonymous donors through Helsinki University Research funds (OV) and Minerva Foundation for the COVID19 research project grant (VP) are also greatly acknowledged. The authors thank Katja Rosti, University of Helsinki, Dr. Petri Saviranta, and Sirpa Jylha , VTT, Finland for the supply of 7A12 antibodies against SARS-CoV-2 S protein. The authors thank Prof. Kari Alitalo for providing a fluorescence reader at BSL-3 and Alyce Whipp for checking the English language grammar in the manuscript.; Bogacheva , M , Kuivanen , S , Potdar , S , Hassinen , A , Huuskonen , S , Pöhner , I , Luck , T J , Turunen , L , Feodoroff , M , Szirovicza , L , Savijoki , K , Saarela , J , Tammela , P , Paavolainen , L , Poso , A , Varjosalo , M , Kallioniemi , O , Pietiäinen , V & Vapalahti , O 2024 , ' Drug repurposing platform for deciphering the druggable SARS-CoV-2 interactome ' , Antiviral Research , vol. 223 , 105813 . https://doi.org/10.1016/j.antiviral.2024.105813Test; ORCID: /0000-0001-7306-7175/work/152924410; ORCID: /0000-0003-2270-6824/work/152925170; ORCID: /0000-0003-3125-2406/work/152926687; ORCID: /0000-0003-4697-8066/work/152926723; ORCID: /0000-0003-1528-044X/work/152927229; ORCID: /0000-0002-1340-9732/work/152927567; ORCID: /0000-0002-6094-9838/work/152928335; ORCID: /0000-0003-3857-1805/work/152931879; ORCID: /0000-0001-9491-2868/work/152932584; ORCID: /0000-0002-9859-1261/work/152932735; ORCID: /0000-0003-1508-2718/work/152933216; ORCID: /0000-0002-2778-6918/work/152933252; ORCID: /0000-0001-6608-1120/work/152933672; ORCID: /0000-0003-0274-4794/work/155648905; http://hdl.handle.net/10138/571055Test; 05032077-daad-4120-a874-3c60fa96febb; 001177707500001

الإتاحة: http://hdl.handle.net/10138/571055Test

المؤلفون: Khalfi, Pierre, Denis, Zoe, McKellar, Joe, Merolla, Giovanni, Chavey, Carine, Ursic-Bedoya, Jose, Soppa, Lena, Szirovicza, Leonora, Hetzel, Udo, Dufourt, Jeremy, Leyrat, Cedric, Goldmann, Nora, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F., Glebe, Dieter, Courgnaud, Valerie, Gregoire, Damien, Hepojoki, Jussi, Majzoub, Karim

المساهمون: Department of Virology, Viral Zoonosis Research Unit, Medicum, Helsinki One Health (HOH)

مصطلحات موضوعية: Hepatitis-b-virus, Arginine-rich motifs, Rna-binding-activity, Envelope protein, Surface-antigen, Localization, Transcription, Nucleus, Genome, Site, 3111 Biomedicine, 11832 Microbiology and virology

وصف الملف: application/pdf

العلاقة: The project was funded by the ATIP-AVENIR program (CNRS- INSERM), the MUSE (Montpellier Universite d'Excellence) grant, by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) to D.G. project number 197785619 (SFB 1021) and the European Research Council (ERC) starting grant 101039538 - DELV. P. K. was supported by the ATIP-AVENIR program (CNRS- INSERM), K.M., Z. D. and J. M. were supported by the European Research Council (ERC) starting grant 101039538 - DELV. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Khalfi , P , Denis , Z , McKellar , J , Merolla , G , Chavey , C , Ursic-Bedoya , J , Soppa , L , Szirovicza , L , Hetzel , U , Dufourt , J , Leyrat , C , Goldmann , N , Goto , K , Verrier , E , Baumert , T F , Glebe , D , Courgnaud , V , Gregoire , D , Hepojoki , J & Majzoub , K 2024 , ' Comparative analysis of human, rodent and snake deltavirus replication ' , PLoS Pathogens , vol. 20 , no. 3 , e1012060 . https://doi.org/10.1371/journal.ppat.1012060Test; ORCID: /0000-0001-5699-214X/work/156646171; ORCID: /0000-0003-1528-044X/work/156647332; http://hdl.handle.net/10138/573977Test; 7e125e03-1d42-425f-b34d-8f8407569b83; 001181564300001

الإتاحة: http://hdl.handle.net/10138/573977Test

المؤلفون: Bogacheva, Mariia S., Kuivanen, Suvi, Potdar, Swapnil, Hassinen, Antti, Huuskonen, Sini, Pöhner, Ina, Luck, Tamara J., Turunen, Laura, Feodoroff, Michaela, Szirovicza, Leonora, Savijoki, Kirsi, Saarela, Jani, Tammela, Päivi, Paavolainen, Lassi, Poso, Antti, Varjosalo, Markku, Kallioniemi, Olli, Pietiäinen, Vilja, Vapalahti, Olli

المصدر: Antiviral Research ; volume 223, page 105813 ; ISSN 0166-3542

مصطلحات موضوعية: Virology, Pharmacology

الإتاحة: https://doi.org/10.1016/j.antiviral.2024.105813Test
https://api.elsevier.com/content/article/PII:S0166354224000214?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0166354224000214?httpAccept=text/plainTest

المؤلفون: Lintala, Annika, Szirovicza, Leonora, Kipar, Anja, Hetzel, Udo, Hepojoki, Jussi

المساهمون: Department of Virology, University of Helsinki, Medicum, Viral Zoonosis Research Unit, Faculty of Veterinary Medicine, Helsinki One Health (HOH)

مصطلحات موضوعية: arenavirus, cell culture, coinfection, persistence, LYMPHOCYTIC CHORIOMENINGITIS VIRUS, INCLUSION-BODY DISEASE, ARENAVIRUSES, SNAKES, REPLICATION, INHIBITION, 11832 Microbiology and virology

وصف الملف: application/pdf

العلاقة: The study was supported by the Academy of Finland (J.H.; grants 308613, 314119, and 335762).; Lintala , A , Szirovicza , L , Kipar , A , Hetzel , U & Hepojoki , J 2022 , ' Persistent Reptarenavirus and Hartmanivirus Infection in Cultured Boid Cells ' , Microbiology Spectrum , vol. 10 , no. 4 , e0158522 . https://doi.org/10.1128/spectrum.01585-22Test; ORCID: /0000-0001-5699-214X/work/127502173; ORCID: /0000-0003-1528-044X/work/127508895; a9a06d42-a1ed-4cef-bffc-d977c59228b2; http://hdl.handle.net/10138/353714Test; 000823148800004

الإتاحة: http://hdl.handle.net/10138/353714Test

المؤلفون: Khalfi, Pierre, Denis, Zoé, Merolla, Giovanni, Chavey, Carine, Ursic-Bedoya, José, Soppa, Lena, Szirovicza, Leonora, Hetzel, Udo, Dufourt, Jeremy, Leyrat, Cedric, Goldmann, Nora, Goto, Kaku, Verrier, Eloi, Baumert, Thomas, F, Glebe, Dieter, Courgnaud, Valérie, Grégoire, Damien, Hepojoki, Jussi, Majzoub, Karim

المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Universität Zürich Zürich = University of Zurich (UZH), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Virology Helsinki, Haartman Institute Helsinki, Faculty of Medecine Helsinki, Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Faculty of Medecine Helsinki, Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, The project was funded by the ATIP-AVENIR program (CNRS- INSERM), the MUSE (Montpellier Université d’Excellence) grant, by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) to D.G. project number 197785619 (SFB 1021) and the European Research Council (ERC) starting grant 101039538 – DELV.

المصدر: https://hal.science/hal-04209863Test ; 2023.

مصطلحات موضوعية: HDV-like viruses, HDV, hydrodynamic injections, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

العلاقة: hal-04209863; https://hal.science/hal-04209863Test; https://hal.science/hal-04209863/documentTest; https://hal.science/hal-04209863/file/2023%20Khalfi,%20Denis%20et%20al.%20biorxiv.pdfTest; BIORXIV: 2023.05.17.541162

الإتاحة: https://hal.science/hal-04209863Test
https://hal.science/hal-04209863/documentTest
https://hal.science/hal-04209863/file/2023%20Khalfi,%20Denis%20et%20al.%20biorxiv.pdfTest

المؤلفون: Lintala, Annika, Szirovicza, Leonora, Kipar, Anja, Hetzel, Udo, Hepojoki, Jussi

المساهمون: Richard, Mathilde, Richard, M ( Mathilde )

المصدر: Lintala, Annika; Szirovicza, Leonora; Kipar, Anja; Hetzel, Udo; Hepojoki, Jussi (2022). Persistent Reptarenavirus and Hartmanivirus Infection in Cultured Boid Cells. Microbiology Spectrum, 10(4):e0158522.

مصطلحات موضوعية: Institute of Veterinary Pathology, 570 Life sciences, biology, Infectious Diseases, Cell Biology, Microbiology (medical), Genetics, General Immunology and Microbiology, Ecology, Physiology

وصف الملف: application/pdf

العلاقة: https://www.zora.uzh.ch/id/eprint/224541/8/ZORA224541.pdfTest; info:pmid/35862992; urn:issn:2165-0497

الإتاحة: https://doi.org/10.5167/uzh-22454110.1128/spectrum.01585-22Test
https://www.zora.uzh.ch/id/eprint/224541Test/
https://www.zora.uzh.ch/id/eprint/224541/8/ZORA224541.pdfTest

المؤلفون: Szirovicza, Leonora, Hetzel, Udo, Kipar, Anja, Hepojoki, Jussi

المصدر: Szirovicza, Leonora; Hetzel, Udo; Kipar, Anja; Hepojoki, Jussi (2022). Short ‘1.2× Genome’ Infectious Clone Initiates Kolmiovirid Replication in Boa constrictor Cells. Viruses, 14(1):107.

مصطلحات موضوعية: Institute of Veterinary Pathology, 570 Life sciences, biology, Virology, Infectious Diseases

وصف الملف: application/pdf

العلاقة: https://www.zora.uzh.ch/id/eprint/216721/1/viruses-14-00107-v2.pdfTest; info:pmid/35062311; urn:issn:1999-4915

الإتاحة: https://doi.org/10.5167/uzh-21672110.3390/v14010107Test
https://www.zora.uzh.ch/id/eprint/216721Test/
https://www.zora.uzh.ch/id/eprint/216721/1/viruses-14-00107-v2.pdfTest

المؤلفون: Rusanen, Juuso, Kareinen, Lauri, Szirovicza, Leonóra, Ugurlu, Hasan, Levanov, Lev, Jääskeläinen, Anu, Ahava, Maarit J, Kurkela, Satu, Saksela, Kalle, Hedman, Klaus, Vapalahti, Olli, Hepojoki, Jussi

المساهمون: Department of Virology, Veterinary Biosciences, HUSLAB

مصطلحات موضوعية: 11832 Microbiology and virology

وصف الملف: application/pdf

العلاقة: Rusanen , J , Kareinen , L , Szirovicza , L , Ugurlu , H , Levanov , L , Jääskeläinen , A , Ahava , M J , Kurkela , S , Saksela , K , Hedman , K , Vapalahti , O & Hepojoki , J 2021 , ' A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept ' , mBio , vol. 12 , no. 3 , e00902-21 . https://doi.org/10.1128/mBio.00902-21Test; ORCID: /0000-0003-1779-7960/work/107666807; ORCID: /0000-0001-5699-214X/work/107668578; ORCID: /0000-0003-0827-122X/work/107668962; ORCID: /0000-0003-2270-6824/work/107669947; ORCID: /0000-0002-3954-5118/work/107673794; ORCID: /0000-0003-1528-044X/work/107674518; ORCID: /0000-0002-3849-7847/work/107674617; ORCID: /0000-0001-6653-3238/work/107675102; ORCID: /0000-0003-2911-3212/work/155656130; http://hdl.handle.net/10138/339554Test; 2fff13d6-7c08-4841-9ca1-98abff1e8ea9; 000694797200015

الإتاحة: http://hdl.handle.net/10138/339554Test

المؤلفون: Rusanen, Juuso, Kareinen, Lauri, Szirovicza, Leonora, Uğurlu, Hasan, Levanov, Lev, Jääskeläinen, Anu, Ahava, Maarit, Kurkela, Satu, Saksela, Kalle, Hedman, Klaus, Vapalahti, Olli, Hepojoki, Jussi

المساهمون: Paraskevis, Dimitrios, Paraskevis, D ( Dimitrios )

المصدر: Rusanen, Juuso; Kareinen, Lauri; Szirovicza, Leonora; Uğurlu, Hasan; Levanov, Lev; Jääskeläinen, Anu; Ahava, Maarit; Kurkela, Satu; Saksela, Kalle; Hedman, Klaus; Vapalahti, Olli; Hepojoki, Jussi (2021). A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept. mBio, 12(3):e00902-21.

مصطلحات موضوعية: Institute of Veterinary Pathology, 570 Life sciences, biology, Virology, Microbiology

وصف الملف: application/pdf

العلاقة: https://www.zora.uzh.ch/id/eprint/209427/1/mbio.00902-21.pdfTest; urn:issn:2150-7511

الإتاحة: https://doi.org/10.5167/uzh-20942710.1128/mbio.00902-21Test
https://www.zora.uzh.ch/id/eprint/209427Test/
https://www.zora.uzh.ch/id/eprint/209427/1/mbio.00902-21.pdfTest

المؤلفون: Cantuti-Castelvetri, Ludovico, Ojha, Ravi, Pedro, Liliana D., Djannatian, Minou, Franz, Jonas, Kuivanen, Suvi, van der Meer, Franziska, Kallio, Katri, Kaya, Tugberk, Anastasina, Maria, Smura, Teemu, Levanov, Lev, Szirovicza, Leonora, Tobi, Allan, Kallio-Kokko, Hannimari, Österlund, Pamela, Joensuu, Merja, Meunier, Frederic A., Butcher, Sarah J., Winkler, Martin Sebastian, Mollenhauer, Brit, Helenius, Ari, Gokce, Ozgun, Teesalu, Tambet, Hepojoki, Jussi, Vapalahti, Olli, Stadelmann, Christine, Balistreri, Giuseppe, Simons, Mikael

المساهمون: Molecular and Integrative Biosciences Research Programme, Viral Zoonosis Research Unit, Department of Virology, Medicum, Macromolecular structure and function, Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, HUSLAB, Biosciences, Helsinki One Health (HOH), Veterinary Microbiology and Epidemiology, Veterinary Biosciences, Olli Pekka Vapalahti / Principal Investigator, Helsinki Institute of Sustainability Science (HELSUS)

مصطلحات موضوعية: VIRUS, PROTEIN, SPIKE, 11832 Microbiology and virology

وصف الملف: application/pdf

العلاقة: The work in Munich and Gottingen was supported by grants from the German Research Foundation (SPP2191, TRR128-2, TRR274-1, SyNergy Excellence Cluster, EXC2145, Projekt ID390857198, EXC 2067/1-390729940, and STA 1389/5-1), the ERC (Consolidator Grant to M.S.), and the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation. The work at the University of Helsinki was supported by the University of Helsinki and by donations from Finnish colleagues to whom we are very grateful. The Academy of Finland supported G.B. (318434), O. V. (336490), S.J.B. (315950 and 336471), and J.H. (1308613 and 1314119). O.V. was supported by Jane and Aatos Erkko Foundation, EU Horizon 2020 program VEO (874735), and Helsinki University Hospital Funds (TYH2018322). S.J.B. was supported by the Swedish Research Foundation and M.A. by the Marie Sklodowska-Curie Actions (799929). M.J. is supported by The Australian Research Council's Discovery Early Career Researcher Award (DE190100565). F.A. M. is supported by an Australian National Health and Medical Research Council Senior Research Fellowship (GNT1155794). T.T. and A.T. are supported by the European Regional Development Fund (project 2014-2020.4.01.15-0012), Wellcome Trust International Fellowship WT095077MA, European Research Council grant GLIOGUIDE, and the Estonian Research Council (grants PRG230 and EAG79 to T. T.).; Cantuti-Castelvetri , L , Ojha , R , Pedro , L D , Djannatian , M , Franz , J , Kuivanen , S , van der Meer , F , Kallio , K , Kaya , T , Anastasina , M , Smura , T , Levanov , L , Szirovicza , L , Tobi , A , Kallio-Kokko , H , Österlund , P , Joensuu , M , Meunier , F A , Butcher , S J , Winkler , M S , Mollenhauer , B , Helenius , A , Gokce , O , Teesalu , T , Hepojoki , J , Vapalahti , O , Stadelmann , C , Balistreri , G & Simons , M 2020 , ' Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity ' , Science , vol. 370 , no. 6518 . https://doi.org/10.1126/science.abd2985Test; ORCID: /0000-0001-5699-214X/work/86484143; ORCID: /0000-0003-2270-6824/work/86485391; ORCID: /0000-0001-7060-5871/work/86486103; ORCID: /0000-0003-1528-044X/work/86488085; 0b59c19a-6dd0-42c0-8e25-3a48425633b7; http://hdl.handle.net/10138/324014Test; 000590522900065

الإتاحة: http://hdl.handle.net/10138/324014Test