-
1دورية أكاديمية
المؤلفون: Christine Huynh, Swen Seeland, Jerome Segrestaa, Carmela Gnerre, Jens Hogeback, Henriette E. Meyer zu Schwabedissen, Jasper Dingemanse, Patricia N. Sidharta
المصدر: Frontiers in Pharmacology, Vol 13 (2022)
مصطلحات موضوعية: CXCR7, ADME, accelerator mass spectrometry, microtracer, CYP3A4, 14C-ACT-1004-1239, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2022.812065/fullTest; https://doaj.org/toc/1663-9812Test
-
2دورية أكاديمية
المؤلفون: Alexander Treiber, Stephane Delahaye, Swen Seeland, Carmela Gnerre
المصدر: Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
مصطلحات موضوعية: endothelin receptor antagonist, macitentan, P450 induction, species differences, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2052-1707Test
-
3دورية أكاديمية
المؤلفون: Alexander Treiber, Swen Seeland, Belal Haschimi, Aude Weigel, Jodi T. Williams, Jerome Gabillet
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Ecology, Marine Biology, Cancer, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, nivasorexant orexin metabolism metabolising enzymes excretion rat human
الإتاحة: https://doi.org/10.6084/m9.figshare.25324354.v1Test
https://figshare.com/articles/journal_contribution/The_metabolism_of_the_orexin-1_selective_receptor_antagonist_nivasorexant/25324354Test -
4
المؤلفون: Alexander Treiber, Stephane Delahaye, Aude Weigel, Päivi Aeänismaa, John Gatfield, Swen Seeland
المصدر: Xenobiotica. :1-11
مصطلحات موضوعية: Pharmacology, Health, Toxicology and Mutagenesis, General Medicine, Toxicology, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2930e1c9e76ec63d4baf47c3aa3dfedaTest
https://doi.org/10.1080/00498254.2023.2183159Test -
5
المؤلفون: Alexander Treiber, Hamed Aissaoui, Stéphane Delahaye, Sven Glutz, Julien Grimont, Claus Müller, Swen Seeland, Valérie Siefken, Christoph Boss
المصدر: ChemMedChem. 18
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::becc86a6b2e1fb82c9985bf2d82fe08eTest
https://doi.org/10.1002/cmdc.202300030Test -
6
المؤلفون: Christine, Huynh, Swen, Seeland, Jerome, Segrestaa, Carmela, Gnerre, Jens, Hogeback, Henriette E, Meyer Zu Schwabedissen, Jasper, Dingemanse, Patricia N, Sidharta
المصدر: Frontiers in pharmacology. 13
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::ccbd7b5b44b619c122e55eec640f8bacTest
https://pubmed.ncbi.nlm.nih.gov/35431953Test -
7
المؤلفون: Christine Huynh, Swen Seeland, Jerome Segrestaa, Carmela Gnerre, Jens Hogeback, Henriette E. Meyer zu Schwabedissen, Jasper Dingemanse, Patricia N. Sidharta
مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, CXCR7, ADME, accelerator mass spectrometry, microtracer, CYP3A4, 14C-ACT-1004-1239, first-in-human
الإتاحة: https://doi.org/10.3389/fphar.2022.812065.s001Test
https://figshare.com/articles/dataset/DataSheet1_Absorption_Metabolism_and_Excretion_of_ACT-1004-1239_a_First-In-Class_CXCR7_Antagonist_In_Vitro_Preclinical_and_Clinical_Data_docx/19459592Test -
8
المؤلفون: Peter Seiler, L. Jacob, Swen Seeland, S. Diethelm, N. Tidten-Luksch, Jean-Philippe Surivet, M. Wicki, Georg Rueedi, Jean-Luc Specklin, Michel Enderlin-Paput, Christian Hubschwerlen, Azely Mirre, R. Lange, G. Mathieu, Christine Schmitt, C. Herrmann, Philippe Panchaud, A.-C. Blumstein, A. Mac Sweeney, F. Masse, Daniel Ritz, Jean-Christophe Gauvin, Carmela Gnerre
المصدر: Journal of Medicinal Chemistry. 63:66-87
مصطلحات موضوعية: Gram-negative bacteria, Microbial Sensitivity Tests, Hydroxamic Acids, medicine.disease_cause, Amidohydrolases, In vivo, Gram-Negative Bacteria, Drug Discovery, Hydrolase, Escherichia coli, medicine, Animals, Pyrroles, Enzyme Inhibitors, Escherichia coli Infections, Mice, Inbred ICR, biology, Chemistry, Pseudomonas aeruginosa, biology.organism_classification, Enterobacteriaceae, In vitro, Anti-Bacterial Agents, Multiple drug resistance, Klebsiella pneumoniae, Biochemistry, Molecular Medicine, Female, Bacteria
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae4ad619b6cf3e0f3c6f741f71c0456Test
https://doi.org/10.1021/acs.jmedchem.9b01604Test -
9
المؤلفون: Michel Enderlin-Paput, Swen Seeland, A.-C. Blumstein, Daniel Ritz, Peter Seiler, R. Lange, Jean-Philippe Surivet, Christine Schmitt, F. Masse, Jean-Christophe Gauvin, S. Diethelm, L. Jacob, Charlyse Herrmann, Carmela Gnerre, Hans H. Locher, G. Mathieu, Azely Mirre, Georg Rueedi, Philippe Panchaud
المصدر: Journal of medicinal chemistry. 63(1)
مصطلحات موضوعية: Drug, media_common.quotation_subject, Microbial Sensitivity Tests, Pharmacology, Hydroxamic Acids, 01 natural sciences, Amidohydrolases, 03 medical and health sciences, Mice, In vivo, Drug Discovery, Gram-Negative Bacteria, Animals, Solubility, Enzyme Inhibitors, Lead (electronics), Escherichia coli Infections, 030304 developmental biology, media_common, 0303 health sciences, Molecular Structure, Chemistry, 0104 chemical sciences, Anti-Bacterial Agents, Rats, 010404 medicinal & biomolecular chemistry, Hepatocytes, Molecular Medicine, Administration, Intravenous
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8724e5d5a4339ed1cc3153b7f635fcc4Test
https://pubmed.ncbi.nlm.nih.gov/31804829Test -
10
المؤلفون: Swen Seeland, Jérôme Segrestaa, Alexander Treiber, Tommaso Miraval, Martin Bolli, Jacques-Alexis Funel
المصدر: Xenobiotica. 46:253-267
مصطلحات موضوعية: Endothelin Receptor Antagonists, Male, Ethylene Glycol, Health, Toxicology and Mutagenesis, Metabolite, Drug Evaluation, Preclinical, 030204 cardiovascular system & hematology, Pharmacology, Biology, Hydroxylation, Toxicology, 030226 pharmacology & pharmacy, Biochemistry, Excretion, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Animals, Rats, Wistar, Biotransformation, Chromatography, High Pressure Liquid, Sulfamide, Macitentan, Sulfonamides, Dose-Response Relationship, Drug, Endothelin receptor antagonist, General Medicine, Metabolism, Glucuronic acid, Rats, Glucose, Pyrimidines, chemistry, Hepatocytes, Microsomes, Liver, Female, Bile Ducts, Metabolic Networks and Pathways
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2646630edc04e9780ac18a81b99847fTest
https://doi.org/10.3109/00498254.2015.1070302Test