يعرض 1 - 10 نتائج من 10 نتيجة بحث عن '"Svenja Laue"', وقت الاستعلام: 1.71s تنقيح النتائج
  1. 1
    Sequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome

    المؤلفون: Stefanie Sudhop, Harald Lahm, Thomas Brade, Sharon L. Paige, Alexander Goedel, Svenja Laue, Thomas Meitinger, Markus Krane, Stefanie A. Doppler, Alessandra Moretti, Connie R. Bezzina, Pedro Schneider, Zhong Zhang, Makoto Sahara, Neil E. Bowles, Hilansi Rawat, Riccardo Berutti, Nazan Puluca, Ilaria My, Peter J. Gruber, Andreas Dendorfer, Ralf Gilsbach, Nora Lang, M. Dreßen, Christine M. Schneider, S. Schwarz, Daniel Sinnecker, I. Neb, Gianluca Santamaria, Karl-Ludwig Laugwitz, Rüdiger Lange, Sean M. Wu, Bruce D. Gelb, C. Abou-Ajram, Tatjana Dorn, Fleur V.Y. Tjong, Lia Crotti, Maria Rijlaarsdam, Matthias Mann, Christian Kupatt, Lutz Hein, Julie Cleuziou, Elisa Mastantuono, Lesca M. Holdt, Sophia Doll, Bernd H. Northoff

    المساهمون: Cardiology, ACS - Heart failure & arrhythmias, Krane, M, Dressen, M, Santamaria, G, My, I, Schneider, C, Dorn, T, Laue, S, Mastantuono, E, Berutti, R, Rawat, H, Gilsbach, R, Schneider, P, Lahm, H, Schwarz, S, Doppler, S, Paige, S, Puluca, N, Doll, S, Neb, I, Brade, T, Zhang, Z, Abou-Ajram, C, Northoff, B, Holdt, L, Sudhop, S, Sahara, M, Goedel, A, Dendorfer, A, Tjong, F, Rijlaarsdam, M, Cleuziou, J, Lang, N, Kupatt, C, Bezzina, C, Lange, R, Bowles, N, Mann, M, Gelb, B, Crotti, L, Hein, L, Meitinger, T, Wu, S, Sinnecker, D, Gruber, P, Laugwitz, K, Moretti, A

    المصدر: Circulation 144, 1409-1428 (2021)
    Circulation
    bioRxiv
    Circulation, 144(17), 1409-1428. Lippincott Williams and Wilkins

    مصطلحات موضوعية: Organogenesis, whole exome sequencing, Hypoplastic left heart syndrome, Pathogenesis, Transcriptome, 0302 clinical medicine, Original Research Articles, Induced pluripotent stem cell, Exome sequencing, 0303 health sciences, Heart development, Myogenesis, hypoplastic left heart syndrome, unfolded protein response, Cell cycle, heart defects, congenital, Hypoplasia, ddc, 3. Good health, Autophagy, Cell Cycle, Heart Defects, Congenital, Hypoplastic Left Heart Syndrome, Induced Pluripotent Stem Cells, Unfolded Protein Response, Whole Exome Sequencing, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Cardiology, Heart defects, cell cycle, medicine.symptom, Cardiology and Cardiovascular Medicine, autophagy, medicine.medical_specialty, induced pluripotent stem cells, Ventricular outflow tract obstruction, Biology, Genetic Heterogeneity, 03 medical and health sciences, Physiology (medical), Internal medicine, medicine, Humans, 030304 developmental biology, Lineage commitment, business.industry, Genetic heterogeneity, congenital, Human heart, medicine.disease, Unfolded protein response, Cancer research, business, 030217 neurology & neurosurgery

    وصف الملف: application/pdf; STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0de69ffa304c5f2a963a861f6f795cTest
    https://doi.org/10.1101/2021.04.24.441110Test


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  2. 2
    Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection

    المؤلفون: Kristin Raedecke, Karl-Ludwig Laugwitz, Johannes W.G. Janssen, Sebastian Clauss, Alessandra Moretti, Tatjana Dorn, Gudrun A. Rappold, Anna Jauch, Birgit Campbell, Svenja Laue, Simon Sumer, Sandra Hoffmann, Stefan Kääb, Viktoria Frajs

    المصدر: Stem Cell Reports

    مصطلحات موضوعية: 0301 basic medicine, Resource, Heterozygote, medicine.medical_treatment, Induced Pluripotent Stem Cells, Computational biology, Biology, medicine.disease_cause, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Genome editing, precise gene editing, patient-derived iPSCs, Atrial Fibrillation, Genetics, medicine, Humans, Digital polymerase chain reaction, Allele, Selection (genetic algorithm), Alleles, Gene Editing, Homeodomain Proteins, isogenic control, Mutation, Stochastic Processes, Base Sequence, business.industry, sib selection, High-Throughput Nucleotide Sequencing, Recombinational DNA Repair, Cell Biology, Stem-cell therapy, SHOX2, Cell sorting, 3. Good health, Clone Cells, 030104 developmental biology, Personalized medicine, Single-Cell Analysis, business, 030217 neurology & neurosurgery, Developmental Biology, RNA, Guide, Kinetoplastida

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d369d1bf132c8ebafa6c74bec45de6Test
    https://pubmed.ncbi.nlm.nih.gov/32976766Test


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  3. 3
    Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish

    المؤلفون: Monika Kustermann, Svenja Laue, Yinghong Cui, Douglas G. Tilley, Laurel A. Grisanti, Melanie Rothe, Michael Kauk, Carsten Hoffmann, Melanie Philipp, WH Zimmermann, Teresa Casar Tena, Allessandra Moretti, Farah Raad, Michael Kühl, Martina S. Burczyk, Sabrina Matysik, Martin D. Burkhalter, Cornelia Donow, Jürgen Wess

    المصدر: JCI Insight

    مصطلحات موضوعية: 0301 basic medicine, Embryo, Nonmammalian, Tolterodine Tartrate, Organogenesis, Muscarinic Antagonists, Mice, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Heart Conduction System, Muscarinic acetylcholine receptor, Heart rate, medicine, Animals, Humans, Myocytes, Cardiac, Receptor, Zebrafish, Mice, Knockout, Receptor, Muscarinic M3, Sinoatrial node, business.industry, fungi, Muscarinic acetylcholine receptor M3, Arrhythmias, Cardiac, General Medicine, Embryo, Mammalian, medicine.disease, 3. Good health, Disease Models, Animal, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Heart failure, Atrioventricular canal, Electrical conduction system of the heart, business, Neuroscience, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d95a3d11c2efe67a92a1fc8c1ec423aTest
    https://doi.org/10.1172/jci.insight.121971Test


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  4. 4
    Identification of Differentially Regulated Pathways in Cardiac Development and Cardiac Gene Expression during In Vitro Cardiac Differentiation of HLHS-derived Human Induced Pluripotent Stem Cells using Transcriptome Analysis

    المؤلفون: Zuwen Zhang, M. Dreßen, Bernd H. Northoff, Lesca M. Holdt, Ruediger Lange, K L Laugwitz, Markus Krane, I. Neb, Stefanie A. Doppler, Svenja Laue, Daniel Teupser, Harald Lahm, A. Gödel, Alessandra Moretti, Marcus-André Deutsch

    المصدر: The Thoracic and Cardiovascular Surgeon. 66:S1-S110

    مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Transcriptome, business.industry, Cardiac differentiation, Gene expression, Medicine, Surgery, Identification (biology), Human Induced Pluripotent Stem Cells, Cardiology and Cardiovascular Medicine, business, In vitro, Cell biology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a3ae6f4f2552eba95c89c6b5ebc426aTest
    https://doi.org/10.1055/s-0038-1628043Test


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  5. 5
    P1848Primary cilium-autophagy-cell cycle axis defects impair cardiac progenitor specification in hypoplastic left heart syndrome

    المؤلفون: M Dressen, Alessandra Moretti, Markus Krane, Ilaria My, F Schmidt, K L Laugwitz, H Lickert, H Lahm, Tatjana Dorn, Svenja Laue, Alexander Goedel, Thomas Brade

    المصدر: European Heart Journal. 39

    مصطلحات موضوعية: Pathology, medicine.medical_specialty, Cardiac progenitors, business.industry, Cilium, Autophagy, Medicine, Cell cycle, Cardiology and Cardiovascular Medicine, business, medicine.disease, Hypoplastic left heart syndrome

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b173e64103cda613f52650d82f259e4eTest
    https://doi.org/10.1093/eurheartj/ehy565.p1848Test


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  6. 6
    Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity

    المؤلفون: Christian Baarlink, Elisabeth Graf, Karl-Ludwig Laugwitz, Tatjana Dorn, Giovanni Cuda, Christian Kupatt, Thomas Meitinger, Elisa Mastantuono, Andrew A. Grace, Dorota M Zawada, Ilaria My, Stefan Kääb, Elvira Immacolata Parrotta, Jessica Kornherr, Austin Smith, Laura Iop, Ralf J. Dirschinger, Gianluca Santamaria, Robert Grosse, Alexander Goedel, Harold Ayetey, Rabea Hinkel, Alessandra Moretti, Daniel Sinnecker, Tarik Bozoglu, Svenja Laue, Tilman Ziegler

    المساهمون: Smith, Austin [0000-0002-3029-4682], Apollo - University of Cambridge Repository

    المصدر: The EMBO Journal

    مصطلحات موضوعية: 0301 basic medicine, Genetics and Molecular Biology (all), RHOA, Immunology and Microbiology (all), Cell Communication, Mice, SCID, Biochemistry, Mechanotransduction, Cellular, Cardiac fat, Cardiac progenitors, Lineage conversion, MRTF/SRF, RhoA/ROCK signaling, Neuroscience (all), Molecular Biology, Biochemistry, Genetics and Molecular Biology (all), Mice, 0302 clinical medicine, cardiac progenitors, Myocytes, Cardiac, Adipogenesis, Heart development, biology, General Neuroscience, Stem Cells, Cardiac muscle, Cell Differentiation, Articles, cardiac fat, Cell biology, medicine.anatomical_structure, LIM-Homeodomain Proteins, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Fate mapping, medicine, Animals, Humans, WT1 Proteins, Gene, General Immunology and Microbiology, Actin cytoskeleton, 030104 developmental biology, Gene Expression Regulation, lineage conversion, ISL1, biology.protein, Trans-Activators, Cell Adhesion, Polarity & Cytoskeleton, rhoA GTP-Binding Protein, Development & Differentiation, 030217 neurology & neurosurgery, Homeostasis, Transcription Factors

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f9a5c5b5a3247bc2a7ceb0878281a0Test
    https://www.repository.cam.ac.uk/handle/1810/280257Test


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  7. 7
    The DPP-4 Inhibitor Linagliptin Restores β-Cell Function and Survival in Human Isolated Islets Through GLP-1 Stabilization

    المؤلفون: François Pattou, Gitanjali Dharmadhikari, Julie Kerr-Conte, Svenja Laue, Payal Shah, Desiree M. Schumann, Kathrin Maedler, Thomas Klein, Amin Ardestani

    المصدر: The Journal of Clinical Endocrinology & Metabolism. 98:E1163-E1172

    مصطلحات موضوعية: medicine.medical_specialty, Drug Inverse Agonism, Cell Survival, medicine.drug_class, Dipeptidyl Peptidase 4, Endocrinology, Diabetes and Metabolism, Interleukin-1beta, Clinical Biochemistry, Palmitic Acid, Linagliptin, Biochemistry, Antioxidants, Sitagliptin Phosphate, Tissue Culture Techniques, chemistry.chemical_compound, Endocrinology, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Diabetes mellitus, Internal medicine, Insulin Secretion, medicine, Humans, Insulin, Dipeptidyl peptidase-4, Dipeptidyl-Peptidase IV Inhibitors, geography, geography.geographical_feature_category, Protein Stability, Nitrotyrosine, Anti-Inflammatory Agents, Non-Steroidal, Biochemistry (medical), Triazoles, Receptor antagonist, medicine.disease, Islet, Glucagon-like peptide-1, Peptide Fragments, Recombinant Proteins, Interleukin 1 Receptor Antagonist Protein, chemistry, Purines, Pyrazines, Quinazolines, Cytokines, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332788995ee1104a7817a330e5e999acTest
    https://doi.org/10.1210/jc.2013-1029Test


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  8. 8
    cCMP is a substrate for MRP5

    المؤلفون: Roland Seifert, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel, Volkhard Kaever, Svenja Laue, Moritz Winterhoff

    المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology, 387, 9, pp. 893-5
    Naunyn-Schmiedeberg's Archives of Pharmacology, 387, 893-5

    مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Pyrimidine, CCMP, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Phosphodiesterase, Biological Transport, General Medicine, Biology, chemistry.chemical_compound, Cytosol, Cyclic nucleotide, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], HEK293 Cells, chemistry, Biochemistry, Second messenger system, Extracellular, Humans, Nucleotide, Multidrug Resistance-Associated Proteins, Nucleotides, Cyclic

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f05f009f14294113f06a6d6bade3c3Test
    https://doi.org/10.1007/s00210-014-1018-9Test


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  9. 9
    The DPP-4 inhibitor linagliptin restores \u03b2-cell function & survival in human isolated islets through GLP-1 stabilization

    المؤلفون: Payal Shah, Amin Ardestani, Gitanjali Dharmadhikari, Svenja Laue, Desiree M. Schumann, Julie Kerr-Conte, Francois Pattout, Thomas Klein, Kathrin Maedler

    المصدر: JCEM.

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=erc_________::78d549df6c017102f64ffe5b0574da03Test


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  10. 10
    TOSO promotes β-cell proliferation and protects from apoptosis

    المؤلفون: Fabienne T. Schulthess, Jose Oberholzer, Gitanjali Dharmadhikari, M. Mühle, Kathrin Maedler, Julie Kerr-Conte, Svenja Laue, François Pattou

    المصدر: Molecular metabolism. 1(1-2)

    مصطلحات موضوعية: geography, geography.geographical_feature_category, Cell growth, business.industry, Regulator, Cell Biology, Caspase 8, Inhibitory postsynaptic potential, Islet, Pathophysiology, Cell biology, Downregulation and upregulation, Apoptosis, Immunology, Medicine, Original Article, business, Molecular Biology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970e0017b6c5f2d2e21b9662fc7c30e1Test
    https://pubmed.ncbi.nlm.nih.gov/24024120Test


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