المؤلفون: Bernhard M Kaess, Maciej Tomaszewski, Peter S Braund, Klaus Stark, Suzanne Rafelt, Marcus Fischer, Robert Hardwick, Christopher P Nelson, Radoslaw Debiec, Fritz Huber, Werner Kremer, Hans Robert Kalbitzer, Lynda M Rose, Daniel I Chasman, Jemma Hopewell, Robert Clarke, Paul R Burton, Martin D Tobin, Christian Hengstenberg, Nilesh J Samani

المصدر: PLoS ONE, Vol 6, Iss 1, p e14529 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC3024972?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/db13f5b5561b4858acda2f46a8bfd058Test

المؤلفون: Corneliu A. Bodea, Benjamin M. Neale, Stephan Ripke, Mark J. Daly, Bernie Devlin, Kathryn Roeder, Murray Barclay, Laurent Peyrin-Biroulet, Mathias Chamaillard, Jean-Frederick Colombel, Mario Cottone, Anthony Croft, Renata D’Incà, Jonas Halfvarson, Katherine Hanigan, Paul Henderson, Jean-Pierre Hugot, Amir Karban, Nicholas A. Kennedy, Mohammed Azam Khan, Marc Lémann, Arie Levine, Dunecan Massey, Monica Milla, Grant W. Montgomery, Sok Meng Evelyn Ng, Ioannis Oikonomou, Harald Peeters, Deborah D. Proctor, Jean-Francois Rahier, Rebecca Roberts, Paul Rutgeerts, Frank Seibold, Laura Stronati, Kirstin M. Taylor, Leif Törkvist, Kullak Ublick, Johan Van Limbergen, Andre Van Gossum, Morten H. Vatn, Hu Zhang, Wei Zhang, Jane M. Andrews, Peter A. Bampton, Timothy H. Florin, Richard Gearry, Krupa Krishnaprasad, Ian C. Lawrance, Gillian Mahy, Graham Radford-Smith, Rebecca L. Roberts, Lisa A. Simms, Leila Amininijad, Isabelle Cleynen, Olivier Dewit, Denis Franchimont, Michel Georges, Debby Laukens, Emilie Theatre, André Van Gossum, Severine Vermeire, Guy Aumais, Leonard Baidoo, Arthur M. Barrie, Karen Beck, Edmond-Jean Bernard, David G. Binion, Alain Bitton, Steve R. Brant, Judy H. Cho, Albert Cohen, Kenneth Croitoru, Lisa W. Datta, Colette Deslandres, Richard H. Duerr, Debra Dutridge, John Ferguson, Joann Fultz, Philippe Goyette, Gordon R. Greenberg, Talin Haritunians, Gilles Jobin, Seymour Katz, Raymond G. Lahaie, Dermot P. McGovern, Linda Nelson, Sok Meng Ng, Kaida Ning, Pierre Paré, Miguel D. Regueiro, John D. Rioux, Elizabeth Ruggiero, L. Philip Schumm, Marc Schwartz, Regan Scott, Yashoda Sharma, Mark S. Silverberg, Denise Spears, A. Hillary Steinhart, Joanne M. Stempak, Jason M. Swoger, Constantina Tsagarelis, Clarence Zhang, Hongyu Zhao, Jan Aerts, Tariq Ahmad, Hazel Arbury, Anthony Attwood, Adam Auton, Stephen G. Ball, Anthony J. Balmforth, Chris Barnes, Jeffrey C. Barrett, Inês Barroso, Anne Barton, Amanda J. Bennett, Sanjeev Bhaskar, Katarzyna Blaszczyk, John Bowes, Oliver J. Brand, Peter S. Braund, Francesca Bredin, Gerome Breen, Morris J. Brown, Ian N. Bruce, Jaswinder Bull, Oliver S. Burren, John Burton, Jake Byrnes, Sian Caesar, Niall Cardin, Chris M. Clee, Alison J. Coffey, John M.C. Connell, Donald F. Conrad, Jason D. Cooper, Anna F. Dominiczak, Kate Downes, Hazel E. Drummond, Darshna Dudakia, Andrew Dunham, Bernadette Ebbs, Diana Eccles, Sarah Edkins, Cathryn Edwards, Anna Elliot, Paul Emery, David M. Evans, Gareth Evans, Steve Eyre, Anne Farmer, Nicol Ferrier, Edward Flynn, Alistair Forbes, Liz Forty, Jayne A. Franklyn, Timothy M. Frayling, Rachel M. Freathy, Eleni Giannoulatou, Polly Gibbs, Paul Gilbert, Katherine Gordon-Smith, Emma Gray, Elaine Green, Chris J. Groves, Detelina Grozeva, Rhian Gwilliam, Anita Hall, Naomi Hammond, Matt Hardy, Pile Harrison, Neelam Hassanali, Husam Hebaishi, Sarah Hines, Anne Hinks, Graham A. Hitman, Lynne Hocking, Chris Holmes, Eleanor Howard, Philip Howard, Joanna M.M. Howson, Debbie Hughes, Sarah Hunt, John D. Isaacs, Mahim Jain, Derek P. Jewell, Toby Johnson, Jennifer D. Jolley, Ian R. Jones, Lisa A. Jones, George Kirov, Cordelia F. Langford, Hana Lango-Allen, G. Mark Lathrop, James Lee, Kate L. Lee, Charlie Lees, Kevin Lewis, Cecilia M. Lindgren, Meeta Maisuria-Armer, Julian Maller, John Mansfield, Jonathan L. Marchini, Paul Martin, Dunecan C.O. Massey, Wendy L. McArdle, Peter McGuffin, Kirsten E. McLay, Gil McVean, Alex Mentzer, Michael L. Mimmack, Ann E. Morgan, Andrew P. Morris, Craig Mowat, Patricia B. Munroe, Simon Myers, William Newman, Elaine R. Nimmo, Michael C. O’Donovan, Abiodun Onipinla, Nigel R. Ovington, Michael J. Owen, Kimmo Palin, Aarno Palotie, Kirstie Parnell, Richard Pearson, David Pernet, John R.B. Perry, Anne Phillips, Vincent Plagnol, Natalie J. Prescott, Inga Prokopenko, Michael A. Quail, Suzanne Rafelt, Nigel W. Rayner, David M. Reid, Anthony Renwick, Susan M. Ring, Neil Robertson, Samuel Robson, Ellie Russell, David St Clair, Jennifer G. Sambrook, Jeremy D. Sanderson, Stephen J. Sawcer, Helen Schuilenburg, Carol E. Scott, Richard Scott, Sheila Seal, Sue Shaw-Hawkins, Beverley M. Shields, Matthew J. Simmonds, Debbie J. Smyth, Elilan Somaskantharajah, Katarina Spanova, Sophia Steer, Jonathan Stephens, Helen E. Stevens, Kathy Stirrups, Millicent A. Stone, David P. Strachan, Zhan Su, Deborah P.M. Symmons, John R. Thompson, Wendy Thomson, Martin D. Tobin, Mary E. Travers, Clare Turnbull, Damjan Vukcevic, Louise V. Wain, Mark Walker, Neil M. Walker, Chris Wallace, Margaret Warren-Perry, Nicholas A. Watkins, John Webster, Michael N. Weedon, Anthony G. Wilson, Matthew Woodburn, B. Paul Wordsworth, Chris Yau, Allan H. Young, Eleftheria Zeggini, Matthew A. Brown, Paul R. Burton, Mark J. Caulfield, Alastair Compston, Martin Farrall, Stephen C.L. Gough, Alistair S. Hall, Andrew T. Hattersley, Adrian V.S. Hill, Christopher G. Mathew, Marcus Pembrey, Jack Satsangi, Michael R. Stratton, Jane Worthington, Matthew E. Hurles, Audrey Duncanson, Willem H. Ouwehand, Miles Parkes, Nazneen Rahman, John A. Todd, Nilesh J. Samani, Dominic P. Kwiatkowski, Mark I. McCarthy, Nick Craddock, Panos Deloukas, Peter Donnelly, Jenefer M. Blackwell, Elvira Bramon, Juan P. Casas, Aiden Corvin, Janusz Jankowski, Hugh S. Markus, Colin N.A. Palmer, Robert Plomin, Anna Rautanen, Richard C. Trembath, Ananth C. Viswanathan, Nicholas W. Wood, Chris C.A. Spencer, Gavin Band, Céline Bellenguez, Colin Freeman, Garrett Hellenthal, Matti Pirinen, Amy Strange, Hannah Blackburn, Suzannah J. Bumpstead, Serge Dronov, Matthew Gillman, Alagurevathi Jayakumar, Owen T. McCann, Jennifer Liddle, Simon C. Potter, Radhi Ravindrarajah, Michelle Ricketts, Matthew Waller, Paul Weston, Sara Widaa, Pamela Whittaker

المساهمون: UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (MGD) Service de gastro-entérologie, Institute for Molecular Medicine Finland, Aarno Palotie / Principal Investigator, Genomics of Neurological and Neuropsychiatric Disorders

المصدر: American journal of human genetics, Vol. 98, no. 5, p. 857-868 (2016)

مصطلحات موضوعية: 0301 basic medicine, Heredity, Genetics, Genetics (clinical), Computer science, Genetic Linkage, Genome-wide association study, VARIANTS, 030105 genetics & heredity, computer.software_genre, Bayes' theorem, Gene Frequency, HISTORY, IMPUTATION, False positive paradox, Genetics(clinical), Disease, 0303 health sciences, education.field_of_study, 030305 genetics & heredity, Inheritance (genetic algorithm), Genotype, DATABASE, Genetic genealogy, POWER, Population, Genomics, POPULATION STRATIFICATION, Biology, INHERITANCE, Population stratification, Machine learning, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Humans, Genetic Predisposition to Disease, GENOME-WIDE ASSOCIATION, education, Allele frequency, FAMILY-BASED ASSOCIATION, 030304 developmental biology, Genetic association, business.industry, Bayes Theorem, DISEASE ASSOCIATION, Human genetics, Hierarchical clustering, Genetics, Population, 030104 developmental biology, Case-Control Studies, 3111 Biomedicine, Artificial intelligence, business, computer, Software, Imputation (genetics)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a716d5c3b5025121394e710e95819952Test
https://doi.org/10.1016/j.ajhg.2016.02.025Test

المؤلفون: Bernhard O. Boehm, Marten H. Hofker, Clara C. Elbers, Sam E. Tischfield, Yvonne T. van der Schouw, Richa Saxena, Caitrin W. McDonough, Kandice Kottke-Marchant, Folkert W. Asselbergs, Heribert Schunkert, L. Adrienne Cupples, Nicole L. Glazer, Philippa J. Talmud, John G. Gums, Wolfgang Koenig, Debbie A Lawlor, Matthew B. Lanktree, Myriam Fornage, Andrea Z. LaCroix, A. H. Zwinderman, Alice V. Stanton, Ronald P. Stolk, Kristian M. Bailey, Jeffery R. O'Connell, James S. Pankow, Jolanda M. A. Boer, Brendan J. Keating, Alan R. Shuldiner, Christian Hengstenberg, Yun Li, Olle Melander, Christian Delles, Gail P. Jarvik, John Whitfield, Stephen Newhouse, Rita P.S. Middelberg, Winfried März, Arthur A.M. Wilde, Patricia B. Munroe, Yan Gong, Herman A. Taylor, Denis C. Shields, Hugh Watkins, Ronald Klein, Charles Kooperberg, Hans L. Hillege, Elina Toskala, Christie M. Ballantyne, Mingyao Li, Suzanne Rafelt, Nilesh J. Samani, Bruce H. R. Wolffenbuttel, Kent R. Bailey, Pieter A. Doevendans, Yii-Der Ida Chen, Jens Baumert, Peter Sever, Vinicius Tragante, Florianne Bauer, Sonia S. Anand, W. M. Monique Verschuren, Braxton D. Mitchell, Barbara Thorand, Daniel I. Swerdlow, Jonathan A. Shaffer, Barbara E.K. Klein, Kiang Liu, Michael Y. Tsai, Neil R Poulter, Nicholas J. Schork, Simon P. R. Romaine, Bernhard M. Kaess, Mark J. Caulfield, Wei Chen, Erin N. Smith, Connie R. Bezzina, Stephen S. Rich, Tushar Bhangale, Leslie A. Lange, Mika Kivimäki, John Barnard, Julie A. Johnson, Roy L. Silverstein, Daichi Shimbo, Yiran Guo, Jessica van Setten, Meena Kumari, Berta Almoguera, Claire E. Hastie, Marcus E. Kleber, Robert A. Hegele, Mieke D. Trip, Matthijs F.L. Meijs, Bruce M. Psaty, Tina Shah, Susan Redline, Eric Boerwinkle, Cisca Wijmenga, Jonas S. Dejong, Catharina A. Hartman, Karen J. Cruickshanks, Taimour Y. Langaee, Amber A. Burt, Niek Verweij, David Duggan, Jerome I. Rotter, Ellen Van Der Schoot, Sathanur R. Srinivasan, N. Charlotte Onland-Moret, Paul Burton, Hakon Hakonarson, Laya Mallela, Fotios Drenos, Yolande Appelman, Rhonda M. Cooper-DeHoff, Peter S. Braund, Eric J. Topol, Michael V. Holmes, Grant W. Montgomery, Hubert Scharnagl, Alexander P. Reiner, Susan Kirkland, Daniel J. Rader, John C. Whittaker, Clement E. Furlong, Suthesh Sivapalaratnam, Gerald S. Berenson, Kiran Musunuru, Steve E. Humphries, Toby Johnson, Sarah S. Murray, Ramakrishnan Rajagopalan, Paul I.W. de Bakker, Erik P A Van Iperen, John J.P. Kastelein, Robert Clarke, Jemma C. Hopewell, Thomas Illig, Wendy S. Post, Anna F. Dominiczak, Christopher P. Nelson, Amber L. Beitelshees, Gurunathan Murugesan, Pim van der Harst, G. Kees Hovingh, Muredach P. Reilly, Karina W. Davidson, John M. C. Connell, Anthony J. Balmforth, James G. Wilson, Jose M. Ordovas, Sarah G. Buxbaum, Tom R. Gaunt, Jana V. van Vliet-Ostaptchouk, Li Zhang, Peter J. van der Most, Ian N. M. Day, Willem H. Ouwehand, Salim Yusuf, Haiqing Shen, Sekar Kathiresan, Nathan Pankratz, Sandosh Padmanabhan, Pamela J. Schreiner, Alistair S. Hall, Juan P. Casas, Nicholas G. Martin, Joost L. Van Pelt, Kelly A. Volcik, Aroon D. Hingorani

المساهمون: Cardiology, ICaR - Heartfailure and pulmonary arterial hypertension, Faculteit Medische Wetenschappen/UMCG, Life Course Epidemiology (LCE), Lifestyle Medicine (LM), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), Center for Liver, Digestive and Metabolic Diseases (CLDM), Vascular Ageing Programme (VAP), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), APH - Amsterdam Public Health, Epidemiology and Data Science, Graduate School, Vascular Medicine, ACS - Amsterdam Cardiovascular Sciences, Landsteiner Laboratory, Clinical Haematology

المصدر: The American Journal of Human Genetics; Vol 91
American journal of human genetics, 91(5), 823-838. Cell Press
American journal of human genetics, vol 91, iss 5
The American Journal of Human Genetics
American Journal of Human Genetics, 91(5), 823-838. CELL PRESS
Asselbergs, F W, Guo, Y R, van Iperen, E P A, Sivapalaratnam, S, Tragante, V, Lanktree, M B, Lange, L A, Almoguera, B, Appelman, J E A, Barnard, J, Baumert, J, Beitelshees, A L, Bhangale, T R, Chen, Y D I, Gaunt, T R, Gong, Y, Hopewell, J C, Johnson, T, Kleber, M E, Langaee, T Y, Li, M Y, Li, Y R, Liu, K A, McDonough, C W, Meijs, M E, Middelberg, R P S, Musunuru, K, Nelson, C P, O'Connell, J R, Padmanabhan, S, Pankow, J S, Pankratz, N, Rafelt, S, Rajagopalan, R, Romaine, S P R, Schork, N J, Shaffer, J, Shen, H Q, Smith, E N, Tischfield, S E, van der Most, P J, van Vliet-Ostaptchouk, J V, Verweij, N, Volcik, K A, Zhang, L, Bailey, K R, Bailey, K M, Bauer, F, Boer, J M A, Braund, P S, Burt, A, Burton, P R, Buxbaum, S G, Chen, W, Cooper-DeHoff, R M, Cupples, L A, deJong, J S, Delles, C, Duggan, D, Fornage, M, Furlong, C E, Glazer, N, Gums, J G, Hastie, C, Holmes, M V, Illig, T, Kirkland, S A, Kivimaki, M, Klein, R, Klein, B E, Kooperberg, C, Kottke-Marchant, K, Kumari, M, LaCroix, A Z, Mallela, L, Murugesan, G, Ordovas, J, Ouwehand, W H, Post, W S, Saxena, R, Scharnagl, H, Schreiner, P J, Shah, T, Shields, D C, Shimbo, D, Srinivasan, S R, Stolk, R P, Swerdlow, D I, Taylor, H A, Topo, E J, Toskala, E, van Pelt, J L, van Setten, J, Yusuf, S, Whittaker, J C, Zwinderman, A H, Anand, S S, Balmforth, A J & Berenson, G S 2012, ' Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci ', American journal of human genetics, vol. 91, no. 5, pp. 823-838 . https://doi.org/10.1016/j.ajhg.2012.08.032Test

مصطلحات موضوعية: Male, Candidate gene, Genome-wide association study, 030204 cardiovascular system & hematology, Cardiovascular, Medical and Health Sciences, 0302 clinical medicine, APOLIPOPROTEIN B-100, Missing heritability problem, MISSING HERITABILITY, 2.1 Biological and endogenous factors, Genetics(clinical), Aetiology, FAMILIAL HYPERCHOLESTEROLEMIA, Genetics (clinical), Genetics, Genetics & Heredity, 0303 health sciences, QUANTITATIVE TRAITS, Single Nucleotide, Biological Sciences, Lipids, 3. Good health, SNP genotyping, PLASMA TRIGLYCERIDES, Cholesterol, Phenotype, DENSITY-LIPOPROTEIN CHOLESTEROL, lipids (amino acids, peptides, and proteins), Female, HDL, Genotype, European Continental Ancestry Group, Quantitative Trait Loci, Single-nucleotide polymorphism, STATISTICAL-MODEL, Biology, Quantitative trait locus, Polymorphism, Single Nucleotide, Article, White People, LDL, 03 medical and health sciences, Sex Factors, Humans, CORONARY-HEART-DISEASE, Polymorphism, GENOME-WIDE ASSOCIATION, Genotyping, Triglycerides, 030304 developmental biology, Genetic association, COMPLEX TRAITS, Human Genome, Cholesterol, HDL, nutritional and metabolic diseases, Cholesterol, LDL, Atherosclerosis, LifeLines Cohort Study, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02b6baaa96ab2171c7cfc601d382898Test
https://doi.org/10.1016/j.ajhg.2012.08.032Test

المؤلفون: Morris J. Brown, Sanjeev S. Bhaskar, Alison J. Coffey, Suzanne Rafelt, Kirsten McLay, John Bowes, Francesca Bredin, Alastair Compston, John C. Mansfield, Elaine R. Nimmo, Kate Downes, Peter McGuffin, Neil Walker, Anthony J. Balmforth, Philip Howard, Detelina Grozeva, Helen Stevens, Kate L. Lee, Richard D. Pearson, Gerome Breen, T. Daniel Andrews, Sheila Seal, Anna Elliot, Beverley M. Shields, Andrew T. Hattersley, Sarah Edkins, Ann E. Morgan, Gil McVean, Julian Maller, Millicent A. Stone, Adam Auton, Carol Scott, Michael R. Stratton, Matthew Woodburn, John R. B. Perry, Michael Conlon O'Donovan, Nigel P. Carter, Vincent Plagnol, Stephen Sawcer, Sarah Hines, Mahim Jain, Allan H. Young, Steve Eyre, Elilan Somaskantharajah, Alexander J. Mentzer, Niall Cardin, Eleanor Howard, Inês Barroso, Stephen C. L. Gough, Toby Johnson, Deborah P M Symmons, Christopher Holmes, David St Clair, Patricia B. Munroe, Sue Shaw-Hawkins, Emma Gray, Stephen W. Scherer, Tariq Ahmad, Jaswinder Bull, Debbie Hughes, E. Russell, Timothy M. Frayling, Chris Clee, I. Nicol Ferrier, James Lee, Dominic P. Kwiatkowski, Husam Hebaishi, Anne Hinks, Simon Myers, Gareth Evans, Eleftheria Zeggini, Katarina Spanova, Michael L. Mimmack, David M. Reid, Amanda J. Bennett, Richard T. Scott, Armand Valsesia, Derek P. Jewell, Andrew P. Morris, Peter Donnelly, Mark J. Caulfield, Jake K. Byrnes, Lars Feuk, Pile Harrison, Anna F. Dominiczak, Cathryn Edwards, Andrew Dunham, Dalila Pinto, Inga Prokopenko, Ian Jones, Craig Mowat, Nigel R. Ovington, Willem H. Ouwehand, Edward Flynn, Jason D. Cooper, Louise V. Wain, Alistair Forbes, Bernadette Ebbs, Jennifer Jolley, Jonathan Marchini, Peter S. Braund, Ifejinelo Onyiah, Mark Walker, Adrian V. S. Hill, Cordelia Langford, Anne M. Phillips, George Kirov, David P. Strachan, Oliver S. Burren, Martin D. Tobin, Anthony G. Wilson, Ian N. Bruce, Hana Lango-Allen, Alistair S. Hall, Natalie J. Prescott, Charles Lee, Clare Turnbull, Cecilia M. Lindgren, John D. Isaacs, Jack Satsangi, Liz Forty, John M. C. Connell, Neelam Hassanali, Hazel E. Drummond, Matthew A. Brown, John A. Todd, Joanna M. M. Howson, Jennifer G. Sambrook, Graham A. Hitman, Michael N. Weedon, Christopher Yau, Abiodun Onipinla, Kathy Stirrups, Chris Tyler-Smith, Darshna Dudakia, G. Mark Lathrop, Katherine Gordon-Smith, Nazneen Rahman, Christopher J. Groves, William G. Newman, Kirstie Parnell, Stephen G. Ball, Tomas W Fitzgerald, Paul Gilbert, Kevin Lewis, Charlie W. Lees, Polly Gibbs, Rachel M. Freathy, Aarno Palotie, Katarzyna Blaszczyk, Matthew E. Hurles, Jonathan Stephens, Lynne J. Hocking, Nicholas A. Watkins, Christopher G. Mathew, Helen Schuilenburg, David Pernet, Eleni Giannoulatou, Kimmo Palin, Nigel W. Rayner, Donald F. Conrad, Susan M. Ring, John R. Thompson, Debbie J. Smyth, Wendy L. McArdle, B. Paul Wordsworth, David M. Evans, Dunecan Massey, Naomi Hammond, Diana Eccles, Panos Deloukas, Sian Caesar, Chris P. Barnes, Sophia Steer, Anthony Attwood, Chris Wallace, Richard Redon, Paul Burton, Anne Barton, Marcus Pembrey, Michael John Owen, Jane Worthington, Mary E. Travers, Jeremy D. Sanderson, Meeta Maisuria-Armer, Elaine K. Green, Michael A. Quail, Oliver J. Brand, Anne Farmer, Matthew J. Simmonds, Neil Robertson, Nicholas John Craddock, Zhan Su, Jan Aerts, Martin Farrall, Hazel Arbury, Damjan Vukcevic, Paul Emery, Omer Gokumen, A Hall, Wendy Thomson, Jeffrey C. Barrett, Margaret Warren-Perry, Rhian Gwilliam, Sarah E. Hunt, Samuel Robson, Paul Martin, Audrey Duncanson, Anthony Renwick, John Webster, Lisa Jones, Mark I. McCarthy, Nilesh J. Samani, Matthew Hardy, Miles Parkes, John Burton, Jayne A. Franklyn

المساهمون: Institut de Génomique d'Evry (IG), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department of Statistics [Oxford], University of Oxford, The Wellcome Trust Centre for Human Genetics [Oxford], The Wellcome Trust Case Control Consortium, Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, University of Oxford [Oxford], Medical Research Council (MRC)

المصدر: Nature
Nature, 2010, 464 (7289), pp.713-720. ⟨10.1038/nature08979⟩
Nature, Nature Publishing Group, 2010, 464 (7289), pp.713-720. ⟨10.1038/nature08979⟩
U86

مصطلحات موضوعية: endocrine system diseases, [SDV]Life Sciences [q-bio], Genome-wide association study, Pilot Projects, CCL3L1, SUSCEPTIBILITY, Arthritis, Rheumatoid, Diabetes mellitus genetics, 0302 clinical medicine, Crohn Disease, Gene Frequency, DUPLICATIONS, SCHIZOPHRENIA, Disease, Copy-number variation, Oligonucleotide Array Sequence Analysis, Genetics, 0303 health sciences, Multidisciplinary, PSORIASIS, HERITABILITY, LARGE-SCALE, Nucleic Acid Hybridization, Science & Technology - Other Topics, Wellcome Trust Case Control Consortium, Quality Control, DNA Copy Number Variations, General Science & Technology, Single-nucleotide polymorphism, COPY-NUMBER VARIATION, Biology, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, MD Multidisciplinary, mental disorders, Genetic predisposition, Diabetes Mellitus, SNP, Humans, Genetic Predisposition to Disease, Allele frequency, POLYMORPHISMS, 030304 developmental biology, Genetic association, Science & Technology, MULTIDISCIPLINARY SCIENCES, DELETION, C431 Medical Genetics, Case-Control Studies, 030217 neurology & neurosurgery, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabf06404a0287e631ec3785ace540b3Test
https://doi.org/10.1038/nature08979Test

المؤلفون: Benjamin F. Voight, Andrew D. Morris, G. Kees Hovingh, Anthony J. Balmforth, Hanneke Basart, Alistair S. Hall, Dominique Gauguier, Bok Ghee Han, Martina Müller-Nurasyid, Sarah Parish, Jarmo Virtamo, Christa Meisinger, Peter Wagner, George Dedoussis, Philipp S. Wild, Kari Stefansson, Jean-Baptiste Cazier, Kathleen Stirrups, Jiyoung Lee, Adrienne Cupples, Stavroula Kanoni, Danish Saleheen, Christian Hengstenberg, Svati H. Shah, Panos Deloukas, Anuj Goel, Stefan Blankenberg, Sian Tsung Tan, Alison H. Goodall, Tõnu Esko, Eric Boerwinkle, Gudmundur Thorgeirsson, Peter S. Braund, Joshua W. Knowles, Olle Melander, C. Ellen van der Schoot, Silke Rosinger, Maria Dimitriou, Wolfgang Koenig, Michael Boehnke, François Cambien, Per Lundmark, Dmitry Shungin, Wolfgang Kratzer, Pierre Zalloua, Reijo Laaksonen, Jean Ferrières, Villi Gudnason, Thorsten Kessler, Daniel J. Rader, Niclas Eriksson, Dominique Arveiler, Natalie R. van Zuydam, Kari Kuulasmaa, N. William Rayner, Sarah E. Hunt, Gudmar Thorleifsson, Jeanette Erdmann, Samuli Ripatti, Tsun-Po Yang, George A. Wells, Terho Lehtimäki, Kjell Nikus, Pierre Fontanillas, Jorg Hager, Martin Farrall, Jemma C. Hopewell, Frank Kee, Juha Sinisalo, Christopher J. O'Donnell, Asif Rasheed, Mika Kähönen, Genovefa Kolovou, Seraya Maouche, Suzanne Rafelt, Cordelia Langford, Winfried März, Leo-Pekka Lyytikäinen, Christina Willenborg, Weihua Zhang, Kati Kristiansson, Hyo-Soo Kim, Weang K. Ho, Jeong E. Park, Mohan U. Sivananthan, Moritz P. Rumpf, Markku Laakso, Klaus Stark, Philippe Amouyel, Paul W. Franks, Andres Metspalu, Anders Franco-Cereceda, Manjinder S. Sandhu, Nour Eddine El Mokhtari, Nicholas J. Wareham, Robert Roberts, Veikko Salomaa, Thomas Illig, Tomi Pastinen, Robert Clarke, Christof Burgdorf, Leif Groop, Devin Absher, Yangsoo Jang, Mark I. McCarthy, Bernhard O. Boehm, Per Eriksson, Nilesh J. Samani, Inke R. König, Stefan Schreiber, Karin Leander, Simone Claudi-Boehm, Ci Song, Benjamin A. Goldstein, Stephen E. Epstein, Andreas Ziegler, Stanley L. Hazen, Arne Schäfer, Elin Grundberg, Sekar Kathiresan, John R. Thompson, Unnur Thorsteinsdottir, Muredach P. Reilly, Heribert Schunkert, Rory Collins, Thomas Quertermous, Jong-Young Lee, John Danesh, John C. Chambers, Marco M Ferrario, Carlos Iribarren, Claudia Langenberg, Hilma Holm, Rona J. Strawbridge, Alan S. Go, Cristen J. Willer, Ron Do, Emmi Tikkanen, Abbas Dehghan, Evelin Mihailov, Lindsay L. Waite, Patrick Diemert, Willem H. Ouwehand, Eric E. Schadt, Diana Rubin, David Altshuler, Marcus E. Kleber, Markus Perola, Alexandre F.R. Stewart, Jaspal S. Kooner, Themistocles L. Assimes, Inês Barroso, Bruna Gigante, Göran Hallmans, Marja-Liisa Lokki, Aki S. Havulinna, Anders Hamsten, Agneta Siegbahn, Lasse Folkersen, Erik Ingelsson, Martina E. Zimmermann, Colin N. A. Palmer, Paolo Brambilla, Ann-Christine Syvänen, Alun Evans, Åsa Johansson, John F. Peden, Alex S. F. Doney, Hugh Watkins, Johanna Kuusisto, Anders Lundmark, David G. Cox, Hyun Min Kang, Lars Lind, Krista Fischer, Markku S. Nieminen, Annette Peters, Norman Klopp, Stefan Gustafsson, Lars Wallentin, Nancy L. Pedersen, David-Alexandre Trégouët, Ulf de Faire

المساهمون: Deloukas, P, Kanoni, S, Willenborg, C, Farrall, M, Assimes, T, Thompson, J, Ingelsson, E, Saleheen, D, Erdmann, J, Goldstein, B, Stirrups, K, König, I, Cazier, J, Johansson, Å, Hall, A, Lee, J, Willer, C, Chambers, J, Esko, T, Folkersen, L, Goel, A, Grundberg, E, Havulinna, A, Ho, W, Hopewell, J, Eriksson, N, Kleber, M, Kristiansson, K, Lundmark, P, Lyytikäinen, L, Rafelt, S, Shungin, D, Strawbridge, R, Thorleifsson, G, Tikkanen, E, Van Zuydam, N, Voight, B, Waite, L, Zhang, W, Ziegler, A, Absher, D, Altshuler, D, Balmforth, A, Barroso, I, Braund, P, Burgdorf, C, Claudi Boehm, S, Cox, D, Dimitriou, M, Do, R, Doney, A, El Mokhtari, N, Eriksson, P, Fischer, K, Fontanillas, P, Franco Cereceda, A, Gigante, B, Groop, L, Gustafsson, S, Hager, J, Hallmans, G, Han, B, Hunt, S, Kang, H, Illig, T, Kessler, T, Knowles, J, Kolovou, J, Kuusisto, J, Langenberg, C, Langford, C, Leander, K, Lokki, M, Lundmark, A, Mccarthy, M, Meisinger, C, Melander, O, Mihailov, E, Maouche, S, Morris, A, Müller Nurasyid, M, Nikus, K, Peden, J, Rayner, N, Rasheed, A, Rosinger, S, Rubin, D, Rumpf, M, Schäfer, A, Sivananthan, M, Song, C, Stewart, A, Tan, S, Thorgeirsson, G, van der Schoot, C, Wagner, P, Wells, G, Wild, P, Yang, T, Amouyel, P, Arveiler, D, Basart, H, Boehnke, M, Boerwinkle, E, Brambilla, P, Cambien, F, Cupples, A, de Faire, U, Dehghan, A, Diemert, P, Epstein, S, Evans, A, Ferrario, M, Ferrières, J, Gauguier, D, Go, A, Goodall, A, Gudnason, V, Hazen, S, Holm, H, Iribarren, C, Jang, Y, Kähönen, M, Kee, F, Kim, H, Klopp, N, Koenig, W, Kratzer, W, Kuulasmaa, K, Laakso, M, Laaksonen, R, Lind, L, Ouwehand, W, Parish, S, Park, J, Pedersen, N, Peters, A, Quertermous, T, Rader, D, Salomaa, V, Schadt, E, Shah, S, Sinisalo, J, Stark, K, Stefansson, K, Trégouët, D, Virtamo, J, Wallentin, L, Wareham, N, Zimmermann, M, Nieminen, M, Hengstenberg, C, Sandhu, M, Pastinen, T, Syvänen, A, Hovingh, G, Dedoussis, G, Franks, P, Lehtimäki, T, Metspalu, A, Zalloua, P, Siegbahn, A, Schreiber, S, Ripatti, S, Blankenberg, S, Perola, M, Clarke, R, Boehm, B, O’Donnell, C, Reilly, M, März, W, Collins, R, Kathiresan, S, Hamsten, A, Kooner, J, Thorsteinsdottir, U, Danesh, J, Palmer, C, Roberts, R, Watkins, H, Schunkert, H, Samani, N, Landsteiner Laboratory, Clinical Haematology, Other departments, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine

المصدر: Nature Genetics
Nature Genetics; Vol 45
Nature genetics, 45(1), 25-33. Nature Publishing Group
Deloukas, P, Kanoni, S, Willenborg, C, Farrall, M, Assimes, T L, Thompson, J R, Ingelsson, E, Saleheen, D, Erdmann, J, Goldstein, B A, Stirrups, K, König, I R, Cazier, J B, Johansson, Å, Hall, A S, Lee, J Y, Willer, C J, Chambers, J C, Esko, T, Folkersen, L, Goel, A, Grundberg, E, Havulinna, A S, Ho, W K, Hopewell, J C, Eriksson, N, Kleber, M E, Kristiansson, K, Lundmark, P, Lyytikäinen, L P, Rafelt, S, Shungin, D, Strawbridge, R J, Thorleifsson, G, Tikkanen, E, Van Zuydam, N, Voight, B F, Waite, L L, Zhang, W, Ziegler, A, Absher, D, Altshuler, D, Balmforth, A J, Barroso, I, Braund, P S, Burgdorf, C, Claudi-Boehm, S, Cox, D, Dimitriou, M, Do, R, Doney, A S F, El Mokhtari, N, Eriksson, P, Fischer, K, Fontanillas, P, Franco-Cereceda, A, Gigante, B, Groop, L, Gustafsson, S, Hager, J, Hallmans, G, Han, B G, Hunt, S E, Kang, H M, Illig, T, Kessler, T, Knowles, J W, Kolovou, G, Kuusisto, J, Langenberg, C, Langford, C, Leander, K, Lokki, M L, Lundmark, A, McCarthy, M I, Meisinger, C, Melander, O, Mihailov, E, Maouche, S, Morris, A D, Müller-Nurasyid, M, Nikus, K, Peden, J F, Rayner, N W, Rasheed, A, Rosinger, S, Rubin, D, Rumpf, M P, Schäfer, A, Sivananthan, M, Song, C, Stewart, A F R, Tan, S T, Thorgeirsson, G, Van Der Schoot, C E, Wagner, P J, Wells, G A, Wild, P S, Yang, T P, Amouyel, P, Arveiler, D, Basart, H, Boehnke, M, Boerwinkle, E, Brambilla, P, Cambien, F, Cupples, A L, De Faire, U, Dehghan, A, Diemert, P, Epstein, S E, Evans, A, Ferrario, M M, Ferrières, J, Gauguier, D, Go, A S, Goodall, A H, Gudnason, V, Hazen, S L, Holm, H, Iribarren, C, Jang, Y, Kähönen, M, Kee, F, Kim, H S, Klopp, N, Koenig, W, Kratzer, W, Kuulasmaa, K, Laakso, M, Laaksonen, R, Lee, J Y, Lind, L, Ouwehand, W H, Parish, S, Park, J E, Pedersen, N L, Peters, A, Quertermous, T, Rader, D J, Salomaa, V, Schadt, E, Shah, S H, Sinisalo, J, Stark, K, Stefansson, K, Trégouët, D A, Virtamo, J, Wallentin, L, Wareham, N, Zimmermann, M E, Nieminen, M S, Hengstenberg, C, Sandhu, M S, Pastinen, T, Syvänen, A C, Hovingh, G K, Dedoussis, G, Franks, P W, Lehtimäki, T, Metspalu, A, Zalloua, P A, Siegbahn, A, Schreiber, S, Ripatti, S, Blankenberg, S S, Perola, M, Clarke, R, Boehm, B O, O'Donnell, C, Reilly, M P, März, W, Collins, R, Kathiresan, S, Hamsten, A, Kooner, J S, Thorsteinsdottir, U, Danesh, J, Palmer, C N A, Roberts, R, Watkins, H, Schunkert, H & Samani, N J 2013, ' Large-scale association analysis identifies new risk loci for coronary artery disease ', Nature Genetics, vol. 45, no. 1, pp. 25-33 . https://doi.org/10.1038/ng.2480Test

مصطلحات موضوعية: Adult, Asian Continental Ancestry Group, Male, Candidate gene, BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA, Population, European Continental Ancestry Group, Quantitative Trait Loci, CAD, Genome-wide association study, Single-nucleotide polymorphism, Coronary Artery Disease, 030204 cardiovascular system & hematology, Biology, Quantitative trait locus, Bioinformatics, Polymorphism, Single Nucleotide, Article, White People, coronary artery disease, risk loci, Cell Line, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Asian People, Risk Factors, medicine, Humans, genetics, Gene Regulatory Networks, Genetic Predisposition to Disease, cardiovascular diseases, Polymorphism, education, 030304 developmental biology, Genetic association, Aged, Genetics, 0303 health sciences, education.field_of_study, Adult, Aged, Asian Continental Ancestry Group, Cell Line, Coronary Artery Disease, genetics, European Continental Ancestry Group, genetics, Female, Gene Regulatory Networks, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Risk Factors, Single Nucleotide, Middle Aged, medicine.disease, 3. Good health, Female, Genome-Wide Association Study

وصف الملف: STAMPA; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59c523925efe7daa10b4fa1438fdb4eTest

المؤلفون: Vilmundur Gudnason, Robert J. Weyant, Robert C. Kaplan, Jeffrey R. O'Connell, Panos Deloukas, Barbara McKnight, Alessandro De Grandi, Gert-Jan B. van Ommen, Eric Boerwinkle, Liming Liang, Douglas F. Levinson, Richard B. Hayes, Mark I. McCarthy, Andrew P. Morris, Joel N. Hirschhorn, Jaakko Kaprio, Nilesh J. Samani, Inke R. König, Frank B. Hu, Nicholas J. Wareham, Ozren Polasek, Michael C. Turchin, Daniel F. Gudbjartsson, Wilmar Igl, Vincent Mooser, Aki S. Havulinna, Themistocles L. Assimes, Cameron D. Palmer, Lachlan J. M. Coin, Eva Albrecht, Hana Lango Allen, Inês Barroso, Eco J. C. de Geus, H.-Erich Wichmann, Michael A. Province, Sarah H. Wild, Patricia B. Munroe, Jeanette Erdmann, Mattias Lorentzon, Michael Preuss, Nelson B. Freimer, Mika Kähönen, Tushar Bhangale, Nicole L. Glazer, Markku S. Nieminen, Andrew A. Hicks, Jonathan Tyrer, Grant W. Montgomery, Ruth J. F. Loos, Shaun Purcell, Manfred Kayser, Marjo-Riitta Järvelin, Guillaume Paré, Terho Lehtimäki, Irene Pichler, Ida Surakka, Tõnu Esko, Peter Kraft, Talin Haritunians, Juha Sinisalo, Mari Nelis, Veronique Vitart, Alan R. Sanders, Alistair S. Hall, Carlos Iribarren, Mark E. Cooper, André G. Uitterlinden, Peter Kovacs, David Schlessinger, Florian Ernst, Marja-Liisa Lokki, M. Juhani Junttila, Martin Ridderstråle, Jorma Viikari, Inga Prokopenko, Christopher J. O'Donnell, Jennie Hui, Aila Rissanen, Gonçalo R. Abecasis, Jouke-Jan Hottenga, Tomi Pastinen, Kevin B. Jacobs, Jan Smit, Kristin G. Ardlie, Niina Pellikka, Neil R. Robertson, Martina Müller, John F. Peden, Mary F. Feitosa, Thomas W. Winkler, Kari Stefansson, Jianjun Liu, Jaana Laitinen, Shen Haiqing, Martin Farrall, Nilanjan Chatterjee, Eleanor Wheeler, Tamara B. Harris, Åsa Johansson, Anders Hamsten, Elizabeth K. Speliotes, Larry D. Atwood, Valgerdur Steinthorsdottir, Elin Grundberg, Nicole Soranzo, Anna-Liisa Hartikainen, Devin Absher, Cecilia M. Lindgren, Rany M. Salem, Lorena Citterio, Karol Estrada, Sven Bergmann, Tony Kwan, Thomas Meitinger, Alan F. Wright, Richard N. Bergman, Sailaja Vedantam, Kirsi H. Pietiläinen, Lina Zgaga, Anne U. Jackson, Stefan Schreiber, Ju-Hyun Park, Nicola Glorioso, Jianxin Shi, Najaf Amin, Dale R. Nyholt, Lenore J. Launer, Heribert Schunkert, Thomas Quertermous, Mari Liis Tammesoo, Dorret I. Boomsma, Harry Campbell, Albert V. Smith, Andrew R. Wood, Caroline S. Fox, Paavo Zitting, Gabrielle Boucher, Alex N. Parker, Jennifer G. Sambrook, Joyce B. J. van Meurs, Heather M. Stringham, Marjolein J. Peters, Sekar Kathiresan, Elisabeth Widen, Caroline Hayward, Tim D. Spector, Dawn M. Waterworth, Carlo Rivolta, Antti Jula, Albert Hofman, Hugh Watkins, Wendy L. McArdle, Roberto Elosua, Markku Koiranen, Paul M. Ridker, Iris M. Heid, Lee M. Kaplan, Brenda W.J.H. Penninx, Peter M. Visscher, Claes Ohlsson, Per Hall, Benjamin F. Voight, Ben A. Oostra, Anna F. Dominiczak, Martin den Heijer, Andrea Maschio, Quince Gibson, Peter P. Pramstaller, Nigel W. Rayner, Carsten Oliver Schmidt, Toby Johnson, Henrik Grönberg, M. Carola Zillikens, Alan R. Shuldiner, Cornelia M. van Duijn, Samuli Ripatti, Erik Ingelsson, John R. Thompson, Stephen J. Chanock, Johannes Kettunen, David J. Hunter, Lyle J. Palmer, Ulf Gyllensten, Jianfeng Xu, Astrid Petersmann, Johan G. Eriksson, Guillaume Lettre, Teresa Ferreira, Fredrik Wiklund, Andreas Ziegler, Andres Metspalu, Jerome I. Rotter, Suzanne Rafelt, Julius S. Ngwa, Francis S. Collins, Michael N. Weedon, Thomas Illig, Wolfgang Hoffman, Nancy L. Heard-Costa, Anke Tönjes, Daniel I. Chasman, Alice M. Arnold, Olli T. Raitakari, Anna L. Dixon, Lu Qi, Michael E. Goddard, Anneli Pouta, Mark J. Caulfield, Liesbeth Vandenput, Christian Gieger, L. Adrienne Cupples, Veikko Salomaa, Elizabeth L. Altmaier, Nicholas G. Martin, Thomas D. Kocher, Jubao Duan, David S. Siscovick, Heikki V. Huikuri, Willem H. Ouwehand, Kari E. North, Christian Hengstenberg, Jacques S. Beckmann, Constance Chen, John Perry, Ana Marušić, Olle Melander, John D. Rioux, Erika Salvi, Andrew T. Hattersley, Paul Elliott, Leif Groop, Cristen J. Willer, Manuela Uda, Gudmar Thorleifsson, Eric E. Schadt, Charles C. White, Pablo V. Gejman, Serena Sanna, Ulla Sovio, Robert W. Lawrence, Unnur Thorsteinsdottir, Ayellet V. Segrè, Daniele Cusi, G. Bragi Walters, Ken Sin Lo, Ivana Kolcic, Igor Rudan, Sonja I. Berndt, Keri L. Monda, Soumya Raychaudhuri, Jian'an Luan, Joshua C. Randall, Anthony J. Balmforth, Yurii S. Aulchenko, Peter Almgren, Karen L. Mohlke, Timothy M. Frayling, Shamika Ketkar, Thomas H. Mosley, Markus Perola, Henry Völzke, Laura Zagato, Leena Peltonen, Seppo Koskinen, Massimo Mangino, Ke Hao, Tsegaselassie Workalemahu, Lambertus A. Kiemeney, Helene Alavere, Jaakko Tuomilehto, Reedik Mägi, James F. Wilson, Ingrid B. Borecki, Zoltán Kutalik, Michael Stumvoll, Dominique J. Verlaan, Arthur W. Musk, Eero Kajantie, Jian Yang, Joshua W. Knowles, Tuomas O. Kilpeläinen, Michael Boehnke, G. Mark Lathrop, John Beilby, Fernando Rivadeneira, Gudny Eiriksdottir, Gonneke Willemsen, Andrew C. Heath, Antonella Mulas, Katja K.H. Aben, David P. Strachan, Thor Aspelund, Jing Hua Zhao

المساهمون: Psychiatry, NCA - Anxiety & Depression, EMGO - Mental health, Internal Medicine, Epidemiology, Intensive Care, Clinical Genetics, Genetic Identification, Medical Research Council (MRC), Biological Psychology, Neuroscience Campus Amsterdam - Anxiety & Depression, EMGO+ - Mental Health, Genetics of Complex Traits, University of Exeter, Department of Epidemiology, Erasmus Medical Centre, Netherlands Genomics Initiative (NGI), Netherlands Genomics Initiative, Department of Medicine, Montreal, National Cancer Institute [Bethesda] (NCI-NIH), National Institutes of Health [Bethesda] (NIH), Department of Biostatistics, University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, deCODE Genetics, deCODE genetics [Reykjavik], Divisions of Genetics and Endocrinology and Program in Genomics, Boston Children's Hospital, Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston]-Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Institut de Génomique d'Evry (IG), Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, the Genetic Investigation of ANthropocentric Traits (GIANT) Consortium, Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

المصدر: Nature
Nature; Vol 467
Nature, 467, 7317, pp. 832-8
Nature, 467, 832-8
Nature, 467(7317), 832-838. Nature Publishing Group
Lango Allen, H, Estrada, K, Lettre, G, Berndt, S I, Weedon, M N, Rivadeneira, F, Hottenga, J J, de Geus, E J C, Willemsen, G, van Ommen, G J B, Martin, N G, Montgomery, GW, Boomsma, D I, Penninx, B W J H, van Duijn, C M, Peltonen, L, Visscher, P M, Uitterlinden, A G, Abecasis, G R, Stefansson, H, Frayling, T M & Hirschhorn, J N 2010, ' Hundreds of variants clustered in genomic loci and biological pathways affect human height ', Nature, vol. 467, no. 7317, pp. 832-838 . https://doi.org/10.1038/nature09410Test
Nature, 467(7317), 832-838
Nature, Nature Publishing Group, 2010, 467 (7317), pp.832-838. ⟨10.1038/nature09410⟩
Nature, 2010, 467 (7317), pp.832-838. ⟨10.1038/nature09410⟩

مصطلحات موضوعية: Netherlands Twin Register (NTR), Multifactorial Inheritance, [SDV]Life Sciences [q-bio], Genome-wide association study, Aetiology, screening and detection [ONCOL 5], 0302 clinical medicine, POPULATION, SNPS, Genetics, 0303 health sciences, Multidisciplinary, HERITABILITY, COMMON VARIANTS, Phenotype, DISEASES, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Science & Technology - Other Topics, GROWTH, Allelic heterogeneity, Chromosomes, Human, Pair 3, Metabolic Networks and Pathways, TRAITS, Common disease-common variant, General Science & Technology, Locus (genetics), Biology, Polymorphism, Single Nucleotide, Article, Molecular epidemiology [NCEBP 1], 03 medical and health sciences, SDG 3 - Good Health and Well-being, ADULT, STRATIFICATION, MD Multidisciplinary, Humans, Genetic Predisposition to Disease, Genetic variability, 030304 developmental biology, Science & Technology, MULTIDISCIPLINARY SCIENCES, Genome, Human, Hormonal regulation [IGMD 6], Body Height, Genetic architecture, wide association analysis common variants heritability population adult stratification diseases traits growth snps, WIDE ASSOCIATION ANALYSIS, Genetic Loci, Evaluation of complex medical interventions [NCEBP 2], Polygene, Expression quantitative trait loci, 030217 neurology & neurosurgery, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d493384b4f86f521131ee5b11d9b22cTest
https://doi.org/10.1038/nature09410Test

المؤلفون: Suzanne Rafelt, Dirk J. van Veldhuisen, Rudolf A. de Boer, Wiek H. van Gilst, Tim D. Spector, Alan J. Beveridge, Guangju Zhai, Gerjan Navis, Nilesh J. Samani, Hannah Blackburn, Irene Mateo Leach, Peter S. Braund, Alison H. Goodall, John R. Thompson, Massimo Mangino, Martin D. Tobin, Willem H. Ouwehand, Michael A. Kaiser, Ana M. Valdes, Alistair S. Hall, Veryan Codd, Pim van der Harst, Paul Burton, Christopher P. Nelson, Nicole Soranzo, Jasbir S. Moore

المساهمون: Cardiovascular Centre (CVC), Groningen Kidney Center (GKC)

المصدر: Nature Genetics, 42(3), 197-199. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics

مصطلحات موضوعية: Genetics, GENERAL-POPULATION, 0303 health sciences, Telomerase, LEUCINE-RICH REPEAT, Genome-wide association study, Locus (genetics), HUMANS, Biology, Quantitative trait locus, Telomere, Minor allele frequency, 03 medical and health sciences, Telomerase RNA component, 0302 clinical medicine, 030220 oncology & carcinogenesis, LOCUS, GENOME-WIDE ASSOCIATION, Allele frequency, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b751c4c6f6fd15475cc4e4c558ada34bTest
https://doi.org/10.1038/ng.532Test

المؤلفون: Bernhard M. Kaess, Maciej Tomaszewski, Peter S. Braund, Klaus Stark, Suzanne Rafelt, Marcus Fischer, Robert Hardwick, Christopher P. Nelson, Radoslaw Debiec, Fritz Huber, Werner Kremer, Hans Robert Kalbitzer, Lynda M. Rose, Daniel I. Chasman, Jemma Hopewell, Robert Clarke, Paul R. Burton, Martin D. Tobin, Christian Hengstenberg, Nilesh J. Samani

مصطلحات موضوعية: Uncategorized, Cardiovascular Diseases, Cholesterol, HDL, Family, Female, Genome-Wide Association Study, Genotype, Great Britain, Humans, Lipoproteins, Magnetic Resonance Spectroscopy, Male, Phenotype

العلاقة: 2381/27987; https://figshare.com/articles/journal_contribution/Large-scale_candidate_gene_analysis_of_HDL_particle_features_/10173305Test

الإتاحة: https://figshare.com/articles/journal_contribution/Large-scale_candidate_gene_analysis_of_HDL_particle_features_/10173305Test

المؤلفون: Patricia B. Munroe, Muredach P. Reilly, Suzanne Rafelt, Caroline S. Fox, Diederick E. Grobbee, Jana V. van Vliet-Ostaptchouk, George Davey-Smith, Ingo Ruczinski, Haiqing Shen, Clara C. Elbers, Pieter A. Doevendans, Michael Boehnke, Niek Verweij, John Danesh, Archana Tare, Erin N. Smith, William C. Knowler, Tom R. Gaunt, Jessica van Setten, Meena Kumari, Claire E. Hastie, Jeanne M. McCaffery, Joseph T. Glessner, Sonia Shah, Mingyao Li, Aroon D. Hingorani, Marten H. Hofker, Annemieke W M Spijkerman, Richa Saxena, John Barnard, Rhonda M. Cooper-DeHoff, Matthijs F.L. Meijs, Matthew B. Lanktree, Garret A. FitzGerald, Mark I. McCarthy, Maximilian T. Lobmeyer, Diane Gilbert-Diamond, Paul Burton, Peter S. Sever, Neil R Poulter, Bernhard O. Böhm, Inga Peter, Philippa J. Talmud, David A. Morrow, Mary Pettinger, Olaf H. Klungel, Jane F. Ferguson, Braxton D. Mitchell, Martin Farrall, Mark C.H. De Groot, Thomas S. Price, Christa Meisinger, Sanjey R. Patel, Li Zhang, Nilesh J. Samani, Cliona Molony, Günther Silbernagel, Brendan J. Keating, Ian N. M. Day, Jutta Palmen, Marc S. Sabatine, Daniel J. Rader, M. Hadi Zafarmand, James B. Meigs, Taimour Y. Langaee, Kandice Kottke-Marchant, Wolfgang Koenig, Mika Kivimäki, Stephen S. Rich, Sean P. Curtis, Barbara Thorand, Lisa A. Gilhuijs-Pederson, Struan F.A. Grant, Toby Johnson, Thomas Illig, Mieke D. Trip, Erik P A Van Iperen, Alan R. Shuldiner, Benjamin F. Voight, Alice Stanton, Cecilia E. Kim, Yiran Guo, Robert Clarke, Gail P. Jarvik, Mark J. Caulfield, James G. Wilson, Stephen Newhouse, Michael W. Steffes, Winfried März, Jessica L. Mega, Clement E. Furlong, Robert A. Hegele, Eric E. Schadt, Sandosh Padmanabhan, Tushar Bhangale, Jane E. Ranchalis, David Altshuler, Christopher P. Nelson, Anthonius de Boer, Yan Gong, W. H. Linda Kao, S. J. Bielinski, Daphne L. van der A, Jeffery R. O'Connell, Fotios Drenos, Florianne Bauer, James S. Pankow, Berta Almoguera Castillo, Carl J. Pepine, Roy L. Silverstein, Yun Li, Olle Melander, Errol D. Crook, Quince Gibson, Joseph M. Zmuda, Deepak L. Bhatt, Yvonne T. van der Schouw, Jens Baumert, Denis C. Shields, Peter S. Braund, Christian Gieger, Solomon K. Musani, David S. Siscovick, Ashok Balasubramanyam, Thomas P. Cappola, Hakon Hakonarson, Juan P. Casas, Folkert W. Asselbergs, Marcus E. Kleber, Gerald W. Dorn, Jerome I. Rotter, Debbie A Lawlor, Danish Saleheen, Cisca Wijmenga, Anuj Goel, N. Charlotte Onland-Moret, Marcel Bruinenberg, Taylor Young, Ramakrishnan Rajagopalan, Donald W. Bowden, Asif Rasheed, Alexander P. Reiner, Anders Hamsten, Paul I.W. de Bakker, Anke-Hilse Maitland-van der Zee, Anna F. Dominiczak, Bruce H. R. Wolffenbuttel, Julie A. Johnson, Gordon S. Huggins, Hareesh R. Chandrupatla, Steve E. Humphries, Hugh Watkins, Gurunathan Murugesan, Pim van der Harst, Elisabeth A. Rosenthal

المساهمون: Other departments, Pulmonology, ACS - Amsterdam Cardiovascular Sciences, Cardiology, APH - Amsterdam Public Health, Epidemiology and Data Science, Graduate School, Faculteit Medische Wetenschappen/UMCG, Life Course Epidemiology (LCE), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Center for Liver, Digestive and Metabolic Diseases (CLDM), Cardiovascular Centre (CVC), Lifestyle Medicine (LM), Vascular Ageing Programme (VAP)

المصدر: American journal of human genetics, 90(3), 410-425. Cell Press
American Journal of Human Genetics, 90(3), 410-425. CELL PRESS
The American Journal of Human Genetics; Vol 90
The American Journal of Human Genetics

مصطلحات موضوعية: Adult, Male, Candidate gene, SNP ARRAY, Adolescent, Genotype, SUSCEPTIBILITY LOCI, 030209 endocrinology & metabolism, Genome-wide association study, Single-nucleotide polymorphism, Locus (genetics), BLOOD-PRESSURE, Biology, Polymorphism, Single Nucleotide, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Ethnicity, Genetics, Humans, EUROPEAN AMERICANS, Genetic Predisposition to Disease, RESOURCE CARE, Genetics(clinical), GENOME-WIDE ASSOCIATION, Genetics (clinical), Aged, 030304 developmental biology, Genetic association, Aged, 80 and over, AFRICAN-AMERICANS, 0303 health sciences, INSULIN-RESISTANCE, COMMON VARIANTS, Middle Aged, 3. Good health, SNP genotyping, Diabetes Mellitus, Type 2, Genetic Loci, Case-Control Studies, RISK-FACTORS, Female, TCF7L2, Follow-Up Studies, Genome-Wide Association Study, SNP array

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19a12226e71db9569b3617d18ccabf7Test
https://pure.amc.nl/en/publications/largescale-genecentric-metaanalysis-across-39-studies-identifies-type-2-diabetes-lociTest(a8ec90d2-3787-4724-9da1-abf3c21cd2f8).html

المؤلفون: Christopher D Steadman, Gerry P McCann, Suzanne Rafelt, Michael Jerosch-Herold, Nilesh J. Samani, Iain B. Squire, Leong L. Ng, Benjamin Grundy

المصدر: JACC. Cardiovascular imaging. 5(2)

مصطلحات موضوعية: Aortic valve, Male, medicine.medical_specialty, Fractional flow reserve, cardiac magnetic resonance, Coronary artery disease, Coronary circulation, Oxygen Consumption, Aortic valve replacement, Internal medicine, Coronary Circulation, cardiopulmonary exercise testing, medicine, Humans, Radiology, Nuclear Medicine and imaging, Ventricular remodeling, Aged, Ejection fraction, Exercise Tolerance, Ventricular Remodeling, business.industry, aortic stenosis, Aortic Valve Stenosis, medicine.disease, Magnetic Resonance Imaging, Fractional Flow Reserve, Myocardial, myocardial perfusion reserve, medicine.anatomical_structure, Radiology Nuclear Medicine and imaging, Echocardiography, Aortic valve stenosis, Cardiology, Exercise Test, Female, Cardiology and Cardiovascular Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf5bc3febd890c12180332024d3463fTest
https://pubmed.ncbi.nlm.nih.gov/22340826Test