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1دورية أكاديمية
المؤلفون: Richard A. Noble, Natalie Bell, Helen Blair, Arti Sikka, Huw Thomas, Nicole Phillips, Sirintra Nakjang, Satomi Miwa, Rachel Crossland, Vikki Rand, Despina Televantou, Anna Long, Hector C. Keun, Chris M. Bacon, Simon Bomken, Susan E. Critchlow, Stephen R. Wedge
المصدر: Haematologica, Vol 102, Iss 7 (2017)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
العلاقة: https://haematologica.org/article/view/8131Test; https://doaj.org/toc/0390-6078Test; https://doaj.org/toc/1592-8721Test
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2دورية أكاديمية
المؤلفون: Mandy Lawson, Natalie Cureton, Susana Ros, Azadeh Cheraghchi-Bashi, Jelena Urosevic, Sophie D'Arcy, Oona Delpuech, Michelle DuPont, David I. Fisher, Eric T. Gangl, Hilary Lewis, Dawn Trueman, Neha Wali, Stuart C. Williamson, Jennifer Moss, Elodie Montaudon, Heloise Derrien, Elisabetta Marangoni, Ricardo J. Miragaia, Sladjana Gagrica, Pablo Morentin-Gutierrez, Thomas A. Moss, Gareth Maglennon, Daniel Sutton, Radoslaw Polanski, Alan Rosen, Jonathan Cairns, Pei Zhang, Mònica Sánchez-Guixé, Violeta Serra, Susan E. Critchlow, James S. Scott, Justin P.O. Lindemann, Simon T. Barry, Teresa Klinowska, Christopher J. Morrow, Larissa S Carnevalli
مصطلحات موضوعية: Cancer, Therapeutic Research and Development, Methods and Technology, Breast Cancer, Preclinical Models, Translational Research
الإتاحة: https://doi.org/10.1158/0008-5472.24710671.v1Test
https://figshare.com/articles/journal_contribution/Supplementary_Data_from_The_Next-Generation_Oral_Selective_Estrogen_Receptor_Degrader_Camizestrant_AZD9833_Suppresses_ER_sup_sup_Breast_Cancer_Growth_and_Overcomes_Endocrine_and_CDK4_6_Inhibitor_Resistance/24710671Test -
3دورية أكاديمية
المؤلفون: Aarti Kawatkar (5375711), Roger A. Clark (12300593), Lorna Hopcroft (14270985), Debora Ann Roaquin (14332941), Ronald Tomlinson (14332944), Andrea M. Zuhl (2180184), Gillian M. Lamont (1763368), Jason G. Kettle (1398433), Susan E. Critchlow (1613527), M. Paola Castaldi (2358850), Frederick W. Goldberg (1845706), Andrew X. Zhang (1371321)
مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Inorganic Chemistry, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, traditional biophysical methods, mct family members, developed three assays, demonstrated selective engagement, 10 nm ), intracellular lactic acid, dependent cell line, 50 sub, optimized compounds inhibit, optimized compounds, lactic acid, therapeutic target, therapeutic approach, taken together, readily amenable, pharmacokinetic properties, parent molecule
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4دورية أكاديمية
المؤلفون: Frederick W. Goldberg (1845706), Jason G. Kettle (1398433), Gillian M. Lamont (1763368), David Buttar (1981537), Attilla K. T. Ting (8306301), Thomas M. McGuire (1638829), Calum R. Cook (14270973), David Beattie (2299147), Pablo Morentin Gutierrez (14270976), Stefan L. Kavanagh (14270979), Jasper C. Komen (14270982), Aarti Kawatkar (5375711), Roger Clark (685993), Lorna Hopcroft (14270985), Gareth Hughes (18689), Susan E. Critchlow (1613527)
مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, resulting clinical candidate, good preclinical efficacy, close structural analogues, broad sar exploration, monocarboxylate transporter 4, mct4 may lead, selective mct4 inhibitors, clinical candidate azd0095, 15 b, mct4 inhibition may, selective inhibitor, monocarboxylate transporters, suitable properties, screen identified, produces lactate, physical properties, oral administration, often upregulated, minor modifications
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5دورية أكاديمية
المصدر: Molecular Systems Biology, Vol 18, Iss 11, Pp n/a-n/a (2022)
مصطلحات موضوعية: cancer, heterogeneity, metabolomics, mutation, Biology (General), QH301-705.5, Medicine (General), R5-920
العلاقة: https://doi.org/10.15252/msb.202211006Test; https://doaj.org/toc/1744-4292Test; https://doaj.org/article/0313cb9805bf4769a4632f9cd173f143Test
الإتاحة: https://doi.org/10.15252/msb.202211006Test
https://doaj.org/article/0313cb9805bf4769a4632f9cd173f143Test -
6دورية أكاديمية
المؤلفون: Jeffrey W. Johannes (1414039), Amber Balazs (9436515), Derek Barratt (8921054), Michal Bista (160356), Matthew D. Chuba (11486389), Sabina Cosulich (466728), Susan E. Critchlow (1613527), Sébastien L. Degorce (1436623), Paolo Di Fruscia (3748813), Scott D. Edmondson (1416967), Kevin Embrey (1637887), Stephen Fawell (5867138), Avipsa Ghosh (1329021), Sonja J. Gill (11486392), Anders Gunnarsson (1454497), Sudhir M. Hande (2047519), Tom D. Heightman (236769), Paul Hemsley (4414534), Giuditta Illuzzi (11486395), Jordan Lane (11486398), Carrie Larner (11486401), Elisabetta Leo (16336), Lina Liu (227490), Andrew Madin (2369338), Scott Martin (8770), Lisa McWilliams (3115182), Mark J. O’Connor (512930), Jonathan P. Orme (2570623), Fiona Pachl (1643695), Martin J. Packer (1716334), Xiaohui Pei (8775905), Andrew Pike (689657), Marianne Schimpl (208250), Hongyao She (11486404), Anna D. Staniszewska (11486407), Verity Talbot (6084164), Elizabeth Underwood (9210380), Jeffrey G. Varnes (2499496), Lin Xue (826042), Tieguang Yao (9761206), Ke Zhang (115386), Andrew X. Zhang (1371321), Xiaolan Zheng (1638844)
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, overlapping hematological toxicities, good secondary pharmacology, brca mutant hbcx, brca mutant background, achieved regulatory approval, 17 pdx model, parp family members, oxo ‑ 5, dihydro ‑ 1, selective parp1 inhibitor, 25 b, n <, highly selective, vivo efficacy, usually due, reduced effects, recent literature, preclinical species, physicochemical properties, parps poly, parp1 inhibition, line chemotherapies
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7
المؤلفون: Ian J. Stratford, Susan E. Critchlow, Paul D. Smith, Kaye J. Williams, Brian A. Telfer, Kathryn G. Blount, Filippos Michopoulos, Amy L. Chadwick, Becky M. Bola
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2310b6caa33dbfec3004ae7b7846fb5cTest
https://doi.org/10.1158/1535-7163.22502373.v1Test -
8
المؤلفون: Adrian L. Harris, Michael J.O. Wakelam, Eyal Gottlieb, Almut Schulze, Susan E. Critchlow, Eric O. Aboagye, Barrie Peck, Zachary T. Schug, Elizabeth A. Smethurst, Qifeng Zhang, Syed Haider, Alessandro Valli, Dylan T. Jones
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296bb68cd5c019936a1ef3f8f3f2c884Test
https://doi.org/10.1158/1535-7163.22508365Test -
9
المؤلفون: Adrian L. Harris, Michael J.O. Wakelam, Eyal Gottlieb, Almut Schulze, Susan E. Critchlow, Eric O. Aboagye, Barrie Peck, Zachary T. Schug, Elizabeth A. Smethurst, Qifeng Zhang, Syed Haider, Alessandro Valli, Dylan T. Jones
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60daf610bff0e2bf95b43c86f86c0cb4Test
https://doi.org/10.1158/1535-7163.22508368.v1Test -
10
المؤلفون: Ian J. Stratford, Susan E. Critchlow, Paul D. Smith, Kaye J. Williams, Brian A. Telfer, Kathryn G. Blount, Filippos Michopoulos, Amy L. Chadwick, Becky M. Bola
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239bf5d52582a77f81fb409e543bc529Test
https://doi.org/10.1158/1535-7163.22502370Test