المؤلفون: Lucia Esposito, Oliver Werz, Stefanie Liening, Thomas Hanke, Andreas Koeberle, Antonietta Rossi, Daniela Schuster, Fabiana Troisi, Sun-Yee Cheung, Stefanie König, Manfred Schubert-Zsilavecz, Markus Werner, Simona Pace, Vincenza Cantone, Rossella Bilancia, Roberta Rizza, Fiorentina Roviezzo, Hermann Stuppner, Jana Gerstmeier, Veronika Temml

المساهمون: Cheung, Sun-Yee, Werner, Marku, Esposito, Lucia, Troisi, Fabiana, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Gerstmeier, Jana, Koeberle, Andrea, Bilancia, Rossella, Rizza, Roberta, Rossi, Antonietta, Roviezzo, Fiorentina, Temml, Veronika, Schuster, Daniela, Stuppner, Hermann, Schubert-Zsilavecz, Manfred, Werz, Oliver, Hanke, Thoma, Pace, Simona

المصدر: European Journal of Medicinal Chemistry. 156:815-830

مصطلحات موضوعية: Male, 0301 basic medicine, Macrophage, Prostaglandin, Inflammation, Lipoxygenase Inhibitor, Proximity ligation assay, Pharmacology, Sulfonamide, Prostaglandin-E Synthase, Mice, 03 medical and health sciences, chemistry.chemical_compound, HEK293 Cell, Biosynthesis, Drug Discovery, medicine, Microsomal prostaglandin E2 synthase-1, Prostaglandin E2, Cells, Cultured, 5-Lipoxygenase, Arachidonate 5-Lipoxygenase, biology, Animal, Drug Discovery3003 Pharmaceutical Science, Specialized pro-resolving mediator, Organic Chemistry, General Medicine, Lipid signaling, Transfection, Molecular Docking Simulation, Anti-Inflammatory Agent, 030104 developmental biology, chemistry, Lipid mediator, Arachidonate 5-lipoxygenase, biology.protein, medicine.symptom, Human, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424c429e9a07ec2db7a177be38704e75Test
https://doi.org/10.1016/j.ejmech.2018.07.031Test

المؤلفون: Maike Windbergs, Marius Friedrich, Xiaomin Ni, Sun-Yee Cheung, Apirat Chaikuad, Marek Wanior, Manfred Schubert-Zsilavecz, Simone Schierle, Jan Heering, Ewgenij Proschak, Giuseppe Faudone, Viktoria Planz, Thomas Hanke, Whitney Kilu, Oliver Werz, Stefan Knapp, Daniel Merk

المساهمون: Publica

مصطلحات موضوعية: chemistry.chemical_classification, Binding Sites, HEK 293 cells, Peroxisome proliferator-activated receptor, Hep G2 Cells, Plasma protein binding, Peroxisome, Crystallography, X-Ray, Ligands, Cell biology, PPAR gamma, HEK293 Cells, chemistry, Adipogenesis, Drug Discovery, Humans, Molecular Medicine, Benzothiazoles, Binding site, Receptor, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6e187101295eb2e80dd7d29c60b7f2Test
https://publica.fraunhofer.de/handle/publica/263782Test

المؤلفون: Sun-Yee, Cheung, Markus, Werner, Lucia, Esposito, Fabiana, Troisi, Vincenza, Cantone, Stefanie, Liening, Stefanie, König, Jana, Gerstmeier, Andreas, Koeberle, Rossella, Bilancia, Roberta, Rizza, Antonietta, Rossi, Fiorentina, Roviezzo, Veronika, Temml, Daniela, Schuster, Hermann, Stuppner, Manfred, Schubert-Zsilavecz, Oliver, Werz, Thomas, Hanke, Simona, Pace

المصدر: European journal of medicinal chemistry. 156

مصطلحات موضوعية: Inflammation, Male, Sulfonamides, Arachidonate 5-Lipoxygenase, Macrophages, Anti-Inflammatory Agents, Molecular Docking Simulation, Mice, HEK293 Cells, Animals, Humans, Lipoxygenase Inhibitors, Cells, Cultured, Prostaglandin-E Synthases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::68c0d7ab43ea951b96875fc4e1a4eef7Test
https://pubmed.ncbi.nlm.nih.gov/30053720Test

المؤلفون: Markus Hartmann, Daniel Flesch, Astrid Kaiser, Pascal Heitel, Jan S. Kramer, Hartmut Lüddens, Sun-Yee Cheung, Manfred Schubert-Zsilavecz, Mario Wurglics, Jan Heering, Daniel Merk, Ewgenij Proschak, Jurema Schmidt, Matthias Gabler, Kerstin Lüddens-Dämgen, Mara Lindner, Christina Lamers

المساهمون: Publica

المصدر: Journal of medicinal chemistry. 60(16)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.drug_class, Pyridines, Peroxisome proliferator-activated receptor, Receptors, Cytoplasmic and Nuclear, ATP-binding cassette transporter, Cholesterol 7 alpha-hydroxylase, 01 natural sciences, Rats, Sprague-Dawley, 03 medical and health sciences, Structure-Activity Relationship, Drug Stability, Drug Discovery, medicine, Glucose homeostasis, Animals, Humans, PPAR alpha, Receptor, Cholesterol 7-alpha-Hydroxylase, ATP Binding Cassette Transporter, Subfamily B, Member 11, chemistry.chemical_classification, Bile acid, 010405 organic chemistry, Chemistry, HEK 293 cells, Imidazoles, Membrane Transport Proteins, Hep G2 Cells, 0104 chemical sciences, Molecular Docking Simulation, Zolpidem, 030104 developmental biology, HEK293 Cells, Biochemistry, Molecular Medicine, Farnesoid X receptor, ATP-Binding Cassette Transporters, Sterol Regulatory Element Binding Protein 1, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a37a7cec6385e5a7b8e632cd9410315Test
https://pubmed.ncbi.nlm.nih.gov/28749691Test

المؤلفون: Flesch, Daniel¹, Sun-Yee Cheung¹, Schmidt, Jurema¹, Gabler, Matthias¹, Heitel, Pascal¹, Kramer, Jan¹, Kaiser, Astrid¹, Hartmann, Markus¹, Lindner, Mara², Luddens-Damgen, Kerstin³, Heering, Jan², Lamers, Christina¹, Luddens, Hartmut³, Wurglics, Mario¹, Proschak, Ewgenij¹, Schubert-Zsilavecz, Manfred¹, Merk, Daniel¹ merk@pharmchem.uni-frankfurt.de

المصدر: Journal of Medicinal Chemistry. 8/24/2017, Vol. 60 Issue 16, p7199-7205. 7p.

مصطلحات موضوعية: *FARNESOID X receptor, *LIVER disease prevention, *BILE acids