المؤلفون: Elhemely, Mai A., Belgath, Asma A., El-Sayed, Sherihan, Burusco, Kepa K., Kadirvel, Manikandan, Tirella, Annalisa, Finegan, Katherine, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

المساهمون: Elhemely, Mai A., Belgath, Asma A., El-Sayed, Sherihan, Burusco, Kepa K., Kadirvel, Manikandan, Tirella, Annalisa, Finegan, Katherine, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

العلاقة: volume:65; issue:6; firstpage:4783; lastpage:4797; numberofpages:15; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11572/346904Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01936Test
https://hdl.handle.net/11572/346904Test

المؤلفون: Atiomo, William, Shafiee, Mohamad Nasir, Chapman, Caroline, Metzler, Veronika M., Abouzeid, Jad, Latif, Ayşe, Chadwick, Amy, Kitson, Sarah, Sivalingam, Vanitha N., Stratford, Ian J., Rutland, Catrin S., Persson, Jenny L., Ødum, Niels, Fuentes-Utrilla, Pablo, Jeyapalan, Jennie N., Heery, David M, Crosbie, Emma J., Mongan, Nigel P.

المصدر: Clinical Endocrinology BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 87(5):557-565

مصطلحات موضوعية: endometrial cancer, endometrium, NQO1, polycystic ovary syndrome, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/5dc47e69-c983-457c-a82f-cf1eb38c432bTest
http://dx.doi.org/10.1111/cen.13436Test

المؤلفون: Hussein, Buthaina, Ikhmais, Balqis, Kadirvel, Manikandan, Magwaza, Rachael N., Halbert, Gavin, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

مصطلحات موضوعية: Therapeutics. Pharmacology

وصف الملف: text

العلاقة: https://strathprints.strath.ac.uk/88494/1/Hussein-etal-EJMC-2019-Discovery-of-potent-4-aminoquinoline-hydrazone-inhibitors.pdfTest; Hussein, Buthaina and Ikhmais, Balqis and Kadirvel, Manikandan and Magwaza, Rachael N. and Halbert, Gavin and Bryce, Richard A. and Stratford, Ian J. and Freeman, Sally (2019 ) Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2). European Journal of Medicinal Chemistry , 182. 111649. ISSN 0223-5234

الإتاحة: https://doi.org/10.1016/j.ejmech.2019.111649Test
https://strathprints.strath.ac.uk/88494Test/
https://strathprints.strath.ac.uk/88494/1/Hussein-etal-EJMC-2019-Discovery-of-potent-4-aminoquinoline-hydrazone-inhibitors.pdfTest

المؤلفون: Freeman, Sally, Stratford, Ian, Kadirvel, Manikandan, Bryce, Richard

المصدر: Freeman , S , Stratford , I , Kadirvel , M & Bryce , R 2019 , ' Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2) ' , European Journal of Medicinal Chemistry . https://doi.org/10.1016/j.ejmech.2019.111649Test

مصطلحات موضوعية: NQO2 inhibitors, anticancer, 4-aminoquinoline, hydrazine, ovarian cancer, SKOV-3 cells, TOV-112D cells, CB1954

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: https://research.manchester.ac.uk/en/publications/a0e46132-b202-44b7-9ff6-e34f7851db34Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2019.111649Test
https://research.manchester.ac.uk/en/publications/a0e46132-b202-44b7-9ff6-e34f7851db34Test
https://pure.manchester.ac.uk/ws/files/128128241/BHRM_EJMC_Final_corrected.docxTest

المؤلفون: Megarity, Clare F., Abdel-Aal Bettley, Hoda, Caraher, M. Clare, Scott, Katherine A., Whitehead, Roger C., Jowitt, Thomas A., Gutierrez, Aldo, Bryce, Richard A., Nolan, Karen A., Stratford, Ian J., Timson, David J.

المصدر: Megarity , C F , Abdel-Aal Bettley , H , Caraher , M C , Scott , K A , Whitehead , R C , Jowitt , T A , Gutierrez , A , Bryce , R A , Nolan , K A , Stratford , I J & Timson , D J 2019 , ' Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1) ' , CHEMBIOCHEM , vol. 20 , no. 22 , pp. 2841-2849 . https://doi.org/10.1002/cbic.201900313Test

مصطلحات موضوعية: cancer-associated proteins, elastic network models, enzyme cooperativity, protein flexibility, quinone oxidoreductases

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الإتاحة: https://doi.org/10.1002/cbic.201900313Test
https://research.manchester.ac.uk/en/publications/b19365fc-677f-4182-bbe6-16aac8fb102bTest
https://pure.manchester.ac.uk/ws/files/112798496/ChemBioChem_SUBMIT_R1.docxTest
http://www.scopus.com/inward/record.url?scp=85068889898&partnerID=8YFLogxKTest

المؤلفون: Rios de la Rosa, Julio M., Pingrajai, Ponpawee, Pelliccia, Maria, Spadea, Alice, Lallana, Enrique, Gennari, Arianna, Stratford, Ian J., Rocchia, Walter, Tirella, Annalisa, Tirelli, Nicola

المساهمون: Engineering and Physical Sciences Research Council, University of Manchester, Biotechnology and Biological Sciences Research Council, Innovate UK, FP7 Health

المصدر: Advanced Healthcare Materials ; volume 8, issue 24 ; ISSN 2192-2640 2192-2659

الإتاحة: https://doi.org/10.1002/adhm.201901182Test

المؤلفون: Sivalingam, Vanitha N., Latif, Ayşe, Kitson, Sarah, McVey, Rhona, Finegan, Katherine G., Marshall, Kay, Lisanti, Michael P., Sotgia, Federica, Stratford, Ian J., Crosbie, Emma J.

المساهمون: DH | National Institute for Health Research

المصدر: British Journal of Cancer ; volume 122, issue 1, page 62-71 ; ISSN 0007-0920 1532-1827

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1038/s41416-019-0627-yTest
http://www.nature.com/articles/s41416-019-0627-y.pdfTest
http://www.nature.com/articles/s41416-019-0627-yTest

المؤلفون: Mehibel, Manal, Ortiz-martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.

المصدر: Mehibel , M , Ortiz-martinez , F , Voelxen , N , Boyers , A , Chadwick , A , Telfer , B A , Mueller-klieser , W , West , C M , Critchlow , S E , Williams , K J & Stratford , I J 2018 , ' Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters ' , Scientific Reports , vol. 8 , no. 1 , 16804 . https://doi.org/10.1038/s41598-018-35103-1Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1038/s41598-018-35103-1Test
https://research.manchester.ac.uk/en/publications/3ce33dc7-bdcb-4096-96eb-6a3f59388d59Test
http://www.nature.com/articles/s41598-018-35103-1Test

المؤلفون: Sharma, Ricky A., Plummer, Ruth, Stock, Julie K., Greenhalgh, Tessa A., Ataman, Ozlem, Kelly, Stephen, Clay, Robert, Adams, Richard A., Baird, Richard D., Billingham, Lucinda, Brown, Sarah R., Buckland, Sean, Bulbeck, Helen, Chalmers, Anthony J., Clack, Glen, Cranston, Aaron N., Damstrup, Lars, Ferraldeschi, Roberta, Forster, Martin D., Golec, Julian, Hagan, Russell M., Hall, Emma, Hanauske, Axel-R., Harrington, Kevin J., Haswell, Tom, Hawkins, Maria A., Illidge, Tim, Jones, Hazel, Kennedy, Andrew S., McDonald, Fiona, Melcher, Thorsten, O'Connor, James P. B., Pollard, John R., Saunders, Mark P., Sebag-Montefiore, David, Smitt, Melanie, Staffurth, John, Stratford, Ian J., Wedge, Stephen R.

وصف الملف: text

العلاقة: http://eprints.gla.ac.uk/168118/1/168118.pdfTest; Sharma, R. A. et al. (2018) Clinical development of new drug–radiotherapy combinations. Nature Reviews Clinical Oncology , 13(10), pp. 627-642. (doi:10.1038/nrclinonc.2016.79 ) (PMID:27245279)

الإتاحة: https://doi.org/10.1038/nrclinonc.2016.79Test
http://eprints.gla.ac.uk/168118Test/
http://eprints.gla.ac.uk/168118/1/168118.pdfTest

المؤلفون: Greenwood, Daniel, Stratford, Ian

المصدر: Greenwood , D & Stratford , I 2017 , ' A review of dose escalation methods in first-in-human small molecule oncology clinical trials ' , Trials , vol. 18 , pp. 233-234 . https://doi.org/10.1186/s13063-017-1902-yTest

الإتاحة: https://doi.org/10.1186/s13063-017-1902-yTest
https://research.manchester.ac.uk/en/publications/1ba4407b-22b2-4172-abba-b900f6b5ebf7Test