المؤلفون: Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K, Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J, Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S, Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D Gareth R, Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B, González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N A, Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L, Nevanlinna, Heli, Olson, Janet E, Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E, Rosseel, Toon, Ruddy, Kathryn J, Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E, Trentham-Dietz, Amy, Vachon, Celine M, Volk, Alexander E, Weber-Lassalle, Nana, Weitzel, Jeffrey N, Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B, Vega, Ana, Rossing, Maria, Del Valle, Jesús, De Nicolo, Arcangela, Hahnen, Eric, Claes, Kathleen B M, Ngeow, Joanne, Momozawa, Yukihide, James, Paul A, Couch, Fergus J, Macurek, Libor, Kleibl, Zdenek

المساهمون: Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K, Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J, Boddicker, Nichola, Brunet, Joan, Burnside, Elizabeth S, Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, Depersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D Gareth R, Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B, González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, Jame, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, Jame, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, Mcinerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N A, Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L, Nevanlinna, Heli, Olson, Janet E, Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E, Rosseel, Toon, Ruddy, Kathryn J, Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E, Trentham-Dietz, Amy, Vachon, Celine M, Volk, Alexander E, Weber-Lassalle, Nana, Weitzel, Jeffrey N, Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakouli, Yao, Song, Zampiga, Valentina, Zethoven, Magnu, Zhang, Ze Wen, Zima, Toma, Spurdle, Amanda B, Vega, Ana, Rossing, Maria

مصطلحات موضوعية: chek2, breast cancer, germline missense variants

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37449874; info:eu-repo/semantics/altIdentifier/wos/WOS:001053492300001; volume:29; issue:16; firstpage:1; lastpage:14; numberofpages:14; journal:CLINICAL CANCER RESEARCH; https://hdl.handle.net/11573/1685106Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85168222787

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-23-0212Test
https://hdl.handle.net/11573/1685106Test

المؤلفون: Kleiblova, Petra, Stolarova, Lenka, Krizova, Katerina, Lhota, Filip, Hojny, Jan, Zemankova, Petra, Havranek, Ondrej, Vocka, Michal, Cerna, Marta, Lhotova, Klara, Borecka, Marianna, Janatova, Marketa, Soukupova, Jana, Sevcik, Jan, Zimovjanova, Martina, Kotlas, Jaroslav, Panczak, Ales, Vesela, Kamila, Cervenkova, Jana, Schneiderova, Michaela, Burocziova, Monika, Burdova, Kamila, Stranecky, Viktor, Foretova, Lenka, Machackova, Eva, Tavandzis, Spiros, Kmoch, Stanislav, Macurek, Libor, Kleibl, Zdenek

المساهمون: Akademie Věd České Republiky, Grantová Agentura, Univerzita Karlova, Ministerstvo Školství, Mládeže a Tělovýchovy, Ministerstvo Zdravotnictví Ceské Republiky

المصدر: International Journal of Cancer ; volume 145, issue 7, page 1782-1797 ; ISSN 0020-7136 1097-0215

الإتاحة: https://doi.org/10.1002/ijc.32385Test

المؤلفون: Burke, Leslie J., Sevcik, Jan, Gambino, Gaetana, Tudini, Emma, Mucaki, Eliseos J., Shirley, Ben C., Whiley, Phillip, Parsons, Michael T., De Leeneer, Kim, Gutiérrez-Enríquez, Sara, Santamariña, Marta, Caputo, Sandrine M., Santana dos Santos, Elizabeth, Soukupova, Jana, Janatova, Marketa, Zemankova, Petra, Lhotova, Klara, Stolarova, Lenka, Borecka, Mariana, Moles-Fernández, Alejandro, Manoukian, Siranoush, Bonanni, Bernardo, Edwards, Stacey L., Blok, Marinus J., van Overeem Hansen, Thomas, Rossing, Maria, Diez, Orland, Vega, Ana, Claes, Kathleen B.M., Goldgar, David E., Rouleau, Etienne

المصدر: Biochemistry Publications

مصطلحات موضوعية: BRCA1, BRCA2, breast cancer, promoter, transcription, variants of unknown clinical significance (VUS), Biochemistry

وصف الملف: application/pdf

العلاقة: https://ir.lib.uwo.ca/biochempub/218Test; https://ir.lib.uwo.ca/context/biochempub/article/1224/viewcontent/humu.23652.pdfTest

الإتاحة: https://doi.org/10.1002/humu.23652Test
https://ir.lib.uwo.ca/biochempub/218Test
https://ir.lib.uwo.ca/context/biochempub/article/1224/viewcontent/humu.23652.pdfTest

المؤلفون: Soukupova, Jana, Zemankova, Petra, Lhotova, Klara, Janatova, Marketa, Borecka, Marianna, Stolarova, Lenka, Lhota, Filip, Foretova, Lenka, Machackova, Eva, Stranecky, Viktor, Tavandzis, Spiros, Kleiblova, Petra, Vocka, Michal, Hartmannova, Hana, Hodanova, Katerina, Kmoch, Stanislav, Kleibl, Zdenek

المساهمون: Bandapalli, Obul Reddy, Ministerstvo Zdravotnictví Ceské Republiky, Grantová Agentura, Univerzita Karlova, Ministerstvo Školství, Mládeže a Tělovýchovy

المصدر: PLOS ONE ; volume 13, issue 4, page e0195761 ; ISSN 1932-6203

الإتاحة: https://doi.org/10.1371/journal.pone.0195761Test

المؤلفون: Stolařová, Lenka

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.11956/172179Test; 245967

الإتاحة: https://doi.org/20.500.11956/172179Test
https://hdl.handle.net/20.500.11956/172179Test

المؤلفون: Stolarova, Lenka, Kleiblova, Petra, Janatova, Marketa, Soukupova, Jana, Zemankova, Petra, Macurek, Libor, Kleibl, Zdenek

المصدر: Cells, Vol 9, Iss 2675, p 2675 (2020)
Cells

مصطلحات موضوعية: checkpoint kinase 2, CHK2, renal cancer, WIP1, colorectal cancer, Review, prostate cancer, breast cancer, hereditary cancer, germline mutation, lcsh:Biology (General), KAP1, thyroid cancer, skin and connective tissue diseases, lcsh:QH301-705.5, CHEK2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::81f6dbcc15e3835285d71799ba5e062eTest
https://www.mdpi.com/2073-4409/9/12/2675Test

المؤلفون: Stolarova, Lenka, Jelinkova, Sandra, Storchova, Radka, Machackova, Eva, Zemankova, Petra, Vocka, Michal, Kodet, Ondrej, Kral, Jan, Cerna, Marta, Volkova, Zuzana, Janatova, Marketa, Soukupova, Jana, Stranecky, Viktor, Dundr, Pavel, Foretova, Lenka, Macurek, Libor, Kleiblova, Petra, Kleibl, Zdenek

المصدر: Biomedicines, Vol 8, Iss 404, p 404 (2020)
Biomedicines

مصطلحات موضوعية: panel sequencing, lcsh:Biology (General), NGS, melanoma, germline mutations, neoplasms, familial melanoma, hereditary cancer predisposition, lcsh:QH301-705.5, Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e447fdd3c07aa9b7e594b09dacd7367Test
https://www.mdpi.com/2227-9059/8/10/404Test

المؤلفون: Stolařová, Lenka

المساهمون: Kleibl, Zdeněk, Eckschlager, Tomáš, Souček, Pavel, Macůrek, Libor

مصطلحات موضوعية: NGS, CZECANCA, panel sequencing, cancer predisposition, functional analysis, CHEK2, CHK2 kinase, panelové sekvenování, nádorová predispozice, funkční analýza, kináza CHK2

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.11956/147770Test; 172168

الإتاحة: https://doi.org/20.500.11956/147770Test
https://hdl.handle.net/20.500.11956/147770Test

المؤلفون: Stolařová, Lenka

المساهمون: Kleibl, Zdeněk, Živný, Jan

مصطلحات موضوعية: kináza CHEK2, missene mutace, klonování, cílená mutageneza, exprese in vitro, kinázová aktivita, CHEK2 kinase, missense mutations, clonning, side-directed mutagenesis, in vitro expression, kinase activity

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.11956/84078Test; 143851; 002029022

الإتاحة: https://doi.org/20.500.11956/84078Test
https://hdl.handle.net/20.500.11956/84078Test

المؤلفون: Stolařová, Lenka

المساهمون: Kleibl, Zdeněk, Brábek, Jan

مصطلحات موضوعية: CHEK2, Chk2, reparace DNA, buněčný cyklus, apoptóza, ATM, p53, Cdc25A, Cdc25C, BRCA2, PLK3, nádorová predispozice, karcinom prsu, DNA repair, cell cycle, apoptosis, cancer predisposition, breast cancer

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.11956/57120Test; 131265; 001627762

الإتاحة: https://doi.org/20.500.11956/57120Test
https://hdl.handle.net/20.500.11956/57120Test