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1دورية أكاديمية
المؤلفون: Céline Martin, Patricia Passilly-Degrace, Michaël Chevrot, Déborah Ancel, Steven M. Sparks, Daniel J. Drucker, Philippe Besnard
المصدر: Journal of Lipid Research, Vol 53, Iss 11, Pp 2256-2265 (2012)
مصطلحات موضوعية: long-chain fatty acid, eating behavior, obesity risk, health, Biochemistry, QD415-436
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S002222752041243XTest; https://doaj.org/toc/0022-2275Test
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2
المؤلفون: Lindsey T. Harston, David J. Cowan, Shane Roller, Caroline J. Diaz, Thomas J. Rimele, Channa K Jayawickreme, Paul Kenneth Spearing, Grace Chen, Claudia Generaux, Steven M. Sparks
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4673-4677
مصطلحات موضوعية: 0301 basic medicine, Agonist, Cell Membrane Permeability, Pyrrolidines, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Nutrient sensing, Biochemistry, Madin Darby Canine Kidney Cells, Structure-Activity Relationship, 03 medical and health sciences, Dogs, 0302 clinical medicine, Diabetes mellitus, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Chemistry, Organic Chemistry, medicine.disease, Amino acid, Gastrointestinal Tract, HEK293 Cells, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Calcium, Calcium-sensing receptor, Receptors, Calcium-Sensing
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5cff97923626224d4239e9737b3327Test
https://doi.org/10.1016/j.bmcl.2017.09.008Test -
3
المؤلفون: Erin Swiger, Thomas J. Rimele, Vincent Rash, David Moncol, Donald L. Hertzog, Caroline J. Diaz, Jon L. Collins, Christopher Nystrom, Pierette Banker, David J. Cowan, Channa K Jayawickreme, Josephine Yuen, Sean Ross, Shane Roller, Xi Liang, Steven M. Sparks, Christopher Joseph Aquino, Dock Steven Thomas, Grace Chen
المصدر: Bioorganicmedicinal chemistry letters. 27(5)
مصطلحات موضوعية: 0301 basic medicine, Agonist, Blood Glucose, Male, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Nutrient sensing, Phenylpropanoic acid, Biochemistry, Receptors, G-Protein-Coupled, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Free fatty acid receptor 1, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Phenylpropionates, Chemistry, Organic Chemistry, GPR120, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Diabetes Mellitus, Type 2, Molecular Medicine, Metabolic syndrome, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0000e4878dd27a08bc977f6b9de96aTest
https://pubmed.ncbi.nlm.nih.gov/28148462Test -
4
المؤلفون: Lindsey T. Harston, Janet H. Parham, Huiqiang Zhou, Channa K Jayawickreme, Patrick Condreay, Steven M. Sparks, Thomas J. Rimele, Claudia Generaux, David Moncol
المصدر: Bioorganicmedicinal chemistry letters. 26(8)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Pharmaceutical Science, Phenylenediamines, Biochemistry, Madin Darby Canine Kidney Cells, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Dogs, Drug Discovery, Tissue specific, Structure–activity relationship, Animals, Humans, Scavenger receptor, Molecular Biology, Sulfonamides, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Madin Darby canine kidney cell, Scavenger Receptors, Class B, Rats, 030104 developmental biology, Organ Specificity, 030220 oncology & carcinogenesis, Molecular Medicine, Identification (biology)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f311acef4d0bd59a6c64d690a4628003Test
https://pubmed.ncbi.nlm.nih.gov/26988301Test -
5
المؤلفون: David M. Bickett, Francis X. Tavares, Pamela L. Golden, Lauren R. Sheckler, Stephen A. Thomson, Dulce Garrido, Andrew J. Peat, Pierette Banker, James E. Weiel, Steven M. Sparks, Scott Howard Dickerson, Daphne C. Clancy
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:981-985
مصطلحات موضوعية: Threonine, Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Glycine, Pharmaceutical Science, Ether, Crystallography, X-Ray, Imides, Biochemistry, Serine, Inhibitory Concentration 50, chemistry.chemical_compound, Glycogen phosphorylase, Drug Discovery, Glycosyltransferase, Animals, Humans, ortho-Aminobenzoates, Phosphorylase kinase, Glycogen synthase, Molecular Biology, Cytochrome P-450 CYP2C9, biology, Chemistry, Glycogen Phosphorylase, Organic Chemistry, Rats, Diabetes Mellitus, Type 2, Liver, Models, Chemical, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Aryl Hydrocarbon Hydroxylases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5159b246433fa9027e6bcec99dce7745Test
https://doi.org/10.1016/j.bmcl.2008.11.084Test -
6
المؤلفون: Pierette Banker, Daphne C. Clancy, Francis X. Tavares, Pamela L. Golden, Liping Wang, James E. Weiel, Steven M. Sparks, Stephen A. Thomson, Lauren R. Sheckler, Dulce Garrido, Scott Howard Dickerson, Andrew J. Peat, David M. Bickett, H. Luke Carter, Kate A. Dwornik, Robert T. Nolte
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:976-980
مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Carboxylic acid, Clinical Biochemistry, Carboxylic Acids, Glycine, Molecular Conformation, Pharmaceutical Science, Crystallography, X-Ray, Imides, Biochemistry, Inhibitory Concentration 50, chemistry.chemical_compound, Glycogen phosphorylase, Dogs, Drug Discovery, Animals, Humans, ortho-Aminobenzoates, Glycogen synthase, Phosphorylase kinase, Molecular Biology, Cytochrome P-450 CYP2C9, chemistry.chemical_classification, Glycogen, biology, Glycogen Phosphorylase, Organic Chemistry, Rats, Amino acid, Enzyme, Diabetes Mellitus, Type 2, Liver, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Aryl Hydrocarbon Hydroxylases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccab5b862050e9a20580b438b03c30f9Test
https://doi.org/10.1016/j.bmcl.2008.11.085Test -
7Tandem intramolecular benzyne–furan cycloadditions. Total synthesis of vineomycinone B2 methyl ester
المؤلفون: Chi-Li Chen, Steven M. Sparks, Stephen F. Martin
المصدر: Tetrahedron. 63:8619-8635
مصطلحات موضوعية: Tandem, Stereochemistry, Organic Chemistry, Convergent synthesis, Regioselectivity, Total synthesis, Ring (chemistry), Biochemistry, Aryne, Article, chemistry.chemical_compound, chemistry, Intramolecular force, Furan, Drug Discovery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e68756f5e28af337ed3bd5b228e45f8Test
https://doi.org/10.1016/j.tet.2007.04.031Test -
8
المؤلفون: Steven M Sparks, Brad R. Henke
المصدر: Mini-Reviews in Medicinal Chemistry. 6:845-857
مصطلحات موضوعية: Glycogenolysis, Type 2 diabetes, Carbohydrate metabolism, Pharmacology, Glycogen phosphorylase, chemistry.chemical_compound, Diabetes mellitus, Drug Discovery, medicine, Humans, Hypoglycemic Agents, Enzyme Inhibitors, chemistry.chemical_classification, Glycogen, Chemistry, Glycogen Phosphorylase, Biological activity, General Medicine, medicine.disease, Glucose, Enzyme, Diabetes Mellitus, Type 2, Liver, Hyperglycemia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f72b451924e47f045d7af81998aca71Test
https://doi.org/10.2174/138955706777934991Test -
9
المؤلفون: Kenneth J. Shea, Steven M. Sparks, Chun P. Chow, Liang Zhu
المصدر: The Journal of Organic Chemistry. 69:3025-3035
مصطلحات موضوعية: Lactams, Molecular Structure, Bicyclic molecule, Intramolecular reaction, Chemistry, Stereochemistry, Acylation, Organic Chemistry, Heteroatom, Stereoisomerism, Azepines, Bridged Bicyclo Compounds, Heterocyclic, Crystallography, X-Ray, Ring (chemistry), Azocines, Chemical synthesis, Cycloaddition, Cyclization, Intramolecular force, Oxazines, Hydrogenation, Nitroso Compounds, Diels–Alder reaction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe7c8081fcd83fbcfd86175c165b723Test
https://doi.org/10.1021/jo049897zTest -
10
المؤلفون: Kenneth J. Shea, Steven M. Sparks, Chun P. Chow
المصدر: Organic Letters. 4:2637-2640
مصطلحات موضوعية: Hydroxamic acid, Lactams, Bicyclic molecule, Stereochemistry, Organic Chemistry, Stereoisomerism, Biochemistry, chemistry.chemical_compound, chemistry, Intramolecular force, Stereoselectivity, Physical and Theoretical Chemistry, Nitroso Compounds, Diels–Alder reaction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1f856f7ae4484e7eb10289c33d8ea5Test
https://doi.org/10.1021/ol026075kTest