المؤلفون: Gong, Grace Q., Bilanges, Benoit, Allsop, Ben, Masson, Glenn R., Roberton, Victoria, Askwith, Trevor, Oxenford, Sally, Madsen, Ralitsa R., Conduit, Sarah E., Bellini, Dom, Fitzek, Martina, Collier, Matt, Najam, Osman, He, Zhenhe, Wahab, Ben, McLaughlin, Stephen H., Chan, A. W. Edith, Feierberg, Isabella, Madin, Andrew, Morelli, Daniele, Bhamra, Amandeep, Vinciauskaite, Vanesa, Anderson, Karen E., Surinova, Silvia, Pinotsis, Nikos, Lopez-Guadamillas, Elena, Wilcox, Matthew, Hooper, Alice, Patel, Chandni, Whitehead, Maria A., Bunney, Tom D., Stephens, Len R., Hawkins, Phillip T., Katan, Matilda, Yellon, Derek M., Davidson, Sean M., Smith, David M., Phillips, James B., Angell, Richard, Williams, Roger L., Vanhaesebroeck, Bart

المصدر: Gong , G Q , Bilanges , B , Allsop , B , Masson , G R , Roberton , V , Askwith , T , Oxenford , S , Madsen , R R , Conduit , S E , Bellini , D , Fitzek , M , Collier , M , Najam , O , He , Z , Wahab , B , McLaughlin , S H , Chan , A W E , Feierberg , I , Madin , A , Morelli , D , Bhamra , A , Vinciauskaite , V , Anderson , K E ....

مصطلحات موضوعية: Cell signalling, Drug discovery, Kinases, X-ray crystallography, /dk/atira/pure/subjectarea/asjc/1000, name=General

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/ecb2d398-f5df-47cc-8fd6-537759cc5e07Test

الإتاحة: https://doi.org/10.1038/s41586-023-05972-2Test
https://discovery.dundee.ac.uk/en/publications/ecb2d398-f5df-47cc-8fd6-537759cc5e07Test
https://discovery.dundee.ac.uk/ws/files/103607439/409738_4_merged_1678279284.pdfTest
http://www.scopus.com/inward/record.url?scp=85160229754&partnerID=8YFLogxKTest

المؤلفون: Chessa, Tamara A.M., Jung, Piotr, Anwar, Arqum, Suire, Sabine, Anderson, Karen E., Barneda, David, Kielkowska, Anna, Sadiq, Barzan A., Lai, Ieng Wai, Felisbino, Sergio, Turnham, Daniel J., Pearson, Helen B., Phillips, Wayne A., Sasaki, Junko, Sasaki, Takehiko, Oxley, David, Spensberger, Dominik, Segonds-Pichon, Anne, Wilson, Michael, Walker, Simon, Okkenhaug, Hanneke, Cosulich, Sabina, Hawkins, Phillip T., Stephens, Len R.

وصف الملف: application/pdf

العلاقة: https://orca.cardiff.ac.uk/id/eprint/161862/1/1-s2.0-S1097276523005580-main.pdfTest; Chessa, Tamara A.M., Jung, Piotr, Anwar, Arqum, Suire, Sabine, Anderson, Karen E., Barneda, David, Kielkowska, Anna, Sadiq, Barzan A., Lai, Ieng Wai, Felisbino, Sergio, Turnham, Daniel J. https://orca.cardiff.ac.uk/view/cardiffauthors/A1540438L.htmlTest orcid:0000-0002-2540-7363 orcid:0000-0002-2540-7363, Pearson, Helen B. https://orca.cardiff.ac.uk/view/cardiffauthors/A22687599.htmlTest orcid:0000-0002-3284-0843 orcid:0000-0002-3284-0843, Phillips, Wayne A., Sasaki, Junko, Sasaki, Takehiko, Oxley, David, Spensberger, Dominik, Segonds-Pichon, Anne, Wilson, Michael, Walker, Simon, Okkenhaug, Hanneke, Cosulich, Sabina, Hawkins, Phillip T. and Stephens, Len R. 2023. PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate. Molecular Cell 83 (16) , pp. 2991-3009. 10.1016/j.molcel.2023.07.015 https://doi.org/10.1016/j.molcel.2023.07.015Test file https://orca.cardiff.ac.uk/id/eprint/161862/1/1-s2.0-S1097276523005580-main.pdfTest

الإتاحة: https://doi.org/10.1016/j.molcel.2023.07.015Test
https://orca.cardiff.ac.uk/id/eprint/161862Test/
https://orca.cardiff.ac.uk/id/eprint/161862/1/1-s2.0-S1097276523005580-main.pdfTest

المؤلفون: Gong, Grace Q, Bilanges, Benoit, Allsop, Ben, Masson, Glenn R, Roberton, Victoria, Askwith, Trevor, Oxenford, Sally, Madsen, Ralitsa R, Conduit, Sarah E, Bellini, Dom, Fitzek, Martina, Collier, Matt, Najam, Osman, He, Zhenhe, Wahab, Ben, McLaughlin, Stephen H, Chan, AW Edith, Feierberg, Isabella, Madin, Andrew, Morelli, Daniele, Bhamra, Amandeep, Vinciauskaite, Vanesa, Anderson, Karen E, Surinova, Silvia, Pinotsis, Nikos, Lopez-Guadamillas, Elena, Wilcox, Matthew, Hooper, Alice, Patel, Chandni, Whitehead, Maria A, Bunney, Tom D, Stephens, Len R, Hawkins, Phillip T, Katan, Matilda, Yellon, Derek M, Davidson, Sean M, Smith, David M, Phillips, James B, Angell, Richard, Williams, Roger L, Vanhaesebroeck, Bart

المصدر: Nature , 618 pp. 159-168. (2023)

مصطلحات موضوعية: Cell signalling, Drug discovery, Kinases, X-ray crystallography

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10170780/15/Nature_manuscript_RPS.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10170780/12/SI%20Guide%20with%20tables%20and%20figures_new_upload.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10170780/8/Supplementary%20Table%201.xlsxTest; https://discovery.ucl.ac.uk/id/eprint/10170780/2/Supplementary%20Table%204.xlsTest; https://discovery.ucl.ac.uk/id/eprint/10170780/4/Supplementary%20Table%205.xlsTest; https://discovery.ucl.ac.uk/id/eprint/10170780/5/Supplementary%20Table%206.xlsTest; https://discovery.ucl.ac.uk/id/eprint/10170780/11/Supplementary%20Table%207.xlsxTest; https://discovery.ucl.ac.uk/id/eprint/10170780/6/Supplementary%20Table%208.xlsxTest; https://discovery.ucl.ac.uk/id/eprint/10170780/7/Supplementary%20Table%209.xlsxTest; https://discovery.ucl.ac.uk/id/eprint/10170780/9/Suppl%20Video%201_Activation_mechanisms.mp4Test; https://discovery.ucl.ac.uk/id/eprint/10170780/13/Suppl%20Video%202_A549_WT9_Veh_BYL_Pos18.aviTest; https://discovery.ucl.ac.uk/id/eprint/10170780/14/Suppl%20Video%203_A549_WT9_1938_BYL_Pos14.aviTest; https://discovery.ucl.ac.uk/id/eprint/10170780/10/Suppl%20Video%204_A549_KO12_1938_BYL_Pos0.aviTest; https://discovery.ucl.ac.uk/id/eprint/10170780Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10170780/15/Nature_manuscript_RPS.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10170780/12/SI%20Guide%20with%20tables%20and%20figures_new_upload.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10170780/8/Supplementary%20Table%201.xlsxTest
https://discovery.ucl.ac.uk/id/eprint/10170780/2/Supplementary%20Table%204.xlsTest
https://discovery.ucl.ac.uk/id/eprint/10170780/4/Supplementary%20Table%205.xlsTest
https://discovery.ucl.ac.uk/id/eprint/10170780/5/Supplementary%20Table%206.xlsTest
https://discovery.ucl.ac.uk/id/eprint/10170780/11/Supplementary%20Table%207.xlsxTest
https://discovery.ucl.ac.uk/id/eprint/10170780/6/Supplementary%20Table%208.xlsxTest
https://discovery.ucl.ac.uk/id/eprint/10170780/7/Supplementary%20Table%209.xlsxTest
https://discovery.ucl.ac.uk/id/eprint/10170780/9/Suppl%20Video%201_Activation_mechanisms.mp4Test

المؤلفون: Droubi, Alaa, Wallis, Connor, Anderson, Karen E, Rahman, Saifur, de Sa, Aloka, Rahman, Taufiq, Stephens, Len R, Hawkins, Philip T, Lowe, Martin

المصدر: Droubi , A , Wallis , C , Anderson , K E , Rahman , S , de Sa , A , Rahman , T , Stephens , L R , Hawkins , P T & Lowe , M 2022 , ' The inositol 5-phosphatase INPP5B regulates B cell receptor clustering and signaling ' , The Journal of cell biology , vol. 221 , no. 9 , e202112018 . https://doi.org/10.1083/jcb.202112018Test

العلاقة: https://research.manchester.ac.uk/en/publications/2dfef890-104b-4fbd-8291-adf28b076620Test

الإتاحة: https://doi.org/10.1083/jcb.202112018Test
https://research.manchester.ac.uk/en/publications/2dfef890-104b-4fbd-8291-adf28b076620Test

المؤلفون: Barneda, David, Janardan, Vishnu, Niewczas, Izabella, Collins, Daniel M, Cosulich, Sabina, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T

المساهمون: Biotechnology and Biological Sciences Research Council, National Centre for Biological Sciences, National University of Ireland

المصدر: The EMBO Journal ; volume 41, issue 18 ; ISSN 0261-4189 1460-2075

مصطلحات موضوعية: General Immunology and Microbiology, General Biochemistry, Genetics and Molecular Biology, Molecular Biology, General Neuroscience

الإتاحة: https://doi.org/10.15252/embj.2021110038Test

المؤلفون: Hoeller, Oliver, Bolourani, Parvin, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T, Weiner, Orion D, Weeks, Gerald, Kay, Robert R

المصدر: Journal of Cell Science. 126(18)

مصطلحات موضوعية: Genetics, Underpinning research, 1.1 Normal biological development and functioning, Actins, Chemotaxis, Humans, Phagocytosis, Phosphatidylinositol 3-Kinases, Pinocytosis, Signal Transduction, Dictyostelium, Macropinocytosis, PI3-kinase signalling, PtdIns(3, 4, 5)P-3, Ras, PtdIns(3, 4, 5)P3, Biological Sciences, Medical and Health Sciences, Developmental Biology

الوصول الحر: https://escholarship.org/uc/item/3wz4c3r3Test

المؤلفون: Luff, Daisy H., Wojdyla, Katarzyna, Oxley, David, Chessa, Tamara, Hudson, Kevin, Hawkins, Phillip T., Stephens, Len R., Barry, Simon T., Okkenhaug, Klaus

مصطلحات موضوعية: Immunology, PI3K, p110δ, TCR signalling, CD4+ T cells, interactomics, CRISPR-Cas9

وصف الملف: application/zip; text/xml; application/pdf; application/octet-stream

العلاقة: https://www.repository.cam.ac.uk/handle/1810/319026Test

الإتاحة: https://doi.org/10.17863/CAM.66145Test
https://www.repository.cam.ac.uk/handle/1810/319026Test

المؤلفون: Luff, Daisy H., Wojdyla, Katarzyna, Oxley, David, Chessa, Tamara, Hudson, Kevin, Hawkins, Phillip T., Stephens, Len R., Barry, Simon T., Okkenhaug, Klaus

المساهمون: Biotechnology and Biological Sciences Research Council, Wellcome Trust, Medical Research Council

المصدر: Frontiers in Immunology ; volume 12 ; ISSN 1664-3224

مصطلحات موضوعية: Immunology, Immunology and Allergy

الإتاحة: https://doi.org/10.3389/fimmu.2021.631271Test

المؤلفون: Bulley, Simon J., Droubi, Alaa, Clarke, Jonathan H., Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Irvine, Robin F.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2016 Sep . 113(38), 10571-10576.

الوصول الحر: https://www.jstor.org/stable/26471630Test

المؤلفون: Suire, Sabine, Baltanás, Fernando C., Segonds‐Pichon, Anne, Davidson, Keith, Santos de Dios, Eugenio, Hawkins, Phillip T., Stephens, Len R.

المساهمون: Biotechnology and Biological Sciences Research Council (UK)

مصطلحات موضوعية: PI3K, RasGEF, SOS

العلاقة: Publisher's version; http://dx.doi.org/10.1002/JLB.2HI0918-359RRTest; Sí; J Leukoc Biol. 106(4): 815-822 (2019); http://hdl.handle.net/10261/203265Test; http://dx.doi.org/10.13039/501100000268Test

الإتاحة: https://doi.org/10.1002/JLB.2HI0918-359RRTest
https://doi.org/10.13039/501100000268Test
http://hdl.handle.net/10261/203265Test