المؤلفون: Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, Olajumoke Adeniji-Popoola, Gary Box, Will Court, Stephanie Czasch, Samer El Bawab, Christina Esdar, Ken Ewan, Sharon Gowan, Alexis De Haven Brandon, Phillip Hewitt, Stephen M Hobbs, Wolfgang Kaufmann, Aurélie Mallinger, Florence Raynaud, Toby Roe, Felix Rohdich, Kai Schiemann, Stephanie Simon, Richard Schneider, Melanie Valenti, Stefan Weigt, Julian Blagg, Andree Blaukat, Trevor C Dale, Suzanne A Eccles, Stefan Hecht, Klaus Urbahns, Paul Workman, Dirk Wienke

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: CDK8, inhibitor, Mediator complex, Wnt, super-enhancer, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/20722Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/a201fbf6b4ca430996a70dd003f4f498Test

المؤلفون: Toby Roe, Will Court, Felix Rohdich, Julian Blagg, Wolfgang Kaufmann, Stefan Hecht, Richard Schneider, Stephen M. Hobbs, Christina Esdar, Alexis De Haven Brandon, Samer El Bawab, Phllip Hewitt, Suzanne A. Eccles, Kai Schiemann, Trevor Clive Dale, Paul Workman, Aurélie Mallinger, Stefan Weigt, Klaus Urbahns, Olajumoke Adeniji-Popoola, Andree Blaukat, Stephanie Simon, Robert TePoele, Melanie Valenti, Sharon Gowan, Stefanie Czasch, Paul A. Clarke, Gary Box, Dirk Wienke, Kenneth Burnside Ramsay Ewan, Maria-Jesus Ortiz-Ruiz, Florence I. Raynaud

المصدر: eLife
eLife, Vol 5 (2016)

مصطلحات موضوعية: 0301 basic medicine, Anti-Inflammatory Agents, Pharmacology, Mice, Neoplasms, Biology (General), media_common, Cancer Biology, Mediator Complex, Kinase, General Neuroscience, Wnt signaling pathway, General Medicine, Cyclin-Dependent Kinases, inhibitor, Treatment Outcome, Medicine, Heterografts, Stem cell, Research Article, Human, Drug, QH301-705.5, Science, media_common.quotation_subject, CDK8, Antineoplastic Agents, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Wnt, Immune system, Cyclin-dependent kinase, super-enhancer, medicine, Animals, Humans, Human Biology and Medicine, Protein Kinase Inhibitors, Hyperplasia, General Immunology and Microbiology, Cancer, medicine.disease, Cyclin-Dependent Kinase 8, Disease Models, Animal, 030104 developmental biology, Cancer cell, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320a3dd4067dcc727c7a6157a8004c42Test
http://europepmc.org/articles/PMC5224920Test

المؤلفون: Andree Blaukat, Sharon Gowan, Richard Schneider, Suzanne A. Eccles, Gary Box, Dirk Wienke, Paul Workman, Robert TePoele, Stefan Hecht, Kai Schiemann, Trevor Clive Dale, Paul A. Clarke, Melanie Valenti, Toby Roe, Felix Rohdich, Wolfgang Kaufmann, Stephanie Czasch, Maria-Jesus Ortiz-Ruiz, Christina Esdar, Stefan Weigt, Kenneth Burnside Ramsay Ewan, Aurélie Mallinger, Alexis De Haven Brandon, Phillip Hewitt, Olajumoke Adeniji-Popoola, Will Court, Florence I. Raynaud, Stephen M. Hobbs, Stephanie Simon, Julian Blagg, Samer El Bawab, Klaus Urbahns

مصطلحات موضوعية: Mediator, Chemistry, Kinase, Mechanism (biology), Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4fdc132145578e222df38589324159b5Test
https://doi.org/10.7554/elife.20722.047Test

المؤلفون: Michael I. Walton, Stephen M. Hobbs, Lloyd R. Kelland, Katharine Pestell, Jenny Titley

المصدر: Molecular Pharmacology. 57:503-511

مصطلحات موضوعية: DNA Repair, Organoplatinum Compounds, Population, Sulforhodamine B, Antineoplastic Agents, Apoptosis, Platinum Compounds, Transfection, DNA Adducts, chemistry.chemical_compound, Tumor Cells, Cultured, medicine, Humans, Cytotoxicity, Clonogenic assay, education, Ovarian Neoplasms, Pharmacology, Cisplatin, education.field_of_study, Chemistry, Cell Cycle, medicine.disease, Molecular biology, Cell culture, Immunology, Molecular Medicine, Female, Drug Screening Assays, Antitumor, Tumor Suppressor Protein p53, Ovarian cancer, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3c670e1c3144aa460071253ab8ce35Test
https://doi.org/10.1124/mol.57.3.503Test

المؤلفون: William R. Wilson, Alison Hogg, Kevin O. Hicks, Stephen M. Hobbs, Frederik B. Pruijn, Susan M. Pullen

مصطلحات موضوعية: Chemistry, In vivo, Genetic enhancement, Cytosine deaminase, Carboxypeptidase-G2, Bystander effect, Cancer research, Cytochrome P450 reductase, Suicide gene, Prodrug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::947db755e5851da369fce11e2c74f419Test
https://doi.org/10.1385/1-59259-429-8:403Test

المؤلفون: William R, Wilson, Susan M, Pullen, Alison, Hogg, Stephen M, Hobbs, Frederik B, Pruijn, Kevin O, Hicks

المصدر: Methods in molecular medicine. 90

مصطلحات موضوعية: Male, Cell Survival, Transplantation, Heterologous, Cell Culture Techniques, Genes, Transgenic, Suicide, Mice, Nude, Antineoplastic Agents, Genetic Therapy, Models, Biological, Coculture Techniques, Mice, Neoplasms, Tumor Cells, Cultured, Animals, Humans, Female, Prodrugs, Biotransformation, Cell Division

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c14609b08478f3d1e13aa6bc5436ea9aTest
https://pubmed.ncbi.nlm.nih.gov/14657576Test

المؤلفون: Matthew Bennett, Ulrich Baumann, David S. J. Gregory, M.R. Sanderson, Stephen M. Hobbs, David A. Suter, Stephen Neidle, Jane V. Skelly, Martin A. Read

المصدر: Journal of medicinal chemistry. 42(21)

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Aziridines, Molecular Sequence Data, Antineoplastic Agents, Crystallography, X-Ray, Oxidoreductase, Drug Discovery, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Prodrugs, Amino Acid Sequence, chemistry.chemical_classification, Binding Sites, biology, Substrate (chemistry), Active site, Prodrug, Rats, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb0e855fdb6ebdefc8ae1cf2a78d502Test
https://pubmed.ncbi.nlm.nih.gov/10543876Test

المؤلفون: Stephen M. Hobbs

المصدر: Immunochemical Protocols ISBN: 9780896034938

مصطلحات موضوعية: biology, Chemistry, law, biology.protein, Recombinant DNA, Antibody, Molecular biology, Fusion protein, law.invention

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfc857d6521e448a08f1fa43954656cTest
https://doi.org/10.1007/978-1-59259-257-9_42Test

المؤلفون: Helen P. Purvies, Suzanne A. Eccles, Stephen M. Hobbs, J Styles, C. J. Dean

المصدر: Cancer Immunology Immunotherapy. 30:13-20

مصطلحات موضوعية: Cancer Research, medicine.drug_class, Immunology, Spleen, Receptors, Fc, Monoclonal antibody, Iodine Radioisotopes, Immunoglobulin Fab Fragments, Immune system, Antigen, Antigens, Neoplasm, Immune Tolerance, medicine, Animals, Immunology and Allergy, Tissue Distribution, Receptor, biology, Chemistry, Age Factors, Antibodies, Monoclonal, Mononuclear phagocyte system, Molecular biology, Isotype, Rats, medicine.anatomical_structure, Oncology, Immunoglobulin G, biology.protein, Sarcoma, Experimental, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3bd69f6365d6763d830e873a8c9202Test
https://doi.org/10.1007/bf01665025Test