Comparison of lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis
| العنوان: | Comparison of lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis |
|---|---|
| المؤلفون: | Lotte Boxhoorn, Robert C Verdonk, Marc G Besselink, Marja Boermeester, Thomas L Bollen, Stefan AW Bouwense, Vincent C Cappendijk, Wouter L Curvers, Cornelis H Dejong, Sven M van Dijk, Hendrik M van Dullemen, Casper HJ van Eijck, Erwin JM van Geenen, Muhammed Hadithi, Wouter L Hazen, Pieter Honkoop, Jeanin E van Hooft, Maarten AJM Jacobs, June EC Kievits, Marnix PM Kop, Eva Kouw, Sjoerd D Kuiken, Michiel Ledeboer, Vincent B Nieuwenhuijs, Lars E Perk, Jan-Werner Poley, Rutger Quispel, Rogier JJ de Ridder, Hjalmar C van Santvoort, Christina J Sperna Weiland, Martijn WJ Stommel, Hester C Timmerhuis, Ben J Witteman, Devica S Umans, Niels G Venneman, Frank P Vleggaar, Roy LJ van Wanrooij, Marco J Bruno, Paul Fockens, Rogier P Voermans |
| المساهمون: | Gastroenterology and hepatology, Internal medicine, Gastroenterology & Hepatology, Surgery, Gastroenterology and Hepatology, Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, AII - Infectious diseases, Center for Liver, Digestive and Metabolic Diseases (CLDM), MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9) |
| المصدر: | Gut, 72, 1, pp. 66-72 Gut, 72(1):e22325632, 66-72. BMJ Publishing Group Boxhoorn, L, Verdonk, R C, Besselink, M G, Boermeester, M, Bollen, T L, Bouwense, S A, Cappendijk, V C, Curvers, W L, Dejong, C H, van Dijk, S M, van Dullemen, H M, van Eijck, C H, van Geenen, E J, Hadithi, M, Hazen, W L, Honkoop, P, van Hooft, J E, Jacobs, M A, Kievits, J E, Kop, M P, Kouw, E, Kuiken, S D, Ledeboer, M, Nieuwenhuijs, V B, Perk, L E, Poley, J-W, Quispel, R, de Ridder, R J, van Santvoort, H C, Sperna Weiland, C J, Stommel, M W, Timmerhuis, H C, Witteman, B J, Umans, D S, Venneman, N G, Vleggaar, F P, van Wanrooij, R L, Bruno, M J, Fockens, P & Voermans, R P 2022, ' Comparison of lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis ', Gut, vol. 72, no. 1, e22325632, pp. 66-72 . https://doi.org/10.1136/gutjnl-2021-325632Test Gut, 72(1), 66-72. BMJ Publishing Group Gut, 72, 66-72 Gut, 72(1). BMJ PUBLISHING GROUP Gut, 72, 66-72. BMJ PUBLISHING GROUP |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], All institutes and research themes of the Radboud University Medical Center, acute pancreatitis, DRAINAGE, Gastroenterology, MANAGEMENT, FLUID COLLECTIONS, Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0], endoscopy, GUIDELINES |
| الوصف: | ObjectiveLumen-apposing metal stents (LAMS) are believed to clinically improve endoscopic transluminal drainage of infected necrosis when compared with double-pigtail plastic stents. However, comparative data from prospective studies are very limited.DesignPatients with infected necrotising pancreatitis, who underwent an endoscopic step-up approach with LAMS within a multicentre prospective cohort study were compared with the data of 51 patients in the randomised TENSION trial who had been assigned to the endoscopic step-up approach with double-pigtail plastic stents. The clinical study protocol was otherwise identical for both groups. Primary end point was the need for endoscopic transluminal necrosectomy. Secondary end points included mortality, major complications, hospital stay and healthcare costs.ResultsA total of 53 patients were treated with LAMS in 16 hospitals during 27 months. The need for endoscopic transluminal necrosectomy was 64% (n=34) and was not different from the previous trial using plastic stents (53%, n=27)), also after correction for baseline characteristics (OR 1.21 (95% CI 0.45 to 3.23)). Secondary end points did not differ between groups either, which also included bleeding requiring intervention—5 patients (9%) after LAMS placement vs 11 patients (22%) after placement of plastic stents (relative risk 0.44; 95% CI 0.16 to 1.17). Total healthcare costs were also comparable (mean difference −€6348, bias-corrected and accelerated 95% CI −€26 386 to €10 121).ConclusionOur comparison of two patient groups from two multicentre prospective studies with a similar design suggests that LAMS do not reduce the need for endoscopic transluminal necrosectomy when compared with double-pigtail plastic stents in patients with infected necrotising pancreatitis. Also, the rate of bleeding complications was comparable. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0017-5749 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0232c66b1d6b27f21f30aaab8ed58472Test http://www.scopus.com/inward/record.url?scp=85132369581&partnerID=8YFLogxKTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0232c66b1d6b27f21f30aaab8ed58472 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00175749 |
|---|