المؤلفون: Fenwick, Michael K, Reers, Alexandra R, Liu, Yi, Zigweid, Rachael, Sankaran, Banumathi, Shin, Janis, Hulverson, Matthew A, Hammerson, Bradley, Álvaro, Elena Fernández, Myler, Peter J, Kaushansky, Alexis, Van Voorhis, Wesley C, Fan, Erkang, Staker, Bart L

المصدر: ACS Infectious Diseases. 9(10)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Digestive Diseases, Prevention, Infectious Diseases, Orphan Drug, Rare Diseases, Emerging Infectious Diseases, Vaccine Related, Immunization, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Child, Humans, Cryptosporidiosis, Cryptosporidium, Plasmodium, Drug Development, N-myristoyltransferase, childhood infectious disease, drug discovery, Medical microbiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/43f556fpTest

المؤلفون: Xie, Bin, Maker, Allison, Priest, Andrew V, Dranow, David M, Phan, Jenny N, Edwards, Thomas E, Staker, Bart L, Myler, Peter J, Gumbiner, Barry M, Sivasankar, Sanjeevi

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(32)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Generic health relevance, Cancer, Antibodies, Monoclonal, Cadherins, Cell Adhesion, Crystallography, X-Ray, Humans, Microscopy, Atomic Force, Molecular Dynamics Simulation, Protein Domains, E-cadherin, strand-swap dimer, antibody, 19A11, adhesion, strand–swap dimer

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1mq1h63tTest

المؤلفون: Rodríguez-Hernández, Diego, Fenwick, Michael K., Zigweid, Rachael, Sankaran, Banumathi, Myler, Peter J., Sunnerhagen, Per, Kaushansky, Alexis, Staker, Bart L., Grøtli, Morten

المساهمون: Vetenskapsr?det, National Institute of Allergy and Infectious Diseases, Swedish Foundation for International Cooperation in Research and Higher Education, U.S. Department of Health and Human Services, Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

المصدر: Journal of Medicinal Chemistry ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.4c00168Test

المؤلفون: Rodríguez-Hernández, Diego, Vijayan, Kamalakannan, Zigweid, Rachael, Fenwick, Michael K., Sankaran, Banumathi, Roobsoong, Wanlapa, Sattabongkot, Jetsumon, Glennon, Elizabeth K. K., Myler, Peter J., Sunnerhagen, Per, Staker, Bart L., Kaushansky, Alexis, Grøtli, Morten

المصدر: Nature Communications ; volume 14, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-023-41119-7Test
https://www.nature.com/articles/s41467-023-41119-7.pdfTest
https://www.nature.com/articles/s41467-023-41119-7Test

المؤلفون: Gu, Yushu, Liu, Miaomiao, Staker, Bart L., Buchko, Garry W., Quinn, Ronald J.

المساهمون: National Institute of Allergy and Infectious Diseases, National Health and Medical Research Council, Australian Research Council, Bill and Melinda Gates Foundation, Griffith University

المصدر: ACS Pharmacology & Translational Science ; volume 6, issue 4, page 578-586 ; ISSN 2575-9108 2575-9108

الإتاحة: https://doi.org/10.1021/acsptsci.2c00225Test

المؤلفون: Rodríguez-Hernández, Diego, Fenwick, Michael K., Zigweid, Rachael, Sankaran, Banumathi, Myler, Peter J., Sunnerhagen, Per, Kaushansky, Alexis, Staker, Bart L., Grøtli, Morten

المصدر: Journal of Medicinal Chemistry; 5/9/2024, Vol. 67 Issue 9, p7312-7329, 18p

المؤلفون: Helgren, Travis R, Chen, Congling, Wangtrakuldee, Phumvadee, Edwards, Thomas E, Staker, Bart L, Abendroth, Jan, Sankaran, Banumathi, Housley, Nicole A, Myler, Peter J, Audia, Jonathon P, Horn, James R, Hagen, Timothy J

المصدر: Bioorganic & Medicinal Chemistry. 25(3)

مصطلحات موضوعية: Biological Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Infectious Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Animals, Anti-Bacterial Agents, Cell Survival, Cells, Cultured, Dose-Response Relationship, Drug, Endothelial Cells, Enzyme Inhibitors, Methionyl Aminopeptidases, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, Pulmonary Artery, Rats, Rickettsia prowazekii, Structure-Activity Relationship, Epidemic typhus, Inhibition, Lung endothelial cells, MetAP, Metalloenzyme, Methionine aminopeptidase, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Biochemistry and cell biology, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7nh0n2pbTest

المؤلفون: Heindl, Miriam Ruth, Rupp, Anna-Lena, Schwerdtner, Marie, Bestle, Dorothea, Harbig, Anne, De Rocher, Amy, Schmacke, Luna C., Staker, Bart, Steinmetzer, Torsten, Stein, David A., Moulton, Hong M., Böttcher-Friebertshäuser, Eva

المساهمون: Subbarao, Kanta, Deutsche Forschungsgemeinschaft, State of Hesse LOEWE, HHS | NIH | National Institute of Allergy and Infectious Diseases

المصدر: Journal of Virology ; volume 98, issue 4 ; ISSN 0022-538X 1098-5514

الإتاحة: https://doi.org/10.1128/jvi.00102-24Test

المؤلفون: Gilleran, John A., Ashraf, Kutub, Delvillar, Melvin, Eck, Tyler, Fondekar, Raheel, Miller, Edward B., Hutchinson, Ashley, Dong, Aiping, Seitova, Alma, De Souza, Mariana Laureano, Augeri, David, Halabelian, Levon, Siekierka, John, Rotella, David P., Gordon, John, Childers, Wayne E., Grier, Mark C., Staker, Bart L., Roberge, Jacques Y., Bhanot, Purnima

المساهمون: Congressionally Directed Medical Research Programs, National Institutes of Health

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 5, page 3467-3503 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01795Test

المؤلفون: Ran, Xinping, Parikh, Prashit, Abendroth, Jan, Arakaki, Tracy L., Clifton, Matthew C., Edwards, Thomas E., Lorimer, Donald D., Mayclin, Stephen, Staker, Bart L., Myler, Peter, McLaughlin, Krystle J.

المصدر: Acta Crystallographica: Section F, Structural Biology Communications; Apr2024, Vol. 80 Issue 4, p82-91, 10p

مصطلحات موضوعية: MYCOBACTERIUM tuberculosis, DRUG development, DRUG target, DRUG resistance in microorganisms, DEATH rate, TUBERCULOSIS, NAD (Coenzyme)