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المؤلفون: Paul A. Dawson, Courtney B. Ferrebee
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)مصطلحات موضوعية: HNF4α, hepatocyte nuclear factor 4 alpha, OATP, organic anion transporting polypeptide, PPAR, peroxisome proliferator-activated receptor, Review, Intestinal absorption, G6Pase, glucose-6-phosphatase, LDL, low density lipoprotein, SREBP1c, sterol regulatory element binding protein-1c, DIO2, deiodinase 2, SHP, small heterodimer partner, NTCP, Na+-taurocholate transporting polypeptide, OST, organic solute transporter, Glucose homeostasis, General Pharmacology, Toxicology and Pharmaceutics, Enterohepatic circulation, FGFR4, fibroblast growth factor receptor 4, Bile acid, ACCII, acetyl-CoA carboxylase 2, G protein-coupled bile acid receptor, FAS, fatty acid synthase, Intestine, Transporters, GLP-1, glucagon-like polypeptide-1, Biochemistry, Liver, Cell signaling, medicine.drug_class, FXR, farnesoid X-receptor, TGR5, G-protein-coupled bile acid receptor, Biology, Cholesterol 7 alpha-hydroxylase, FOXO1, forkhead box protein O1, digestive system, PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1 alpha, VLDL, very low density lipoprotein, IBABP, ileal bile acid binding protein, medicine, T4, thyroid hormone, BSEP, bile salt export pump, lcsh:RM1-950, Lipid metabolism, CYP7A1, cholesterol 7α-hydroxylase, Bile acids, FGF, fibroblast growth factor, lcsh:Therapeutics. Pharmacology, APO, apolipoproteins, PEPCK, phosphoenolpyruvate carboxykinase, Energy homeostasis, ASBT, apical sodium-dependent bile acid transporter
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b1cfbf65891d85d42c0256c8af457Test
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المؤلفون: Jeffrey S. Flier, Bhavna N. Desai, Nicholas Douris, Marie L. Mather, Garima Singhal, Garret A. FitzGerald, Mikiko Watanabe, ffolliott M. Fisher, Hilde Vardeh, Imad Nasser, Thomas Lundasen, Eleftheria Maratos-Flier, Carsten Skarke, Darko Stevanovic, Andrew C. Adams
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1395-1406 (2017)مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, WT, wild type, Alcoholic liver disease, Cirrhosis, FGF21, FGF21, fibroblast growth factor 21, FGF21-OE, mice overexpressing the FGF21 gene, CPT1α, carnitine palmitoyltransferase 1 alpha, chemistry.chemical_compound, Mice, Random Allocation, ChREBPβ, carbohydrate-responsive element-binding protein beta, 0302 clinical medicine, CD68, cluster of differentiation 68, Longitudinal Studies, 2. Zero hunger, Liver injury, Mice, Knockout, Fatty liver, UCP2, uncoupling protein 2, Binge ethanol consumption, Chronic ethanol consumption, Molecular Biology, Cell Biology, FAS, fatty acid synthase, 3. Good health, Liver, Female, Original Article, IP, intraperitoneal, LDC, Lieber–DeCarli diet, Fatty Liver, Alcoholic, Adult, medicine.medical_specialty, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, Binge drinking, CYP2E1, cytochrome P450 family 2 subfamily E member 1, TNFα, tumor necrosis factor alpha, 030209 endocrinology & metabolism, SEM, standard error of the mean, MCP1, monocyte chemoattractant protein 1, ALDH1α1, aldehyde dehydrogenase 1 alpha 1, 03 medical and health sciences, Internal medicine, ALT, alanine aminotransferase, medicine, Animals, Humans, Ethanol metabolism, SREBP1c, sterol regulatory element-binding protein-1c, lcsh:RC31-1245, SCD1, stearoyl-CoA desaturase 1, Liver Diseases, Alcoholic, Ethanol, ADH 1 and 2, alcohol dehydrogenase 1 and 2, FGF21-KO, mice lacking the FGF21 gene, PPARα, peroxisome proliferator-activated receptor alpha, business.industry, medicine.disease, ACSS2, acyl-coenzyme a synthetase short-chain family member 2, Fibroblast Growth Factors, Mice, Inbred C57BL, SC, subcutaneous, 030104 developmental biology, Endocrinology, chemistry, CPT1β, carnitine palmitoyltransferase 1 beta, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87359866b7d7f6d8cdf13e1e0329e6c8Test
https://pubmed.ncbi.nlm.nih.gov/29107287Test -
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المؤلفون: Payam, Vahmani, William J, Meadus, Maria L P, da Silva, Alec D, Mitchell, Cletos, Mapiye, Pascale, Duff, David C, Rolland, Michael E R, Dugan
المصدر: Biochemistry and Biophysics Reports
مصطلحات موضوعية: Trans fatty acids, Cytotoxicity, SFA, saturated fatty acid, ACC, acetyl-CoA carboxylase, Ag+-SPE, silver ion solid phase extraction, c, cis, SREBP1c, sterol regulatory element-binding protein-1c, PUFA, polyunsaturated fatty acids, HT11, high-t11 fraction, TLC, thin layer chromatography, SCD1, stearoyl-CoA desaturase-1, FAS, fatty acid synthase, HMGCR, 3-Hydroxy-3-Methylglutaryl-CoA reductase, TG, triacylglycerol, HT10, high-t10 fraction, PL, phospholipid, Liver, Fatty acid metabolism, t, trans, SREBP2, sterol regulatory element-binding protein-2, BSA, bovine serum albumin, PHVO, partially hydrogenated vegetable oils, Cell culture, MUFA, monounsaturated fatty acids, Beef, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::456ff6d55cbd5c09b5dd109402952a42Test
https://pubmed.ncbi.nlm.nih.gov/28955893Test -
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المؤلفون: Kimberley D, Bruce, Dawid, Szczepankiewicz, Kiran K, Sihota, Manoj, Ravindraanandan, Hugh, Thomas, Karen A, Lillycrop, Graham C, Burdge, Mark A, Hanson, Christopher D, Byrne, Felino R, Cagampang
المصدر: Biochimica et Biophysica Acta
مصطلحات موضوعية: sirt1, sirtuin 1, NAFLD, non-alcoholic fatty liver disease, Aging, High fat, Photoperiod, NASH, non-alcoholic steatohepatitis, CLOCK Proteins, Receptors, Cytoplasmic and Nuclear, Development, Diet, High-Fat, Article, Mice, Sirtuin 1, NAD, nicotinamide adenine dinucleotide, Non-alcoholic Fatty Liver Disease, Pregnancy, Sirtuin 3, Fatty liver, Animals, Maternal diet, C, control, HF, high fat, Circadian, Nuclear Receptor Subfamily 1, Group F, Member 1, Clock, circadian locomotor output cycles kaput, Lipid Metabolism, Per2, Bmal1 (also called Arntl1), period 2, Circadian Rhythm, Mice, Inbred C57BL, Repressor Proteins, Cry2, cryptochrome 2, Srebp1c, sterol regulatory element binding protein-1c, Disease Models, Animal, Gene Expression Regulation, Liver, RORα, retinoic acid receptor-related orphan receptor alpha, Prenatal Exposure Delayed Effects, Nuclear Receptor Subfamily 1, Group D, Member 1, OPN, osteopontin, Female, Sterol Regulatory Element Binding Protein 1, Oxidation-Reduction, sirt3, sirtuin 3, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b2c49d25db7c5378cd179c13393d2008Test
https://pubmed.ncbi.nlm.nih.gov/27040510Test -
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المؤلفون: Christian Scherling, Rima Obeid, Jürgen Geisel, Hannelore Daniel, Stefanie Worsch, Bernhard L. Bader, Manuela Sailer, Jarlei Fiamoncini, Christoph Dahlhoff, Björn Hummel, Kirsten Uebel
المصدر: Molecular Metabolism
مصطلحات موضوعية: Hepatic steatosis, ACC, acetyl-CoA carboxylase, HFMS, methyl-donor supplemented high-fat diet, 3-HB, β-hydroxybutyrate, LDL, low density lipoprotein, PC, phosphatidylcholine, Cbs, cystathionine β-synthase, HF, high-fat diet, AMP-activated protein kinase, ANT, adenine nucleotide translocase, Beta oxidation, chemistry.chemical_classification, biology, C1, one-carbon, Fatty liver, VAT, visceral adipose tissue, SAM, S-adenosylmethionine, One-carbon metabolism, TG, triacylglycerol, ddc, Fatty acid synthase, Pemt, phosphatidylethanolamine methyltransferase, Original Article, β-HAD, β-hydroxyacyl CoA dehydrogenase, medicine.drug, MDS, methyl-donor supplementation, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, GNMT, glycine N-methyltransferase, C, control diet, Fasn, fatty acid synthase, HSP90, heat shock protein 90, Gapdh, glyceraldehyde 3-phosphate dehydrogenase, MTR, methionine synthase, VLDL, very low density lipoprotein, Internal medicine, NEFA, non-esterified fatty acids, medicine, Obesity, Carnitine, SREBP1c, sterol regulatory element-binding protein-1c, Bhmt, betaine-homocysteine methyltransferase, Molecular Biology, Acyl-carnitines, Cpt1a, carnitine palmitoyltransferase-1a, SM, sphingomyelin, CACT, carnitine-acylcarnitine transporter, SAH, S-adenosylhomocysteine, Fatty acid, AMPK, DIO, diet-induced obesity, PL, phospholipids, Cell Biology, Hcy, homocysteine, medicine.disease, AMPK, AMP-activated protein kinase, Endocrinology, PPARα, peroxisome proliferator-activated receptor-α, chemistry, MAT, methionine adenosyltransferase, HMW adiponectin, high molecular weight adiponectin, Hprt1, hypoxanthine phosphoribosyltransferase 1, MCD, malonyl-CoA decarboxylase, biology.protein, β-oxidation, PGC1α, peroxisome proliferator-activated receptor-γ co-activator-1α, CMS, methyl-donor supplemented control diet, Steatosis
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b838f623b7829f6d574d07dbed6c2ee8Test
https://mediatum.ub.tum.de/1516521Test -
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المؤلفون: Michael Trauner, Hanns-Ulrich Marschall, Curt Einarsson, Anders Thorell, Tatjana Stojakovic, Pooja Jha, Guenter Fauler, Thierry Claudel, Bastian Hoesel, Michaela Mueller, Harald Koefeler, Carolin Lackner
المصدر: Journal of Hepatology
مصطلحات موضوعية: vWAT, visceral white adipose tissue, C4, 7α-hydroxy-4-cholesten-3-one, FASN, fatty acid synthase, Receptors, Cytoplasmic and Nuclear, FGF19, SHP, small heterodimer partner, LDLR, low density lipoprotein receptor, chemistry.chemical_compound, SA, stearic acid, CA, cholic acid, TGs, triglycerides, Bile acid, Chemistry, ABC, ATP-binding cassette, MTTP, microsomal triglyceride transfer protein, Ursodeoxycholic Acid, FGF19, fibroblast growth factor 19, Ursodeoxycholic acid, Obesity, Morbid, 3. Good health, Stearoyl-CoA desaturase, HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase, lipids (amino acids, peptides, and proteins), Research Article, medicine.drug, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, MA, myristic acid, FAs, fatty acides, medicine.drug_class, NASH, non-alcoholic steatohepatitis, Cholesterol 7 alpha-hydroxylase, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, Bile Acids and Salts, PA, palmitic acid, FXR, farnesoid X receptor, nCEH, neutral cholesterol ester hydrolase, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, medicine, Humans, ApoB, apolipoprotein B, SREBP1c, sterol regulatory element-binding protein-1c, Liver X receptor, ComputingMethodologies_COMPUTERGRAPHICS, VLDL, very low density lipoproteins, Hepatology, BAs, bile acids, Lipogenesis, OA, oleic acid, Lipid metabolism, CYP7A1, cholesterol 7α-hydroxylase, Lipid Metabolism, FATP1, fatty acid transport protein 1, Endocrinology, 3-hydroxy-3-methylglutaryl-CoA reductase, Farnesoid X receptor, SCD, stearoyl-Coa desaturase, Non-alcoholic fatty liver disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd82151b619f124808fea36eb0c8125dTest