المؤلفون: Ong, Catherine W. M., Elkington, Paul T., Brilha, Sara, Ugarte-Gil, Cesar, Tome-Esteban, Maite T., Tezera, Liku B., Pabisiak, Przemyslaw J., Moores, Rachel C., Sathyamoorthy, Tarangini, Patel, Vimal, Gilman, Robert H., Porter, Joanna C., Friedland, Jon S.

مصطلحات موضوعية: Adult, Humans, Cohort Studies, Cells, Cultured, Host-Pathogen Interactions/drug effects, Active Transport, Cell Nucleus/drug effects, AMP-Activated Protein Kinases/metabolism, Enzyme Inhibitors/pharmacology, Extracellular Matrix Proteins/metabolism, Immunity, Innate/drug effects, Lung/drug effects/immunology/metabolism/pathology, Matrix Metalloproteinase 8/chemistry/metabolism, Mycobacterium tuberculosis/drug effects/immunology/physiology, Neutrophil Infiltration/drug effects, Neutrophils/enzymology/immunology/metabolism/pathology, NF-kappa B/metabolism, Phosphorylation/drug effects, Protein Processing, Post-Translational/drug effects, Proteolysis/drug effects, Respiratory Mucosa/drug effects/immunology/metabolism/pathology, Sputum/enzymology, Tuberculosis, Pulmonary/drug therapy/immunology/metabolism/pathology, https://purl.org/pe-repo/ocde/ford#3.02.00Test, https://purl.org/pe-repo/ocde/ford#3.01.09Test

العلاقة: urn:issn:1553-7374; https://hdl.handle.net/20.500.12866/5404Test; https://doi.org/10.1371/journal.ppat.1004917Test

الإتاحة: https://doi.org/20.500.12866/5404Test
https://doi.org/10.1371/journal.ppat.1004917Test
https://hdl.handle.net/20.500.12866/5404Test

المؤلفون: Catherine W.M. Ong, Joanna C. Porter, Vimal Patel, Maite Tome-Esteban, Przemyslaw J. Pabisiak, Liku B. Tezera, Robert H. Gilman, Tarangini Sathyamoorthy, Sara Brilha, Rachel Moores, Cesar Ugarte-Gil, Paul T. Elkington, Jon S. Friedland

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 11, Iss 5, p e1004917 (2015)

مصطلحات موضوعية: Neutrophils, AMP-Activated Protein Kinases, Cohort Studies, Neutrophils/enzymology/immunology/metabolism/pathology, Immunopathology, Lung/drug effects/immunology/metabolism/pathology, Neutrophil Infiltration/drug effects, Biology (General), Enzyme Inhibitors, Phosphorylation, Lung, Cells, Cultured, Enzyme Inhibitors/pharmacology, Extracellular Matrix Proteins, biology, NF-kappa B, Phosphorylation/drug effects, 3. Good health, medicine.anatomical_structure, Matrix Metalloproteinase 8, Respiratory Mucosa/drug effects/immunology/metabolism/pathology, Neutrophil Infiltration, Host-Pathogen Interactions, Tuberculosis, Pulmonary/drug therapy/immunology/metabolism/pathology, medicine.symptom, Host-Pathogen Interactions/drug effects, Sputum/enzymology, Research Article, Adult, Tuberculosis, QH301-705.5, Immunology, Active Transport, Cell Nucleus/drug effects, AMP-Activated Protein Kinases/metabolism, Active Transport, Cell Nucleus, Respiratory Mucosa, Microbiology, Extracellular Matrix Proteins/metabolism, Mycobacterium tuberculosis, Matrix Metalloproteinase 8/chemistry/metabolism, Virology, Immunity, Innate/drug effects, Genetics, medicine, Humans, Pulmonary pathology, Molecular Biology, Tuberculosis, Pulmonary, Protein Processing, Post-Translational/drug effects, Sputum, AMPK, Proteolysis/drug effects, Neutrophil extracellular traps, RC581-607, medicine.disease, biology.organism_classification, Immunity, Innate, purl.org/pe-repo/ocde/ford#3.01.09 [https], Mycobacterium tuberculosis/drug effects/immunology/physiology, NF-kappa B/metabolism, Proteolysis, Parasitology, Immunologic diseases. Allergy, Protein Processing, Post-Translational

وصف الملف: text; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadfd59053d4647b841ea3f9e873af4aTest
https://eprints.soton.ac.uk/377480Test/

المؤلفون: Pierre-Régis Burgel, Isabelle Sermet-Gaudelus, Louise Jeammet, Gérard Lambeau, Lhousseine Touqui, Dominique Leduc, Michel Chignard, Laurent Guillemot, Clémence Martin, Philippe Morand, Dorota Sands, Yongzheng Wu, Erwan Pernet

المساهمون: Défense innée et inflammation, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellule Pasteur UPMC, Institut Pasteur [Paris] (IP)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5), Service de pneumologie [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Service de Pneumologie et d'Allergologie Pédiatriques, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Régulation du transport anionique transépithélial : de la recherche fondamentale aux pathologies épithéliales (UMR_S 806), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Research Institute of Mother and Child [Warsaw, Poland], Service de Bactériologie [CHU Cochin, AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], This study was supported by France ‘Vaincre la Mucoviscidose’ and ‘DIM Malinf-Region Ile de France’ foundation., We thank Dr R. Ramphal (University of Florida, Gainesville, FL, USA), Dr T. Msadek (Institut Pasteur, Paris), Dr E. Pearlman (Case Western Reserve University, Cleveland, OH, USA), Dr J.C. Olson (West Virginia University, Morgantown, WV, USA), Dr P. Peris (University of València, Spain), Dr M. Gelb (University of Washington, Seattle, WA, USA) for providing PA and SA strains as well as substrate for sPLA2 activity assay and RO032007A compound, Dr C. Schmitt (Hôpital Trousseau, Paris) for providing expectorations of children patients, V. Balloy and M. Nahori (Institut Pasteur, Paris) for technical assistance with intratracheal and intravenous instillation and C. Payre for helpful advices in sPLA2 analyses., Wu, Yongzheng, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]-Sorbonne Université (SU), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)

المصدر: Nature Communications
Nature Communications, 2014, 5 (1), pp.5105. ⟨10.1038/ncomms6105⟩
Nature Communications, Nature Publishing Group, 2014, 5 (1), pp.5105. ⟨10.1038/ncomms6105⟩

مصطلحات موضوعية: Cystic Fibrosis, MESH: ADP Ribose Transferases, General Physics and Astronomy, MESH: Staphylococcus aureus / physiology, medicine.disease_cause, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Cystic fibrosis, Mice, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Child, MESH: Respiratory Mucosa, MESH: Animals, Child, ADP Ribose Transferases, MESH: Sputum / enzymology, 0303 health sciences, Multidisciplinary, MESH: Bronchi, respiratory system, 3. Good health, MESH: Young Adult, Staphylococcus aureus, Child, Preschool, Pseudomonas aeruginosa, Disease Progression, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Disease Progression, Adult, Host immunity, Adolescent, Bacterial Toxins, Guinea Pigs, Bronchi, Respiratory Mucosa, MESH: Epithelial Cells / enzymology, Biology, Group II Phospholipases A2, General Biochemistry, Genetics and Molecular Biology, MESH: Guinea Pigs, Microbiology, Young Adult, 03 medical and health sciences, MESH: Pseudomonas aeruginosa / physiology, medicine, Animals, Humans, MESH: Mice, [SDV.IMM.II] Life Sciences [q-bio]/Immunology/Innate immunity, 030304 developmental biology, MESH: Adolescent, Respiratory tract diseases, MESH: Humans, MESH: Group II Phospholipases A2 / metabolism, 030306 microbiology, MESH: Child, Preschool, Sputum, Epithelial Cells, MESH: Adult, General Chemistry, medicine.disease, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, respiratory tract diseases, MESH: Bacterial Toxins, Immunology, MESH: Cystic Fibrosis / enzymology, Bacterial infection, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Cystic Fibrosis / microbiology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f06fb088795a54d7501c15fac13411fTest
https://doi.org/10.1038/ncomms6105Test

المؤلفون: Pernet, Erwan, Guillemot, Laurent, Burgel, Pierre-Régis, Martin, Clémence, Lambeau, Gérard, Sermet-Gaudelus, Isabelle, Sands, Dorota, Leduc, Dominique, Morand, Philippe, Jeammet, Louise, Chignard, Michel, Wu, Yongzheng, Touqui, Lhousseine

المساهمون: Défense innée et inflammation, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellule Pasteur UPMC, Institut Pasteur Paris (IP)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5), Service de pneumologie CHU Cochin, Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Service de Pneumologie et d'Allergologie Pédiatriques, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Régulation du transport anionique transépithélial : de la recherche fondamentale aux pathologies épithéliales (UMR_S 806), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Research Institute of Mother and Child Warsaw, Poland, Service de Bactériologie CHU Cochin, AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin AP-HP, This study was supported by France ‘Vaincre la Mucoviscidose’ and ‘DIM Malinf-Region Ile de France’ foundation., We thank Dr R. Ramphal (University of Florida, Gainesville, FL, USA), Dr T. Msadek (Institut Pasteur, Paris), Dr E. Pearlman (Case Western Reserve University, Cleveland, OH, USA), Dr J.C. Olson (West Virginia University, Morgantown, WV, USA), Dr P. Peris (University of València, Spain), Dr M. Gelb (University of Washington, Seattle, WA, USA) for providing PA and SA strains as well as substrate for sPLA2 activity assay and RO032007A compound, Dr C. Schmitt (Hôpital Trousseau, Paris) for providing expectorations of children patients, V. Balloy and M. Nahori (Institut Pasteur, Paris) for technical assistance with intratracheal and intravenous instillation and C. Payre for helpful advices in sPLA2 analyses.

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: Bacterial infection, Respiratory tract diseases, MESH: ADP Ribose Transferases, MESH: Adolescent, MESH: Disease Progression, MESH: Epithelial Cells / enzymology, MESH: Group II Phospholipases A2 / metabolism, MESH: Guinea Pigs, MESH: Humans, MESH: Mice, MESH: Pseudomonas aeruginosa / physiology, MESH: Respiratory Mucosa, MESH: Sputum / enzymology, MESH: Staphylococcus aureus / physiology, MESH: Adult, MESH: Young Adult, MESH: Animals, MESH: Bacterial Toxins, MESH: Bronchi, MESH: Child, Preschool, MESH: Cystic Fibrosis / enzymology, MESH: Cystic Fibrosis / microbiology, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25290234; pasteur-02863033; https://pasteur.hal.science/pasteur-02863033Test; PUBMED: 25290234

الإتاحة: https://doi.org/10.1038/ncomms6105Test
https://pasteur.hal.science/pasteur-02863033Test

المؤلفون: Shum, DKY, Ip, MSM, Chan, SCH

مصطلحات موضوعية: Heparan sulfate proteoglycans, Proteinase, Secretory leukoproteinase inhibitor, α1-antitrypsin, Serine Proteinase Inhibitors - metabolism, Sputum - enzymology, Syndecan-1, Syndecans, alpha 1-Antitrypsin - metabolism, Leukocyte Elastase - metabolism, Proteinase Inhibitory Proteins, Secretory, Middle Aged, Humans, Heparitin Sulfate - metabolism, Female, Bronchiectasis - enzymology, Blotting, Western, Proteoglycans - metabolism, Membrane Glycoproteins - metabolism, Proteins - metabolism, Male

العلاقة: American Journal of Respiratory and Critical Care Medicine; http://www.scopus.com/mlt/select.url?eid=2-s2.0-0043033174&selection=ref&src=s&origin=recordpageTest; American Journal Of Respiratory And Critical Care Medicine, 2003, v. 168 n. 2, p. 192-198; 198; 95193; WOS:000184082000012; http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1073-449X&volume=168&issue=2&spage=192&epage=198&date=2003&atitleTest=Sputum+sol+neutrophil+elastase+activity+in+bronchiectasis:+differential+modulation+by+syndecan-1+; eid_2-s2.0-0043033174; 192; http://hdl.handle.net/10722/68227Test; 168

الإتاحة: https://doi.org/10.1164/rccm.200208-829OCTest
http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1073-449X&volume=168&issue=2&spage=192&epage=198&date=2003&atitleTest=Sputum+sol+neutrophil+elastase+activity+in+bronchiectasis:+differential+modulation+by+syndecan-1+
http://hdl.handle.net/10722/68227Test

المؤلفون: Chan, KN, Tsang, KW, Lam, WK, Ho, JCM, Ooi, GC, Zheng, L, Ho, PL

مصطلحات موضوعية: Adult, Aged, Bronchiectasis - Diagnosis - Enzymology, Female, Forced Expiratory Volume - Physiology, Humans, Inflammation Mediators - Metabolism, Male, Middle Aged, Pancreatic Elastase - Blood, Prospective Studies, Sputum - Enzymology, Vital Capacity - Physiology

العلاقة: Chest; http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033994202&selection=ref&src=s&origin=recordpageTest; Chest, 2000, v. 117 n. 2, p. 420-426; 426; 49985; WOS:000085449400024; eid_2-s2.0-0033994202; 420; http://hdl.handle.net/10722/157312Test; 117

الإتاحة: http://hdl.handle.net/10722/157312Test

المؤلفون: Park, H, Jung, K, Kim, H, Nahm, D, Kang, K

المساهمون: 101472, 101797, 박, 해심, 남, 동호

مصطلحات موضوعية: Adult, Asthma/chemically induced, Asthma/immunology, Bronchi/drug effects, Bronchi/secretion, Bronchoconstrictor Agents/pharmacology, Female, Humans, Interleukin-8/metabolism, Male, Methacholine Chloride/pharmacology, Middle Aged, Neutrophil Activation/drug effects, Occupational Diseases/chemically induced, Occupational Diseases/immunology, Peroxidase/metabolism, Sputum/enzymology, Sputum/immunology, Toluene 2,4-Diisocyanate/pharmacology, socio, psy

العلاقة: http://repository.ajou.ac.kr/handle/201003/4135Test

الإتاحة: http://repository.ajou.ac.kr/handle/201003/4135Test