المؤلفون: Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Pedersen, Mette L., Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Blech, Stefan, Schulz, Simone I., Cuyckens, Filip, Nguyen, Mai Anh, Scarfe, Graeme

المصدر: Clinical Pharmacology & Therapeutics ; volume 115, issue 5, page 931-938 ; ISSN 0009-9236 1532-6535

الإتاحة: https://doi.org/10.1002/cpt.3121Test

المؤلفون: Li, Wenkui, Vazvaei‐Smith, Faye, Dear, Gordon, Boer, Jason, Cuyckens, Filip, Fraier, Daniela, Liang, Yuexia, Lu, Ding, Mangus, Heidi, Moliner, Patricia, Pedersen, Mette Lund, Romeo, Andrea A., Spracklin, Douglas K., Wagner, David S., Winter, Serge, Xu, Xiaohui

المصدر: Clinical Pharmacology & Therapeutics; May2024, Vol. 115 Issue 5, p939-953, 15p

مصطلحات موضوعية: DRUG development, CONSORTIA, CLINICAL trials, DRUG registration, INVESTIGATIONAL drugs

المؤلفون: Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Pedersen, Mette L., Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Blech, Stefan, Schulz, Simone I., Cuyckens, Filip, Nguyen, Mai Anh, Scarfe, Graeme

المصدر: Clinical Pharmacology & Therapeutics; May2024, Vol. 115 Issue 5, p931-938, 8p

مصطلحات موضوعية: PHARMACOKINETICS, DRUG development, HUMAN beings, DECISION making

المؤلفون: Cuyckens, Filip, Hvenegaard, Mette G, Cassidy, Kenneth C, Spracklin, Douglas K, James, Alexander David, Pederson, Mette L, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A, Da-violante, Georges, Blech, Stefan, Hoffman, Matthew, Schulz, Simone, Moliner, Patricia, Young, Graeme C

العلاقة: Cuyckens, Filip, Hvenegaard, Mette G, Cassidy, Kenneth C, Spracklin, Douglas K, James, Alexander David, Pederson, Mette L, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A, Da-violante, Georges, Blech, Stefan, Hoffman, Matthew, Schulz, Simone, Moliner, Patricia and Young, Graeme C (2024) Recommendations on the Use of Multiple Labels in Human Mass Balance Studies. Drug metabolism and disposition: the biological fate of chemicals, 52 (3). pp. 153-158. ISSN 1521-009X

الإتاحة: https://doi.org/10.1124/dmd.123.001429Test
https://oak.novartis.com/51411Test/
https://dmd.aspetjournals.org/content/52/3/153Test

المؤلفون: Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Scarfe, Graeme, Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, van Groen, Bianca, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Bister, Bojan, Blech, Stefan, Lyer, Ramaswamy, Schulz, Simone I., Cuyckens, Filip, Moliner, Patricia

المصدر: Clinical Pharmacology & Therapeutics ; volume 113, issue 4, page 775-781 ; ISSN 0009-9236 1532-6535

الإتاحة: https://doi.org/10.1002/cpt.2691Test

المؤلفون: Spracklin, Douglas K.

وصف الملف: 4321238 bytes; application/pdf

الإتاحة: http://hdl.handle.net/2429/8971Test

المؤلفون: Spracklin, Douglas K., Chen, Danny, Bergman, Arthur J., Callegari, Ernesto, Obach, R. Scott

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 9, issue 8, page 428-434 ; ISSN 2163-8306 2163-8306

الإتاحة: https://doi.org/10.1002/psp4.12540Test

المؤلفون: Li, Wenkui, Vazvaei-Smith, Faye, Dear, Gordon, Boer, Jason, Cuyckens, Filip, Fraier, Daniela, Liang, Yuexia, Lu, Ding, Mangus, Heidi, Moliner, Patricia, Pedersen, Mette L., Romeo, Andrea A., Spracklin, Douglas K., Wagner, David S., Winter, Serge, Xu, Xiaohui (Sophia)

العلاقة: Li, Wenkui, Vazvaei-Smith, Faye, Dear, Gordon, Boer, Jason, Cuyckens, Filip, Fraier, Daniela, Liang, Yuexia, Lu, Ding, Mangus, Heidi, Moliner, Patricia, Pedersen, Mette L., Romeo, Andrea A., Spracklin, Douglas K., Wagner, David S., Winter, Serge and Xu, Xiaohui (Sophia) (2023) Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group. Clinical Pharmacology & Therapeutics. ISSN 0009-92361532-6535

الإتاحة: https://doi.org/10.1002/cpt.3144Test
https://oak.novartis.com/49727Test/

المؤلفون: Khojasteh, S Cyrus, Argikar, Upendra A, Driscoll, James P, Heck, Carley JS, King, Lloyd, Jackson, Klarissa D, Jian, Wenying, Kalgutkar, Amit S, Miller, Grover P, Kramlinger, Valerie, Rietjens, Ivonne MCM, Teitelbaum, Aaron M, Wang, Kai, Wei, Cong, Johnson, Benjamin M, Shu, Yue-Zhong, Zhuo, Xiaoliang, Meanwell, Nicholas A, Cerny, Matthew A, Obach, R Scott, Sharma, Raman, Spracklin, Douglas K, Walker, Gregory S, Goracci, Laura, Desantis, Jenny, Valeri, Aurora, Castellani, Beatrice, Eleuteri, Michela, Cruciani, Gabriele, Lall, Manjinder S, Bassyouni, Asser, Bradow, James, Brown, Maria, Bundesmann, Mark, Chen, Jinshan, Ciszewski, Gregory, Hagen, Anne E, Hyek, Dennis, Jenkinson, Stephen, Liu, Bo, Pan, Senliang, Reilly, Usa, Sach, Neal, Smaltz, Daniel J, Starr, Jeremy, Wagenaar, Melissa, de Bruyn Kops, Christina, Sicho, Martin, Mazzolari, Angelica, Kirchmair, Johannes, Korprasertthaworn, Porntipa, Chau, Nuy, Nair, Pramod C, Rowland, Andrew, Miners, John O, Wrobleski, Stephen T, Moslin, Ryan, Lin, Shuqun, Zhang, Yanlei, Spergel, Steven, Kempson, James, Tokarski, John S, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Shuster, David, Gillooly, Kathleen, Yang, Xiaoxia, Heimrich, Elizabeth, McIntyre, Kim W, Chaudhry, Charu, Khan, Javed, Ruzanov, Max, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Sun, Huadong, Huang, Christine, D'Arienzo, Celia, Aranibar, Nelly, Chiney, Manoj, Chimalakonda, Anjaneya, Pitts, William J, Lombardo, Louis, Carter, Percy H, Burke, James R, Weinstein, David S, Li, Jing, Liu, Ju, Enders, Jennifer, Arciprete, Michael, Tran, Chris, Aluri, Krishna, Guan, Li-Hua, O'Shea, Jonathan, Bisbe, Anna, Charisse, Klaus, Zlatev, Ivan, Najarian, Diana, Xu, Yuanxin, Kim, Jaeah, El Zahar, Noha M, Bartlett, Michael G, Katyayan, Kishore, Yi, Ping, Monk, Scott, Cassidy, Kenneth, Takahashi, Ryan H, Grandner, Jessica M, Bobba, Sudheer, Liu, Yanzhou, Beroza, Paul, Zhang, Donglu, Ma, Shuguang, Post, Noah, Yu, Rosie, Greenlee, Sarah, Gaus, Hans, Hurh, Eunju, Matson, John, Wang, Yanfeng, Tajima, Yuya, Toyoda, Takeshi, Hirayama, Yuichiro, Matsushita, Kohei, Yamada, Takanori, Ogawa, Kumiko, Watanabe, Kenji, Takamura-Enya, Takeji, Totsuka, Yukari, Wakabayashi, Keiji, Miyoshi, Noriyuki, Zhang, Jiayin, Chan, Chi-Kong, Ham, Yat-Hing, Chan, Wan, Schleiff, Mary Alexandra, Flynn, Noah R, Payakachat, Sasin, Schleiff, Benjamin Mark, Pinson, Anna O, Province, Dennis W, Swamidass, S Joshua, Boysen, Gunnar, Nardone-White, Dasean T, Bissada, Jennifer E, Abouda, Arsany A, Zhang, Zhuming, Connolly, Peter J, Lim, Heng Keang, Pande, Vineet, Meerpoel, Lieven, Teleha, Christopher, Branch, Jonathan R, Ondrus, Janine, Hickson, Ian, Bush, Tammy, Luistro, Leopoldo, Packman, Kathryn, Bischoff, James R, Ibrahim, Salam, Parrett, Christopher, Chong, Yolanda, Gottardis, Marco M, Bignan, Gilles, Mulder, Teresa, Bobba, Sudder, Johnson, Kevin M, Wang, Wei, Zhang, Chenghong, Cai, Jingwei, Choo, Edna F, Crawford, James J, Landry, Matthew L, Chen, Huifen, Kenny, Jane R, Lee, Wendy, Young, Wendy B, Geib, Timon, Thulasingam, Madhuranayaki, Haeggstrom, Jesper Z, Sleno, Lekha, Monroe, James J, Tanis, Keith Q, Podtelezhnikov, Alexei A, Nguyen, Truyen, Machotka, Sam V, Lynch, Donna, Evers, Raymond, Palamanda, Jairam, Miller, Randy R, Pippert, Todd, Cabalu, Tamara D, Johnson, Timothy E, Aslamkhan, Amy G, Kang, Wen, Tamburino, Alex M, Mitra, Kaushik, Agrawal, Nancy GB, Sistare, Frank D

المصدر: Drug Metabolism Reviews 53 (2021) 3
Drug Metabolism Reviews, 53(3), 384-433

مصطلحات موضوعية: METABOLISM, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, nonp450 enzymes, 0302 clinical medicine, p450 enzymes, Biotransformation, INTRINSIC CLEARANCE, Political science, MASS-BALANCE, Humans, Pharmacology (medical), Pharmacology & Pharmacy, P450 Enzymes, General Pharmacology, Toxicology and Pharmaceutics, ANTISENSE OLIGONUCLEOTIDE, Toxicologie, VLAG, ARISTOLOCHIC ACID, Drug metabolism, Science & Technology, WIMEK, bioactivation, IDENTIFICATION, Year in review, IN-VITRO, NONHEPATOTOXIC DRUGS, Drug metabolizing enzymes, Drug development, 030220 oncology & carcinogenesis, COVALENT BINDING DATA, Engineering ethics, biotransformation, LIVER-MICROSOMES, Life Sciences & Biomedicine

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a22a3073b1b8be7c5621703d8a65f67Test
https://doi.org/10.1080/03602532.2021.1916028Test

المؤلفون: Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Scarfe, Graeme, Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, van Groen, Bianca, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Bister, Bojan, Blech, Stefan, Lyer, Ramaswamy, Schulz, Simone I., Cuyckens, Filip, Moliner, Patricia

المصدر: Clinical Pharmacology & Therapeutics; Apr2023, Vol. 113 Issue 4, p775-781, 7p

مصطلحات موضوعية: PAPER industry, CLINICAL pharmacology, SMALL molecules, HUMAN beings, PHARMACEUTICAL industry