المؤلفون: Fenix, Aidan M, Miyaoka, Yuichiro, Bertero, Alessandro, Blue, Steven M, Spindler, Matthew J, Tan, Kenneth KB, Perez-Bermejo, Juan A, Chan, Amanda H, Mayerl, Steven J, Nguyen, Trieu D, Russell, Caitlin R, Lizarraga, Paweena P, Truong, Annie, So, Po-Lin, Kulkarni, Aishwarya, Chetal, Kashish, Sathe, Shashank, Sniadecki, Nathan J, Yeo, Gene W, Murry, Charles E, Conklin, Bruce R, Salomonis, Nathan

المصدر: Nature Communications. 12(1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Rare Diseases, Heart Disease, Genetics, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, Cardiomyopathies, Cardiomyopathy, Dilated, DEAD-box RNA Helicases, DNA Helicases, Gain of Function Mutation, Gene Knockdown Techniques, Humans, Induced Pluripotent Stem Cells, Male, Mutation, Mutation, Missense, Poly-ADP-Ribose Binding Proteins, Proto-Oncogene Proteins, RNA Helicases, RNA Recognition Motif Proteins, RNA Splicing, RNA-Binding Proteins, Ribonucleoproteins

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7rs018c6Test

المؤلفون: Heather, James M, Spindler, Matthew J, Alonso, Marta Herrero, Shui, Yifang Ivana, Millar, David G, Johnson, David S, Cobbold, Mark, Hata, Aaron N

المساهمون: NIH/NCI, NIH/NIAID, Emily Venanzi Fund for Innovation in Lung Cancer Research

المصدر: Nucleic Acids Research ; volume 50, issue 12, page e68-e68 ; ISSN 0305-1048 1362-4962

الإتاحة: https://doi.org/10.1093/nar/gkac190Test
https://academic.oup.com/nar/article-pdf/50/12/e68/44449869/gkac190.pdfTest

المؤلفون: Taglieri, Domenico M, Johnson, Keven R, Burmeister, Brian T, Monasky, Michelle M, Spindler, Matthew J, DeSantiago, Jaime, Banach, Kathrin, Conklin, Bruce R, Carnegie, Graeme K

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Hypertension, Heart Disease, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, A Kinase Anchor Proteins, Angiotensin II, Animals, Aorta, Apoptosis, Cardiomegaly, Collagen, Female, Gene Expression Regulation, Guanine Nucleotide Exchange Factors, Heart Failure, Histone Deacetylases, Male, Mice, Mice, Transgenic, Minor Histocompatibility Antigens, Myocardium, Phenylephrine, Protein Kinase C, Protein Structure, Tertiary, Signal Transduction, A-Kinase Anchoring Protein, Protein kinase D, Cardiac hypertrophy, Heart failure, 1M, AT-II, E/A ratio, EDT, EDV, EF, ET1, FS, G protein coupled receptor, GPCR, HDAC5, HOP, HW/BW, LV, LVAWD, LVPWD, PE, PKA, PKC, PKD, TAC, WT, angiotensin II, early (E) to late (atrial A) ventricular filling velocity ratio, ejection fraction, end-diastolic volume, endothelin1, fractional shortening, heart weight to body weight ratio, histone deacetylase 5, hydroxyproline, left ventricular diastolic anterior wall thickness, left ventricular diastolic posterior wall thickness, left ventricular/ventricle, one month, phenylephrine, protein kinase A, protein kinase C, protein kinase D, transmitral early filling deceleration time, transverse aortic constriction, wild type, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Biochemistry and cell biology, Cardiovascular medicine and haematology, Medical physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/18m8880gTest

المؤلفون: Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Lim, Yoong Wearn, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Lundberg, Carina Vingsbo, Büscher, Dirk, Terencio, Jose Vicente, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V. F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.

المساهمون: National Science Foundation, U.S. Department of Health & Human Services | National Institutes of Health

المصدر: Nature Biotechnology ; volume 39, issue 8, page 989-999 ; ISSN 1087-0156 1546-1696

مصطلحات موضوعية: Biomedical Engineering, Molecular Medicine, Applied Microbiology and Biotechnology, Bioengineering, Biotechnology

الإتاحة: https://doi.org/10.1038/s41587-021-00894-8Test
https://www.nature.com/articles/s41587-021-00894-8.pdfTest
https://www.nature.com/articles/s41587-021-00894-8Test

المؤلفون: Kreitzer, Faith R, Salomonis, Nathan, Sheehan, Alice, Huang, Miller, Park, Jason S, Spindler, Matthew J, Lizarraga, Paweena, Weiss, William A, So, Po-Lin, Conklin, Bruce R

المصدر: American Journal of Stem Cells. 2(2)

مصطلحات موضوعية: Pediatric Research Initiative, Stem Cell Research - Embryonic - Human, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Pediatric, Neurosciences, Regenerative Medicine, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Neural crest, induced pluripotent stem cells, human, SMAD inhibition, differentiation, migration

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/061156rtTest

المؤلفون: Spindler, Matthew J, Burmeister, Brian T, Huang, Yu, Hsiao, Edward C, Salomonis, Nathan, Scott, Mark J, Srivastava, Deepak, Carnegie, Graeme K, Conklin, Bruce R

المصدر: PloS one. 8(4)

مصطلحات موضوعية: Heart, Animals, Mice, Transgenic, Mice, Cardiomegaly, Isoproterenol, Guanine Nucleotide Exchange Factors, Minor Histocompatibility Antigens, Stroke Volume, Electrocardiography, Organ Size, Breeding, Signal Transduction, Gene Expression Regulation, Developmental, Protein Structure, Tertiary, Myocardial Contraction, Female, Male, Embryo, Mammalian, A Kinase Anchor Proteins, Transgenic, Gene Expression Regulation, Developmental, Protein Structure, Tertiary, Embryo, Mammalian, General Science & Technology

الوصول الحر: https://escholarship.org/uc/item/3rb8516tTest

المؤلفون: Spindler, Matthew J., Nelson, Ayla L., Wagner, Ellen K., Oppermans, Natasha, Bridgeman, John S., Heather, James M., Adler, Adam S., Asensio, Michael A., Edgar, Robert C., Lim, Yoong Wearn, Meyer, Everett H., Hawkins, Robert E., Cobbold, Mark, Johnson, David S.

المصدر: Spindler , M J , Nelson , A L , Wagner , E K , Oppermans , N , Bridgeman , J S , Heather , J M , Adler , A S , Asensio , M A , Edgar , R C , Lim , Y W , Meyer , E H , Hawkins , R E , Cobbold , M & Johnson , D S 2020 , ' Massively parallel interrogation and mining of natively paired human TCRαβ repertoires ' , Nature biotechnology , vol. 38 , no. 5 , pp. 609-619 . https://doi.org/10.1038/s41587-020-0438-yTest

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1038/s41587-020-0438-yTest
https://research.manchester.ac.uk/en/publications/1cee39a5-c306-4ddf-ae14-d27be20c8975Test
http://www.scopus.com/inward/record.url?scp=85082685163&partnerID=8YFLogxKTest

المؤلفون: Asensio, Michael A., Lim, Yoong Wearn, Wayham, Nicholas, Stadtmiller, Kacy, Edgar, Robert C., Leong, Jackson, Leong, Renee, Mizrahi, Rena A., Adams, Matthew S., Simons, Jan Fredrik, Spindler, Matthew J., Johnson, David S., Adler, Adam S.

المساهمون: National Cancer Institute

المصدر: mAbs ; volume 11, issue 5, page 870-883 ; ISSN 1942-0862 1942-0870

الإتاحة: https://doi.org/10.1080/19420862.2019.1583995Test

المؤلفون: Adler, Adam S., Bedinger, Daniel, Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Renee, Leong, Jackson, Mizrahi, Rena A., Spindler, Matthew J., Bandi, Srinivasa Rao, Huang, Haichun, Tawde, Pallavi, Brams, Peter, Johnson, David S.

المساهمون: National Cancer Institute, National Science Foundation

المصدر: mAbs ; volume 10, issue 3, page 431-443 ; ISSN 1942-0862 1942-0870

الإتاحة: https://doi.org/10.1080/19420862.2018.1426422Test

المؤلفون: Adler, Adam S., Mizrahi, Rena A., Spindler, Matthew J., Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Roalfe, Lucy, White, Rebecca, Goldblatt, David, Johnson, David S.

المصدر: mAbs ; volume 9, issue 8, page 1282-1296 ; ISSN 1942-0862 1942-0870

الإتاحة: https://doi.org/10.1080/19420862.2017.1371383Test