المؤلفون: Ghosh, Ujjayini, Tse, Eric, Yang, Hyunjun, Shi, Marie, Caro, Christoffer D, Wang, Feng, Merz, Gregory E, Prusiner, Stanley B, Southworth, Daniel R, Condello, Carlo

المصدر: Acta Neuropathologica Communications. 12(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Brain Disorders, Dementia, Neurodegenerative, Neurosciences, Down Syndrome, Aging, Alzheimer's Disease, Intellectual and Developmental Disabilities (IDD), 2.1 Biological and endogenous factors, Aetiology, Neurological, Humans, tau Proteins, Cryoelectron Microscopy, Middle Aged, Alzheimer Disease, Female, Adult, Male, Neurofibrillary Tangles, Brain, Down syndrome, Alzheimer's disease, Tauopathy, Protein conformation, Cryo-electron microscopy, Alzheimer’s disease, Cryo–electron microscopy, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/77j5m9kmTest
https://escholarship.org/content/qt77j5m9km/qt77j5m9km.pdfTest

المؤلفون: Braxton, Julian R, Altobelli, Chad R, Tucker, Maxwell R, Tse, Eric, Thwin, Aye C, Arkin, Michelle R, Southworth, Daniel R

المصدر: Nature Structural & Molecular Biology. 30(12)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Underpinning research, 1.1 Normal biological development and functioning, Humans, Valosin Containing Protein, Protein Binding, Protein Structure, Tertiary, Cell Cycle Proteins, Chemical Sciences, Medical and Health Sciences, Biophysics, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7c6098r0Test

المؤلفون: Merz, Gregory E, Chalkley, Matthew J, Tan, Sophia K, Tse, Eric, Lee, Joanne, Prusiner, Stanley B, Paras, Nick A, DeGrado, William F, Southworth, Daniel R

المصدر: Nature Communications. 14(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Aging, Neurosciences, Brain Disorders, Bioengineering, Alzheimer's Disease, Neurodegenerative, Dementia, Aetiology, 2.1 Biological and endogenous factors, Generic health relevance, Neurological, Humans, Alzheimer Disease, Amyloid, Cryoelectron Microscopy, Ligands, tau Proteins

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/48h9q2f7Test

المؤلفون: Cupo, Ryan R, Rizo, Alexandrea N, Braun, Gabriel A, Tse, Eric, Chuang, Edward, Gupta, Kushol, Southworth, Daniel R, Shorter, James

المصدر: Cell reports. 40(13)

مصطلحات موضوعية: Humans, Nucleotides, Ankyrins, Heat-Shock Proteins, Adenosine Triphosphate, Protein Transport, Models, Molecular, AAA+ proteins, protein aggregation, CP: Cell biology, chaperone, disaggregase, mitochondria, mitochondrial disorders, therapeutics, 1.1 Normal biological development and functioning, Aetiology, Underpinning research, 2.1 Biological and endogenous factors, Biochemistry and Cell Biology, Medical Physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/40d0815cTest

المؤلفون: Felker, Dana, Lee, Kanghyun, Pospiech, Thomas H., Morishima, Yoshihiro, Zhang, Haoming, Lau, Miranda, Southworth, Daniel R., Osawa, Yoichi

المساهمون: National Institute of Environmental Health Sciences, Medical School, University of Michigan, National Institutes of Health, National Institute of General Medical Sciences

المصدر: Journal of Biological Chemistry ; volume 300, issue 1, page 105464 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1016/j.jbc.2023.105464Test
https://api.elsevier.com/content/article/PII:S0021925823024924?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925823024924?httpAccept=text/plainTest

المؤلفون: Lee, Kanghyun, Thwin, Aye C, Nadel, Cory M, Tse, Eric, Gates, Stephanie N, Gestwicki, Jason E, Southworth, Daniel R

المصدر: Molecular Cell. 81(17)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Underpinning research, 1.1 Normal biological development and functioning, Amino Acid Sequence, Binding Sites, Biomarkers, Tumor, Cryoelectron Microscopy, HSP90 Heat-Shock Proteins, Humans, Molecular Chaperones, Molecular Conformation, Protein Binding, Tacrolimus Binding Proteins, Tumor Protein, Translationally-Controlled 1, FKBP51, Hsp90, cryo-electron microscopy, heat shock proteins, immunophilins, molecular chaperones, p23, peptidyl-prolyl isomerase, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/25384958Test

المؤلفون: Gupta, Meghna, Azumaya, Caleigh M, Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E, Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F, Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T, Lam, Victor L, Li, Fei, Li, Yang, Nguyen, Henry C, Nowotny, Carlos, Owens, Tristan W, Peters, Jessica K, Rizo, Alexandrea N, Schulze-Gahmen, Ursula, Smith, Amber M, Young, Iris D, Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G, Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E, Mancino, Adamo, Moss, Frank R, Paul, Michael D, Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H, Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C, Titus, Erron W, Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Consortium, QCRG Structural Biology, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R, Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A

المصدر: bioRxiv. 2(05-19)

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Pneumonia, Emerging Infectious Diseases, Biodefense, Vaccine Related, Infectious Diseases, Prevention, Pneumonia & Influenza, Lung, Aetiology, Underpinning research, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Infection, Generic health relevance

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3rr259j7Test

المؤلفون: Lopez, Kyle E, Rizo, Alexandrea N, Tse, Eric, Lin, JiaBei, Scull, Nathaniel W, Thwin, Aye C, Lucius, Aaron L, Shorter, James, Southworth, Daniel R

المصدر: Nature Structural & Molecular Biology. 27(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Generic health relevance, Adenosine Triphosphate, Cryoelectron Microscopy, DNA Helicases, Endopeptidase Clp, Escherichia coli, Escherichia coli Proteins, Models, Molecular, Multiprotein Complexes, Protein Conformation, Protein Unfolding, Trans-Activators, Chemical Sciences, Medical and Health Sciences, Biophysics, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0bh0d37vTest

المؤلفون: Chen, John J, Nathaniel, Diane L, Raghavan, Preethi, Nelson, Maxine, Tian, Ruilin, Tse, Eric, Hong, Jason Y, See, Stephanie K, Mok, Sue-Ann, Hein, Marco Y, Southworth, Daniel R, Grinberg, Lea T, Gestwicki, Jason E, Leonetti, Manuel D, Kampmann, Martin

المصدر: Journal of Biological Chemistry. 294(50)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Aging, Neurodegenerative, Alzheimer's Disease Related Dementias (ADRD), Dementia, Alzheimer's Disease, Neurosciences, Acquired Cognitive Impairment, Brain Disorders, Frontotemporal Dementia (FTD), Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Genetics, Rare Diseases, Aetiology, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Underpinning research, Generic health relevance, Neurological, Cells, Cultured, Endosomal Sorting Complexes Required for Transport, HEK293 Cells, Humans, Lysosomes, Protein Aggregates, tau Proteins, CRISPR/Cas, Membrane damage, Tau protein, endosomal sorting complexes required for transport, endosome, fluorescence resonance energy transfer, functional genomics, lysosome, protein aggregation, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5nx3v7pxTest
https://escholarship.org/content/qt5nx3v7px/qt5nx3v7px.pdfTest

المؤلفون: Shorter, James, Southworth, Daniel R

المصدر: Cold Spring Harbor Perspectives in Biology. 11(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Generic health relevance, Adenosine Triphosphatases, Adenosine Triphosphate, Cryoelectron Microscopy, Glycoside Hydrolases, Heat-Shock Proteins, Hydrolysis, Molecular Chaperones, Prions, Protein Binding, Protein Conformation, Protein Transport, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Biochemistry and cell biology, Genetics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0m5276c6Test