المؤلفون: Greenbaum, Carla J, Serti, Elisavet, Lambert, Katharina, Weiner, Lia J, Kanaparthi, Sai, Lord, Sandra, Gitelman, Stephen E, Wilson, Darrell M, Gaglia, Jason L, Griffin, Kurt J, Russell, William E, Raskin, Philip, Moran, Antoinette, Willi, Steven M, Tsalikian, Eva, DiMeglio, Linda A, Herold, Kevan C, Moore, Wayne V, Goland, Robin, Harris, Mark, Craig, Maria E, Schatz, Desmond A, Baidal, David A, Rodriguez, Henry, Utzschneider, Kristina M, Nel, Hendrik J, Soppe, Carol L, Boyle, Karen D, Cerosaletti, Karen, Keyes-Elstein, Lynette, Long, S Alice, Thomas, Ranjeny, McNamara, James G, Buckner, Jane H, Sanda, Srinath

المصدر: JCI Insight. 6(21)

مصطلحات موضوعية: Diabetes, Clinical Research, Clinical Trials and Supportive Activities, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Metabolic and endocrine, Good Health and Well Being, Adolescent, B-Lymphocyte Subsets, Child, Diabetes Mellitus, Type 1, Double-Blind Method, Female, Humans, Male, Receptors, Interleukin-6, ITN058AI EXTEND Study Team, Beta cells, Endocrinology, Immunology, T cells

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7n41s2shTest

المؤلفون: Rigby, Mark R, Harris, Kristina M, Pinckney, Ashley, DiMeglio, Linda A, Rendell, Marc S, Felner, Eric I, Dostou, Jean M, Gitelman, Stephen E, Griffin, Kurt J, Tsalikian, Eva, Gottlieb, Peter A, Greenbaum, Carla J, Sherry, Nicole A, Moore, Wayne V, Monzavi, Roshanak, Willi, Steven M, Raskin, Philip, Keyes-Elstein, Lynette, Long, S Alice, Kanaparthi, Sai, Lim, Noha, Phippard, Deborah, Soppe, Carol L, Fitzgibbon, Margret L, McNamara, James, Nepom, Gerald T, Ehlers, Mario R

المصدر: Journal of Clinical Investigation. 125(8)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Immunology, Autoimmune Disease, Diabetes, Pediatric, Clinical Trials and Supportive Activities, Complementary and Integrative Health, Clinical Research, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Metabolic and endocrine, Adolescent, Adult, Alefacept, C-Peptide, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Child, Dermatologic Agents, Diabetes Mellitus, Type 1, Double-Blind Method, Female, Humans, Immunologic Memory, Male, Recombinant Fusion Proteins, Time Factors, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7tx265zjTest

المؤلفون: Greenbaum, Carla J., Serti, Elisavet, Lambert, Katharina, Weiner, Lia J., Kanaparthi, Sai, Lord, Sandra, Gitelman, Stephen E., Wilson, Darrell M., Gaglia, Jason L., Griffin, Kurt J., Russell, William E., Raskin, Philip, Moran, Antoinette, Willi, Steven M., Tsalikian, Eva, DiMeglio, Linda A., Herold, Kevan C., Moore, Wayne V., Goland, Robin, Harris, Mark, Craig, Maria E., Schatz, Desmond A., Baidal, David A., Rodriguez, Henry, Utzschneider, Kristina M., Nel, Hendrik J., Soppe, Carol L., Boyle, Karen D., Cerosaletti, Karen, Keyes-Elstein, Lynette, Long, S. Alice, Thomas, Ranjeny, McNamara, James G., Buckner, Jane H., Sanda, Srinath, ITN058AI EXTEND Study Team

المساهمون: Pediatrics, School of Medicine

المصدر: Publisher

مصطلحات موضوعية: IL-6 receptor (IL-6R) signaling, Type 1 diabetes pathogenesis, Tocilizumab

وصف الملف: application/pdf

العلاقة: JCI Insight; Greenbaum CJ, Serti E, Lambert K, et al. IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight. 2021;6(21). doi:10.1172/jci.insight.150074; https://hdl.handle.net/1805/40166Test

الإتاحة: https://doi.org/10.1172/jci.insight.150074Test
https://hdl.handle.net/1805/40166Test

المؤلفون: Pinckney, Ashley, Rigby, Mark R., Keyes-Elstein, Lynette, Soppe, Carol L., Nepom, Gerald T., Ehlers, Mario R.

المصدر: Clinical Therapeutics ; volume 38, issue 6, page 1327-1339 ; ISSN 0149-2918

مصطلحات موضوعية: Pharmacology (medical), Pharmacology

الإتاحة: https://doi.org/10.1016/j.clinthera.2016.04.032Test
https://api.elsevier.com/content/article/PII:S0149291816302661?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0149291816302661?httpAccept=text/plainTest

المؤلفون: Rigby, Mark R., Harris, Kristina M., Pinckney, Ashley, DiMeglio, Linda A., Rendell, Marc S., Felner, Eric I., Dostou, Jean M., Gitelman, Stephen E., Griffin, Kurt J., Tsalikian, Eva, Gottlieb, Peter A., Greenbaum, Carla J., Sherry, Nicole A., Moore, Wayne V., Monzavi, Roshanak, Willi, Steven M., Raskin, Philip, Keyes-Elstein, Lynette, Long, S. Alice, Kanaparthi, Sai, Lim, Noha, Phippard, Deborah, Soppe, Carol L., Fitzgibbon, Margret L., McNamara, James, Nepom, Gerald T., Ehlers, Mario R.

المساهمون: Department of Pediatrics, IU School of Medicine

المصدر: PMC

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, immunology, metabolism, CD8-Positive T-Lymphocytes, Dermatologic Agents, administration & dosage, Diabetes Mellitus, Type 1, blood, drug therapy, Immunologic Memory, drug effects, Recombinant Fusion Proteins

وصف الملف: application/pdf

العلاقة: The Journal of Clinical Investigation; Rigby, M. R., Harris, K. M., Pinckney, A., DiMeglio, L. A., Rendell, M. S., Felner, E. I., … the Immune Tolerance Network (ITN) T1DAL Study Group. (2015). Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. The Journal of Clinical Investigation, 125(8), 3285–3296. http://doi.org/10.1172/JCI81722Test; https://hdl.handle.net/1805/11401Test

الإتاحة: https://doi.org/10.1172/JCI81722Test
https://hdl.handle.net/1805/11401Test

المؤلفون: Rigby, Mark R., Harris, Kristina M., Pinckney, Ashley, Dimeglio, Linda A., Rendell, Marc S., Felner, Eric I., Dostou, Jean M., Gitelman, Stephen E., Tsalikian, Eva, Griffin, Kurt J., Gottlieb, Peter A., Greenbaum, Carla J., Sherry, Nicole A., Moore, Wayne V., Monzavi, Roshanak, Willi, Steven M., Raskin, Philip, Keyes-Elstein, Lynette, Long, Sarah A., Kanaparthi, Sai, Lim, Noha, Phippard, Deborah, Soppe, Carol L., Fitzgibbon, Margret L., Mcnamara, James, Nepom, Gerald T., Ehlers, Mario R.

المصدر: Nederlands Tijdschrift voor Diabetologie ; volume 13, issue 3, page 56-57 ; ISSN 1567-2743 1876-6242

الإتاحة: https://doi.org/10.1007/s12467-015-0023-zTest