المؤلفون: Li, Hanqin, Busquets, Oriol, Verma, Yogendra, Syed, Khaja Mohieddin, Kutnowski, Nitzan, Pangilinan, Gabriella R, Gilbert, Luke A, Bateup, Helen S, Rio, Donald C, Hockemeyer, Dirk, Soldner, Frank

مصطلحات موضوعية: Regenerative Medicine, Stem Cell Research - Induced Pluripotent Stem Cell, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research - Embryonic - Human, Biotechnology, Stem Cell Research, Generic health relevance, Humans, RNA, Guide, Kinetoplastida, Gene Editing, Pluripotent Stem Cells, Deoxyribonuclease I, RNA, Messenger, RNA-Directed DNA Polymerase, Ribonucleoproteins, CRISPR-Cas Systems, hPSCs, prime editing, disease models, parkinson's disease, genome engineering, Human, genetics, genomics, human, regenerative medicine, stem cells, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9446m3x7Test

المؤلفون: Oh, Chang-Ki, Sultan, Abdullah, Platzer, Joseph, Dolatabadi, Nima, Soldner, Frank, McClatchy, Daniel B, Diedrich, Jolene K, Yates, John R, Ambasudhan, Rajesh, Nakamura, Tomohiro, Jaenisch, Rudolf, Lipton, Stuart A

المصدر: Cell Reports. 21(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell, Aging, Parkinson's Disease, Stem Cell Research, Neurosciences, Neurodegenerative, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Humans, Induced Pluripotent Stem Cells, Mice, Mitochondria, Mitophagy, Mutation, Neurons, Parkinson Disease, Protein Kinases, Ubiquitin-Protein Ligases, PARK2, PARK6, PINK1, Parkin, Parkinson’s disease, S-nitrosylation, mitophagy, Medical Physiology, Biological sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3cq4006fTest

المؤلفون: Brennand, Kristen J, Marchetto, M Carol, Benvenisty, Nissim, Brüstle, Oliver, Ebert, Allison, Belmonte, Juan Carlos Izpisua, Kaykas, Ajamete, Lancaster, Madeline A, Livesey, Frederick J, McConnell, Michael J, McKay, Ronald D, Morrow, Eric M, Muotri, Alysson R, Panchision, David M, Rubin, Lee L, Sawa, Akira, Soldner, Frank, Song, Hongjun, Studer, Lorenz, Temple, Sally, Vaccarino, Flora M, Wu, Jun, Vanderhaeghen, Pierre, Gage, Fred H, Jaenisch, Rudolf

المصدر: Stem Cell Reports. 5(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Bioengineering, Neurosciences, Clinical Research, Stem Cell Research, Neurological, Brain, Brain Diseases, Drug Discovery, Humans, Induced Pluripotent Stem Cells, Mosaicism, Neurogenesis, Precision Medicine, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9f88h9dwTest

المؤلفون: Soldner, Frank, Jaenisch, Rudolf

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: Springer

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1007/978-3-319-60192-2_1Test; Genome Editing in Neurosciences; https://hdl.handle.net/1721.1/126406Test

الإتاحة: https://doi.org/10.1007/978-3-319-60192-2_1Test
https://hdl.handle.net/1721.1/126406Test

المؤلفون: Song, Yuelin, van den Berg, Patrick R., Markoulaki, Styliani, Soldner, Frank, Dall’Agnese, Alessandra, Henninger, Jonathan E., Drotar, Jesse, Rosenau, Nicholas, Cohen, Malkiel A., Young, Richard A., Semrau, Stefan, Stelzer, Yonatan, Jaenisch, Rudolf

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/j.molcel.2019.06.045Test; Molecular Cell; https://hdl.handle.net/1721.1/127657Test; Song, Yuelin et al. "Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs." Molecular Cell 75, 5 (September 2019): P905-920.e6 © 2019 Elsevier Inc

الإتاحة: https://doi.org/10.1016/j.molcel.2019.06.045Test
https://hdl.handle.net/1721.1/127657Test

المؤلفون: Fanning, Saranna, Haque, Aftabul, Imberdis, Thibaut, Baru, Valeriya, Barrasa, M. Inmaculada, Nuber, Silke, Termine, Daniel, Ramalingam, Nagendran, Ho, Gary P.H., Noble, Tallie, Sandoe, Jackson, Lou, Yali, Landgraf, Dirk, Freyzon, Yelena, Newby, Gregory, Soldner, Frank, Terry-Kantor, Elizabeth, Kim, Tae-Eun, Hofbauer, Harald F., Becuwe, Michel, Jaenisch, Rudolf, Pincus, David, Clish, Clary B., Walther, Tobias C., Farese, Robert V., Srinivasan, Supriya, Welte, Michael A., Kohlwein, Sepp D., Dettmer, Ulf, Lindquist, Susan, Selkoe, Dennis

المساهمون: Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology. Department of Biology, Broad Institute of MIT and Harvard

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/j.molcel.2018.11.028Test; Molecular Cell; https://hdl.handle.net/1721.1/125128Test; Fanning, Saranna et al. "Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment." Molecular Cell 73, 5 (March 2019): 1001-1014 © 2018 Elsevier Inc.

الإتاحة: https://doi.org/10.1016/j.molcel.2018.11.028Test
https://hdl.handle.net/1721.1/125128Test

المؤلفون: Soldner, Frank, Jaenisch, Rudolf

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/j.cell.2018.09.010Test; Cell; https://hdl.handle.net/1721.1/125973Test; Soldner, Frank and Rudolf Jaenisch. "Stem Cells, Genome Editing, and the Path to Translational Medicine." Cell 175, 3 (October 2018): P615-632 © 2018 Elsevier Inc

الإتاحة: https://doi.org/10.1016/j.cell.2018.09.010Test
https://hdl.handle.net/1721.1/125973Test

المؤلفون: Song, Yuelin, van den Berg, Patrick R., Markoulaki, Styliani, Soldner, Frank, Dall’Agnese, Alessandra, Henninger, Jonathan E., Drotar, Jesse, Rosenau, Nicholas, Cohen, Malkiel A., Young, Richard A., Semrau, Stefan, Stelzer, Yonatan, Jaenisch, Rudolf

المساهمون: HFSP long-term fellowship, ISF, Louis and Ida Rich Career Development Chair, NIH

المصدر: Molecular Cell ; volume 75, issue 5, page 905-920.e6 ; ISSN 1097-2765

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1016/j.molcel.2019.06.045Test
https://api.elsevier.com/content/article/PII:S1097276519305027?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1097276519305027?httpAccept=text/plainTest

المؤلفون: Fanning, Saranna, Haque, Aftabul, Imberdis, Thibaut, Baru, Valeriya, Barrasa, M. Inmaculada, Nuber, Silke, Termine, Daniel, Ramalingam, Nagendran, Ho, Gary P.H., Noble, Tallie, Sandoe, Jackson, Lou, Yali, Landgraf, Dirk, Freyzon, Yelena, Newby, Gregory, Soldner, Frank, Terry-Kantor, Elizabeth, Kim, Tae-Eun, Hofbauer, Harald F., Becuwe, Michel, Jaenisch, Rudolf, Pincus, David, Clish, Clary B., Walther, Tobias C., Farese, Robert V., Srinivasan, Supriya, Welte, Michael A., Kohlwein, Sepp D., Dettmer, Ulf, Lindquist, Susan, Selkoe, Dennis

المساهمون: Austrian Science Fund FWF, DK Molecular Enzymology Project, NAWI Graz, JPB Foundation, HHMI, Jane Coffin Childs Memorial Fund, NIH

المصدر: Molecular Cell ; volume 73, issue 5, page 1001-1014.e8 ; ISSN 1097-2765

الإتاحة: https://doi.org/10.1016/j.molcel.2018.11.028Test
https://api.elsevier.com/content/article/PII:S1097276518309985?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1097276518309985?httpAccept=text/plainTest