المؤلفون: Tracy, Tara E, Madero-Pérez, Jesus, Swaney, Danielle L, Chang, Timothy S, Moritz, Michelle, Konrad, Csaba, Ward, Michael E, Stevenson, Erica, Hüttenhain, Ruth, Kauwe, Grant, Mercedes, Maria, Sweetland-Martin, Lauren, Chen, Xu, Mok, Sue-Ann, Wong, Man Ying, Telpoukhovskaia, Maria, Min, Sang-Won, Wang, Chao, Sohn, Peter Dongmin, Martin, Jordie, Zhou, Yungui, Luo, Wenjie, Trojanowski, John Q, Lee, Virginia MY, Gong, Shiaoching, Manfredi, Giovanni, Coppola, Giovanni, Krogan, Nevan J, Geschwind, Daniel H, Gan, Li

المصدر: Cell. 185(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Alzheimer's Disease Related Dementias (ADRD), Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Dementia, Aging, Frontotemporal Dementia (FTD), Stem Cell Research - Induced Pluripotent Stem Cell, Stem Cell Research, Acquired Cognitive Impairment, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Alzheimer's Disease, Neurosciences, Aetiology, 2.1 Biological and endogenous factors, Neurological, Alzheimer Disease, Amino Acids, Biotinylation, Brain, Cell Nucleus, Disease Progression, Energy Metabolism, Frontotemporal Dementia, Humans, Induced Pluripotent Stem Cells, Mitochondria, Mutant Proteins, Mutation, Nerve Degeneration, Neurons, Protein Binding, Protein Domains, Protein Interaction Maps, Proteomics, Severity of Illness Index, Subcellular Fractions, Synapses, Tauopathies, tau Proteins, APEX, Tau, Tau secretion, affinity purification mass spectrometry, interactome, mitochondria, neurodegeneration, protein-protein interaction, synapse, tauopathies, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9tw4v44tTest

المؤلفون: Caballero, Benjamin, Bourdenx, Mathieu, Luengo, Enrique, Diaz, Antonio, Sohn, Peter Dongmin, Chen, Xu, Wang, Chao, Juste, Yves R, Wegmann, Susanne, Patel, Bindi, Young, Zapporah T, Kuo, Szu Yu, Rodriguez-Navarro, Jose Antonio, Shao, Hao, Lopez, Manuela G, Karch, Celeste M, Goate, Alison M, Gestwicki, Jason E, Hyman, Bradley T, Gan, Li, Cuervo, Ana Maria

المصدر: Nature communications. 12(1)

مصطلحات موضوعية: Brain, Neurons, Animals, Mice, Inbred C57BL, Humans, Mice, Tauopathies, tau Proteins, Acetylation, Female, Male, Chaperone-Mediated Autophagy, Alzheimer's Disease, Frontotemporal Dementia (FTD), Alzheimer's Disease Related Dementias (ADRD), Dementia, Aging, Neurosciences, Acquired Cognitive Impairment, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, 2.1 Biological and endogenous factors, Neurological

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/08b6k9xcTest

المؤلفون: Sohn, Peter Dongmin, Huang, Cindy Tzu-Ling, Yan, Rui, Fan, Li, Tracy, Tara E, Camargo, Carolina M, Montgomery, Kelly M, Arhar, Taylor, Mok, Sue-Ann, Freilich, Rebecca, Baik, Justin, He, Manni, Gong, Shiaoching, Roberson, Erik D, Karch, Celeste M, Gestwicki, Jason E, Xu, Ke, Kosik, Kenneth S, Gan, Li

المصدر: Neuron. 104(3)

مصطلحات موضوعية: Neurons, Extracellular Space, Cytoskeleton, Humans, Microtubule-Associated Proteins, tau Proteins, Homeostasis, Neuronal Plasticity, Mutation, Electrophysiological Phenomena, Induced Pluripotent Stem Cells, Frontotemporal Dementia, Protein Aggregation, Pathological, Axon Initial Segment, EB3, FTD, axon initial segment, cytoskeleton, homeostasis, neuronal activity, tau, Stem Cell Research - Induced Pluripotent Stem Cell, Frontotemporal Dementia (FTD), Stem Cell Research - Induced Pluripotent Stem Cell - Human, Brain Disorders, Alzheimer's Disease Related Dementias (ADRD), Rare Diseases, Alzheimer's Disease, Neurosciences, Acquired Cognitive Impairment, Aging, Neurodegenerative, Dementia, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Stem Cell Research, Genetics, 2.1 Biological and endogenous factors, Aetiology, Neurological, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4z5708t7Test

المؤلفون: Karch, Celeste M, Kao, Aimee W, Karydas, Anna, Onanuga, Khadijah, Martinez, Rita, Argouarch, Andrea, Wang, Chao, Huang, Cindy, Sohn, Peter Dongmin, Bowles, Kathryn R, Spina, Salvatore, Silva, M Catarina, Marsh, Jacob A, Hsu, Simon, Pugh, Derian A, Ghoshal, Nupur, Norton, Joanne, Huang, Yadong, Lee, Suzee E, Seeley, William W, Theofilas, Panagiotis, Grinberg, Lea T, Moreno, Fermin, McIlroy, Kathryn, Boeve, Bradley F, Cairns, Nigel J, Crary, John F, Haggarty, Stephen J, Ichida, Justin K, Kosik, Kenneth S, Miller, Bruce L, Gan, Li, Goate, Alison M, Temple, Sally, Alquezar, Carolina, Bowles, Kathryn, Butler, David, Hernandez, Israel, Hennes, Valerie, Kampmann, Martin

المصدر: Stem Cell Reports. 13(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Regenerative Medicine, Stem Cell Research - Induced Pluripotent Stem Cell, Alzheimer's Disease Related Dementias (ADRD), Dementia, Aging, Acquired Cognitive Impairment, Neurodegenerative, Stem Cell Research, Neurosciences, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Alzheimer's Disease, Frontotemporal Dementia (FTD), Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Pick's Disease, Genetics, Orphan Drug, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Neurological, Cell Line, Fibroblasts, Gene Editing, Humans, Induced Pluripotent Stem Cells, Mutation, Neural Stem Cells, Neurogenesis, Neurons, Tauopathies, tau Proteins, Tau Consortium Stem Cell Group, CRISPR/Cas9, MAPT, corticobasal degeneration, fibroblasts, frontotemporal dementia, induced pluripotent stem cells, neural progenitor cells, progressive supranuclear palsy, tau, tauopathy, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3qq1v8t1Test
https://escholarship.org/content/qt3qq1v8t1/qt3qq1v8t1.pdfTest

المؤلفون: Min, Sang-Won, Sohn, Peter Dongmin, Li, Yaqiao, Devidze, Nino, Johnson, Jeffrey R, Krogan, Nevan J, Masliah, Eliezer, Mok, Sue-Ann, Gestwicki, Jason E, Gan, Li

المصدر: Journal of Neuroscience. 38(15)

مصطلحات موضوعية: Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aging, Alzheimer's Disease, Brain Disorders, Neurosciences, Acquired Cognitive Impairment, Neurodegenerative, Frontotemporal Dementia (FTD), Dementia, Aetiology, 2.1 Biological and endogenous factors, Neurological, Acetylation, Animals, Female, HEK293 Cells, Hippocampus, Humans, Male, Maze Learning, Mice, Sirtuin 1, Synaptic Transmission, Tauopathies, tau Proteins, acetylation, dementia, SIRT1, tau, tau spread, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3mc408tdTest

المؤلفون: Wang, Chao, Ward, Michael E, Chen, Robert, Liu, Kai, Tracy, Tara E, Chen, Xu, Xie, Min, Sohn, Peter Dongmin, Ludwig, Connor, Meyer-Franke, Anke, Karch, Celeste M, Ding, Sheng, Gan, Li

المصدر: Stem cell reports. 9(4)

مصطلحات موضوعية: Neurons, Cells, Cultured, Cell Line, Humans, Glutamine, tau Proteins, Drug Evaluation, Preclinical, Cell Differentiation, Cell Survival, Gene Expression, Gene Expression Regulation, Membrane Potentials, Gene Order, Genetic Vectors, Drug Discovery, Induced Pluripotent Stem Cells, High-Throughput Screening Assays, Alzheimer’s disease, Tau-lowering, adrenergic receptor, frontotemporal dementia, high-content screening, human induced pluripotent stem cells, human neurons, neurodegeneration, neurogenin 2, tau, Cells, Cultured, Drug Evaluation, Preclinical, Biochemistry and Cell Biology, Clinical Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1km1c703Test

المؤلفون: Sohn, Peter Dongmin, Tracy, Tara E, Son, Hye-In, Zhou, Yungui, Leite, Renata EP, Miller, Bruce L, Seeley, William W, Grinberg, Lea T, Gan, Li

المصدر: Molecular Neurodegeneration. 11(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Aging, Alzheimer's Disease, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Dementia, Neurosciences, Neurodegenerative, Acquired Cognitive Impairment, 2.1 Biological and endogenous factors, Underpinning research, Aetiology, 1.1 Normal biological development and functioning, Neurological, Acetylation, Aged, Aged, 80 and over, Alzheimer Disease, Animals, Axon Initial Segment, Blotting, Western, Cell Polarity, Cytoskeleton, Disease Models, Animal, Female, Humans, Immunohistochemistry, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Confocal, Neurons, Rats, tau Proteins, Alzheimer's disease, Neuronal polarity, Tau acetylation, Axon initial segment, Neuronal cytoskeleton, Alzheimer’s disease, Genetics, Clinical Sciences, Neurology & Neurosurgery, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/17z8282zTest

المؤلفون: Cho, Seo-Hyun, Chen, Jason A, Sayed, Faten, Ward, Michael E, Gao, Fuying, Nguyen, Thi A, Krabbe, Grietje, Sohn, Peter Dongmin, Lo, Iris, Minami, Sakura, Devidze, Nino, Zhou, Yungui, Coppola, Giovanni, Gan, Li

المصدر: Journal of Neuroscience. 35(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Aging, Neurodegenerative, Brain Disorders, Acquired Cognitive Impairment, Dementia, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Genetics, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Neurological, Animals, Case-Control Studies, Cognition, DNA Methylation, Epigenesis, Genetic, Humans, Interleukin-1beta, Mice, Microglia, Sirtuin 1, Tauopathies, Up-Regulation, epigenetic, innate immunity, interleukin, memory deficits, neuroinflammation, NF-kappa B, NF-κ B, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4w97s39wTest

المؤلفون: Grinberg, Lea Tenenholz, Wang, Xuehua, Wang, Chao, Sohn, Peter Dongmin, Theofilas, Panos, Sidhu, Manu, Arevalo, John Benjamin, Heinsen, Helmut, Huang, Eric J, Rosen, Howard, Miller, Bruce L, Gan, Li, Seeley, William W

المصدر: Acta Neuropathologica. 125(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Neurodegenerative, Aging, Alzheimer's Disease, Acquired Cognitive Impairment, Dementia, Frontotemporal Dementia (FTD), Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), 2.1 Biological and endogenous factors, Aetiology, Acetylation, Aged, Aged, 80 and over, Brain, Diagnosis, Differential, Female, Humans, Immunohistochemistry, Male, Middle Aged, Neurofibrillary Tangles, Phosphorylation, Plaque, Amyloid, Protein Processing, Post-Translational, Tauopathies, tau Proteins, Tau, Pathology, Autopsy, Human, Clinical Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7570q4r5Test

المؤلفون: Zhan, Lihong, Fan, Li, Kodama, Lay, Sohn, Peter Dongmin, Wong, Man Ying, Mousa, Gergey Alzaem, Zhou, Yungui, Li, Yaqiao, Gan, Li

المساهمون: National Institutes of Health, National Institute of Aging

المصدر: eLife ; volume 9 ; ISSN 2050-084X

الإتاحة: https://doi.org/10.7554/elife.51796Test
https://cdn.elifesciences.org/articles/51796/elife-51796-v2.pdfTest
https://cdn.elifesciences.org/articles/51796/elife-51796-v2.xmlTest
https://elifesciences.org/articles/51796Test