دورية أكاديمية

Explainable Automated TI-RADS Evaluation of Thyroid Nodules

التفاصيل البيبلوغرافية
العنوان: Explainable Automated TI-RADS Evaluation of Thyroid Nodules
المؤلفون: Alisa Kunapinun, Dittapong Songsaeng, Sittaya Buathong, Matthew N. Dailey, Chadaporn Keatmanee, Mongkol Ekpanyapong
المصدر: Sensors, Vol 23, Iss 16, p 7289 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Chemical technology
مصطلحات موضوعية: thyroid nodule, TI-RADS, classification, deep learning, Grad-CAM, heatmap, Chemical technology, TP1-1185
الوصف: A thyroid nodule, a common abnormal growth within the thyroid gland, is often identified through ultrasound imaging of the neck. These growths may be solid- or fluid-filled, and their treatment is influenced by factors such as size and location. The Thyroid Imaging Reporting and Data System (TI-RADS) is a classification method that categorizes thyroid nodules into risk levels based on features such as size, echogenicity, margin, shape, and calcification. It guides clinicians in deciding whether a biopsy or other further evaluation is needed. Machine learning (ML) can complement TI-RADS classification, thereby improving the detection of malignant tumors. When combined with expert rules (TI-RADS) and explanations, ML models may uncover elements that TI-RADS misses, especially when TI-RADS training data are scarce. In this paper, we present an automated system for classifying thyroid nodules according to TI-RADS and assessing malignancy effectively. We use ResNet-101 and DenseNet-201 models to classify thyroid nodules according to TI-RADS and malignancy. By analyzing the models’ last layer using the Grad-CAM algorithm, we demonstrate that these models can identify risk areas and detect nodule features relevant to the TI-RADS score. By integrating Grad-CAM results with feature probability calculations, we provide a precise heat map, visualizing specific features within the nodule and potentially assisting doctors in their assessments. Our experiments show that the utilization of ResNet-101 and DenseNet-201 models, in conjunction with Grad-CAM visualization analysis, improves TI-RADS classification accuracy by up to 10%. This enhancement, achieved through iterative analysis and re-training, underscores the potential of machine learning in advancing thyroid nodule diagnosis, offering a promising direction for further exploration and clinical application.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 23167289
1424-8220
العلاقة: https://www.mdpi.com/1424-8220/23/16/7289Test; https://doaj.org/toc/1424-8220Test
DOI: 10.3390/s23167289
الوصول الحر: https://doaj.org/article/e19a168cd0d340b89b05d7ffab9cd061Test
رقم الانضمام: edsdoj.19a168cd0d340b89b05d7ffab9cd061
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23167289
14248220
DOI:10.3390/s23167289