المؤلفون: Conor J. Bloxham, Simon R. Foster, Walter G. Thomas

المصدر: Frontiers in Physiology, Vol 11 (2020)

مصطلحات موضوعية: taste receptors, G protein-coupled receptors, cardiac physiology, signaling, polymorphisms, bitter ligands, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fphys.2020.00431/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/b4076aeda87d40e1a22d33e813cf6fa0Test

المؤلفون: Siyao Wang (1468693), Simon R. Foster (8810318), Julie Sanchez (6990179), Leo Corcilius (1883605), Mark Larance (2151373), Meritxell Canals (175821), Martin J. Stone (1335942), Richard J. Payne (401410)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, CCL 14, leukocyte migration, chemokine receptors, Chemokine CCL 14 Chemokines, CCR 1 binding affinity, nonsialylated forms, glycosylated variants, chemical ligation, peptide fragments, sialylated variants, sequential ligation reactions

العلاقة: https://figshare.com/articles/journal_contribution/Glycosylation_Regulates_N_Terminal_Proteolysis_and_Activity_of_the_Chemokine_CCL14/14600035Test

الإتاحة: https://doi.org/10.1021/acschembio.1c00006.s001Test

المؤلفون: Holly K. Voges, Simon R. Foster, Liam Reynolds, Benjamin L. Parker, Lynn Devilée, Gregory A. Quaife-Ryan, Patrick R.J. Fortuna, Ellen Mathieson, Rebecca Fitzsimmons, Mary Lor, Christopher Batho, Janice Reid, Mark Pocock, Clayton E. Friedman, Dalia Mizikovsky, Mathias Francois, Nathan J. Palpant, Elise J. Needham, Marina Peralta, Gonzalo del Monte-Nieto, Lynelle K. Jones, Ian M. Smyth, Neda R. Mehdiabadi, Francesca Bolk, Vaibhao Janbandhu, Ernestene Yao, Richard P. Harvey, James J.H. Chong, David A. Elliott, Edouard G. Stanley, Sophie Wiszniak, Quenten Schwarz, David E. James, Richard J. Mills, Enzo R. Porrello, James E. Hudson

المساهمون: Voges, Holly K, Foster, Simon R, Reynolds, Liam, Parker, Benjamin L, Wiszniak, Sophie, Schwarz, Quenten, Hudson, James E

مصطلحات موضوعية: cardiac organoid, inflammation, extracellular matrix, endothelin-1, disease modeling, LAMA5, PDGF, General Biochemistry, Genetics and Molecular Biology, endothelial cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8998951ca54fee675a01326833731ecaTest
https://hdl.handle.net/11541.2/34444Test

المؤلفون: Richard J. Payne, Meritxell Canals, Martin J. Stone, Mark Larance, Julie Sanchez, Leo Corcilius, Siyao Wang, Simon R. Foster

المصدر: ACS Chemical Biology. 16:973-981

مصطلحات موضوعية: 0301 basic medicine, CCR1, Leukocyte migration, Chemokine, Glycosylation, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Chemokine receptor, Protein Domains, Humans, Amino Acid Sequence, CCL14, biology, 010405 organic chemistry, Chemistry, General Medicine, Ligand (biochemistry), Native chemical ligation, 0104 chemical sciences, Cell biology, 030104 developmental biology, Chemokines, CC, Proteolysis, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39029be6bfe67b55fdf5711513491483Test
https://doi.org/10.1021/acschembio.1c00006Test

المؤلفون: Lisa Pallareti, Tine F. Rath, Boris Trapkov, Tsonko Tsonkov, Anders Thorup Nielsen, Kasper Harpsøe, Patrick R. Gentry, Hans Bräuner-Osborne, David E. Gloriam, Simon R. Foster

المصدر: Pallareti, L, Rath, T F, Trapkov, B, Tsonkov, T, Nielsen, A T, Harpsøe, K, Gentry, P R, Bräuner-Osborne, H, Gloriam, D E & Foster, S R 2023, ' Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139 ', European Journal of Pharmacology, vol. 943, 175553 . https://doi.org/10.1016/j.ejphar.2023.175553Test

مصطلحات موضوعية: Pharmacology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df85ff1cb32d698c2e455b397ca2dea3Test
https://doi.org/10.1016/j.ejphar.2023.175553Test

المؤلفون: Ram Prasad Bhusal, Pramod Aryal, Shankar Raj Devkota, Rina Pokhrel, Menachem J. Gunzburg, Simon R. Foster, Herman D. Lim, Richard J. Payne, Matthew C. J. Wilce, Martin J. Stone

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(9)

مصطلحات موضوعية: Inflammation, Multidisciplinary, Ticks, Protein Conformation, Animals, Receptors, Chemokine, Chemokines, Protein Engineering, Arthropod Proteins, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2454c667f2d1c3b56383b01c9509197aTest
https://pubmed.ncbi.nlm.nih.gov/35217625Test

المؤلفون: Michelle Cielesh, Martin J. Stone, Mark Larance, Simon R. Foster, Sayeeda Tasneem Chowdhury, Joel P. Mackay, Charlotte Franck, Ram Prasad Bhusal, Richard J. Payne, Jason Johansen-Leete

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: 0301 basic medicine, Tyrosine sulfation, Chemokine, Arthropod Proteins, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Sulfation, Animals, Humans, Tyrosine, Saliva, Acari, Multidisciplinary, biology, Sulfates, Chemistry, Native chemical ligation, Semisynthesis, Cell biology, HEK293 Cells, 030104 developmental biology, Chemokine binding, Physical Sciences, biology.protein, Chemokines, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0180562ed68d8e3c4263d792d27efe4Test
https://doi.org/10.1073/pnas.2000605117Test

المؤلفون: Martin J. Stone, Anup Shah, Oded Kleifeld, Ralf B. Schittenhelm, Meritxell Canals, Cheng Huang, Simon R. Foster

المصدر: J Biol Chem

مصطلحات موضوعية: Proteomics, 0301 basic medicine, CCR2, Chemokine, Cell signaling, Receptors, CCR2, Biochemistry, 03 medical and health sciences, Chemokine receptor, Humans, Phosphorylation, Molecular Biology, 030102 biochemistry & molecular biology, biology, Chemistry, Phosphoproteomics, Cell Biology, Phosphoproteins, Actin cytoskeleton, Cell biology, Gene Ontology, HEK293 Cells, 030104 developmental biology, biology.protein, Signal transduction, CC chemokine receptors, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505094ce6d8180f3c2d2c90451084238Test
https://doi.org/10.1074/jbc.ra119.012026Test

المؤلفون: Hans Bräuner-Osborne, Karen J. Gregory, Thor C. Møller, Line Vedel, Angela Arsova, Simon R. Foster, Jakob Lerche Hansen

المصدر: Mol Pharmacol
Molecular Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Indoles, Time Factors, Pyridines, Inositol Phosphates, Receptor, Metabotropic Glutamate 5, Allosteric regulation, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Allosteric Regulation, Animals, Humans, Mavoglurant, Phosphorylation, Receptor, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Molecular Structure, Metabotropic glutamate receptor 5, Kinase, Imidazoles, Glutamate receptor, Isoxazoles, Articles, Triazoles, In vitro, Rats, HEK293 Cells, 030104 developmental biology, Metabotropic receptor, chemistry, Molecular Medicine, Calcium, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e3a856e1919599f13a55388bfec28cTest
https://doi.org/10.1124/mol.119.119032Test

المؤلفون: Daniel J Ford, Martin J. Stone, Minglong Liu, Ram Prasad Bhusal, Seino A. K. Jongkees, Richard J. Payne, Jason Johansen-Leete, Simon R. Foster, Hiroaki Suga, Toby Passioura

المصدر: Journal of the American Chemical Society. 142:9141-9146

مصطلحات موضوعية: Chemokine CCL11, Chemokine, CCR3, 010402 general chemistry, CCL7, 01 natural sciences, Biochemistry, Catalysis, Colloid and Surface Chemistry, Drug Discovery, Humans, mRNA display, RNA, Messenger, CCL11, Molecular Structure, biology, Chemistry, General Chemistry, 0104 chemical sciences, 3. Good health, Cell biology, Chemokine binding, biology.protein, Peptides, CCL24, CC chemokine receptors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2acd49507c63ab60282b1e7f4aa829Test
https://doi.org/10.1021/jacs.0c03152Test