نتائج البحث - "Simon J. Larsen"

المصدر: Systems Medicine
Systems medicine (New Rochelle, N.Y.), 3(1), 8-21
Larsen, S J, Schmidt, H H H W & Baumbach, J 2020, ' De Novo and Supervised Endophenotyping Using Network-Guided Ensemble Learning ', Network and Systems Medicine, vol. 3, no. 1, pp. 8-21 . https://doi.org/10.1089/sysm.2019.0008Test

مصطلحات موضوعية: 0303 health sciences, Computer science, Computational biology, Omics, Precision medicine, Ensemble learning, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Identification (biology), Clinical phenotype, Gene, 030304 developmental biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316b3746195fd684d5e222c5fb76c101Test
https://doi.org/10.1089/sysm.2019.0008Test

5

DeepCLIP: Predicting the effect of mutations on protein-RNA binding with Deep Learning

المؤلفون: Thomas Koed Doktor, Ulrika S. S. Petersen, Gitte Hoffmann Bruun, Alexander Gulliver Bjoernholt Groenning, Brage S. Andresen, Jan Baumbach, Simon J. Larsen, Michael Birkerod Hansen, Anne-Mette Hartung, Lise Lolle Holm

المصدر: Grønning, A G B, Doktor, T K, Larsen, S J, Petersen, U S S, Holm, L L, Bruun, G H, Hansen, M B, Hartung, A-M, Baumbach, J & Andresen, B S 2020, ' DeepCLIP : predicting the effect of mutations on protein-RNA binding with deep learning ', Nucleic acids research, vol. 48, no. 13, pp. 7099-7118 . https://doi.org/10.1093/nar/gkaa530Test
Nucleic Acids Research

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9df55350b26200afc645327c5e9008Test

6

From single drug targets to synergistic network pharmacology in ischemic stroke

المؤلفون: Emre Guney, Mahmoud H. Elbatreek, Harald H.H.W. Schmidt, Jan Baumbach, Javier Egea, Simon J. Larsen, Vanessa Gómez-Rangel, Ana I. Casas, Pamela W. M. Kleikers, Manuela G. López, Ahmed A. Hassan

المساهمون: Pharmacology and Personalised Medicine, RS: FHML non-thematic output

المصدر: Casas, A I, Hassan, A A, Larsen, S J, Gomez-Rangel, V, Elbatreek, M, Kleikers, P W M, Guney, E, Egea, J, López, M G, Baumbach, J & Schmidt, H H H W 2019, ' From single drug targets to synergistic network pharmacology in ischemic stroke ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 14, pp. 7129-7136 . https://doi.org/10.1073/pnas.1820799116Test
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 116(14), 7129-7136. National Academy of Sciences
Proceedings of the National Academy of Sciences

مصطلحات موضوعية: 0301 basic medicine, Male, PREDICTION, Pyrazoles/pharmacology, Nitric Oxide Synthase Type II, Disease, Nitric Oxide Synthase Type I, OXYGEN, Brain Ischemia, Mice, 0302 clinical medicine, Cell Death/drug effects, Drug Discovery, Nitric Oxide Synthase Type II/genetics, Nitric Oxide Synthase/drug effects, BRAIN, Stroke, network analysis, media_common, Multidisciplinary, NADPH oxidase, biology, Cell Death, Drug discovery, NOX4, Drug Synergism, Biological Sciences, stroke, ddc, 3. Good health, Drug Combinations, NG-Nitroarginine Methyl Ester, PNAS Plus, Blood-Brain Barrier, NADPH Oxidase 4, SIMILARITY, Nitric Oxide Synthase Type III/genetics, Network analysis, Female, Stroke/drug therapy, Blood-Brain Barrier/metabolism, Drug, EXPRESSION, Nitric Oxide Synthase Type III, Pyridones, media_common.quotation_subject, NOS1, BIOLOGY, 03 medical and health sciences, HYDROGEN-PEROXIDE, In vivo, Reactive Oxygen Species/metabolism, medicine, network pharmacology, Animals, NG-Nitroarginine Methyl Ester/pharmacology, Pyridones/pharmacology, Pharmacology, NITRIC-OXIDE, business.industry, NADPH Oxidase 4/drug effects, Brain Ischemia/drug therapy, medicine.disease, OFF-TARGET, Disease Models, Animal, 030104 developmental biology, CELLS, biology.protein, Pyrazoles, Nitric Oxide Synthase Type I/genetics, Nitric Oxide Synthase, business, Reactive Oxygen Species, Neuroscience, 030217 neurology & neurosurgery, Network pharmacology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bd3be0432e66a4fc3c69b16682fec9Test
https://findresearcher.sdu.dk:8443/ws/files/151606865/From_single_drug_targets_to_synergistic_network_pharmacology_in_ischemic_stroke.pdfTest

7

Comprehensive Genomic Profiling of Androgen-Receptor-Negative Canine Prostate Cancer

المؤلفون: Silvia Regina Rogatto, Márcio de Carvalho, Rolando A R Villacis, Carlos Eduardo Fonseca-Alves, Renée Laufer-Amorim, Sandra Aparecida Drigo Linde, Fabio Albuquerque Marchi, Simon J. Larsen

المساهمون: Universidade Estadual Paulista (Unesp), University of Brasília-UnB, University of Southern Denmark, A.C. Camargo Cancer Center

المصدر: International Journal of Molecular Sciences
Laufer-Amorim, R, Fonseca-Alves, C, Villacis, R A R, Linde, S A D, Carvalho, M, Larsen, S J, Marchi, F A & Rogatto, S R 2019, ' Comprehensive Genomic Profiling of Androgen-Receptor-Negative Canine Prostate Cancer ', International Journal of Molecular Sciences, vol. 20, no. 7, 1555 . https://doi.org/10.3390/ijms20071555Test
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1555 (2019)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Male, Microarray, CDH1, lcsh:Chemistry, Prostate cancer, 0302 clinical medicine, Dog, Dog Diseases, lcsh:QH301-705.5, Spectroscopy, Comparative Genomic Hybridization, biology, proliferative inflammatory atrophy, Proto-Oncogene Proteins c-mdm2, General Medicine, Genomics, Copy number alteration, prostate cancer, Computer Science Applications, Gene Expression Regulation, Neoplastic, Receptors, Androgen, 030220 oncology & carcinogenesis, dog, microarray, copy number alteration, DNA Copy Number Variations, comparative oncology, In silico, Catalysis, Article, Genomic Instability, Inorganic Chemistry, 03 medical and health sciences, Dogs, medicine, Proliferative inflammatory atrophy, Animals, Physical and Theoretical Chemistry, Molecular Biology, Gene, Comparative oncology, Organic Chemistry, Prostatic Neoplasms, medicine.disease, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Genomic Profile, biology.protein, Cancer research, Tumor Suppressor Protein p53, Transcriptome, Comparative genomic hybridization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb185fc81adaf0219e1a3674729518a5Test
http://europepmc.org/articles/PMC6480132Test

8

The Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That Is Associated With Expression of Glypican-3

المؤلفون: Alessandra M. Norris, Jonas G. King, Rebecca E. Tweedell, Timothy Hamerly, Dingyin Tao, Alexander G B Grønning, Jan Baumbach, Simon J. Larsen, Henry Chun Hin Law, Rhoel R. Dinglasan, Tanisha M. Robinson, Elke S. Bergmann-Leitner

المصدر: Frontiers in Microbiology
Tweedell, R E, Tao, D, Hamerly, T, Robinson, T M, Larsen, S, Grønning, A G B, Norris, A M, King, J G, Law, H C H, Baumbach, J, Bergmann-Leitner, E S & Dinglasan, R R 2019, ' The Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That Is Associated With Expression of Glypican-3 ', Frontiers in Microbiology, vol. 10, no. FEB, 127 . https://doi.org/10.3389/fmicb.2019.00127Test
Frontiers in Microbiology, Vol 10 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf94a0a031e8aa07840fd266eb17e05Test
https://doi.org/10.3389/fmicb.2019.00127Test

9

Increased Levels of Genomic Instability and Mutations in Homologous Recombination Genes in Locally Advanced Rectal Carcinomas

المؤلفون: Luisa Matos do Canto, Simon J. Larsen, Bruna E. Catin Kupper, Maria Dirlei Ferreira de Souza Begnami, Cristóvam Scapulatempo-Neto, Annabeth Høgh Petersen, Mads M. Aagaard, Jan Baumbach, Samuel Aguiar, Silvia R. Rogatto

المصدر: Frontiers in Oncology
Do Canto, L M, Larsen, S J, Kupper, B E C, De Souza Begnami, M D F, Scapulatempo-Neto, C, Petersen, A H, Aagaard, M M, Baumbach, J, Aguiar, S & Rogatto, S R 2019, ' Increased levels of genomic instability and mutations in homologous recombination genes in locally advanced rectal carcinomas ', Frontiers in Oncology, vol. 9, 00395 . https://doi.org/10.3389/fonc.2019.00395Test
Frontiers in Oncology, Vol 9 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6859b8f7a381dd874cccb4e0c2d998Test
https://pubmed.ncbi.nlm.nih.gov/31192117Test

10

Genomic profiling in ovarian cancer retreated with platinum based chemotherapy presented homologous recombination deficiency and copy number imbalances of CCNE1 and RB1 genes

المؤلفون: Simon J. Larsen, Alexandre Andre Balieiro Anastacio da Costa, Carlos Stecca, Louise De Brot, Silvia Regina Rogatto, Jan Baumbach, Maria Isabel Achatz, Adriana Regina Gonçalves Ribeiro, Annabeth Høgh Petersen, Luisa Matos do Canto, Glauco Baiocchi, Mads M. Aagaard

المصدر: BMC Cancer
da Costa, A A B A, do Canto, L M, Larsen, S J, Ribeiro, A R G, Stecca, C E, Petersen, A H, Aagaard, M M, de Brot, L, Baumbach, J, Baiocchi, G, Achatz, M I & Rogatto, S R 2019, ' Genomic profiling in ovarian cancer retreated with platinum based chemotherapy presented homologous recombination deficiency and copy number imbalances of CCNE1 and RB1 genes ', BMC Cancer, vol. 19, no. 1, 422 . https://doi.org/10.1186/s12885-019-5622-4Test
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_treatment, DNA Mutational Analysis, Platinum Compounds, Gene mutation, Treatment response, 0302 clinical medicine, Surgical oncology, RB1 loss, Antineoplastic Combined Chemotherapy Protocols, Target-next generation sequencing, Homologous Recombination, Response rate (survey), Oncogene Proteins, Ovarian Neoplasms, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Progression-Free Survival, ddc, Retinoblastoma Binding Proteins, 030220 oncology & carcinogenesis, Child, Preschool, PARP inhibitor, Retreatment, Female, Brazil, Research Article, medicine.medical_specialty, DNA Copy Number Variations, Ubiquitin-Protein Ligases, lcsh:RC254-282, 03 medical and health sciences, Ovarian cancer, Internal medicine, Cyclin E, Genetics, medicine, Humans, Progression-free survival, CCNE1 gains, Aged, Retrospective Studies, Chemotherapy, business.industry, Retrospective cohort study, medicine.disease, Survival Analysis, 030104 developmental biology, Drug Resistance, Neoplasm, Copy number alterations, business, Homologous recombination deficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b577ced9081cc766c41127cd6f7534Test
https://mediatum.ub.tum.de/doc/1545092/document.pdfTest

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