المؤلفون: Bale, Tracy L, Baram, Tallie Z, Brown, Alan S, Goldstein, Jill M, Insel, Thomas R, McCarthy, Margaret M, Nemeroff, Charles B, Reyes, Teresa M, Simerly, Richard B, Susser, Ezra S, Nestler, Eric J

المصدر: Biological Psychiatry. 68(4)

مصطلحات موضوعية: Behavioral and Social Science, Schizophrenia, Neurosciences, Mental Health, Pediatric, Genetics, Obesity, Nutrition, Intellectual and Developmental Disabilities (IDD), Brain Disorders, Metabolic and endocrine, Mental health, Quality Education, Animals, Brain, Disease Models, Animal, Environment, Epigenesis, Genetic, Female, Fetal Development, Gene Expression Regulation, Developmental, Genetic Predisposition to Disease, Humans, Maternal Exposure, Mental Disorders, Sex Factors, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2hx9g9b6Test

المؤلفون: Forger, Nancy G., Rosen, Greta J., Waters, Elizabeth M., Jacob, Dena, Simerly, Richard B., De Vries, Geert J., McEwen, Bruce S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2004 Sep . 101(37), 13666-13671.

الوصول الحر: https://www.jstor.org/stable/3373368Test

المؤلفون: Williford, Kellie M., Taylor, Anne, Melchior, James R., Yoon, Hye Jean, Sale, Eryn, Negasi, Milen D., Adank, Danielle N., Brown, Jordan A., Bedenbaugh, Michelle N., Luchsinger, Joseph R., Centanni, Samuel W., Patel, Sachin, Calipari, Erin S., Simerly, Richard B., Winder, Danny G.

المساهمون: Howard Hughes Medical Institute, U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke, U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse

المصدر: Neuropsychopharmacology ; volume 48, issue 7, page 1031-1041 ; ISSN 0893-133X 1740-634X

مصطلحات موضوعية: Psychiatry and Mental health, Pharmacology

الإتاحة: https://doi.org/10.1038/s41386-023-01569-5Test
https://www.nature.com/articles/s41386-023-01569-5.pdfTest
https://www.nature.com/articles/s41386-023-01569-5Test

المؤلفون: MacKay, Harry, Scott, C. Anthony, Duryea, Jack D., Baker, Maria S., Laritsky, Eleonora, Elson, Amanda E., Garland, Theodore, Fiorotto, Marta L., Chen, Rui, Li, Yumei, Coarfa, Cristian, Simerly, Richard B., Waterland, Robert A.

المساهمون: United States Department of Agriculture | Agricultural Research Service

المصدر: Nature Communications ; volume 10, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-019-13339-3Test
https://www.nature.com/articles/s41467-019-13339-3.pdfTest
https://www.nature.com/articles/s41467-019-13339-3Test

المؤلفون: van der Klaauw, Agatha A, Croizier, Sophie, Mendes de Oliveira, Edson, Stadler, Lukas KJ, Park, Soyoung, Kong, Youxin, Banton, Matthew C, Tandon, Panna, Hendricks, Audrey E, Keogh, Julia M, Riley, Susanna E, Papadia, Sofia, Henning, Elana, Bounds, Rebecca, Bochukova, Elena G, Mistry, Vanisha, O'Rahilly, Stephen, Simerly, Richard B, INTERVAL, UK10K Consortium, Minchin, James EN, Barroso, Inês, Jones, E Yvonne, Bouret, Sebastien G, Farooqi, I Sadaf

مصطلحات موضوعية: AgRP, Neuropilins, Plexins, Pomc, Semaphorin 3s, hypothalamus, obesity, Adolescent, Adult, Animals, Body Weight, Cell Line, Child, Preschool, Disease Models, Animal, Eating, Energy Metabolism, Female, Genetic Variation, Homeostasis, Humans, Leptin, Male, Melanocortins, Mice, Inbred C57BL, Middle Aged, Nerve Tissue Proteins, Neurons

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/288526Test

الإتاحة: https://doi.org/10.17863/CAM.35811Test
https://www.repository.cam.ac.uk/handle/1810/288526Test

المؤلفون: van der Klaauw, Agatha A., Croizier, Sophie, Mendes de Oliveira, Edson, Stadler, Lukas K.J., Park, Soyoung, Kong, Youxin, Banton, Matthew C., Tandon, Panna, Hendricks, Audrey E., Keogh, Julia M., Riley, Susanna E., Papadia, Sofia, Henning, Elana, Bounds, Rebecca, Bochukova, Elena G., Mistry, Vanisha, O’Rahilly, Stephen, Simerly, Richard B., Minchin, James E.N., Barroso, Inês, Jones, E. Yvonne, Bouret, Sebastien G., Farooqi, I. Sadaf

المساهمون: Wellcome, Medical Research Council, National Institute of Health Research, Cambridge Biomedical Research Centre, Bernard Wolfe Health Neuroscience Endowment, Brazilian National Council for Scientific and Technological Development, University of Edinburgh, British Heart Foundation, Centre of Research Excellence, NIH, Cancer Research UK, UK MRC, NHS Blood and Transplant England, NIHR, NIHR BioResource, NIHR Cambridge Biomedical Research Centre, NIHR Blood and Transplant Research Unit in Donor Health and Genomics, BHF, NIHR Cambridge BRC

المصدر: Cell ; volume 176, issue 4, page 729-742.e18 ; ISSN 0092-8674

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.cell.2018.12.009Test
https://api.elsevier.com/content/article/PII:S0092867418316234?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0092867418316234?httpAccept=text/plainTest

المؤلفون: Herrick, Mary K., Favela, Kristin M., Simerly, Richard B., Abumrad, Naji N., Bingham, Nathan C.

المساهمون: National Institutes of Health

المصدر: Molecular Medicine ; volume 24, issue 1 ; ISSN 1076-1551 1528-3658

مصطلحات موضوعية: Genetics (clinical), Genetics, Molecular Biology, Molecular Medicine

الإتاحة: https://doi.org/10.1186/s10020-018-0057-yTest

المؤلفون: Bouret, Sebastien G., Draper, Shin J., Simerly, Richard B.

المصدر: Science, 2004 Apr 01. 304(5667), 108-110.

الوصول الحر: https://www.jstor.org/stable/3836622Test

المؤلفون: Brown, Jordan A., Petersen, Nicholas, Centanni, Samuel W., Jin, Allie Y., Yoon, Hye Jean, Cajigas, Stephanie A., Bedenbaugh, Michelle N., Luchsinger, Joseph R., Patel, Sachin, Calipari, Erin S., Simerly, Richard B., Winder, Danny G.

المصدر: Neuropsychopharmacology; July 2023, Vol. 48 Issue: 8 p1133-1143, 11p

المؤلفون: Bedenbaugh, Michelle N., Brener, Samantha C., Maldonado, Jose, Lippert, Rachel N., Sweeney, Patrick, Cone, Roger D., Simerly, Richard B.

مصطلحات موضوعية: clearing, lightsheet, M3R, melanocortin, RNAscope, sex differences, Ecology and Evolutionary Biology, Science

وصف الملف: application/pdf

العلاقة: Bedenbaugh, Michelle N.; Brener, Samantha C.; Maldonado, Jose; Lippert, Rachel N.; Sweeney, Patrick; Cone, Roger D.; Simerly, Richard B. (2022). "Organization of neural systems expressing melanocortin-3 receptors in the mouse brain: Evidence for sexual dimorphism." Journal of Comparative Neurology 530(16): 2835-2851.; https://hdl.handle.net/2027.42/174918Test; Journal of Comparative Neurology; Saha, S. ( 2005 ). Role of the central nucleus of the amygdala in the control of blood pressure: Descending pathways to medullary cardiovascular nuclei. Clinical and Experimental Pharmacology and Physiology, 32, 450 – 456.; Risold, P. Y., & Swanson, L. W. ( 1997 ). Connections of the rat lateral septal complex. Brain Research Reviews, 24, 115 – 195.; Risold, P. Y., Thompson, R. H., & Swanson, L. W. ( 1997 ). The structural organization of connections between hypothalamus and cerebral. Brain Research Reviews, 24, 197 – 254.; Roselli-Rehfuss, L., Mountjoy, K. G., Robbins, L. S., Mortrud, M. T., Low, M. J., Tatro, J. B., Entwistle, M. L., Simerly, R. B., & Cone, R. D. ( 1993 ). Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proceedings of the National Academy of Sciences, 90, 8856 – 8860.; Saper, C. B. ( 2000 ). Hypothalamic connections with the cerebral cortex. Progress in Brain Research, 126, 39 – 48.; Saper, C. B., & Loewy, A. D. ( 1980 ). Efferent connections of the parabrachial nucleus in the rat. Brain Research, 197, 291 – 317.; Shanmugarajah, L., Dunigan, A. I., Frantz, K. J., & Roseberry, A. G. ( 2017 ). Altered sucrose self-administration following injection of melanocortin receptor agonists and antagonists into the ventral tegmental area. Psychopharmacology, 234, 1683 – 1692.; Simerly, R. B. ( 1998 ). Organization and regulation of sexually dimorphic neuroendocrine pathways. Behavioural Brain Research, 92, 195 – 203.; Simerly, R. B. ( 2002 ). Wired for reproduction: Organization and development of sexually dimorphic circuits in the mammalian forebrain. Annual Review of Neuroscience, 25, 507 – 536.; Simerly, R. B. ( 2005 ). Wired on hormones: Endocrine regulation of hypothalamic development. Current Opinion in Neurobiology, 15, 81 – 85.; Simerly, R. B. ( 2015 ). The rat nervous system ( 4 th ed.). Elsevier.; Simerly, R. B., Swanson, L. W., Chang, C., & Muramatsu, M. ( 1990 ). Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study. Journal of Comparative Neurology, 294, 76 – 95.; Simerly, R. B., Zee, M. C., Pendleton, J. W., Lubahn, D. B., & Korach, K. S. ( 1997 ). Estrogen receptor-dependent sexual differentiation of dopaminergic neurons in the preoptic region of the mouse. Proceedings of the National Academy of Sciences, 94, 14077 – 14082.; Simonds, S. E., Pryor, J. T., Ravussin, E., Greenway, F. L., Dileone, R., Allen, A. M., Bassi, J., Elmquist, J. K., Keogh, J. M., Henning, E., Myers, M. G., Licinio, J., Brown, R. D., Enriori, P. J., O’Rahilly, S., Sternson, S. M., Grove, K. L., Spanswick, D. C., Farooqi, I. S., & Cowley, M. A. ( 2014 ). Leptin mediates the increase in blood pressure associated with obesity. Cell, 159, 1404 – 1416.; Sutton, A. K., Goforth, P. B., Gonzalez, I. E., Dell’Orco, J., Pei, H., Myers, M. G., & Olson, D. P. ( 2021 ). Melanocortin 3 receptor-expressing neurons in the ventromedial hypothalamus promote glucose disposal. Proceedings of the National Academy of Sciences, 118, e2103090118.; Sutton, G. M., Perez-Tilve, D., Nogueiras, R., Fang, J., Kim, J. K., Cone, R. D., Gimble, J. M., Tschöp, M. H., & Butler, A. A. ( 2008 ). The melanocortin-3 receptor is required for entrainment to meal intake. Journal of Neuroscience, 28, 12946 – 12955.; Sutton, G. M., Trevaskis, J. L., Hulver, M. W., McMillan, R. P., Markward, N. J., Babin, M. J., Meyer, E. A., & Butler, A. A. ( 2006 ). Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors. Endocrinology, 147, 2183 – 2196.; Swaney, J., Kamentsky, L., Evans, N. B., Xie, K., Park, Y. - G., Drummond, G., Yun, D. H., & Chung, K. ( 2019 ). Scalable image processing techniques for quantitative analysis of volumetric biological images from light-sheet microscopy. https://doi.org/10.1101/576595Test; Swanson, L. W., & Cowan, W. ( 1975 ). Hippocampo-hypothalamic connections: Origin in subicular cortex, not ammon’s horn. Science, 189, 303 – 304.; Swanson, L. W. ( 2000 ). Cerebral hemisphere regulation of motivated behavior. Brain Research, 886, 113 – 164.; Swanson, L. W., & Cowan, W. M. ( 1979 ). The connections of the septal region in the rat. Journal of Comparative Neurology, 186, 621 – 655.; Swanson, L. W., & Petrovich, G. D. ( 1998 ). What is the amygdala? Trends in Neuroscience (Tins), 21, 323 – 331.; Sweeney, P., Bedenbaugh, M. N., Maldonado, J., Pan, P., Fowler, K., Williams, S. Y., Gimenez, L. E., Ghamari-Langroudi, M., Downing, G., Gui, Y., Hadley, C. K., Joy, S. T., Mapp, A. K., Simerly, R. B., & Cone, R. D. ( 2021 ). The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia. Science Translational Medicine, 13, eabd6434.; Thompson, R. H., & Swanson, L. W. ( 2003 ). Structural characterization of a hypothalamic visceromotor pattern generator network. Brain Research Reviews, 41, 153 – 202.; Versteeg, D. H. G., Bergen, P. V., Adan, R. A. H., & Wildt, D. J. D. ( 1998 ). Melanocortins and cardiovascular regulation. European Journal of Pharmacology, 360, 1 – 14.; Watts, A. G., Swanson, L. W., & Sanchez-Watts, G. ( 1987 ). Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. Journal of Comparative Neurology, 258, 204 – 229.; West, K. S., Lu, C., Olson, D. P., & Roseberry, A. G. ( 2019 ). Alpha-melanocyte stimulating hormone increases the activity of melanocortin-3 receptor-expressing neurons in the ventral tegmental area. Journal of Physiology, 597, 3217 – 3232.; Yang, Z., & Tao, Y. - X. ( 2016 ). Mutations in Melanocortin-3 receptor gene and human obesity. Progress in Molecular Biology and Translational Science, 140, 97 – 129.; Ye, J., & Veinante, P. ( 2019 ). Cell-type specific parallel circuits in the bed nucleus of the stria terminalis and the central nucleus of the amygdala of the mouse. Brain Structure and Function, 224, 1067 – 1095.; Andermann, M. L., & Lowell, B. B. ( 2017 ). Toward a wiring diagram understanding of appetite control. Neuron, 95, 757 – 778.; Begriche, K., Levasseur, P. R., Zhang, J., Rossi, J., Skorupa, D., Solt, L. A., Young, B., Burris, T. P., Marks, D. L., Mynatt, R. L., & Butler, A. A. ( 2011 ). Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis. Journal of Biological Chemistry, 286, 40771 – 40781.; Betley, J. N., Xu, S., Cao, Z. F. H., Gong, R., Magnus, C. J., Yu, Y., & Sternson, S. M. ( 2015 ). Neurons for hunger and thirst transmit a negative-valence teaching signal. Nature, 521, 180 – 185.; Biddinger, J. E., Lazarenko, R. M., Scott, M. M., & Simerly, R. ( 2020 ). Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus. eLife, 9, e59857.; Bria, A., Bernaschi, M., Guarrasi, M., & Iannello, G. ( 2019 ). Exploiting multi-level parallelism for stitching very large microscopy images. Frontiers in Neuroinformatics, 13, 41.; Burnett, C. J., Li, C., Webber, E., Tsaousidou, E., Xue, S. Y., Brüning, J. C., & Krashes, M. J. ( 2016 ). Hunger-driven motivational state competition. Neuron, 92, 187 – 201.; Butler, A. A. ( 2006 ). The melanocortin system and energy balance. Peptides, 27, 281 – 290.; Butler, A. A., & Cone, R. D. ( 2002 ). The melanocortin receptors: Lessons from knockout models. Neuropeptides, 36, 77 – 84.; Butler, A. A., Kesteson, R. A., Khong, K., Cullen, M. J., Pelleymounter, M. A., Dekoning, J., Baetscher, M., & Cone, R. D. ( 2000 ). A unique metalolic sysdrone causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology, 141, 3518 – 3521.; Butler, A. A., Marks, D. L., Fan, W., Kuhn, C. M., Bartolome, M., & Cone, R. D. ( 2001 ). Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nature Neuroscience, 4, 605 – 611.; Cai, H., Haubensak, W., Anthony, T. E., & Anderson, D. J. ( 2014 ). Central amygdala PKC-δ+ neurons mediate the influence of multiple anorexigenic signals. Nature Neuroscience, 17, 1240 – 1248.; Campos, C. A., Bowen, A. J., Roman, C. W., & Palmiter, R. D. ( 2018 ). Encoding of danger by parabrachial CGRP neurons. Nature, 555, 617 – 622.; Canteras, N. S., Simerly, R. B., & Swanson, L. W. ( 1994 ). Organization of projections from the ventromedial nucleus of the hypothalamus: A Phaseolus vulgaris -leucoagglutinin study in the rat. Journal of Comparative Neurology, 348, 41 – 79.; Canteras, N. S., Simerly, R. B., & Swanson, L. W. ( 1995 ). Organization of projections from the medial nucleus of the amygdala: A PHAL study in the rat. Journal of Comparative Neurology, 360, 213 – 245.; Canteras, N. S., & Swanson, L. W. ( 1992 ). Projections of the ventral subiculum to the amygdala, septum, and hypothalamus: A PHAL anterograde tract-tracing study in the rat. Journal of Comparative Neurology, 324, 180 – 194.; Catania, A., Gatti, S., Colombo, G., & Lipton, J. M. ( 2004 ). Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacological Reviews, 56, 1 – 29.; Chandramohan, G., Durham, N., Sinha, S., Norris, K., & Vaziri, N. D. ( 2009 ). Role of γ melanocyte-stimulating hormone–renal melanocortin 3 receptor system in blood pressure regulation in salt-resistant and salt-sensitive rats. Metabolism, 58, 1424 – 1429.; Chen, A. S., Marsh, D. J., Trumbauer, M. E., Frazier, E. G., Guan, X.-M., Yu, H., Rosenblum, C. I., Vongs, A., Feng, Y., Cao, L., Metzger, J. M., Strack, A. M., Camacho, R. E., Mellin, T. N., Nunes, C. N., Min, W., Fisher, J., Gopal-Truter, S., MacIntyre, D. E., … Ploeg, L. H. T. V. d. ( 2000 ). Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nature Genetics, 26, 97 – 102.; Chen, J. Y., Campos, C. A., Jarvie, B. C., & Palmiter, R. D. ( 2018 ). Parabrachial CGRP neurons establish and sustain aversive taste memories. Neuron, 100, 891 – 899.; Chen, Y., Lin, Y.-C., Zimmerman, C. A., Essner, R. A., & Knight, Z. A. ( 2016 ). Hunger neurons drive feeding through a sustained, positive reinforcement signal. eLife, 5, e18640.; Cone, R. D. ( 2006 ). Studies on the physiological functions of the melanocortin system. Endocrine Reviews, 27, 736 – 749.; Dean, K. M., Roudot, P., Welf, E. S., Danuser, G., & Fiolka, R. ( 2015 ). Deconvolution-free subcellular imaging with axially swept light sheet microscopy. Biophysical Journal, 108, 2807 – 2815.; Dong, H.-W., Petrovich, G. D., & Swanson, L. W. ( 2001 ). Topography of projections from amygdala to bed nuclei of the stria terminalis. Brain Research Reviews, 38, 192 – 246.; Dunigan, A. I., Olson, D. P., & Roseberry, A. G. ( 2021 ). VTA MC3R neurons control feeding in an activity- and sex-dependent manner in mice. Neuropharmacology, 197, 108746.; Ellacott, K. L. J., Murphy, J. G., Marks, D. L., & Cone, R. D. ( 2007 ). Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology, 148, 6186 – 6194.; Fan, W., Dinulescu, D. M., Butler, A. A., Zhou, J., Marks, D. L., & Cone, R. D. ( 2000 ). The central melanocortin system can directly regulate serum insulin levels. Endocrinology, 141, 3072 – 3079.; Fan, W., Ellacott, K. L. J., Halatchev, I. G., Takahashi, K., Yu, P., & Cone, R. D. ( 2004 ). Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system. Nature Neuroscience, 7, 335 – 336.; Fulwiler, C. E., & Saper, C. B. ( 1984 ). Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Research Reviews, 7, 229 – 259.; Gantz, I., Konda, Y., Tashiro, T., Shimoto, Y., Miwa, H., Munzert, G., Watson, S. J., DelValle, J., & Yamada, T. ( 1993 ). Molecular cloning of a novel melanocortin receptor. Journal of Biological Chemistry, 268, 8246 – 50.; Garfield, A. S., Lam, D. D., Marston, O. J., Przydzial, M. J., & Heisler, L. K. ( 2009 ). Role of central melanocortin pathways in energy homeostasis. Trends in Endocrinology & Metabolism, 20, 203 – 215.; Getting, S. J., Riffo-Vasquez, Y., Pitchford, S., Kaneva, M., Grieco, P., Page, C. P., Perretti, M., & Spina, D. ( 2008 ). A role for MC3R in modulating lung inflammation. Pulmonary Pharmacology & Therapeutics, 21, 866 – 873.; Ghamari-Langroudi, M., Cakir, I., Lippert, R. N., Sweeney, P., Litt, M. J., Ellacott, K. L. J., & Cone, R. D. ( 2018 ). Regulation of energy rheostasis by the melanocortin-3 receptor. Science Advances, 4, eaat0866.; Girardet, C., Marks, D. L., & Butler, A. A. ( 2018 ). Melanocortin-3 receptors expressed on agouti-related peptide neurons inhibit feeding behavior in female mice. Obesity, 26, 1849 – 1855.; Gu, G., Cornea, A., & Simerly, R. B. ( 2003 ). Sexual differentiation of projections from the principal nucleus of the bed nuclei of the stria terminalis. Journal of Comparative Neurology, 460, 542 – 562.; Hahn, J. D., & Swanson, L. W. ( 2012 ). Connections of the lateral hypothalamic area juxtadorsomedial region in the male rat. Journal of Comparative Neurology, 520, 1831 – 1890.; Hedde, P. N., & Gratton, E. ( 2018 ). Selective plane illumination microscopy with a light sheet of uniform thickness formed by an electrically tunable lens. Microscopy Research and Technique, 81, 924 – 928.; Hulsman, A. M., Terburg, D., Roelofs, K., & Klumpers, F. ( 2021 ). Roles of the bed nucleus of the stria terminalis and amygdala in fear reactions. Handbook of clinical neurology, (vol.) 179, pp. 419 – 432. Elsevier.; Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., Gu, W., Kesterson, R. A., Boston, B. A., Cone, R. D., Smith, F. J., Campfield, L. A., Burn, P., & Lee, F. ( 1997 ). Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell, 88, 131 – 141.; Hutton, L. A., Gu, G., & Simerly, R. B. ( 1998 ). Development of a sexually dimorphic projection from the bed nuclei of the stria terminalis to the anteroventral periventricular nucleus in the rat. Journal of Neuroscience, 18, 3003 – 3013.; Izadi, M. S., & Radahmadi, M. ( 2021 ). Overview of the central amygdala role in feeding behaviour. British Journal of Nutrition, 217, 953 – 960.; Jaramillo, A. A., Brown, J. A., & Winder, D. G. ( 2021 ). Danger and distress: Parabrachial-extended amygdala circuits. Neuropharmacology, 198, 108757.; Jaramillo, A. A., Williford, K. M., Marshall, C., Winder, D. G., & Centanni, S. W. ( 2020 ). BNST transient activity associates with approach behavior in a stressful environment and is modulated by the parabrachial nucleus. Neurobiology Stress, 13, 100247.; Kafami, M., & Nasimi, A. ( 2016 ). Contribution of amygdala to the pressor response elicited by microinjection of angiotensin II into the bed nucleus of the stria terminalis. Brain Research Bulletin, 127, 202 – 207.; Kamitakahara, A., Xu, B., & Simerly, R. ( 2016 ). Ventromedial hypothalamic expression of Bdnf is required to establish normal patterns of afferent GABAergic connectivity and responses to hypoglycemia. Molecular Metabolism, 5, 91 – 101.; Kim, M. S., Small, C. J., Russell, S. H., Morgan, D. G. A., Abbott, C. R., AlAhmed, S. H., Hay, D. L., Ghatei, M. A., Smith, D. M., & Bloom, S. R. ( 2002 ). Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: Evidence for the differential roles of melanocortin 3 and 4 receptors. Journal of Neuroendocrinology, 14, 276 – 282.; Kishi, T., Tsumori, T., Ono, K., Yokota, S., Ishino, H., & Yasui, Y. ( 2000 ). Topographical organization of projections from the subiculum to the hypothalamus in the rat. Journal of Comparative Neurology, 419, 205 – 222.; Lam, B. Y. H., Williamson, A., Finer, S., Day, F. R., Tadross, J. A., Soares, A. G., Wade, K., Sweeney, P., Bedenbaugh, M. N., Porter, D. T., Melvin, A., Ellacott, K. L. J., Lippert, R. N., Buller, S., Rosmaninho-Salgado, J., Dowsett, G. K. C., Ridley, K. E., Xu, Z., Cimino, I., … O’Rahilly, S. ( 2021 ). MC3R links nutritional state to childhood growth and the timing of puberty. Nature, 599, 436 – 441.; Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., Chen, L., Chen, L., Chen, T.-M., Chin, M. C., Chong, J., Crook, B. E., Czaplinska, A., Dang, C. N., Datta, S., … Wohnoutka, P. E. ( 2007 ). Genome-wide atlas of gene expression in the adult mouse brain. Nature, 445, 168 – 176.; Lippert, R. N., Ellacott, K. L. J., & Cone, R. D. ( 2014 ). Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice. Endocrinology, 155, 1718 – 1727.; Lu, J., Zhang, Y.-H., Chou, T. C., Gaus, S. E., Elmquist, J. K., Shiromani, P., & Saper, C. B. ( 2001 ). Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep–wake cycle and temperature regulation. Journal of Neuroscience, 21, 4864 – 4874.; Malick, A., Jakubowski, M., Elmquist, J. K., Saper, C. B., & Burstein, R. ( 2001 ). A neurohistochemical blueprint for pain-induced loss of appetite. Proceedings of the National Academy of Sciences, 98, 9930 – 9935.; Markakis, E. A., & Swanson, L. W. ( 1997 ). Spatiotemporal patterns of secretomotor neuron generation in the parvicellular neuroendocrine. Brain Research Reviews, 24, 255 – 291.; Marks, D. L., Butler, A. A., Turner, R., Brookhart, G., & Cone, R. D. ( 2003 ). Differential role of melanocortin receptor subtypes in cachexia. Endocrinology, 144, 1513 – 1523.; Marks, D. L., & Cone, R. D. ( 2003 ). The Role of the melanocortin-3 receptor in cachexia. Annals of the New York Academy of Sciences, 994, 258 – 266.; Mavrikaki, M., Girardet, C., Kern, A., Brantley, A. F., Miller, C. A., Macarthur, H., Marks, D. L., & Butler, A. A. ( 2016 ). Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight loss. Molecular Metabolism, 5, 566 – 579.; Mioni, C., Giuliani, D., Cainazzo, M. M., Leone, S., Iannone, C., Bazzani, C., Grieco, P., Novellino, E., Tomasi, A., Bertolini, A., & Guarini, S. ( 2003 ). Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors. European Journal of Pharmacology, 477, 227 – 234.; Moga, M. M., Saper, C. B., & Gray, T. S. ( 1989 ). Bed nucleus of the stria terminalis: Cytoarchitecture, immunohistochemistry, and projection to the parabrachial nucleus in the rat. Journal of Comparative Neurology, 283, 315 – 332.; Mohawk, J. A., Green, C. B., & Takahashi, J. S. ( 2012 ). Central and peripheral circadian clocks in mammals. Neuroscience, 35, 445 – 462.; Morens, C., Keijzer, M., Vries, K. D., Scheurink, A., & Dijk, G. V. ( 2005 ). Effects of high-fat diets with different carbohydrate-to-protein ratios on energy homeostasis in rats with impaired brain melanocortin receptor activity. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 289, R156 – R163.; Mountjoy, K. G., Mortrud, M. T., Low, M. J., Simerly, R. B., & Cone, R. D. ( 1994 ). Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Molecular Endocrinology, 8, 1298 – 1308.; Pandit, R., Omrani, A., Luijendijk, M. C. M., Vrind, V. A. J. d., Rozen, A. J. V., Ophuis, R., Garner, K., Kallo, I., Ghanem, A., Liposits, Z., Conzelmann, K.-K., Vanderschuren, L., Fleur, S. E. l., & Adan, R. A. H. ( 2016 ). Melanocortin 3 receptor signaling in midbrain dopamine neurons increases the motivation for food reward. Neuropsychopharmacol, 41, 2241 – 2251.; Park, Y.-G., Sohn, C. H., Chen, R., McCue, M., Yun, D. H., Drummond, G. T., Ku, T., Evans, N. B., Oak, H. C., Trieu, W., Choi, H., Jin, X., Lilascharoen, V., Wang, J., Truttmann, M. C., Qi, H. W., Ploegh, H. L., Golub, T. R., Chen, S.-C., … Chung, K. ( 2019 ). Protection of tissue physicochemical properties using polyfunctional crosslinkers. Nature Biotechnology, 37, 73 – 83.; Pei, H., Patterson, C. M., Sutton, A. K., Burnett, K. H., Myers, M. G., & Olson, D. P. ( 2019 ). Lateral hypothalamic Mc3R-expressing neurons modulate locomotor activity, energy expenditure, and adiposity in male mice. Endocrinology, 160, 343 – 358.; Petrovich, G. D., Risold, P. Y., & Swanson, L. W. ( 1996 ). Organization of projections from the basomedial nucleus of the amygdala: A PHAL study in the rat. Journal of Comparative Neurology, 374, 387 – 420.; Petrovich, G. D., & Swanson, L. W. ( 1997 ). Projections from the lateral part of the central amygdalar nucleus to the postulated fear conditioning circuit. Brain Research, 763, 247 – 254.; Polston, E. K., Gu, G., & Simerly, R. B. ( 2004 ). Neurons in the principal nucleus of the bed nuclei of the stria terminalis provide sexually dimorphic GABAergic input to the anteroventral periventricular nucleus of the hypothalamus. Neuroscience, 123, 793 – 803.; Polston, E. K., & Simerly, R. B. ( 2003 ). Sex-specific patterns of galanin, cholecystokinin, and substance P expression in neurons of the principal bed nucleus of the stria terminalis are differentially reflected within three efferent preoptic pathways in the juvenile rat. Journal of Comparative Neurology, 465, 551 – 559.; Renquist, B. J., Lippert, R. N., Sebag, J. A., Ellacott, K. L. J., & Cone, R. D. ( 2011 ). Physiological roles of the melanocortin MC3 receptor. European Journal of Pharmacology, 660, 13 – 20.; Risold, P. Y., Canteras, N. S., & Swanson, L. W. ( 1994 ). Organization of projections from the anterior hypothalamic nucleus: A Phaseolus vulgaris -leucoagglutinin study in the rat. Journal of Comparative Neurology, 348, 1 – 40.

الإتاحة: https://doi.org/10.1002/cne.25379Test
https://hdl.handle.net/2027.42/174918Test