التفاصيل البيبلوغرافية
| العنوان: |
Prevalence and circulant genotypes of Chlamydia trachomatis in university women from cities in the Brazilian Amazon |
| المؤلفون: |
dos Santos, Leonardo Miranda, Vieira, Maria Renata Mendonça dos Santos, Vieira, Rodrigo Covre, Silva, Lídia Bolivar da Luz, de Macêdo, Geraldo Mariano Moraes, Miranda, Angélica Espinosa, Brasiliense, Danielle Murici, e Guimarães, Ricardo José de Paula Souza, Sousa, Edivaldo Costa, Ferrari, Stephen Francis, Pinheiro, Helder Henrique Costa, Ishikawa, Edna Aoba Yassui, de Sousa, Maísa Silva |
| المساهمون: |
Freitas, André Ricardo Ribas |
| المصدر: |
PLOS ONE ; volume 19, issue 1, page e0287119 ; ISSN 1932-6203 |
| بيانات النشر: |
Public Library of Science (PLoS) |
| سنة النشر: |
2024 |
| المجموعة: |
PLOS Publications (via CrossRef) |
| الوصف: |
Background Approximately 80% of infected women infected by Chlamydia trachomatis are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydia infection and genotypes are available in Amazonian communities. Objectives To describe the prevalence of and associated factors and to identify the genotypes of sexual C . trachomatis infection in female university students in different urban centers (capital and interiors) in the Brazilian state of Pará, in the eastern Amazon region. Methods A cross-sectional study was performed among young women attending public universities in four different urban centers in the eastern Amazon region. They were invited to participate in the studt and cervical secretions were collected for molecular diagnosis of C . trachomatis . We utilized amplification of the ompA gene by nested PCR. Positive samples were genotyped by nucleotide sequencing. Study participants completed a questionnaire on social, epidemiological, and reproductive health variables. A Qui-square and Binominal regression test were used to evaluate the degree of association of these variables with the infection. Results A total of 686 female students was included in the study. The overall prevalence of C . trachomatis was 11.2% (77/686). The prevalence of this infection was higher in interiors (15.2% vs 9.5%/ p : 0.0443). Female university students who do not have a sexual partner (11.8%/ p <0.008), who do not use a condom in their sexual relations (17.8%/ p <0.0001) and who reported having suffered a miscarriage (32%/ p <0.0001) have high chances of acquiring this sexual infection. The ompA gene was sequenced in only 33 (42.8%) samples, revealing the genotype J was the most frequent (27.2% [9/33]), followed by genotypes D (24.2% [8/33]), and then genotypes F (18.2% [6/33]), E (15.1% [5/33]) K (6.1% [2/33]), Ia (6.1% [2/33]), and G (3.1% [1/33]). Conclusions The high prevalence of sexual infection by C . trachomatis in the female university ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1371/journal.pone.0287119 |
| الإتاحة: |
https://doi.org/10.1371/journal.pone.0287119Test |
| حقوق: |
http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.C3722685 |
| قاعدة البيانات: |
BASE |
