نتائج البحث - "Signal Transduction/*drug effects"

1

دورية أكاديمية

Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells

المساهمون: Evan R Abt, Thuc M Le, Amanda M Dann, Joseph R Capri, Soumya Poddar, Vincent Lok, Luyi Li, Keke Liang, Amanda L Creech, Khalid Rashid, Woosuk Kim, Nanping Wu, Jing Cui, Arthur Cho, Hailey Rose Lee, Ethan W Rosser, Jason M Link, Johannes Czernin, Ting-Ting Wu, Robert Damoiseaux, David W Dawson, Timothy R Donahue, Caius G Radu, Cho, Arthur Eung Hyuck

مصطلحات موضوعية: Adenocarcinoma / metabolism, Adenocarcinoma / pathology, Animals, Ataxia Telangiectasia Mutated Proteins / antagonists & inhibitors, Ataxia Telangiectasia Mutated Proteins / metabolism, Carcinoma, Pancreatic Ductal / metabolism, Pancreatic Ductal / pathology, Cell Cycle Checkpoints / drug effects, Cell Line, Tumor, DNA Damage / drug effects, Female, Humans, Interferon Type I / metabolism, Interferon Type I / pharmacology, Male, Membrane Proteins / metabolism, Mice, Inbred NOD, Nucleotides / antagonists & inhibitors, Nucleotides / biosynthesis, Nucleotides / metabolism, Pancreatic Neoplasms / pathology, Protein Kinase Inhibitors / pharmacology, Signal Transduction / drug effects, Xenograft Model Antitumor Assays, STING, interferon, nucleotide metabolism

العلاقة: CELL REPORTS; J00488; OAK-2022-05501; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191177Test; T202204764; CELL REPORTS, Vol.38(2) : 110236, 2022-01

الإتاحة: https://doi.org/10.1016/j.celrep.2021.110236Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191177Test

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النص الكامل

2

دورية أكاديمية

Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway

المؤلفون: Yang, Xiaorong, Zhang, Hongmei, Wu, Jinzi, Yin, Litian, Yan, Liang-Jun, Zhang, Ce

المصدر: International Journal of Molecular Sciences

مصطلحات موضوعية: Hn, MAPKs, Nmda, Ros, excitotoxicity, neuroprotection, Animals, Intracellular Signaling Peptides and Proteins / pharmacology, MAP Kinase Signaling System / drug effects, Mitogen-Activated Protein Kinases / metabolism, N-Methylaspartate / toxicity, Rats, Wistar, Reactive Oxygen Species / metabolism, Signal Transduction / drug effects, p38 Mitogen-Activated Protein Kinases / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/ijms19102982Test; Yang, X., Zhang, H., Wu, J., Yin, L., Yan, L. J., & Zhang, C. (2018). Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway. International journal of molecular sciences, 19(10), 2982. https://doi.org/10.3390/ijms19102982Test; https://hdl.handle.net/20.500.12503/31564Test; 19; 10

الإتاحة: https://doi.org/20.500.12503/31564Test
https://doi.org/10.3390/ijms19102982Test
https://hdl.handle.net/20.500.12503/31564Test

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النص الكامل

3

دورية أكاديمية

Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging

المؤلفون: Yu, Mengdi, Zhang, Hongxia, Wang, Brian, Zhang, Yinuo, Zheng, Xiaoying, Shao, Bei, Zhuge, Qichuan, Jin, Kunlin

المصدر: Cells

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/cells10030660Test; Yu, M., Zhang, H., Wang, B., Zhang, Y., Zheng, X., Shao, B., Zhuge, Q., & Jin, K. (2021). Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging. Cells, 10(3), 660. https://doi.org/10.3390/cells10030660Test; https://hdl.handle.net/20.500.12503/31700Test; 10

الإتاحة: https://doi.org/20.500.12503/31700Test
https://doi.org/10.3390/cells10030660Test
https://hdl.handle.net/20.500.12503/31700Test

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النص الكامل

4

دورية أكاديمية

Loss of Integrin-linked kinase sensitizes breast cancer to SRC inhibitors

المؤلفون: Beetham, Henry, Griffith, Billie G. C., Murina, Olga, Loftus, Alexander E. P., Parry, David A., Temps, Carolin, Culley, Jayne, Muir, Morwenna, Unciti-Broceta, Asier, Sims, Andrew H., Byron, Adam, Brunton, Valerie G.

المصدر: Beetham , H , Griffith , B G C , Murina , O , Loftus , A E P , Parry , D A , Temps , C , Culley , J , Muir , M , Unciti-Broceta , A , Sims , A H , Byron , A & Brunton , V G 2022 , ' Loss of Integrin-linked kinase sensitizes breast cancer to SRC inhibitors ' , Cancer Research , vol. 82 , no. 4 , pp. 632-647 . https://doi.org/10.1158/0008-5472.CAN-21-0373Test