نتائج البحث - "Siew-Kwan Koh"

1

دورية أكاديمية

Topical and oral peroxisome proliferator-activated receptor-α agonist ameliorates diabetic corneal neuropathy

المؤلفون: Hassan Mansoor, Isabelle Xin Yu Lee, Molly Tzu-Yu Lin, Heng Pei Ang, Yao Cong Xue, L. Krishaa, Moushmi Patil, Siew-Kwan Koh, Hong Chang Tan, Lei Zhou, Yu-Chi Liu

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2045-2322Test

الوصول الحر: https://doaj.org/article/6fb21aa24db74e17b58852abe9658545Test

View record in DOAJ

النص الكامل

2

دورية أكاديمية

Comparison of tear proteomic and neuromediator profiles changes between small incision lenticule extraction (SMILE) and femtosecond laser-assisted in-situ keratomileusis (LASIK)

المؤلفون: Yu-Chi Liu, Gary Hin-Fai Yam, Molly Tzu-Yu Lin, Ericia Teo, Siew-Kwan Koh, Lu Deng, Lei Zhou, Louis Tong, Jodhbir S. Mehta

المصدر: Journal of Advanced Research, Vol 29, Iss , Pp 67-81 (2021)

مصطلحات موضوعية: Tear, Proteomics, Neuromediators, Small incision lenticule extraction, Laser-assisted in-situ keratomileusis, Dry eye, Medicine (General), R5-920, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2090123220302277Test; https://doaj.org/toc/2090-1232Test

الوصول الحر: https://doaj.org/article/20059135a66a4cd485eb44db2ff370e3Test

View record in DOAJ

النص الكامل

3

دورية أكاديمية

Proteomic analysis of s-acylated proteins in human retinal pigment epithelial cells and the role of palmitoylation of Niemann-Pick type C1 protein in cholesterol transport

المؤلفون: Jia Kai Li, Yu Qing Rao, Siew Kwan Koh, Peiquan Zhao, Lei Zhou, Jing Li

المصدر: Frontiers in Aging Neuroscience, Vol 14 (2022)

مصطلحات موضوعية: retinal pigment epithelial cells, palmitoylation, Niemann-Pick type C1 protein, protein post-translational modification, cholesterol transport, acyl-biotin exchange (ABE), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnagi.2022.965943/fullTest; https://doaj.org/toc/1663-4365Test

الوصول الحر: https://doaj.org/article/1b4b0ab7692f45d3956a530e6aa46267Test

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النص الكامل

4

دورية أكاديمية

Increased Protein S-Glutathionylation in Leber’s Hereditary Optic Neuropathy (LHON)

المؤلفون: Lei Zhou, James Chun Yip Chan, Stephanie Chupin, Naïg Gueguen, Valérie Desquiret-Dumas, Siew Kwan Koh, Jianguo Li, Yan Gao, Lu Deng, Chandra Verma, Roger W Beuerman, Eric Chun Yong Chan, Dan Milea, Pascal Reynier

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 8; Pages: 3027

مصطلحات موضوعية: Leber’s Hereditary Optic Neuropathy, LHON, S -glutathionylation, proteomics, mitochondrial Complex I

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms21083027Test

الإتاحة: https://doi.org/10.3390/ijms21083027Test

View record in BASE

5

Release of frustration drives corneal amyloid disaggregation by brain chaperone

المؤلفون: Jia Yi Kimberly Low, Xiangyan Shi, Venkatraman Anandalakshmi, Dawn Neo, Gary Swee Lim Peh, Siew Kwan Koh, Lei Zhou, M. K. Abdul Rahim, Ketti Boo, JiaXuan Lee, Harini Mohanram, Reema Alag, Yuguang Mu, Jodhbir S. Mehta, Konstantin Pervushin

المساهمون: School of Biological Sciences

مصطلحات موضوعية: Medicine (miscellaneous), Biological sciences [Science], General Agricultural and Biological Sciences, Amyloid Beta Protein, General Biochemistry, Genetics and Molecular Biology, Hereditary Corneal Dystrophy

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7c7cc77c6644353199b7f79f7d7267Test
https://hdl.handle.net/10356/169296Test

6

Oral Peroxisome Proliferator-Activated Receptor-Alpha (PPAR)-α Agonist Enhances Corneal Nerve Regeneration in Patients with Type II Diabetes Mellitus

المؤلفون: Calesta Hui Yi Teo, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Siew-Kwan Koh, Lei Zhou, Dylan Shaoying Goh, Hyungwon Choi, Hiromi Wai Ling Koh, Amanda Yun Rui Lam, Paik Shia Lim, Jodhbir S. Mehta, Jean-Paul Kovalik, Thomas M. Coffman, Hong Chang Tan, Yu-Chi Liu

المصدر: Diabetes.

مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Internal Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6f404b03cb0254b2c07992b0b99cf1Test
https://pubmed.ncbi.nlm.nih.gov/36445944Test

7

Infigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4

المؤلفون: Jian Wei Teng, Mei Lin Go, Lloyd Wei Tat Tang, Hao Fan, Ravi Kumar Verma, Eric Chun Yong Chan, Lei Zhou, Siew Kwan Koh

المصدر: Drug Metabolism and Disposition. 49:856-868

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5efa437f38ef0c673c780016c9dc5aTest
https://doi.org/10.1124/dmd.121.000508Test

8

Direct and Sequential Bioactivation of Pemigatinib to a Reactive Iminium Ion Intermediate Culminates in Mechanism‐Based Inactivation of Cytochrome P450 3A

المؤلفون: Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan, Eric Chun Yong Chan

المصدر: The FASEB Journal. 36

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::430c05225d14b3fead0cd5932677c23fTest
https://doi.org/10.1096/fasebj.2022.36.s1.0r684Test

9

Metabolic Activation of the Acrylamide Michael Acceptor Warhead in Futibatinib to an Epoxide Intermediate Engenders Covalent Inactivation of CYP3A

المؤلفون: Lloyd Wei Tat Tang, Jiaxin Fu, Siew Kwan Koh, Guoyi Wu, Lei Zhou, Eric Chun Yong Chan

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 50(7)

مصطلحات موضوعية: Pharmacology, Activation, Metabolic, Acrylamide, Pyrimidines, Renal Dialysis, Pharmaceutical Science, Cytochrome P-450 CYP3A, Epoxy Compounds, Pyrazoles, Pyrroles

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701a45e19d7c0d746de0046c7f2276f4Test
https://pubmed.ncbi.nlm.nih.gov/35512804Test

10

Comparison of tear proteomic and neuromediator profiles changes between small incision lenticule extraction (SMILE) and femtosecond laser-assisted in-situ keratomileusis (LASIK)

المؤلفون: Louis Tong, Siew-Kwan Koh, Gary Hin-Fai Yam, Lei Zhou, Lu Deng, Molly Tzu-Yu Lin, Yu-Chi Liu, Ericia Teo, Jodhbir S. Mehta

المصدر: Journal of Advanced Research
Journal of Advanced Research, Vol 29, Iss, Pp 67-81 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Proteomics, Leukocyte migration, genetic structures, Corneal Surgery, Laser, medicine.medical_treatment, Keratomileusis, Laser In Situ, Surgical Wound, Keratomileusis, Cornea, 0302 clinical medicine, Endopeptidase activity, Basic and Biological Science, Neuromediators, Refractive surgery, Myopia, Postoperative Period, Extracellular structure organization, lcsh:R5-920, Multidisciplinary, Laser-assisted in-situ keratomileusis, Small incision lenticule extraction, Laser assisted, Receptors, Neurotransmitter, 030220 oncology & carcinogenesis, Dry Eye Syndromes, Female, Lasers, Excimer, lcsh:Medicine (General), Adult, medicine.medical_specialty, Dry eye, Young Adult, 03 medical and health sciences, Ophthalmology, Endopeptidases, medicine, Humans, Nerve Growth Factors, lcsh:Science (General), ComputingMethodologies_COMPUTERGRAPHICS, Wound Healing, business.industry, Mucins, LASIK, eye diseases, 030104 developmental biology, Tear, Tears, sense organs, business, lcsh:Q1-390

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ee6331828b74fd9904651b4d73ed59Test
http://europepmc.org/articles/PMC8020296Test

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