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1
المؤلفون: Kevin R. Webster, Siegfried H. Reich, Justin T. Ernst, Paul A. Sprengeler, Chinh Tran, Theodore Michels, Garrick K. Packard, Christian Nilewski, Alan Xiang, Samuel Sperry, Jeff Clarine, Andres Nevarez, Christopher J. Wegerski, Adina Gerson-Gurwitz, Gary G. Chiang, Jocelyn Staunton, Ana Parra, Eric Sung, Haleigh Howard, Maria Barrera, Joan Chen, Sarah Fish, Nathan P. Young, Boreth Eam, Peggy A. Thompson
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1650a320f50adfe95d94d63fa8b72d9eTest
https://doi.org/10.1158/1535-7163.c.6542892.v1Test -
2
المؤلفون: Kevin R. Webster, Siegfried H. Reich, Justin T. Ernst, Paul A. Sprengeler, Chinh Tran, Theodore Michels, Garrick K. Packard, Christian Nilewski, Alan Xiang, Samuel Sperry, Jeff Clarine, Andres Nevarez, Christopher J. Wegerski, Adina Gerson-Gurwitz, Gary G. Chiang, Jocelyn Staunton, Ana Parra, Eric Sung, Haleigh Howard, Maria Barrera, Joan Chen, Sarah Fish, Nathan P. Young, Boreth Eam, Peggy A. Thompson
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b76301f84d3ad65de199ac1ded585cTest
https://doi.org/10.1158/1535-7163.22521054.v1Test -
3
المؤلفون: Siegfried H. Reich, Stephen K. Burley, Spencer Emtage, Stephen R. Wasserman, Kevin Holme, Shane Atwell, Laura A. Pelletier, Lydia Smyth, Devon A. Thompson, Paul A. Sprengeler, Jeff M. Blaney, Tuan H. Do, Barbara C. Leon, Jason Adams, Isabelle A. Rooney, Marijane Russell, Kenneth D. Schwinn, J. Michael Sauder, Steve F. Gessert, Brandon E. Aubol, Marshall C. Peterman, Karen J. Froning, Jeremy D. Felce, Nanni H. Huser, Crystal M. Tang, Katti A. Jessen, Pierre-Yves Bounaud, Christopher R. Smith, Patrick S. Lee, Jorg Hendle, Sean G. Buchanan
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b253da2b8af69b57f61a86d3221a13f9Test
https://doi.org/10.1158/1535-7163.22485138Test -
4
المؤلفون: Siegfried H. Reich, Stephen K. Burley, Spencer Emtage, Stephen R. Wasserman, Kevin Holme, Shane Atwell, Laura A. Pelletier, Lydia Smyth, Devon A. Thompson, Paul A. Sprengeler, Jeff M. Blaney, Tuan H. Do, Barbara C. Leon, Jason Adams, Isabelle A. Rooney, Marijane Russell, Kenneth D. Schwinn, J. Michael Sauder, Steve F. Gessert, Brandon E. Aubol, Marshall C. Peterman, Karen J. Froning, Jeremy D. Felce, Nanni H. Huser, Crystal M. Tang, Katti A. Jessen, Pierre-Yves Bounaud, Christopher R. Smith, Patrick S. Lee, Jorg Hendle, Sean G. Buchanan
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee53a296e3d5b8a6d460e10e97860b5aTest
https://doi.org/10.1158/1535-7163.22485141.v1Test -
5
المؤلفون: Siegfried H. Reich, Stephen K. Burley, Spencer Emtage, Stephen R. Wasserman, Kevin Holme, Shane Atwell, Laura A. Pelletier, Lydia Smyth, Devon A. Thompson, Paul A. Sprengeler, Jeff M. Blaney, Tuan H. Do, Barbara C. Leon, Jason Adams, Isabelle A. Rooney, Marijane Russell, Kenneth D. Schwinn, J. Michael Sauder, Steve F. Gessert, Brandon E. Aubol, Marshall C. Peterman, Karen J. Froning, Jeremy D. Felce, Nanni H. Huser, Crystal M. Tang, Katti A. Jessen, Pierre-Yves Bounaud, Christopher R. Smith, Patrick S. Lee, Jorg Hendle, Sean G. Buchanan
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265be7461b5631c4751aa9dac9de05d6Test
https://doi.org/10.1158/1535-7163.c.6531795.v1Test -
6
المؤلفون: Evan Rogers, Paul A. Sprengeler, Brion W. Murray, Dayong Zhai, Armin Graber, Alexander Drilon, Xi Chen, Benjamin Solomon, Xin Zhang, Shanna Stopatschinskaja, Benjamin Besse, Wei Deng, Siegfried H. Reich
المصدر: Molecular cancer therapeutics. 20(12)
مصطلحات موضوعية: Models, Molecular, Cancer Research, Macrocyclic Compounds, Arginine, Oncogene Proteins, Fusion, Chemistry, Mutant, Entrectinib, Tropomyosin receptor kinase A, Fusion protein, Molecular biology, Oncology, Trk receptor, Neoplasms, Mutation, Potency, Humans, Pyrazoles, Tumor xenograft
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370c53a3897bd702c6ef8da93a4de9c7Test
https://pubmed.ncbi.nlm.nih.gov/34625502Test -
7
المؤلفون: Wei Deng, Paul A. Sprengeler, Alexander Drilon, Dayong Zhai, Brion W. Murray, Siegfried H. Reich, Xi Chen, Evan Rogers
المصدر: Cancer Research. 81:1119-1119
مصطلحات موضوعية: Cancer Research, Chemistry, Mutant, Wild type, Cancer, Entrectinib, Tropomyosin receptor kinase A, medicine.disease, Fusion protein, Molecular biology, nervous system, Oncology, Trk receptor, medicine, IC50
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ba031e428761ea563fe2ba988a0b82bbTest
https://doi.org/10.1158/1538-7445.am2021-1119Test -
8
المؤلفون: S. D. Hatch, Mark A. Muesing, Deborah A. Khalil, Nickolay Y. Chirgadze, Siegfried H. Reich, Vincent J. Kalish, Kenneth S. Su, Jeffrey A. Burgess, Krzysztof Appelt, Bruce A. Dressman, Penny P. Lubbehusen, Stephen W. Kaldor, Bhasker V. Shetty, Kristina M. Campanale, Jay F. Davies, David K. Clawson, John H. Tatlock, Maha B. Kosa, James E. Fritz, Amy K. Patick
المصدر: Journal of Medicinal Chemistry. 40:3979-3985
مصطلحات موضوعية: Male, Anti-HIV Agents, medicine.medical_treatment, Administration, Oral, Biological Availability, Rats, Sprague-Dawley, Structure-Activity Relationship, Dogs, HIV-1 protease, Pharmacokinetics, Oral administration, In vivo, Drug Discovery, medicine, Animals, Structure–activity relationship, Nelfinavir, Protease, Dose-Response Relationship, Drug, biology, Chemistry, Callithrix, HIV Protease Inhibitors, Rats, Macaca fascicularis, Biochemistry, Enzyme inhibitor, HIV-1, biology.protein, Molecular Medicine, Female, Nelfinavir mesylate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a5e189e8078b8e21586a61aa6a6a51Test
https://doi.org/10.1021/jm9704098Test -
9
المؤلفون: Siegfried H. Reich, et al. et al.
المصدر: ChemInform. 31
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Design synthesis, Stereochemistry, medicine, Structure based, General Medicine, Rhinovirus, 3c protease, medicine.disease_cause, Benzamide, Biological evaluation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d39668b26f5f080096b631790bd2e5d8Test
https://doi.org/10.1002/chin.200030078Test -
10
المؤلفون: Jeff Blaney, Pierre-Yves Bounaud, Sean Buchanan, Barbara C. Leon, Laura A. Pelletier, Kenneth D. Schwinn, Kevin Holme, Jorg Hendle, S. Emtage, Marshall C. Peterman, Shane Atwell, Paul A. Sprengeler, Patrick Lee, Crystal Tang, Tuan H. Do, Katti A. Jessen, Siegfried H. Reich, Brandon E. Aubol, Isabelle Rooney, Marijane Russell, Nanni Huser, D.A. Thompson, Steve F. Gessert, Lydia Smyth, Jeremy Felce, J. Michael Sauder, Christopher Ronald Smith, Jason Adams, S.R. Wasserman, Stephen K. Burley, Karen Froning
المصدر: Molecular cancer therapeutics. 8(12)
مصطلحات موضوعية: Models, Molecular, Cancer Research, Mice, Nude, Biology, Catalysis, Protein Structure, Secondary, Cell Line, Mice, Adenosine Triphosphate, In vivo, Cell Movement, Cell Line, Tumor, Neoplasms, Animals, Humans, Tyrosine, Phosphorylation, Autocrine signalling, Protein kinase A, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Cell growth, Proto-Oncogene Proteins c-met, Triazoles, Xenograft Model Antitumor Assays, Protein Structure, Tertiary, Tumor Burden, Pyridazines, Kinetics, Oncology, Cell culture, Acetylation, Cancer research, Female, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c26c5358efb0d1522269f925d044537Test
https://pubmed.ncbi.nlm.nih.gov/19934279Test