المؤلفون: Yuyun Li, Yan Wu, Siyan Li, Yibin Li, Xin Zhang, Zeren Shou, Shuyin Gu, Chenliang Zhou, Daohua Xu, Kangni Zhao, Suiyi Tan, Jiayin Qiu, Xiaoyan Pan, Lin Li

المصدر: Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113946- (2022)

مصطلحات موضوعية: COVID-19, Qingfei Paidu Decoction, SARS-CoV-2, Bioinformatics, Systematic pharmacology, Virus-host interactome, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S075333222201335XTest; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/03dd0b6439364a238348ec33012afea9Test

المؤلفون: Shuyin Gu (6494009), Kai Chen (129938), Yezhi Jin (11305534), Xiaoning Yang (1529320)

مصطلحات موضوعية: Biophysics, Biochemistry, Ecology, Computational Biology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Graphene oxide (GO), air-water interface, adsorption, free-energy, molecular simulation

العلاقة: https://figshare.com/articles/journal_contribution/Molecular_simulation_of_adsorption_thermodynamics_and_dynamics_behavior_of_GOs_at_air-water_interface/15624520Test

الإتاحة: https://doi.org/10.6084/m9.figshare.15624520.v1Test

المؤلفون: Jian Rong (598108), Wakana Mori (1428892), Xiaotian Xia (402177), Michael A. Schafroth (1771792), Chunyu Zhao (1977382), Richard S. Van (7435541), Tomoteru Yamasaki (136789), Jiahui Chen (1818361), Zhiwei Xiao (1723447), Ahmed Haider (5628896), Daisuke Ogasawara (1452202), Atsuto Hiraishi (11485143), Tuo Shao (6407981), Yiding Zhang (1428880), Zhen Chen (129176), Fuwen Pang (11485146), Kuan Hu (3349553), Lin Xie (136792), Masayuki Fujinaga (136798), Katsushi Kumata (136795), Yuancheng Gou (302338), Yang Fang (566232), Shuyin Gu (6494009), Huiyi Wei (11368483), Liang Bao (214906), Hao Xu (6530), Thomas L. Collier (3637486), Yihan Shao (1338777), Richard E. Carson (2563657), Benjamin F. Cravatt (93774), Lu Wang (45927), Ming-Rong Zhang (136828), Steven H. Liang (1341546)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Science Policy, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, treating psychiatric disorders, positron emission tomography, piperazinyl azetidine scaffold, high radiochemical yields, heterogeneous radioactivity distribution, good specific binding, favorable molar activity, central nervous system, attractive therapeutic concept, adequate brain kinetics, f ]< b, 15 , 10 , suitable pet radioligand, binding pet ligands, f ]­ magl, 18 , [< sup, ([< sup, thus channeling

العلاقة: https://figshare.com/articles/journal_contribution/Novel_Reversible-Binding_PET_Ligands_for_Imaging_Monoacylglycerol_Lipase_Based_on_the_Piperazinyl_Azetidine_Scaffold/16685586Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00747.s001Test

المؤلفون: Shuyin Gu (6494009), Zhijun Xu (1708078), Xiaoning Yang (1529320)

مصطلحات موضوعية: Biophysics, Biochemistry, Ecology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, simulation results, oxygen-containing groups, Molecular Insight, interface affinity, dynamics behavior, graphene oxide, adsorption thermodynamics, adsorption mechanism, oxidization degree, material preparations, GO, Interfacial Behavior, Molecular-level understanding, interaction, nanosheet, anisotropic 2- D translation

العلاقة: https://figshare.com/articles/journal_contribution/Molecular_Insight_into_the_Adsorption_Thermodynamics_and_Interfacial_Behavior_of_GOs_at_the_Liquid_Liquid_Interface/13868619Test

الإتاحة: https://doi.org/10.1021/acs.jpcb.0c10118.s001Test

المؤلفون: Xin Mao, Shuyin Gu, Huiting Sang, Yilu Ye, Jingyan Li, Yunxia Teng, Feiyu Zhang, Qinhai Ma, Ping Jiang, Zifeng Yang, Weizhong Huang, Shuwen Liu

المصدر: Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)

مصطلحات موضوعية: Other systems of medicine, RZ201-999

العلاقة: http://dx.doi.org/10.1155/2021/5547424Test; https://doaj.org/toc/1741-427XTest; https://doaj.org/toc/1741-4288Test; https://doaj.org/article/059dc3dba7a84242a394a17c37e4d120Test

الإتاحة: https://doi.org/10.1155/2021/5547424Test
https://doaj.org/article/059dc3dba7a84242a394a17c37e4d120Test

المؤلفون: Ahmed Haider, Jian Rong, Steven H. Liang, Huiyi Wei, Daisuke Ogasawara, Masayuki Fujinaga, Tuo Shao, Wakana Mori, Shuyin Gu, Hao Xu, Michael A. Schafroth, Lin Xie, Yuancheng Gou, Ming-Rong Zhang, Thomas Lee Collier, Jiahui Chen, Katsushi Kumata, Zhen Chen, Richard Van, Yihan Shao, Lu Wang, Zhiwei Xiao, Xiaotian Xia, Kuan Hu, Bao Liang, Tomoteru Yamasaki, Richard E. Carson, Yiding Zhang, Fuwen Pang, Benjamin F. Cravatt, Yang Fang, Chunyu Zhao, Atsuto Hiraishi

المصدر: J Med Chem

مصطلحات موضوعية: Models, Molecular, Azetidine, Ligands, 01 natural sciences, Article, Proinflammatory cytokine, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Radioligand, Animals, Distribution (pharmacology), 030304 developmental biology, Serine protease, 0303 health sciences, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Haplorhini, Monoacylglycerol Lipases, Rats, 0104 chemical sciences, 3. Good health, Monoacylglycerol lipase, Eicosanoid, chemistry, Biochemistry, Positron-Emission Tomography, biology.protein, Azetidines, Molecular Medicine, Arachidonic acid, Radiopharmaceuticals

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d13650994fb578b1cd216abc002e41fTest
https://doi.org/10.1021/acs.jmedchem.1c00747Test

المؤلفون: Xiaoning Yang, Zhijun Xu, Shuyin Gu

المصدر: The Journal of Physical Chemistry B. 125:1924-1935

مصطلحات موضوعية: Materials science, 010304 chemical physics, Graphene, Oxide, Thermodynamics, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Surfaces, Coatings and Films, law.invention, Surface tension, chemistry.chemical_compound, Adsorption, Deprotonation, chemistry, law, 0103 physical sciences, Materials Chemistry, Liquid liquid, Physical and Theoretical Chemistry, Anisotropy, Interfacial morphology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790db2c77b6efab2688693b83c5c8544Test
https://doi.org/10.1021/acs.jpcb.0c10118Test

المؤلفون: Yilu Ye, Shuyin Gu, Taizhen Liang, Shuwen Liu, Qiao Zhang

المصدر: Microbes and Infection. 22:576-584

مصطلحات موضوعية: 0301 basic medicine, Chemokine, Nuclear Receptor Coactivators, 030106 microbiology, Immunology, IκB kinase, Protein Serine-Threonine Kinases, Biology, Virus Replication, medicine.disease_cause, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, TANK-binding kinase 1, Interferon, Influenza A virus, medicine, Humans, CXCL10, Phosphorylation, Innate immune system, Transcription Factor RelA, NF-κB, Interferon-beta, Immunity, Innate, I-kappa B Kinase, Cell biology, HEK293 Cells, STAT1 Transcription Factor, 030104 developmental biology, Infectious Diseases, chemistry, A549 Cells, biology.protein, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d779b49fb647242c0320c6c57e15b7aTest
https://doi.org/10.1016/j.micinf.2020.07.009Test

المؤلفون: Wenjiao Wu, Shuyin Gu, Shuwen Liu, Qiao Zhang, Yingyuan Zhong, Lizhu Chen, Yilu Ye, Qi Huang, Mingkai Feng

المصدر: J Virol

مصطلحات موضوعية: Immunology, Virus Replication, Microbiology, Guanylate-binding protein, Proinflammatory cytokine, Mice, 03 medical and health sciences, chemistry.chemical_compound, Immune system, Orthomyxoviridae Infections, GTP-Binding Proteins, Interferon, Virology, medicine, Animals, Humans, STAT1, Phosphorylation, STAT2, Lung, Cells, Cultured, Immune Evasion, 030304 developmental biology, 0303 health sciences, Innate immune system, biology, 030306 microbiology, NF-kappa B, NF-κB, Interferon-Stimulated Gene Factor 3, alpha Subunit, Immunity, Innate, Virus-Cell Interactions, Cell biology, chemistry, Influenza A virus, Insect Science, biology.protein, Cytokines, Interferons, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43caa8310d0321605371450a562c1935Test
https://doi.org/10.1128/jvi.02038-20Test

المؤلفون: Yiding Zhang, Zhen Chen, Ran Cheng, Tuo Shao, Yihan Shao, Qingzhen Yu, Jun-An Ma, Kuan Hu, Xiaoyun Deng, Akiko Hatori, Steven H. Liang, Lee Josephson, Hualong Fu, Kenneth Dahl, Neil Vasdev, Michael A. Schafroth, Masayuki Fujinaga, Lin Xie, Christopher J. Fowler, Shuyin Gu, Thomas Lee Collier, Lu Wang, Benjamin F. Cravatt, Jian Rong, Daisuke Ogasawara, Tomoteru Yamasaki, Bao Liang, Yuancheng Gou, Ming-Rong Zhang, Xiaofei Zhang, Katsushi Kumata, Genwei Zhang, Wakana Mori, Jingjin Chen

المصدر: Journal of Medicinal Chemistry. 62:3336-3353

مصطلحات موضوعية: Azetidine, Proof of Concept Study, 01 natural sciences, Piperazines, Article, Rats, Sprague-Dawley, Mice, Radioligand Assay, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Tissue Distribution, Enzyme Inhibitors, Binding selectivity, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Dose-Response Relationship, Drug, medicine.diagnostic_test, Neurodegeneration, Serine hydrolase, medicine.disease, Endocannabinoid system, Monoacylglycerol Lipases, Rats, 0104 chemical sciences, Molecular Docking Simulation, Monoacylglycerol lipase, 010404 medicinal & biomolecular chemistry, chemistry, Positron emission tomography, Drug Design, Positron-Emission Tomography, Biophysics, Azetidines, Molecular Medicine, Radiopharmaceuticals

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5214207fa88d5f4a116c261d6c7b1c2Test
https://doi.org/10.1021/acs.jmedchem.8b01778Test