نتائج البحث - "Shpiro, Natalia"

1

دورية أكاديمية

Target protein localization and its impact on PROTAC-mediated degradation

المؤلفون: Simpson, Luke M., Glennie, Lorraine, Brewer, Abigail, Zhao, Jin-Feng, Crooks, Jennifer, Shpiro, Natalia, Sapkota, Gopal P.

المصدر: Simpson , L M , Glennie , L , Brewer , A , Zhao , J-F , Crooks , J , Shpiro , N & Sapkota , G P 2022 , ' Target protein localization and its impact on PROTAC-mediated degradation ' , Cell Chemical Biology , vol. 29 , no. 10 , pp. 1482-1504.e7 . https://doi.org/10.1016/j.chembiol.2022.08.004Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2022.08.004Test
https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest
https://discovery.dundee.ac.uk/ws/files/80555670/PIIS2451945622003129.pdfTest
http://www.scopus.com/inward/record.url?scp=85140068494&partnerID=8YFLogxKTest

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2

دورية أكاديمية

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

المؤلفون: Snelling, Tom, Shpiro, Natalia, Gourlay, Robert, Lamoliatte, Frederic, Cohen, Philip

المصدر: Biochemical Journal ; volume 479, issue 20, page 2195-2216 ; ISSN 0264-6021 1470-8728

الإتاحة: https://doi.org/10.1042/bcj20220401Test
https://portlandpress.com/biochemj/article-pdf/479/20/2195/938585/bcj-2022-0401.pdfTest

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3

دورية أكاديمية

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

المؤلفون: Liu, Xingui, Kalogeropulou, Alexia F., Domingos, Sofia, Makukhin, Nikolai, Nirujogi, Raja S., Singh, Francois, Shpiro, Natalia, Saalfrank, Anton, Sammler, Esther, Ganley, Ian G., Moreira, Rui, Alessi, Dario R., Ciulli, Alessio

المساهمون: Medical Research Council, Wellcome Trust, Ono Pharmaceutical, H2020 Health, Parkinson's UK, FP7 Ideas: European Research Council, Funda??o para a Ci?ncia e a Tecnologia

المصدر: Journal of the American Chemical Society ; volume 144, issue 37, page 16930-16952 ; ISSN 0002-7863 1520-5126

الإتاحة: https://doi.org/10.1021/jacs.2c05499Test

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4

دورية أكاديمية

Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader

المؤلفون: Tovell, Hannah, Testa, Andrea, Zhou, Houjiang, Shpiro, Natalia, Crafter, Claire, Ciulli, Alessio, Alessi, Dario

المصدر: Tovell , H , Testa , A , Zhou , H , Shpiro , N , Crafter , C , Ciulli , A & Alessi , D 2019 , ' Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader ' , ACS Chemical Biology , vol. 14 , no. 9 , pp. 2024-2034 . https://doi.org/10.1021/acschembio.9b00505Test

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/745f638c-acbf-4630-a11f-1dc37b0d2f72Test

الإتاحة: https://doi.org/10.1021/acschembio.9b00505Test
https://discovery.dundee.ac.uk/en/publications/745f638c-acbf-4630-a11f-1dc37b0d2f72Test
https://discovery.dundee.ac.uk/ws/files/39113819/acschembio.9b00505.pdfTest
http://www.scopus.com/inward/record.url?scp=85072509785&partnerID=8YFLogxKTest

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5

دورية أكاديمية

Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells

المؤلفون: Lopez-Pelaez, Marta, Lamont, Douglas J., Peggie, Mark, Shpiro, Natalia, Gray, Nathanael S., Cohen, Philip

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2014 Dec 01. 111(49), 17432-17437.

الوصول الحر: https://www.jstor.org/stable/43278697Test

النص الكامل

6

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase

المؤلفون: Göransson, Olga, McBride, Andrew, Hawley, Simon A., Ross, Fiona A., Shpiro, Natalia, Foretz, Marc, Viollet, Benoit, Hardie, D. Grahame, Sakamoto, Kei

المصدر: Journal of Biological Chemistry. 282(45):32549-32560

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes

الوصول الحر: https://lup.lub.lu.se/record/974337Test
http://dx.doi.org/10.1074/jbc.M706536200Test

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7

دورية أكاديمية

Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity

المؤلفون: Alsina-Beauchamp, Dayanira, Escós, Alejandra, Fajardo, Pilar, González-Romero, Diego, Díaz-Mora, Ester, Risco, Ana, Martín-Serrano, Miguel A., Del Fresno, Carlos, Dominguez-Andrés, Jorge, Aparicio, Noelia, Zur, Rafal, Shpiro, Natalia, Brown, Gordon D., Ardavín, Carlos, Netea, Mihai G., Alemany, Susana, Sanz-Ezquerro, Juan J., Cuenda, Ana

المصدر: Alsina-Beauchamp , D , Escós , A , Fajardo , P , González-Romero , D , Díaz-Mora , E , Risco , A , Martín-Serrano , M A , Del Fresno , C , Dominguez-Andrés , J , Aparicio , N , Zur , R , Shpiro , N , Brown , G D , Ardavín , C , Netea , M G , Alemany , S , Sanz-Ezquerro , J J & Cuenda , A 2018 , ' Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity ' , EMBO Molecular Medicine , vol. 10 ....

مصطلحات موضوعية: Candida albicans, infection, kinase inhibitor, p38MAPK, signalling, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/f4e75b67-4231-4f0e-a079-ccda52fe2666Test

الإتاحة: https://doi.org/10.15252/emmm.201708485Test
https://discovery.dundee.ac.uk/en/publications/f4e75b67-4231-4f0e-a079-ccda52fe2666Test
https://discovery.dundee.ac.uk/ws/files/20709641/Final_Published_Version.pdfTest

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8

دورية أكاديمية

Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

المؤلفون: Sutavani, Ruhcha V., Phair, Iain R., Barker, Rebecca, McFarlane, Alison, Shpiro, Natalia, Lang, Stuart, Woodland, Andrew, Arthur, J. Simon C.

المصدر: Sutavani , R V , Phair , I R , Barker , R , McFarlane , A , Shpiro , N , Lang , S , Woodland , A & Arthur , J S C 2018 , ' Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases ' , Journal of Biological Chemistry , vol. 293 , no. 7 , pp. 2302-2317 . https://doi.org/10.1074/jbc.M117.805424Test

مصطلحات موضوعية: Journal article, cAMP response element-binding protein (CREB), Extracellular-signal-regulated kinase (ERK), p38 MAPK, RSK, Toll-like receptor 4 (TLR4), Interleukin 10, MSK1, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/3f259a33-7980-4bab-9a08-cc026110377aTest

الإتاحة: https://doi.org/10.1074/jbc.M117.805424Test
https://discovery.dundee.ac.uk/en/publications/3f259a33-7980-4bab-9a08-cc026110377aTest
https://discovery.dundee.ac.uk/ws/files/20224891/J._Biol._Chem._2018_Sutavani_2302_17.pdfTest

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9

دورية أكاديمية

Target Protein Localisation and Its Impact on PROTAC-Mediated Degradation

المؤلفون: Simpson, Luke Martin, Glennie, Lorraine, Crooks, Jennifer, Shpiro, Natalia, Sapkota, Gopal

المصدر: SSRN Electronic Journal ; ISSN 1556-5068

مصطلحات موضوعية: Industrial and Manufacturing Engineering, Polymers and Plastics, History, Business and International Management

الإتاحة: https://doi.org/10.2139/ssrn.4006704Test

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10

دورية أكاديمية

Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling.

المؤلفون: Emmerich, Christoph, Bakshi, Siddharth, Kelsall, Ian, Ortiz-Guerrero, Juan, Shpiro, Natalia, Cohen, Philip

المصدر: Emmerich , C , Bakshi , S , Kelsall , I , Ortiz-Guerrero , J , Shpiro , N & Cohen , P 2016 , ' Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. ' , Biochemical and Biophysical Research Communications , vol. 474 , no. 3 , pp. 452-461 . https://doi.org/10.1016/j.bbrc.2016.04.141Test

مصطلحات موضوعية: Ubiquitin, innate, immunity, TNF, TLR3, NOD1, LUBAC

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/82cd1ccc-fa0d-42cd-bd21-141ecd2ab305Test

الإتاحة: https://doi.org/10.1016/j.bbrc.2016.04.141Test
https://discovery.dundee.ac.uk/en/publications/82cd1ccc-fa0d-42cd-bd21-141ecd2ab305Test
https://discovery.dundee.ac.uk/ws/files/9068470/1_s2.0_S0006291X16306647_main.pdfTest
http://www.linkedin.com/groups/Biochemical-Biophysical-Research-Communications-BBRC-7403267Test

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