المؤلفون: Denis Belitškin, Pauliina Munne, Shishir M. Pant, Johanna M. Anttila, Ilida Suleymanova, Kati Belitškina, Daniel Kirchhofer, James Janetka, Taivo Käsper, Sami Jalil, Jeroen Pouwels, Topi A. Tervonen, Juha Klefström

المصدر: Molecular Oncology, Vol 18, Iss 3, Pp 547-561 (2024)

مصطلحات موضوعية: breast cancer, EGFR, HPN, mouse cancer model, patient‐derived explant culture model, TGFβ, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1574-7891Test; https://doaj.org/toc/1878-0261Test

الوصول الحر: https://doaj.org/article/3e25433eb30948a582897944f0e227aeTest

المؤلفون: Xue Zhang, Shishir M. Pant, Cecily C. Ritch, Hsin-Yao Tang, Hongguang Shao, Harsh Dweep, Yao-Yu Gong, Rebekah Brooks, Patricia Brafford, Adam J. Wolpaw, Yool Lee, Ashani Weeraratna, Amita Sehgal, Meenhard Herlyn, Andrew Kossenkov, David Speicher, Peter K. Sorger, Sandro Santagata, Chi V. Dang

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/c859ff64da1345c9ad8da5b07e20c424Test

المؤلفون: Juha Klefström, Emmy W. Verschuren, Panu E. Kovanen, Caj Haglund, Katja Närhi, Johanna I. Englund, Denis Belitškin, Shishir M. Pant, Topi A. Tervonen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4ed27c78bf69ac46bd29a52cb8d6c245Test
https://doi.org/10.1158/0008-5472.c.6513103.v1Test

المؤلفون: Juha Klefström, Emmy W. Verschuren, Panu E. Kovanen, Caj Haglund, Katja Närhi, Johanna I. Englund, Denis Belitškin, Shishir M. Pant, Topi A. Tervonen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73134cbb6038d92209df6fd11a8d7fffTest
https://doi.org/10.1158/0008-5472.22428706.v1Test

المؤلفون: Kati Belitškina, Hanna-Ala Hongisto, Jeroen Pouwels, Olga Klezovitch, Outi Monni, Shishir M. Pant, Pirjo Laakkonen, Topi A. Tervonen, Ilida Suleymanova, Valeri Vasioukhin, Johanna Englund, Tiina Raatikainen, Satu Kuure, Shuo Li, Juha Klefström, Denis Belitskin, Qingyu Wu, Pauliina Munne

المساهمون: CAN-PRO - Translational Cancer Medicine Program, Research Programs Unit, HUSLAB, Helsinki Institute of Life Science HiLIFE, Joint Activities, Centre of Excellence in Stem Cell Metabolism, Juha Klefström / Principal Investigator, Department of Oncology, University Management, ATG - Applied Tumor Genomics, STEMM - Stem Cells and Metabolism Research Program, Helsinki Institute of Life Science HiLIFE, Infra, Biosciences, Kidney development, Pirjo Maarit Laakkonen / Principal Investigator

المصدر: EMBO Reports

مصطلحات موضوعية: medicine.medical_treatment, Cell, INVASION, Biochemistry, Extracellular matrix, Mice, 0302 clinical medicine, Transforming Growth Factor beta, Cancer, GENE-EXPRESSION, 0303 health sciences, medicine.diagnostic_test, biology, MICE DEFICIENT, Chemistry, Serine Endopeptidases, Articles, Transmembrane protein, PROSTATE-CANCER, 3. Good health, Cell biology, medicine.anatomical_structure, Cytokine, 030220 oncology & carcinogenesis, hepsin, Biotechnology, Proteolysis, Hepsin, Article, OVARIAN-CANCER, TGFβ, 03 medical and health sciences, breast cancer, fibronectin, TGF beta, MAMMARY-GLAND, TGF beta signaling pathway, Genetics, medicine, Animals, tumor microenvironment, TRANSMEMBRANE SERINE-PROTEASE, CELL, PLASMINOGEN-ACTIVATOR, Molecular Biology, 030304 developmental biology, Tumor microenvironment, GROWTH-FACTOR-BETA, Fibronectins, Fibronectin, biology.protein, 3111 Biomedicine, Cell Adhesion, Polarity & Cytoskeleton

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f63cdd7f8b5ddc2c5f2d559f76bb69aTest
https://doi.org/10.1096/fasebj.2021.35.s1.02255Test

المؤلفون: Topi A. Tervonen, Denis Belitškin, Pauliina Munne, Shishir M. Pant, Ilida Suleymanova, Kati Belitškina, Jeroen Pouwels, Juha Klefström

المصدر: Cancer Research. 82:834-834

مصطلحات موضوعية: Cancer Research, Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d595673d3dd605a8bf8eb47f2b3f4756Test
https://doi.org/10.1158/1538-7445.am2022-834Test

المؤلفون: Topi A, Tervonen, Shishir M, Pant, Denis, Belitškin, Johanna I, Englund, Katja, Närhi, Caj, Haglund, Panu E, Kovanen, Emmy W, Verschuren, Juha, Klefström

المصدر: Cancer research. 81(6)

مصطلحات موضوعية: Collagen Type IV, Carcinogenesis, MAP Kinase Signaling System, Primary Cell Culture, Breast Neoplasms, Mice, Transgenic, Cell Communication, Basement Membrane, Proto-Oncogene Proteins p21(ras), Mice, Mammary Glands, Animal, Heat Shock Transcription Factors, Cell Line, Tumor, Animals, Humans, Neoplasm Invasiveness, Breast, Protein Stability, Serine Endopeptidases, Mammary Neoplasms, Experimental, Epithelial Cells, Desmosomes, Xenograft Model Antitumor Assays, Up-Regulation, Gene Knockdown Techniques, Mutation, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::fd8e3e40ab74162ad08c8e82f84621edTest
https://pubmed.ncbi.nlm.nih.gov/33461973Test

المؤلفون: Shishir M. Pant, Vishnu C. Damalanka, James W. Janetka, Juha Klefström, Florencia La Greca, Zhenfu Han, Anthony J. O’Donoghue, Charles S. Craik, Tommy Kim, Partha Karmakar, Jonathan D.M. Helander

المصدر: Journal of medicinal chemistry. 62(2)

مصطلحات موضوعية: Proteases, Cell signaling, C-Met, Serine Proteinase Inhibitors, Hepsin, medicine.medical_treatment, Drug Evaluation, Preclinical, 01 natural sciences, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Humans, Matriptase, 030304 developmental biology, 0303 health sciences, Protease, Binding Sites, biology, Serine Endopeptidases, Dipeptides, 3. Good health, 0104 chemical sciences, Protein Structure, Tertiary, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, chemistry, Tumor progression, Cancer research, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9939c74703645ccc2d0cb608be53b36aTest
https://pubmed.ncbi.nlm.nih.gov/30571119Test

المؤلفون: Panu E. Kovanen, Emmy W. Verschuren, Juha Klefström, Johanna Englund, Denis Belitskin, Shishir M. Pant, Topi A. Tervonen

المصدر: Cancer Research. 80:LB-204

مصطلحات موضوعية: Cancer Research, Breast cancer, Oncology, Cancer research, Serine Protease Hepsin, medicine, Biology, medicine.disease, Phenotype

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a11e5b623738b1d3487e5afd87ea5215Test
https://doi.org/10.1158/1538-7445.am2020-lb-204Test

المؤلفون: Topi A. Tervonen, Shishir M. Pant, Juha Klefström, Denis Belitskin

المصدر: Extracellular Targeting of Cell Signaling in Cancer

مصطلحات موضوعية: Basement membrane, 0303 health sciences, Chemistry, Hemidesmosome, 030302 biochemistry & molecular biology, Cell, Cancer, medicine.disease, Transmembrane protein, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, medicine, Serine Protease Hepsin, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bfa1380cf4347880e2165d232745df32Test
https://doi.org/10.1002/9781119300229.ch5Test