دورية أكاديمية
xenoGI 3: using the DTLOR model to reconstruct the evolution of gene families in clades of microbes
العنوان: | xenoGI 3: using the DTLOR model to reconstruct the evolution of gene families in clades of microbes |
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المؤلفون: | Nuo Liu, Tonatiuh A. Gonzalez, Jacob Fischer, Chan Hong, Michelle Johnson, Ross Mawhorter, Fabrizia Mugnatto, Rachael Soh, Shifa Somji, Joseph S. Wirth, Ran Libeskind-Hadas, Eliot C. Bush |
المصدر: | BMC Bioinformatics, Vol 24, Iss 1, Pp 1-14 (2023) |
بيانات النشر: | BMC, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Computer applications to medicine. Medical informatics LCC:Biology (General) |
مصطلحات موضوعية: | Reconciliation, Gene family, Horizontal transfer, Genomic island, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5 |
الوصف: | Abstract To understand genome evolution in a group of microbes, we need to know the timing of events such as duplications, deletions and horizontal transfers. A common approach is to perform a gene-tree / species-tree reconciliation. While a number of software packages perform this type of analysis, none are geared toward a complete reconstruction for all families in an entire clade. Here we describe an update to the xenoGI software package which allows users to perform such an analysis using the newly developed DTLOR (duplication-transfer-loss-origin-rearrangement) reconciliation model starting from genome sequences as input. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1471-2105 |
العلاقة: | https://doaj.org/toc/1471-2105Test |
DOI: | 10.1186/s12859-023-05410-0 |
الوصول الحر: | https://doaj.org/article/84ac1faa233f42b0bd6e5763ddfeac6fTest |
رقم الانضمام: | edsdoj.84ac1faa233f42b0bd6e5763ddfeac6f |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14712105 |
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DOI: | 10.1186/s12859-023-05410-0 |