كتاب
Effects of irregular cerebrospinal fluid production rate in human brain ventricular system
| العنوان: | Effects of irregular cerebrospinal fluid production rate in human brain ventricular system |
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| المؤلفون: | Hadzri, Edi Azali, Shamsudin, Amir Hamzah, Osman, Kahar, Abdul Kadir, Mohammed Rafiq, Abdul Aziz, Azian |
| بيانات النشر: | American Institute of Physics |
| سنة النشر: | 2012 |
| المجموعة: | Universiti Teknologi Malaysia: Institutional Repository |
| مصطلحات موضوعية: | TJ Mechanical engineering and machinery |
| الوصف: | Hydrocephalus is an abnormal accumulation of fluid in the ventricles and cavities in the brain. It occurs when the cerebrospinal fluid (CSF) flow or absorption is blocked or when excessive CSF is secreted. The excessive accumulation of CSF results in an abnormal widening of the ventricles. This widening creates potentially harmful pressure on the tissues of the brain. In this study, flow analysis of CSF was conducted on a three-dimensional model of the third ventricle and aqueduct of Sylvius, derived from MRI scans. CSF was modeled as Newtonian Fluid and its flow through the region of interest (ROI) was done using EFD. Lab software. Different steady flow rates through the Foramen of Monro, classified by normal and hydrocephalus cases, were modeled to investigate its effects. The results show that, for normal and hydrocephalus cases, the pressure drop of CSF flow across the third ventricle was observed to be linearly proportionally to the production rate increment. In conclusion, flow rates that cause pressure drop of 5 Pa was found to be the threshold for the initial sign of hydrocephalus. |
| نوع الوثيقة: | book part |
| اللغة: | unknown |
| العلاقة: | Hadzri, Edi Azali and Shamsudin, Amir Hamzah and Osman, Kahar and Abdul Kadir, Mohammed Rafiq and Abdul Aziz, Azian (2012) Effects of irregular cerebrospinal fluid production rate in human brain ventricular system. In: 4Th International Meeting of Advances in Thermofluids (Imat 2011), Pt 1 And 2. American Institute of Physics, Maryland, New York, pp. 659-664. ISBN 978-073541032-9 |
| DOI: | 10.1063/1.4704275 |
| الإتاحة: | https://doi.org/10.1063/1.4704275Test http://eprints.utm.my/35755Test/ |
| رقم الانضمام: | edsbas.7D4C0171 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1063/1.4704275 |
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